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soil resilience assessment using soil profile descriptions and Analytic Hierarchy Process in Mediterranean mountains considering diverse fire occurrences

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Journal of Mountain science 2024年第8期21卷 2517-2532页

作者： Jesús RODRIGO-COMINO Departamento de Análisis Geográfico Regional y Geografía Física Facultad de Filosofía y LetrasCampus Universitario de CartujaUniversidad de GranadaGranada 18071Spain

Wildfires are complex natural phenomena that exert significant impacts on landscapes,societies,and *** the concept of resilience is crucial in mitigating its possible negative impacts,as it involves preparing for,responding to,and recovering from *** research aims to demonstrate the utility of in situ soil profile description in assessing land use resilience using an Analytic Hierarchy Process(AHP)through an expert panel *** study examines a catchment located in the Balearic Islands,considering two fire occurrences(once and twice),comparing abandoned agricultural terraces and natural *** results demonstrated that the priority ranking of variables to assess soil profile resilience against wildfires,determined by a panel of 10 experts,identified horizon depth(25.1%),slope inclination(21.5%),and hydrological connectivity(16.6%)as the most crucial *** variables,such as number and size of roots,structure of pedal soil material,size class structure,and rock fragments,also contributed to resilience but to a lesser extent,with scores ranging from 5.7%to 9.6%.Analyzing the priorities established by the experts using AHP,the results showed that the least resilient soil horizon was H1 of the control hillslope,especially under high and low connectivity processes,which aligned with the loss of superficial soil horizons after one and two *** showed greater changes in resilience after occurring wildfires compared to terraces,with the most significant alterations occurring after the second wildfire *** study addresses a significant knowledge gap in the field by highlighting the interconnectedness of wildfires,resilience,and land use,providing insights into land management strategies for wildfire-prone regions.

关键词： soil profiles soil geography Wildfires AHP Land management Expert panel survey

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Pressure-responsive pH-triggered layer-by-layer coating of paclitaxel-eluting balloon catheters for instant high-dose drug delivery for percutaneous coronary artery intervention

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Nano Research 2024年第10期17卷 9141-9151页

作者： Jeong Yu Lee shonit Nair sharma sung-Yu Hong Young-Guk ko Yangsoo Jang Minjae Do Michael Christopher stark Qiwen Peng Benjamin Allen Mossburg Bo Chan seo Yuhan Lee Department of Materials science and Engineering Korea Advanced Institute of Science and TechnologyDaejeon 305-701Republic of Korea Department of Anesthesiology Perioperativeand Pain MedicineCenter for Accelerated Medical Innovation&Center for NanomedicineBrigham and Women’s HospitalHarvard Medical SchoolBostonMA 02115USA Department of Biological Engineering Massachusetts Institute of TechnologyCambridgeMA 02139USA Cardiovascular Product Evaluation Center Yonsei University College of MedicineSeoul 120-752Republic of Korea Division of Cardiology Department of Internal MedicineSeverance Cardiovascular HospitalYonsei University College of MedicineSeoul 120-752Republic of Korea

Cardiovascular diseases remain the leading cause of mortality worldwide,with percutaneous coronary interventions(PCI)using drug-eluting stents(DEs)as the standard treatment for coronary artery *** advancements in DEs technology,challenges such as restenosis and stent thrombosis still necessitate further interventions and carry considerable risks,highlighting an urgent need for a novel therapeutic approach with lower restenosis rates and reduced reintervention *** balloons(DEBs)coated with anti-proliferative agents offer a novel method of local drug delivery for reducing restenosis by directly administering drugs to the lesion ***,efficient delivery of drugs within the brief procedural window while minimizing drug loss during maneuvering to the target site remains a ***,we developed a pressure-responsive and pH-triggered,paclitaxel(PTX)coated DEB catheter for rapid and high-dose delivery of paclitaxel to the lesion sites,overcoming the limitations of drug dispersion and inefficiencies associated with conventional *** the charge reversion of albumin around its isoelectric point,paclitaxel-loaded human serum albumin nanoparticles(PTX-HsA-NPs)and heparin were coated using a layer-by-layer deposition method at pH *** exposure to physiological pH(i.e.,7.4),the coating is rapidly released from the balloon *** with a protective shellac coating,the DEB achieved controlled release of high-dose paclitaxel to the arterial tissue in vivo(up to 400μg per gram tissue),exceeding current DEBs in the *** results suggest the pH-responsive,multi-layer coated DEB’s potential for superior procedural outcomes,addressing a critical unmet need in PCI.

