检索结果-南通市图书馆

Relationships between testate amoeba communities and water quality in Lake Donghu, a large alkaline lake in Wuhan, China

在线全文

学校读者我要写书评

暂无评论

Frontiers of Earth Science 2013年第2期7卷 182-190页

作者： Yangmin QIN bertrand.fournier Enrique LARA Yansheng GU Hongmei WANG Yongde CUI Xiaoke ZHANG Edward A. D. MITCHELL State Key Laboratory of Biogeology and Environmental Geology China University of Geosciences Wuhan 430074 China State Key Laboratory of Loess and Quaternary Geology Institute of Earth Environment Chinese Academy of Sciences Xi'an 710075 China Laboratory of Soil Biology University of Neuchatel Rue Emile Argand 11 CH-2000 Neuchatel Switzerland Institute of Hydrobiology Chinese Academy of Sciences Wuhan 430072 China

The middle Yangtze Reach is one of the most developed regions of China. As a result, most lakes in this area have suffered from eutrophication and serious environmental pollution during recent decades. The aquatic biodiversity in the lakes of the area is thus currently under significant threat from continuous human activities. Testate amoebae （TA） are benthic （rarely planktonic） microorganisms characterized by an agglutinated or autogenous shell. Owing to their high abundance, preservation potential in lacustrine sediments, and distinct response to environmental stress, they are increasingly used as indicators for monitoring water quality and reconstructing palaeoenvironmental changes. However this approach has not yet been developed in China. This study presents an initial assessment of benthic TA assemblages in eight lakes of Lake Donghu in the region of Wuhan, China. Testate amoeba community structure was most strongly correlated to water pH. In more alkaline conditions, communities were dominated by Centropyxis aculeata, Difflugia oblonga, Pontigulasia compressa, Pon. elisa and Lesquereusia modesta. These results are consistent with previous studies and show that TA could be useful for reconstructing past water pH fluctuations in China. To achieve this, the next step will be to expand the database and build transfer function models.

关键词： testate amoebae (TA) water quality water pH Lake Donghu China

Immunotoxic effects of an industrial waste incineration site on groundwater in rainbow trout (Oncorhynchus mykiss)

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2014年第5期26卷 981-990页

作者： Nadjet Benchalgo Franois Gagn Michel fournier INRS-Institut Armand-Frappier Emerging Methods Aquatic Contaminant Research Division

The discharge of organic waste from the petrochemical industry into the Mercier lagoons caused major groundwater contamination. The objective of this study was to determine the immunotoxic potential of three groundwater wells at increasing distance from the incinerator dumping site （1.17, 2.74 and 5.40 km）. Rainbow Trout were exposed to increasing concentrations of water from three groundwater wells for 14 days. Immunocompetence was characterized by phagocytosis, mitogen-stimulated proliferation of lymphocytes, cell cycle analysis and apoptosis. A significant increase in innate （phagocytosis） and specific immune response （B lymphocyte proliferation） was observed in trout exposed to water collected from the well at 2.74 km. However, phagocytosis activity was suppressed in groups at 1.17 and 5.40 km. The proportion of lymphocytes in S phase was significantly increased in groups at 2.74 and 5.40 kin, while lymphocytes in G0/G1 phase were decreased in all three exposure groups. Additionally, dexamethasone （DEX）-induced apoptosis of lymphocytes was significantly reduced in the group at 2.74 km, which suggests decreased lymphocyte turnover. Furthermore, the ratio of DEX- induced apoptosis/apoptosis was lower in the groups at 2.74 and 5.40 km. In summary, our experiments have shown that exposure to the mixture of organic compounds present in Mercier groundwater modulates phagocytosis and cell proliferation, disrupts the cell cycle and reduces the ratio of DEX- induced apoptosis/apoptosis. It is concluded that groundwater collected in the vicinity of an incinerator containment field could impact immunocompetence in fish.

关键词： groundwater phagocytosis lymphocyte proliferation cell cycle apoptosis rainbow trout

Effects of a municipal effluent on the freshwater mussel Elliptio complanata following challenge with Vibrio anguillarum

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2015年第11期27卷 91-99页

作者： Gagne Francois Douville Melanie Fortier Marlene fournier Michel Aquatic Contaminants Research Division Water Science and Technology INRS-Institut Armand-Frappier

The purpose of this study was to examine the cumulative effects of exposure to a pathogenic bacteria and municipal effluent in the freshwater mussel Elliptio complanata. Mussels were exposed to increasing concentrations of an ozone-treated effluent at 15°C for 7 days. A sub-group of mussels was inoculated with Vibrio anguillarum and exposed to the same conditions as *** the exposure period, mussels were collected to assess hemocyte count and viability,immunocompetence（phagocytosis and nitrite production）, oxidative stress/inflammation（cyclooxygenase and lipid peroxidation） and oxygen radical/xenobiotic scavenging activity（metallothioniens, glutathione S-transferase）. The results showed that mussels exposed to municipal effluent had increased hemocyte counts, phagocytosis, nitrites, lipid peroxidation and metallothioneins. In the inoculated mussels, the same responses were observed, in addition to cyclooxygenase and glutathione S-transferase activities. Multivariate analyses revealed that（1）the response pattern changed with effluent concentration, where increased responses observed at low effluent concentrations（〉10%, V/V） were attenuated at higher effluent concentrations,（2）the effluent produced more pronounced changes in lipid peroxidation, metallothionein and hemocyte viability, and（3） the simultaneous presence of V. anguillarum led to more important changes in hemocyte count and viability and nitrite levels. In conclusion, the presence of *** could alter the response of mussels to municipal effluent, which could lead to increased inflammation in mussels.

