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Prematurity and the burden of influenza and respiratory syncytial virus disease

世界儿科杂志:英文版 2016年第1期12卷 8-18页

作者： bernhard resch Stefan Kurath-Koller Monika Eibisberger Werner Zenz Research Unit for Neonatal Infectious Diseases and Epidemiology Division of NeonatologyDepartment of Pediatrics and Adolescent MedicineMedical University of GrazAustria Research Unit for Neonatal Infectious Diseases and Epidemiology Medical University of GrazAustria Research Unit for Infectious Diseases and Vaccinology Division of General PediatricsDepartment of Pediatrics and Adolescent MedicineMedical University of GrazAustria

Background:Respiratory morbidity of former preterm infants and especially those with bronchopulmonary dysplasia(BPD)is high during infancy and early *** sources:We performed a review based on a literature search including EMBASE,MEDLINE,and CINAHL databases to identify all relevant papers published in the English and German literature on influenza and respiratory syncytial virus infection associated with preterm infant,prematurity,and BPD between 1980 and ***:Recurrent respiratory symptoms remain common at preschool age,school age and even into young *** viral respiratory tract infections due to different pathogens cause significant morbidity and necessitate rehospitalizations during the fi rst years of *** uenza virus infection plays a minor role compared to respiratory syncytial virus(RSV)associated respiratory tract infection during infancy and early ***,particular morbidity to both viruses is ***:The particular burden of both viral diseases in preterm infants is dominated by RSV and its associated rehospitalizations during the fi rst two years of *** measures include vaccination against influenza virus of family members and caregivers and active immunization starting at the age of 6 months,and monthly injections of palivizumab during the cold season to avoid severe RSV disease and its sequelae.

关键词： bronchopulmonary dysplasia infl uenza preterm infant respiratory infectious disease respiratory syncytial virus

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Burden of respiratory syncytial virus infection in young children

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World Journal of Clinical Pediatrics 2012年第3期1卷 8-12页

作者： bernhard resch Research Unit for Neonatal Infectious Diseases and Epidemiology Division of Neonatology Department of Paediatrics Medical University of Graz

Respiratory syncytial virus(RSV) is the most frequent and important cause of lower respiratory tract infection in infants and children. It is a seasonal virus, with peak rates of infection occurring annually in the cold season in temperate climates, and in the rainy season, as temperatures fall, in tropical climates. High risk groups for severe RSV disease include infants below six mo of age, premature infants with or without chronic lung disease, infants with hemodynamically significant congenital heart disease, infants with immunodeficiency or cystic fibrosis, and infants with neuromuscular diseases. Mortality rates associated with RSV infection are generally low in previous healthy infants(below 1%), but increase significantly in children with underlying chronic conditions and comorbidities. Following early RSV lower respiratory tract infection, some patients experience recurrent episodes of wheezing mimicking early childhood asthma with persistence of lung function abnormalities until adolescence. There is currently no RSV vaccine available, but promising candidate vaccines are in development. Palivizumab, a monoclonal RSV antibody that is the only tool for immunoprophylaxis in high-riskinfants, lowers the burden of RSV infection in certain carefully selected patient groups.

关键词： Children Epidemiology Infant Palivizumab Respiratory syncytial virus Respiratory tract infection Risk factors Vaccine

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Pervasive geo-security - a lightweight triple-A approach to securing distributed geo-service infrastructures

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International Journal of Digital Earth 2014年第5期7卷 373-390页

作者： Bernd resch bernhard Schulz Manfred Mittlboeck Thomas Heistracher Research Studio iSPACE Research Studios AustriaSalzburgAustria SENSEable City Laboratory Massachusetts Institute of TechnologyBostonMAUSA Department of Information Technology and Systems Management University of Applied SciencesSalzburgAustria

Security has recently become a major concern in distributed geo-infrastructures for spatial data ***,a lightweight approach for securing distributed low-power environments such as geo-sensor networks is *** first part of this article presents a survey of current security mechanisms for authentication and *** on this survey,a lightweight and scalable token-based security infrastructure was developed,which is tailored for use in distributed geo-web service *** developed security framework comprises dedicated components for authentication,rule-based authorisation and optimised storage and administration of access *** validation purposes,a prototypical implementation of the approach has been created.

关键词： pervasive security distributed geo-service infrastructures triple-A geo-authorisation standardised sensor networks service protection Geographic Information Systems(GIS) geoinformatics spatial data infrastructure Digital Earth Digital Earth Architecture

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