关键词： drug-eluting balloon layer-by-layer coating coronary artery disease paclitaxel

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Litterfall production modeling based on climatic variables and nutrient return from stands of Eucalyptus grandis Hill ex Maiden and Pinus taeda L.

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Journal of Forestry Research 2024年第5期35卷 26-36页

作者： Andrés Baietto Andrés Hirigoyen Jorge Hernández Amabelia del Pino Forest Department Faculty of AgronomyUniversity of the Republic12900 MontevideoUruguay National Research Program of Forest Production National Agriculture Research InstituteINIA97000 TacuarembóUruguay soil and Water Department Faculty of AgronomyUniversity of the Republic12900 MontevideoUruguay

Native grasslands in the Pampas of south America are increasingly being replaced by Eucalyptus and Pinus *** short rotation regimes used for the stands require high nutrient levels,with litterfall being a major source of nutrient *** model the litterfall production using climatic variables and assess the nutrient return in 14-year-old Eucalyptus grandis and Pinus taeda stands,we measured litter production over 2 years,using conical litter traps,and monitored climatic *** temperature,accumulated precipitation,and mean maximum vapor pres-sure deficit at the seasonal level influenced litterfall produc-tion by ***;seasonal accumulated precipitation and mean maximum temperature affected litterfall by *** regression tree modeling based on these climatic vari-ables had great accuracy and predictive power for ***(N=33;MAE(mean absolute error)=0.65;RMsE(root mean square error)=0.91;R^(2)=0.71)and ***(N=108;MAE=1.50;RMsE=1.59;R^(2)=0.72).The nutrient return followed a similar pattern to litterfall deposition,as well as the order of importance of macronutrients(***:Ca>N>K>Mg>P;***:N>Ca>K>Mg>P)and micronutrients(*** and ***:Mn>Fe>Zn>Cu)in both *** study constitutes a first approximation of factors that affect litterfall and nutrient return in these systems.

关键词： Afforestation Litterfall Nutrient recycling Climate modeling Myrtaceae Pinaceae

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Cross-method Analysis of Corotation Radii Data set for spiral Galaxies

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Research in Astronomy and Astrophysics 2024年第7期24卷 95-110页

作者： V.s.kostiuk A.A.Marchuk A.s.Gusev sternberg Astronomical Institute Lomonosov Moscow State UniversityUniversitetsky pr.13119234 MoscowRussia Central(Pulkovo)Astronomical Observatory Russian Academy of SciencesPulkovskoye chaussee 65/1196140 St.PetersburgRussia saint Petersburg state University Universitetsky pr.28198504 St.PetersburgRussia

A corotation radius is a key characteristic of disk galaxies that is essential to determine the angular speed of the spiral structureΩ_p,and therefore understand its *** the literature,there are plenty of methods to estimate this value,but do these measurements have any consistency?In this work,we collected a data set of corotation radius measurements for 547 galaxies,300 of which had at least two *** initial analysis reveals that most objects have rather inconsistent corotation radius ***,a significant fraction of galactic disks is distinguished by a large error coverage and almost uniform distribution of *** findings do not have any relation to spiral type,Hubble classification,or presence of a *** other reasons,obtained results could be explained by the transient nature of spirals in a considerable part of *** have made our collected data sample publicly available,and have demonstrated on one example how it could be useful for future research by investigating a winding time value for a sample of galaxies with possible multiple spiral arm patterns.

关键词： galaxies fundamental parameters-galaxies kinematics and dynamics-galaxies structure

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Current state-of-the-art review of footwear–ground friction

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Friction 2024年第10期12卷 2188-2204页

作者： David REBENDA Tomáš sÁHA Footwear Research Centre University InstituteTomas Bata University in ZlinZlin 76001Czech Republic Faculty of Mechanical Engineering Brno University of TechnologyBron 61600Czech Republic

The most important role of footwear is to ensure safe,functional walking,and foot *** the proper functionality of not only the work shoes,the anti-slip behavior of the shoe under various conditions and environments plays an important role in the prevention of slips,trips,falls,and consequent *** article is intended to review the current understanding of the frictional mechanisms between shoe outsoles and various counterfaces that impact the evaluation of outsole *** research focuses on the mechanisms driving outsole friction on different ground surfaces or the definition and description of parameters that influence outsole ***,the review discusses the effect of various surface contaminants on footwear ***,challenges and outlooks in the field of footwear outsoles are briefly mentioned.

