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Artificial intelligence for early detection of pancreatic adenocarcinoma: The future is promising

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World Journal of Gastroenterology 2021年第13期27卷 1283-1295页

作者： Antonio mendoza Ladd David L Diehl Department of Internal Medicine Division of GastroenterologyTexas Tech University Health Sciences Center El PasoEl PasoTX 79905United States Department of Gastroenterology and Nutrition Geisinger Medical CenterDanvillePA 17822United States

Pancreatic ductal adenocarcinoma(PDAC) is a worldwide public health concern. Despite extensive research efforts toward improving diagnosis and treatment, the 5-year survival rate at best is approximately 15%. This dismal figure can be attributed to a variety of factors including lack of adequate screening methods, late symptom onset, and treatment resistance. Pancreatic ductal adenocarcinoma remains a grim diagnosis with a high mortality rate and a significant psychological burden for patients and their families. In recent years artificial intelligence(AI) has permeated the medical field at an accelerated pace, bringing potential new tools that carry the promise of improving diagnosis and treatment of a variety of diseases. In this review we will summarize the landscape of AI in diagnosis and treatment of PDAC.

关键词： Pancreatic adenocarcinoma Artificial intelligence Neural network Future perspectives Early diagnosis Improved performance

Augmented reality for supporting geo-spatial planning:An open access review

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Visual Informatics 2023年第4期7卷 1-12页

作者： Reint Jansen Frida Ruiz mendoza William Hurst Laboratory of Geo-Information Science and Remote Sensing Wageningen University&ResearchThe Netherlands Information Technology Group Wageningen University&ResearchThe Netherlands

Augmented reality is gaining traction across many *** of these is participation within geo-spatial planning *** interactive and three-dimensional nature of augmented reality is suitably placed to cater for a higher quality of communication and information exchange in planning ***,this research provides an overview of the use of AR in planning processes,specifically regarding the participation aspect,through an open-access systematic literature review,for which the investigation identifies 35 articles concerning the current state-of-the-art of augmented reality in *** indicate the rather limited use of augmented reality in the overall planning process due to technical ***,it shows to be a useful technology where it allows for higher user engagement and a clearer understanding among users in planning ***,in participation,the technology offers a motivational solution and creates an overall higher acceptance and awareness of the plan,making the participants more engaged and represented in the planning process.

关键词： Augmented reality Systematic literature review Participation Planning Geo-visualization

Exploring hemp seed hull biomass for an integrated C-5 biorefinery:Xylose and activated carbon

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Journal of Bioresources and Bioproducts 2024年第3期9卷 310-321页

作者： Sreesha Malayil Luke Loughran Frederik mendoza Ulken Jagannadh Satyavolu Conn Center for Renewable Energy Research University of LouisvilleKentucky 40292United States Bioproducts LLC LouisvilleKentucky 40206United States RTI International Research Triangle ParkNC 27709United States

Large quantities of hemp hulls can be completely utilized for creation of value-added products (cost effective biofuels and biochemicals) through a biorefinery approach. A sustainable approach in making xylose, a low calorie sweetener and high surface area activated carbons (AC) for super capacitors, attracts interest. The AC when leveraged as a co-product from biorefinery process makes it more cost effective and, in this paper, we discuss the production of xylose and AC from hemp seed hull with methane sulphonic acid (MSA) hydrolysis. Xylose recovery with MSA hydrolysis was 25.15 g/L when compared to the traditional sulphuric acid (SA) hydrolysis of 19.96 g/L at the same acid loading of 1.8 %. The scanning electron microscope (SEM) images and Fourier transform infrared (FT-IR) spectra indicate partial delignification along with hemicellulose hydrolysis responsible for high xylose recovery. Post hydrolysis fibers were KOH activated and carbonized to make AC. The MSA hydrolyzed and KOH activated fiber produced pure, fluffier and finer particle AC with a drastic increase in surface area 1 452 m2/g when compared to SA hydrolyzed of 977 m2/g. These results indicate the potential of MSA in dilute acid hydrolysis of biomass for xylose recovery and production of high surface area activated carbon. From a production standpoint this can lead to increased use of sustainable low-cost agricultural biomass for making high surface area AC as components in supercapacitors.