关键词： Elliptio complanata Immunocompetence Oxidative stress Inflammation Vibrio anguillarum

Targeting 14-3-3 adaptor protein-protein interactions to stimulate central nervous system repair

在线全文

学校读者我要写书评

暂无评论

Neural Regeneration Research 2017年第7期12卷 1040-1043页

作者： Andrew Kaplan Alyson E.fournier Department of Neurology and Neurosurgery Montreal Neurological Institute McGill University Montr6al Qu4bec Canada

The goal of developing treatments for central nervous system（CNS）injuries is becoming more attainable with the recent identification of various drugs that can repair damaged *** discoveries have stemmed from screening efforts,large expression datasets and an improved understanding of the cellular and molecular biology underlying axon *** will be important to continue searching for new compounds that can induce axon *** we describe how a family of adaptor proteins called 14-3-3s can be targeted using small molecule drugs to enhance axon outgrowth and regeneration.14-3-3s bind to many functionally diverse client proteins to regulate their *** highlight the recent discovery of the axon-growth promoting activity of fusicoccin-A,a fungus-derived small molecule that stabilizes 14-3-3 interactions with their client *** we discuss how fusicoccin-A could serve as a starting point for the development of drugs to induce CNS repair.

关键词： axon regeneration 14-3-3 gcnl, fusicoccin optic nerve spinal cord injury

Immunotoxic potential of aeration lagoon effluents for the treatment of domestic and hospital wastewaters in the freshwater mussel Elliptio complanata

在线全文

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2012年第5期24卷 781-789页

作者： Francois Gagné Chantale André Marlène Fortier Michel fournier Fluvial Ecosystem Research Environment Canada Montréal Quebec H2Y 2E7 Canada INRS-Institut Armand-Frappier Laval Québec Canada

Municipal wastewaters are major sources of pollution for the aquatic biota. The purpose of this study was to determine the levels of some pharmaceutical products and the immunotoxic potential of a municipal wastewater aeration lagoon for the treatment of the domestic wastewaters of a small town with wastewater inputs from a 400-bed hospital complex. Endemic mussels were collected, caged and placed in the final aeration lagoon and at sites 1 km upstream and 1 km downstream of the effluent outfall in the receiving river for a period of 14 days. The results showed that the final aeration lagoon contained high levels of total coliforms, conductivity and low dissolved oxygen （2.9 mg/L） as well as detectable amounts of trimethoprim, carbamazepine, gemfibrozil, and norfloxacin at concentrations exceeding 50 ng/L. The lagoon effluent was indeed toxic to the mussel specimens, as evidenced by the appearance of mortality after 14 days （10% mortality）, decreased mussel weight-to-shell-length ratio and loss of hemocyte viability. The number of adhering hemocytes, phagocytic activity, total nitrite levels and arachidonic cyclooxygenase activity were significantly higher in mussels placed in the final aeration lagoon. A multivariate analysis also revealed that water pH, conductivity, total coliforms and dissolved oxygen were the endpoints most closely linked with phagocytic activity, the amount of adhering hemocytes and loss of hemocyte viability. In conclusion, exposure of mussels to treated aerated lagoon wastewater is deleterious to freshwater mussels where the immune system is compromised.

关键词： mussels municipal wastewaters immunocompetence inflammation cyclooxygenase activity

Assessing Leak Paths in the Cement Sheath of a Cased Borehole by Analysis of Monopole Wavefield Modes

在线全文

学校读者我要写书评

暂无评论

Communications in Computational Physics 2020年第6期28卷 424-441页

作者： Hua Wang Michael Fehler Aiḿe fournier University of Electronic Science and Technology of China ChengduSichuan611731P.R.China Earth Resources Laboratory Massachusetts Institute of TechnologyCambridgeMA02139USA

