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Diabetes during COVID-19 Pneumonia in a 16-Year-Old Girl: A Case Report in Cameroon

Open Journal of Pediatrics 2024年第4期14卷 712-718页

作者： Ritha Mbono Betoko Charlotte Eposse Suzanne Sap betsy bate Gaelle Ntsoli Hassanatou Iyawa Calixte Ida Penda Faculty of Medicine and Pharmaceutical Sciences University of Douala Douala Cameroon Laquintinie Douala Hospital Douala Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde I Yaound Cameroon

Background: Diabetes is a known risk factor for susceptibility and severity of COVID-19 infection. It may also be a complication of COVID-19. Many hypotheses have been proposed to explain this condition. It may be due to the effect of SARS-CoV-2 on β cells or drug-related side effects. In children, there is a paucity of data on the burden of this complication. Objective: We aimed to report a case of secondary diabetes during COVID-19 in a pediatric unit. Case Presentation: A 16-year-old girl presented with severe respiratory distress. She was treated for COVID-19 infection with antibiotics and corticosteroids. On day 6 of treatment, she developed polyuria and polydipsia. A random blood glucose test showed hyperglycaemia. The diagnosis of secondary diabetes was maintained. Conclusion: Covid-19 infection can be complicated by diabetes in children. It is essential to monitor blood glucose levels regularly.

关键词： Covid-19 Diabetes Adolescents

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Insulin Sensitivity and Gynaecological Features of Infertile Cameroonian Females with Polycystic Ovary Syndrome: A Cross-Sectional Study

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Open Journal of Obstetrics and Gynecology 2017年第13期7卷 1247-1254页

作者： Julius Sama Dohbit Eugene Sobngwi Jean Dupont Kemfang Pascal Foumane Joel Noutakdie Tochie Felix A. Elong betsy bate Emile T. Mboudou Department of Obstetrics and Gynaecology Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaounde 1 Cameroon Department of Internal Medicine and Endocrinology Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaounde 1 Cameroon Faculty of Medicine and Biomedical Sciences University of Yaounde 1 Yaounde 1 Cameroon Department of Obstetrics-Gynaecology and Surgery Faculty of Health Science University of Buea Buea Cameroon

Background: Polycystic ovary syndrome (PCOS), characterized by ovulatory dysfunction, polycystic ovary(PCO),hyperandrogenism and insulin resistance is the commonest endocrine disorder in women of reproductive age. It is an intriguing pathology that involves the perpetuation of a vicious circle with reproductive, endocrine and metabolic components. We aimed to assess the reproductive features and insulin sensitivity (IS) in infertile women with or without PCOS. Materials and Methods: We carried out a cross-sectional analytic study at the outpatient Obstetrics and Gynaecology Department of the Yaounde Gyneco-obstetric and Pediatrics Hospital, Cameroon from September 1st 2012 to March 31st 2013 giving total study duration of 07 months. Laboratory analyses were carried out at the National Obesity Centre(NOC)of the Yaounde Central Hospital, Cameroon. Results: Overall, 36 infertile females were enrolled, which included 15 diagnosed cases of PCOS according to Rotterdam consensus meeting of 2003 and 21 non PCOS subjects as control. PCOS women were younger than non PCOS women (28.8 ± 5.5 vs. 35.0 ± 4.2 years;p = 0.0004). The majority of the women in the PCOS group were spaniomenorrheic (11/15), and ultrasonographic findings were typical of PCOS. Hirsutism score was higher in the PCOS group with a median of 9 (7 - 13). Insulin sensitivity was impaired in two-thirds of the study population, with 12 women found to be insulin resistant(6 PCOS, 6 non PCOS), 12 patients had intermediate insulin sensitivity(2 PCOS, 10 non PCOS)and 12 insulin sensitive(7 PCOS, 5 non PCOS). Apart from blood glucose levels (p = 0.007), all other anthropometric and biological parameters were not significant. Spearman’s correlation identified fasting plasma glucose and total cholesterol as factors associated with insulin sensitivity in females with PCOS. Impaired fasting glucose was observed in 13 patients with 08 from the PCOS group. Conclusion: We conclude that young age, spaniomenorrhea and hirsutism

关键词： Gynaecological Features Insulin Sensitivity Impaired Fasting Blood Sugar Infertility PCOS

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