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Studying the performance of pavement defects at different road slopes using the vibration-based method and deep machine learning

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Journal of Traffic and Transportation Engineering(English Edition) 2024年第6期11卷 1259-1267页

作者： amir Shtayat Department of City Planning and Design Jordan University of Science & Technology

Road networks are the backbone of urban life and significantly impact the sustainability of any country's infrastructure sector. Therefore, it is necessary to maintain the condition of roads and pavements through continuous monitoring and periodic maintenance in order to achieve the highest levels of service for road users and the sustainability of their *** is the main component of road networks, providing the highest degree of comfort to drivers and roadway users when it is appropriately designed and free from defects and cracks. More clearly, defects are one of the most important factors that reduce the operational life of roads and cause economic losses to road users by causing damage to their vehicles; moreover, the damaged pavement needs frequent and long maintenance that may also drain the resources of government institutions and transport ***, there is a crucial need for a monitoring and follow-up system for the condition of the roads in order to identify and treat defects quickly. This study used a vibration-based system to monitor pavement conditions on several roads with different gradients. A fully electric car was used to determine the vibration values, which indicate the degree of driving comfort, to determine the spread and behaviour of defects on the pavement at multiple locations on roads with different gradients. Also, a machine learning model was applied using a “decision tree” model to identify, classify and predict defects on the pavements. The results of this study indicated that pavement defects were more prevalent in the first and last quadrants of the high-slope roads compared to the low-slope roads. The prediction model achieved accuracy in predicting the performance of defects with a rate of 94% for roads with low gradients and 90% and 86% for roads with medium and high gradients, respectively.

关键词： Pavement defect Road slope Vibration Prediction Gradients

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Salivary gland antigens of laboratory-bred Phlebotomus sergenti and their immunogenicity in human volunteers in laboratory condition

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Asian Pacific Journal of Tropical Medicine 2020年第1期13卷 17-23页

作者： Arshad Veysi Ahmad reza Mahmoudi Mohammad reza Yaghoobi-Ershadi Mahmood Jeddi-Tehrani Yavar Rassi Alireza Zahraei-Ramazani Nasibeh Hosseini-Vasoukolaei Daem Roshani Mahboubeh Fatemi Ali Khamesipour amir Ahmad Akhavan Zoonoses Research Center Research Institute for Health DevelopmentKurdistan University of Medical sciencesSanandajIran Department of Medical Entomology and Vector Control School of Public HealthTehran University of Medical SciencesTehranIran Immunology Research Center Institute of Immunology and Infectious DiseasesIran University of Medical SciencesTehranIran Monoclonal Antibody Research Center Avicenna Research InstituteACECRTehranIran Department of Medical Entomology and Vector Control Health Sciences Research CenterAddiction InstituteMazandaran University of Medical SciencesSariIran Social Determinants of Health Research Center Research Institute for Health DevelopmentKurdistan University of Medical SciencesSanandajIran Center for Research and Training in Skin Diseases and Leprosy Tehran University of Medical SciencesTehranIran

Objective:To investigate Phlebotomus(P.)sergenti Parrot,1917(Diptera:Psychodidae)salivary gland antigens and their immune response in ***:Human volunteers were exposed to sand flies’bites in the laboratory,and following each exposure the size of induration was *** mean protein concentration of salivary gland lysate and specific *** saliva IgG was *** fly salivary proteins were separated by SDS-PAGE and their immunoreactivity was examined by Western blotting ***:Individuals exposed to *** salivary gland lysate for 8 months showed both antibody and delayed type hypersensitivity responses,although exposure for one month did not provoke any immune *** trend of antibody fluctuated during the exposure time and dropped by the end of antigen *** mean protein content was(0.36±0.08)μg in each pair salivary *** gland lysate showed 11 to 12 major protein bands and 3 to 6 of them were ***:Our study showed that the salivary gland components of *** provoked both cellular and humoral immune responses in ***,there are some immunogenic proteins in *** saliva which could be subjected for further investigation as vector-based vaccine candidate/s against anthroponotic cutaneous leishmaniasis.