关键词： shoe outsole composite slipperiness coefficient of friction(COF) adhesion safe walk

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Endoscopic treatment of biliopancreatic pathology in patients with Whipple's pancreaticoduodenectomy surgical variants: Lessons learned from single-balloon enteroscopy-assisted ERCP

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Hepatobiliary & Pancreatic Diseases International 2024年第5期23卷 509-514页

作者： Rodrigo Garcés-Durán Laurent Monino Pierre H Deprez Hubert Piessevaux Tom G Moreels Department of Gastroenterology and Hepatology Universitécatholique de LouvainCliniques Universitaires Saint-LucAvenue Hippocrates 101200 BrusselsBelgium

Background: Endoscopic treatment of biliopancreatic pathology is challenging due to surgically altered anatomy after Whipple's pancreaticoduodenectomy. This study aimed to evaluate the feasibility and safety of single-balloon enteroscopy-assisted endoscopic retrograde cholangiopancreatography(sBE-ERCP) to treat biliopancreatic pathology in patients with Whipple's pancreaticoduodenectomy surgical variants. Methods: We retrospectively analyzed 106 sBE-ERCP procedures in 46 patients with Whipple's variants. Technical and clinical success rates and adverse events were evaluated. Results: Biliary sBE-ERCP was performed in 34 patients and pancreatic sBE-ERCP in 17, including 5 with both indications. From a total of 106 sBE-ERCP procedures, 76 were biliary indication with technical success rate of 68/76(90%) procedures and clinical success rate of 30/34(88%) patients. Mild adverse event rate was 8/76(11%), without serious adverse events. From a total of 106 sBE-ERCP procedures, 30 were pancreatic indication with technical success rate of 24/30(80%) procedures( P = 0.194 vs. biliary sBEERCP) and clinical success rate of 11/17(65%) patients( P = 0.016 vs. biliary sBE-ERCP). Mild adverse event rate was 6/30(20%)( P = 0.194 vs. biliary sBE-ERCP), without serious adverse events. After sBE-ERCP failure, endoscopic ultrasound-guided drainage, percutaneous drainage and redo surgery were alternative therapeutic options. Conclusions: Biliopancreatic pathology after Whipple's pancreaticoduodenectomy variants can be treated using sBE-ERCP without serious adverse events. Technical and clinical success rates are high for biliary indications, whereas clinical success rate of pancreatic indications is significantly lower. sBE-ERCP can be considered as first-line treatment option in this patient group with surgically altered anatomy.

关键词： Enteroscopy Endoscopic retrograde cholangiopancreatography Pancreaticoduodenectomy surgically altered anatomy Whipple’s procedure

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Dynamic and electrical responses of a curved sandwich beam with glass reinforced laminate layers and a pliable core in the presence of a piezoelectric layer under low-velocity impact

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Applied Mathematics and Mechanics(English Edition) 2024年第1期45卷 155-178页

作者： N.sHAHVEIsI s.FELI Department of Mechanical Engineering Razi UniversityKermanshah ***Iran

The dynamic responses and generated voltage in a curved sandwich beam with glass reinforced laminate(GRL)layers and a pliable core in the presence of a piezoelectric layer under low-velocity impact(LVI)are *** current study aims to carry out a dynamic analysis on the sandwich beam when the impactor hits the top face sheet with an initial *** the layer analysis,the high-order shear deformation theory(HsDT)and Frostig's second model for the displacement fields of the core layer are *** classical non-adhesive elastic contact theory and Hunter's principle are used to calculate the dynamic responses in terms of *** order to validate the analytical method,the outcomes of the current investigation are compared with those gained by the experimental tests carried out by other researchers for a rectangular composite plate subject to the *** element(FE)simulations are conducted by means of the ABAQUs *** effects of the parameters such as foam modulus,layer material,fiber angle,impactor mass,and its velocity on the generated voltage are reviewed.