关键词： Xylose C-5 biorefinery Methane sulphonic acid Delignification Activated carbon Dilute acid hydrolysis

Reconstructing the Memory of the Wounded Social Body:A Philosophical Theological Reflection from the Search for Missing Persons in Mexico

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Journal of Foreign Languages and Cultures 2021年第2期5卷 33-38,156页

作者： Carlos mendoza-Alvarez Boston College

This essay analyzes the phenomenon of clandestine graves of missing persons in Mexico as a social,political,and philosophical problem,where theological clues are *** the contributions of decolonial thought this reflection seeks to think the absence and,within it,to think the emergence of an alternative world promoted by the just people of history with the resistances they create to live the present with dignity and hope.

关键词： missing people resistances survivors messianic times

New reference trajectory optimization algorithm for a flight management system inspired in beam search

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Chinese Journal of Aeronautics 2017年第4期30卷 1459-1472页

作者： Alejandro MURRIETA-mendoza Bruce BEUZE Laurane TERNISIEN Ruxandra Mihaela BOTEZ Research Laboratory in Active Control Avionics and Aeroservoelasticity (LARCASE) Universitd du Quebec (Ecole deTechnologie Superieure - ETS) Montreal H3C 1K3 Canada

With the objective of reducing the flight cost and the amount of polluting emissions released in the atmosphere, a new optimization algorithm considering the climb, cruise and descent phases is presented for the reference vertical flight trajectory. The selection of the reference vertical navigation speeds and altitudes was solved as a discrete combinatory problem by means of a graphtree passing through nodes using the beam search optimization technique. To achieve a compromise between the execution time and the algorithm＇s ability to find the global optimal solution, a heuristic methodology introducing a parameter called ‘‘optimism coefficient was used in order to estimate the trajectory＇s flight cost at every node. The optimal trajectory cost obtained with the developed algorithm was compared with the cost of the optimal trajectory provided by a commercial flight management system（FMS）. The global optimal solution was validated against an exhaustive search algorithm（ESA）, other than the proposed algorithm. The developed algorithm takes into account weather effects, step climbs during cruise and air traffic management constraints such as constant altitude segments, constant cruise Mach, and a pre-defined reference lateral navigation route. The aircraft fuel burn was computed using a numerical performance model which was created and validated using flight test experimental data.

关键词： Beam search Commercial aircraft Flight time Flight management system Fuel burn FMS Trajectory optimization

Introducing System Identification Strategy into Model Predictive Control

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Journal of Systems Science & Complexity 2020年第5期33卷 1402-1421页

作者： WANG Jianhong RICARDO A.Ramirez-mendoza JORGE de J Lozoya Santos School of Electronic Engineering and Automation Jiangri University of Science and TechnologyGanzhou343000China School of Engineering and Sciences Tecnologico de MonterreyMonterreyAve.Eugenio Garza Sada 2501MonterreyN.L.64849Merico

As system identification theory and model predictive control are belonged to two different research fields separately,so one gap exists between these two *** alleviate this gap between them,one new idea proposed in this paper is to introduce system identification theory into model predictive *** the most important element in model predictive control is the prediction of the output value for a nonlinear system,then the problem of deriving the prediction of the output value can be achieved by system identification *** specifically,a Bayesian approach is applied for the nonparametric estimation by modeling the prediction as realizations of zero mean random *** comparing this kind of prediction corresponding to this Bayesian approach and the former direct weight optimization identification for nonlinear system,the authors see that if the unknown weights are chosen appropriately,these two approaches are equivalent to each *** on the obtained prediction of the output value,the authors substitute this prediction of the output value into one cost function of model predictive control,and then a quadratic programming problem with inequality constraints is *** to solve this quadratic programming problem,a detailed process about how to derive its dual form is *** the dual problem has a simple constraint set,it is amenable to the use of the common Gauss-Seidel algorithm,whose convergence can be shown ***,one simulation example confirms the proposed theoretical results.