关键词： Phlebotomus sergenti Antibody response Delayed-type hypersensitivity Human Salivary gland antigen

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Enhancing the Robustness of Visual Object Tracking via Style Transfer

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Computers, Materials & Continua 2022年第1期70卷 981-997页

作者： Abdollah amirkhani amir Hossein Barshooi amir Ebrahimi School of Automotive Engineering Iran University of Science and TechnologyTehran16846-13114Iran School of Electrical Engineering and Computing The University of NewcastleCallaghan2308Australia

The performance and accuracy of computer vision systems are affected by noise in different *** numerous solutions and algorithms have been presented for dealing with every type of noise,a comprehensive technique that can cover all the diverse noises and mitigate their damaging effects on the performance and precision of various systems is still *** this paper,we have focused on the stability and robustness of one computer vision branch(i.e.,visual object tracking).We have demonstrated that,without imposing a heavy computational load on a model or changing its algorithms,the drop in the performance and accuracy of a system when it is exposed to an unseen noise-laden test dataset can be prevented by simply applying the style transfer technique on the train dataset and training the model with a combination of these and the original untrained *** verify our proposed approach,it is applied on a generic object tracker by using regression *** method’s validity is confirmed by testing it on an exclusive benchmark comprising 50 image sequences,with each sequence containing 15 types of noise at five different intensity *** OPE curves obtained show a 40%increase in the robustness of the proposed object tracker against noise,compared to the other trackers considered.

关键词： Style transfer visual object tracking robustness corruption

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Limb Lengthening and Reconstruction Society orthopedic surgeons in the United States:An analysis of geographical distribution,academic,leadership,and demographic characteristics

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World Journal of Orthopedics 2024年第2期15卷 147-155页

作者： amir Human Hoveidaei reza Niakan Seyed Hossein Hosseini-Asl Abijith Annasamudram Janet D Conway International Center for Limb Lengthening Rubin Institute for Advanced OrthopedicsSinai Hospital of BaltimoreBaltimoreMD 21215United States Student Research Committee Shiraz University of Medical SciencesShiraz 73Iran Students’Scientific Research Center Tehran University of Medical SciencesTehran ***Iran

BACKGROUND The Limb Lengthening and Reconstruction Society(LLRS)is a premier orthopedic specialty organization that promotes limb reconstruction for all *** membership characteristics,however,are poorly *** study delineates orthopedic surgeon LLRS members’demographic traits,academic achievement,leadership attainment,and geographical distribution across the United *** To inform aspiring orthopedic professionals,as well as to promote growth and diversity in both the LLRS organization and overarching *** This cross-sectional study examined United States LLRS members’academic,leadership,demographic,and geographical *** reviewing the 2023 LLRS member directory,Google search results were matched to the listings and appended to the compiled *** and ethnicity were evaluated visually utilizing retrieved *** Hirsch index(H-index)of academic activity,residency and fellowship training,other graduate degrees,leadership positions,practice type(academic or non-academic),and spoken languages were *** members per state and capita determined geographic *** Mann Whitney U test was applied to compare H-index between males and females,as well as to assess member differences pertaining to affiliation with academic vs non-academic practice *** The study included 101 orthopedic surgeons,78(77.23%)Caucasian and 23(22.77%)non-Caucasian,79(78.22%)male and 22(21.78%)*** with DO degrees comprised only 3.96%(4)of the cohort,while the vast majority held MDs[96.04%(97)].Mean H-index was 10.55,with male surgeons having a significantly higher score(P=0.002).Most orthopedic surgeons(88.12%,)practiced in academic *** those professionals who occupied leadership positions,14%were women,while 86%were ***,19(37.25%)United States regions and the District of Columbia lacked an LLRS-member orthopedic *** per capita rate across the United States was 0.30 LLRS orthopedic

关键词： Limb lengthening and reconstruction Orthopedic surgeon demographics Orthopedic surgeon societal membership Orthopedic fellowships

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Antimicrobial Assay of Chlorhexidine-Wetted Textile Napkins for Surgical Site Disinfection in Ocular Surgery

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International Journal of Clinical Medicine 2013年第12期4卷 577-581页

作者： amir reza Daneshmand Eslami Department of Ophthalmology National Medical Academy of Postgraduate Education Kiev Ukraine