关键词： analytical model piezoelectric layer curved sandwich beam glass reinforced laminate(GRL) pliable core low-velocity impact(LVI) classical non-adhesive elastic contact theory

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Emerging structures and dynamic mechanisms ofγ-secretase for Alzheimer’s disease

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Neural Regeneration Research 2025年第1期20卷 174-180页

作者： Yinglong Miao Michael s.Wolfe Computational Medicine Program and Department of Pharmacology University of North Carolina–Chapel HillChapel HillNCUSA Department of Medicinal Chemistry University of KansasLawrenceKSUSA

γ-secretase,called“the proteasome of the membrane,”is a membrane-embedded protease complex that cleaves 150+peptide substrates with central roles in biology and medicine,including amyloid precursor protein and the Notch family of cell-surface *** inγ-secretase and amyloid precursor protein lead to early-onset familial Alzheimer’s disease.γ-secretase has thus served as a critical drug target for treating familial Alzheimer’s disease and the more common late-onset Alzheimer’s disease as ***,critical gaps remain in understanding the mechanisms of processive proteolysis of substrates,the effects of familial Alzheimer’s disease mutations,and allosteric modulation of substrate cleavage byγ-*** this review,we focus on recent studies of structural dynamic mechanisms ofγ-*** mechanisms,including the“Fit-stay-Trim,”“sliding-Unwinding,”and“Tilting-Unwinding,”have been proposed for substrate proteolysis of amyloid precursor protein byγ-secretase based on all-atom molecular dynamics *** an incorrect registry of the Notch1 substrate was identified in the cryo-electron microscopy structure of Notch1-boundγ-secretase,molecular dynamics simulations on a resolved model of Notch1-boundγ-secretase that was reconstructed using the amyloid precursor protein-boundγ-secretase as a template successfully capturedγ-secretase activation for proper cleavages of both wildtype and mutant Notch,being consistent with biochemical experimental *** approach could be potentially applied to decipher the processing mechanisms of various substrates byγ-*** addition,controversy over the effects of familial Alzheimer’s disease mutations,particularly the issue of whether they stabilize or destabilizeγ-secretase-substrate complexes,is ***,an outlook is provided for future studies ofγ-secretase,including pathways of substrate binding and product release,effects of modulators on familial Alzheimer’s disease mutations

关键词： Alzheimer’s disease amyloid precursor protein cryo-EM structures drug design intramembrane proteolysis molecular dynamics Notch

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MXenes for Bioinspired soft Actuators:Advancements in Angle-Independent structural Colors and Beyond

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Nano-Micro Letters 2024年第8期16卷 18-34页

作者： siavash Iravani Rajender s.Varma Independent Researcher W Nazar STBoostan AveIsfahanIran Centre of Excellence for Research in sustainable Chemistry Department of ChemistryFederal University of São CarlosSão CarlosSP 13565‑905Brazil

soft actuators have garnered substantial attention in current years in view of their potential appliances in diverse domains like robotics,biomedical devices,and biomimetic *** actuators mimic the natural movements of living organisms,aiming to attain enhanced flexibility,adaptability,and *** the other hand,angle-independent structural color has been achieved through innovative design strategies and engineering *** carefully controlling the size,shape,and arrangement of nanostructures,researchers have been able to create materials exhibiting consistent colors regardless of the viewing *** promising class of materials that holds great potential for bioinspired soft actuators is MXenes in view of their exceptional mechanical,electrical,and optical *** integration of MXenes for bioinspired soft actuators with angle-independent structural color offers exciting *** material compatibility issues,improving color reproducibility,scalability,durability,power supply efficiency,and cost-effectiveness will play vital roles in advancing these *** perspective appraises the development of bioinspired MXene-centered soft actuators with angleindependent structural color in soft robotics.

关键词： MXenes MXene-based composites Bioinspired soft robotics Angle-independent structural color

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The emerging role of exercise as a cancer treatment

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Journal of sport and Health science 2024年第4期13卷 443-444页

作者： Kerry s.Courneya Faculty of Kinesiology Sportand RecreationCollege of Health SciencesUniversity of AlbertaEdmontonAlbertaT6G 2H9Canada

Over the past few decades,exercise oncology has emerged as an important subfield within exercise *** that time,substantial progress has been made in understanding the role of exercise in people newly diagnosed with ca... 详细信息

关键词： cancer treatment exercise

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