关键词： Equivalence model predictive control nonparametric estimation system identification

An Architecture for Software Engineering Gamification

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Tsinghua Science and Technology 2020年第6期25卷 776-797页

作者： Oscar Pedreira Felix Garcia Mario Piattini Alejandro Cortinas Ana Cerdeira-pena the Universidade da Coruna Centro de Investigacion CITICLaboratorio de Bases de DatosFacultade de InformaticaElvinaA Coruna15071Spain the Universidad de Castilla-La Mancha Grupo AlarcosEscuela Superior de InformaticaPaseo de la Universidad4Ciudad Real13071Spain.

Gamification has been applied in software engineering to improve quality and results by increasing people’s motivation and engagement.A systematic mapping has identified research gaps in the field,one of them being the difficulty of creating an integrated gamified environment comprising all the tools of an organization,since most existing gamified tools are custom developments or *** this paper,we propose a gamification software architecture that allows us to transform the work environment of a software organization into an integrated gamified environment,i.e.,the organization can maintain its tools,and the rewards obtained by the users for their actions in different tools will mount *** developed a gamification engine based on our proposal,and we carried out a case study in which we applied it in a real software development *** case study shows that the gamification engine has allowed the company to create a gamified workplace by integrating custom-developed tools and off-the-shelf tools such as Redmine,TestLink,or JUnit,with the gamification *** main advantages can be highlighted:(i)our solution allows the organization to maintain its current tools,and(ii)the rewards for actions in any tool accumulate in a centralized gamified environment.

关键词： gamification software engineering gamification architecture gamification engine

Small molecules to prevent the neurodegeneration caused by α-synuclein aggregation

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Neural Regeneration Research 2020年第12期15卷 2260-2261页

作者： Samuel pena-Díaz Jordi Pujols Salvador Ventura Institut de Biotecnologia i Biomedicina Departament de Bioquímica i Biologia MolecularUniversitat Autònoma de BarcelonaBellaterraSpain

Parkinson’s disease (PD) is a neurodegenerative disorder belonging to a group of human pathologies known as synucleinopathies,which includes multiple system atrophy or dementia with Lewy bodies (Spillantini et al.,1998).These diseases share a common neuropathological feature,the presence ofα-synuclein (α-Syn) deposits,although they differ in the cellular and anatomical compartment in whichα-Syn inclusions *** affects more than 1% of people over 60 years of age,thus being the second most prevalent neurodegenerative disease in the world and the most common synucleinopathy.

关键词： al. diseases atrophy

Three-Dimensional Angular Momentum Projected Relativistic Point-Coupling Approach for Low-Lying Excited States in ^24Mg

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Chinese Physics Letters 2008年第10期25卷 3609-3612页

作者：尧江明孟杰 D. pena Arteaga P. Ring School of Physics and State Key Laboratory of Nuclear Physics and Technology Peking University Beijing 100871 Physik-Department der Technischen Universitat Munchen D-85748 Garching Germany Institute of Theoretical Physics Chinese Academy of Sciences Beijing 100190 Center of Theoretical Nuclear Physics National Laboratory of Heavy Ion Accelerator Lanzhou 730000

A tull three-dimensional angular momentum projection on top ot a triaxial relativistic mean-fieid calculation is implemented for the first time. The underlying Lagrangian is a point coupling model and pairing correlations are taken into account by a monopole force. This method is applied for the low-lying excited states in ^24Mg. Good agreement with the experimental data is found for the ground state properties. A minimum in the potential energy surface for the 22^＋ state, with β≈ 0.55,7 γ≈ 10^o, is used as the basis to investigate the rotational energy spectrum as well as the corresponding B（E2） transition probabilities as compared to the available data.

关键词： the power-law exponents precipitation durative abrupt precipitation change