Background: As a new intraoperative disinfection method, chlorhexidine-wetted textile napkins have been employed in order to cover the upper and lower eyelid edges, eyelid skin, eyelashes, lid margins and palpebral conjunctiva during phacoemulsification cataract extraction. This study was conducted to compare the antimicrobial activity of textile napkins before and after their use. Methods: This study evaluated 80 textile napkins wetted with 0.02% aqueous solution of chlorhexidine. All textile napkins were divided into groups. The study group consisted of 60 used textile napkins which were collected from 29 patients (30 eyes) at the end of phacoemulsification, and the control group included 20 unused sterile textile napkins. Antimicrobial assay was performed by means of measuring the growth inhibition zones of the standard or clinical isolate strains under the textile napkins on the surface of agar media. Results: The number of textile napkins and the diameter of the growth inhibition zones (mm) in the study group and in the control group relating to gram-positive, gram-negative, and fungi were: 24/31 vs. 8/31, 32/30 vs. 8/30, and 4/30 vs. 4/30. The diameter of the growth inhibition zones of gram-positive bacteria was more than other investigated microorganisms. In the growth inhibition zones, exogenous microorganism colonies were not found. Conclusion: Antimicrobial activity of textile napkins wetted with 0.02% aqueous solution of chlorhexidine against gram-positive bacteria is more than gram-negative bacteria and fungi, and is preserved to the end of the phacoemulsification.

关键词： Chlorhexidine Endophthalmitis Levofloxacin Phacoemulsification Surgical Site Disinfection

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CAR-T cells: Early successes in blood cancer and challenges in solid tumors

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Acta Pharmaceutica Sinica B 2021年第5期11卷 1129-1147页

作者： Hassan Dana Ghanbar Mahmoodi Chalbatani Seyed amir Jalali Hamid reza Mirzaei Stephan A.Grupp Eloah Rabello Suarez Catarina Raposo Thomas J.Webster Cancer Research Center Cancer Institute of IranTehran University of Medical SciencesTehran 13145-158Iran Department of Medical Immunology School of MedicineTehran University of Medical SciencesTehran ***Iron Department of Immunology School of MedicineShahid Beheshti University of Medical SciencesTehran ***Iran Division of Oncology Department of Pediatricsthe Children's Hospital of PhiladelphiaPhiladelphiaPA 19104USA Center for Natural and Human Sciences Federal University of ABCSanto AndreSP 09210-580Brazil Faculty of Pharmaceutical Sciences State University of Campinas(UNICAMP)CampinasSP 13083-87JBrazil Department of Chemical Engineering Northeastern UniversityBostonMA 02115USA

New approaches to cancer immunotherapy have been developed, showing the ability to harness the immune system to treat and eliminate cancer. For many solid tumors, therapy with checkpoint inhibitors has shown promise. For hematologic malignancies, adoptive and engineered cell therapies are being widely developed, using cells such as T lymphocytes, as well as natural killer(NK) cells, dendritic cells, and potentially others. Among these adoptive cell therapies, the most active and advanced therapy involves chimeric antigen receptor(CAR)-T cells, which are T cells in which a chimeric antigen receptor is used to redirect specificity and allow T cell recognition, activation and killing of cancers, such as leukemia and lymphoma. Two autologous CAR-T products have been approved by several health authorities,starting with the U.S. Food and Drug Administration(FDA) in 2017. These products have shown powerful, inducing, long-lasting effects against B cell cancers in many cases. In distinction to the results seen in hematologic malignancies, the field of using CAR-T products against solid tumors is in its infancy. Targeting solid tumors and trafficking CAR-T cells into an immunosuppressive microenvironment are both significant challenges. The goal of this review is to summarize some of the most recent aspects of CAR-T cell design and manufacturing that have led to successes in hematological malignancies, allowing the reader to appreciate the barriers that must be overcome to extend CAR-T therapies to solid tumors successfully.

关键词： Immunotherapy T cell therapy Chimeric antigen receptor(CAR) Genetic engineering

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Effects of the deep rolling process on the surface roughness and properties of an Al-3vol%SiC nanoparticle nanocomposite fabricated by mechanical milling and hot extrusion

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International Journal of Minerals,Metallurgy and Materials 2017年第7期24卷 814-825页

作者： Sajjad Sattari amir Atrian Department of Mechanical Engineering Najafabad Branch Islamic Azad University Najafabad Iran Modem Manufacturing Technologies Research Center Najafabad Branch Islamic Azad University Najafabad lran

Deep rolling is one of the most widely used surface mechanical treatments among several methods used to generate compressive residual stress. This process is usually used for axisymmetric components and can lead to improvements of the surface quality, dimensional accuracy, and mechanical properties. In this study, we deduced the appropriate deep rolling parameters for Al-3vol%Si C nanocomposite samples using roughness and microhardness measurements. The nanocomposite samples were fabricated using a combination of mechanical milling, cold pressing, and hot extrusion techniques. Density measurements indicated acceptable densification of the samples, with no porosity. The results of tensile tests showed that the samples are sufficiently strong for the deep rolling process and also indicated near 50% improvement of tensile strength after incorporating Si C nanoparticle reinforcements. The effects of some important rolling parameters, including the penetration depth, rotation speed, feed rate, and the number of passes, on the surface quality and microhardness were also investigated. The results demonstrated that decreasing the feed rate and increasing the number of passes can lead to greater surface hardness and lower surface roughness.