Evaluation of possible leakage pathways of CO_(2) injected into geological formations for storage is essential for successful Carbon Capture and Storage(CCS).A channel in the borehole cement,which secures the borehole casing to the formation,may allow CO_(2) to *** assessment and remediation decisions about the pres-ence of such channels depend on channel parameters:radial position r from the center of the borehole;channel thickness d;azimuthal positionφof the channel;and az-imuthal extentθof the *** state-of-the-art cement-bond logging technology,which uses only the first arrival at a centralized borehole receiver,can diagnose limited details about CO_(2) leak *** accurately characterize the possible leak paths in the cement,we use a 3-dimensional finite-difference method to investigate the use of the abundant data collected by a modernized monopole sonic tool that contains an array of azimuthally distributed *** also investigate how to improve the tool design to acquire even more useful *** cases where borehole fluid is either water or supercritical CO_(2),we investigate various receiver geometries,multi-modal analyses of multi-frequency data to discover the type of logging tool that provides the best information for CCS *** find that an appropriate choice of wave modes,source frequencies,source polarities,and receiver locations and off-sets provides sensitivity to d,φ,θ.The amplitude of the first arrival from a monopole source is sensitive toθ.Amplitudes at receivers at different azimuths are sensitive toφ.The slow Stoneley mode(ST2)velocity is sensitive to d,but ST2 is not easy to pick whenθand d are *** improvement is necessary to provide comprehensive information about possible flow channels in casing cement.

关键词： Greenhouse effect CO_(2)leak channel cement bond evaluation borehole acoustic logging casing wave Stoneley waves

TOWARDS AN ENERGY EFFICIENT FUTURE:THE ILLINOIS SMART ENERGY DESIGN ASSISTANCE PROGRAM

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Green Building 2007年第3期2卷 52-58页

作者： Donald fournier Brian Deal Building Research Council University of Illinois at Urbana-Champaign Department of Urban and Regional Planning University of Illinois at Urbana-Champaign

*** Buildings and building related activities represent one of the largest energy consuming sectors in the United *** Illinois,from 1950 to 1990 a population increase of approximately 2.7 million translated into dramatic natural resource consumption *** example,Illinois residents currently require almost 30 million gallons of petroleum per *** to the *** of Energy,annual energy expenditures in the State have now reached over$34 billion with commercial buildings consuming over$5.6 billion *** represents an increase of over$14 billion since *** energy consumption in Illinois amounts to 3.96 quadrillion BTUs,nearly two-thirds of which can be attributed to buildings and building related consumers.

关键词： consuming alone attributed

In vitro immunotoxicity of untreated and treated urbanwastewaters using various treatment processes to rainbow trout leucocytes

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Environmental Sciences 2013年第7期25卷 1400-1407页

作者： Franois Gagné Marlène Fortier Michel fournier Shirley-Anne Smyth Emerging Methods Aquatic Contaminants Research Division Water Science and Technology Environment Canada105 McGill Street Montral Qubec Canada INRS-Institut Armand-Frappier 531 boul.des Prairies Laval Qubec Canada Effluents and Wastewaters Aquatic Contaminants Research Division Water Science and Technology Environment Canada867 Lakeshore Road BurlingtonOntario Canada

Municipal effluents are known to impede the immune system of aquatic organisms. The purpose of this studywas to examine the immunotoxicity of urbanwastewaters before and after 6 treatment processes from 12 cities toward trout leucocytes. Freshly prepared trout leucocyteswere exposed to increasing concentrations of solid phase （C18） extracts ofwastewaters for24 hr at 15°C. Immunocompetencewasdetermined by following changes in leucocyte viability and the proportion of cells able to ingest at least one （immunoactivity） and at least three （immunoefficiency） fluorescent beads. The influentswere treated by sixdifferent treatment strategies consisting of facultative aerated lagoons, activated sludge, biological aerated filter, biological nutrient removal, chemically-assisted physical treatment and trickling filter/solid contact. Water quality parameters of thewastewaters revealed that the plants effectively removed total suspended solids and reduced the chemical oxygendemand. The results revealed that the effluents＇ immunotoxic propertieswere generally more influenced by the properties of the untreatedwastewaters than by the treatment processes. About half of the incoming influentsdecreased leucocyte viabilitywhile4 treatment plantswere able to reduce toxicity. The influents readily increased phagocytosis activity for 8/12 influentswhile itwasdecreased in4/12 influents. This increasewas abolished for4/12 of the effluents using treatments involving biological and oxidative processes. In conclusion, municipal effluents have the potential to alter the immune system in fish and more researchwill be needed to improve the treatments ofwastewaters to better protect the quality of the aquatic environment.

关键词： municipal effluents fish leucocytes viability phagocytosis

Analysis of Chaotic Dynamics in a Two-Dimensional Sine Square Map

在线全文

学校读者我要写书评

暂无评论

Chinese Physics Letters 2010年第2期27卷 33-36页

作者：徐杰隆克平 fournier-PRUNARET Daniele TAHA Abdel-Kaddous CHARGE Pascal School of Communication and Information Engineering University of Electronic Science and Technology of China Chengdu 611731 LATTIS INSA Toulouse University 135 avenue de Rangueil 31077 Toulouse 4 France

We study an N-dimensional system based upon a sine map, which is related to the simplified model of an opto-electronic system. The system behavior is analyzed with the tools of nonlinear dynamics （bifurcations in the parameter plane, critical manifolds, basins of attraction, chaotic attractors）. Our study relies on a two-dimensional system （N=2）. It is interesting that this system shows the existence of bounded chaotic orbits, which can be considered for secure transmissions.

关键词： Statistical physics and nonlinear systems