关键词： deep rolling nanocomposite mechanical milling hot extrusion roughness hardness

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Mechanical Properties and Microstructure Evolution of AA1100 Aluminum Sheet Processed by Accumulative Press Bonding Process

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Acta Metallurgica Sinica(English Letters) 2016年第8期29卷 735-741页

作者： amir Mostafapor Vahid Mohammadinia Department of Mechanical Engineering University of Tabriz Department of Mechanical Engineering University of Maragheh

Accumulative press bonding（APB） is a novel variant of severe plastic deformation processes,which is devised to produce materials with ultra-fine *** the present work,the mechanical properties and microstructural evolution of AA1100 alloy,which is produced by APB technique,were *** study of the microstructure of AA1100 alloy was performed by optical *** results revealed that the grain size of the samples decreased to 950 nm after six passes of APB *** yield strength of AA1100 alloy after six passes of the process increased up to 264 MPa,which is three times higher than that of the as-cast material（89 MPa）.After six passes,microhardness values of AA1100 alloy increased from 38 to 61 ***,the results showed that the behavior of variations in mechanical properties is in accordance with the microstructural changes and it can be justified by using the Hall-Patch ***,the rise in the yield strength can be attributed to the reduction in the grain size leading to the strain hardening.

关键词： Severe plastic deformation Accumulative press bonding Mechanical properties Metallurgical properties AA1100 alloy

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Ion separation and water purification by applying external electric field on porous graphene membrane

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Nano Research 2018年第4期11卷 2229-2236页

作者： amir Lohrasebi Samaneh Rikhtehgaran Department of Physics University of Isfahan Isfahan 81746-73441 Iran School of Nano Science Institute for Research in Fundamental Sciences (IPM) Tehran 19395-5531 Iran Department of Physics Florida Atlantic University 777 Glades Road Boca Raton FL 33431-0991 USA

Using molecular dynamics （MD） simulations, a porous graphene membrane was exposed to external electric fields to separate positive and negative ions from salt-water and to produce fresh water. It was observed that, by increasing the strength of the applied electric field, ion separation improved noticeably. In addition, to obtain fresh water, the designed system included two graphene membranes, which are exposed to two external electric fields in opposite directions. Ion rejection was found to be greater than 93% for the electric field of 10 mV/A and higher. This atomic-level simulation increases the understanding of electric field effects on desalination using multilayer graphene membranes and can be helpful in designing more efficient membranes.

关键词： desalination nanoporous graphene membrane ion separation molecular dynamicss imulation electric field

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Microstructural Evolution of NiTi47.7Cu6.3 Alloy during Hot Deformation

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Journal of Materials Science & Technology 2011年第10期27卷 951-960页

作者： amir Etaati Kamran Dehghani Mining and Metallurgical Eng.Dept. Amirkabir Univ.Tech.

In the present work, the hot workability and microstructural evolution of ***6.3 （at.%） shape memory alloy were investigated by using wedge-rolling test. The wedge specimens were subjected to hot rolling at the temperatures of 700-1000℃. The microstructural evolutions at the strains of 0.05, 0.15, 0.2, 0.25 and 0.3 were then characterized by optical microscopy and scanning electron microscopy （SEM） as well as energy dispersive spectrometry （EDS） technique. Depending on the deformation temperature and strain, the dynamic recrystallization （DRX） could occur, leading to the refining of the microstructure. At low temperatures of 700 and 800℃ there was no sign of DRX at all studied strains. At these temperatures, the formed fine needle-like precipitates pinned the grain boundaries and prevented them from bulging/migration. By contrast, at higher temperatures of 900 and 1000℃, the DRX took place at the critical strains lower than 0.25 and 0.15, respectively. However, at higher temperatures, strain-induced-boundary-migration （SIBM） mechanism resulted in the formation of DRX grains.

关键词： Deformation Wedge rolling test Dynamic recrystallization Ni-rich Nitinol NiTiCu

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