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Cancer Communications 2023年第8期43卷 956-959页

作者： Megha Bhardwaj Ben Schotker bernd holleczek Hermann Brenner Division of Clinical Epidemiology and Aging Research German Cancer Research Center(DKFZ)HeidelbergGermany Division of Preventive Oncology German Cancer Research Center(DKFZ)and National Center for Tumor Diseases(NCT)HeidelbergGermany German Cancer Consortium(DKTK) German Cancer Research Center(DKFZ)HeidelbergGermany Network Aging Research University of HeidelbergHeidelbergGermany Saarland Cancer Registry SaarbrückenGermany

Dear Editor,Lung cancer(LC)is the leading cause of cancer mortality globally,accounting for more than 1.7 million deaths per year[1].There is consensus that LC screening needs to target those at high risk who are most likely to benefit from screening in order to maximize benefits and minimize potential harms.Given the key role of smoking in determining LC risk[2],most of the low-dose computed tomography(LDCT)screening trials have defined heavy smoking as an eligibility criterion for LC screening[3].Although LDCT screening has been effective in reducing LC mortality[4,5].

关键词： mortality likely globally

A serum microRNA signature for enhanced selection of people for lung cancer screening

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Cancer Communications 2022年第11期42卷 1222-1225页

作者： Haixin Yu Janhavi R.Raut Megha Bhardwaj Yan Zhang Evelin Sandner Ben Schöttker bernd holleczek Petra Schrotz-King Hermann Brenner Division of Clinical Epidemiology and Aging Research German Cancer Research Center(DKFZ)Heidelberg 69120Baden-WürttembergGermany Medical Faculty Heidelberg University of HeidelbergHeidelberg 69120Baden-WürttembergGermany Division of Preventive Oncology German Cancer Research Center(DKFZ)and National Center for Tumor Diseases(NCT)Heidelberg 69120Baden-WürttembergGermany German Cancer Consortium(DKTK) German Cancer Research Center(DKFZ)Heidelberg 69120Baden-WürttembergGermany Pneumology and Thoracic Oncology Robert-Bosch KrankenhausKlinik SchillerhoeheGerlingen 70839Baden-WürttembergGermany Network Aging Research University of HeidelbergBergheimer Straße 20Heidelberg 69115Baden-WürttembergGermany Saarland Cancer Registry Präsident-Baltz-Straße 5Saarbrucken 66119SaarlandGermany

Dear editor,Lung cancer(LC)is the leading cause of cancer-related mortality globally[1].Earlier detection by screening can substantially reduce LC mortality[2,3],but should be focused on those at highest risk[4].Risk stratification for LC screening,which is mostly based on smoking history[5],is far from perfect[6].Therefore,additional criteria to better define those at highest risk of LC are needed to enhance the efficiency and cost-effectiveness of LC screening.Besides risk prediction models incorporating classical LC risk factors[7].

关键词： mortality cancer signature

A Tropical View on Landau-Ginzburg Models

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Acta Mathematica Sinica,English Series 2024年第1期40卷 329-382页

作者： Michael CARL Max PUMPERLA bernd SIEBERT Alfred-Delp-Str.2 73430 AalenGermany IU Internationale Hochschule Juri-Gagarin-Ring 15299084 ErfurtGermany AnyscaleInc.2080 Addison St Ste 7BerkeleyCA 94704USA Department of Mathematics The Univ.of Texas at Austin2515 SpeedwayAustinTX 78712USA

This paper,largely written in 2009/2010,fits Landau-Ginzburg models into the mirror symmetry program pursued by the last author jointly with Mark Gross since 2001.This point of view transparently brings in tropical disks of Maslov index 2 via the notion of broken lines,previously introduced in two dimensions by Mark Gross in his study of mirror symmetry for P2.A ma jor insight is the equivalence of properness of the Landau-Ginzburg potential with smoothness of the anticanonical divisor on the mirror side.We obtain proper superpotentials which agree on an open part with those classically known for toric varieties.Examples include mirror LG models for non-singular and singular del Pezzo surfaces,Hirzebruch surfaces and some Fano threefolds.

关键词： Landau-Ginzburg model mirror symmetry tropical disk broken line wall structure scattering diagram Gross-Siebert program del Pezzo surface toric degeneration

Removal of endocrine disrupting chemicals from water through urethane functionalization of microfiltration membranes via electron beam irradiation

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Frontiers of Environmental Science & Engineering 2024年第4期18卷 61-74页

作者： Zahra Niavarani Daniel Breite Muhammad Yasir Vladimir Sedlarik Andrea Prager Nadja Schönherr bernd Abel Roger Gläser Agnes Schulze Leibniz Institute of Surface Engineering eV.(IOM) Permoserstrasse 1504318 LeipzigGermany Centre of Polymer Systems University InstituteTomas Bata University in ZlinTrida Tomase Bati 567876001 ZlinCzech Republic Institute of Chemical Technology Leipzig UniversityLinnestrasse 304103 LeipzigGermany

Polyethersulphone(PES)membranes modified with urethane functional groups were prepared through an interfacial reaction using electron beam irradiation.The removal of eight endocrine disrupting chemicals(EDCs)was studied using both pristine and functionalized PES membranes.The prepared membranes underwent characterization using several techniques,including attenuated total reflectance-Fourier transform infrared(ATR-FTIR)spectroscopy,scanning electron microscopy,contact angle analysis,and measurements of pure water flux.Furthermore,dynamic adsorption experiments were conducted to evaluate the adsorption mechanism of the prepared membrane toward the eight EDCs.The urethane functionalized membranes were hydrophilic(52°contact angle)and maintained a high permeate flux(26000 L/h m2 bar)throughout the filtration process.Dynamic adsorption results demonstrated that the introduction of urethane functional groups on the membranes significantly enhanced the removal efficiency of 17β-estradiol,estriol,bisphenol A,estrone,ethinylestradiol,and equilin.The adsorption loading of 17β-estradiol on the functionalized PES membrane was 6.7±0.7 mg/m^(2),exhibiting a 5-fold increase compared to the unmodified PES membrane.The membranes were successfully regenerated and reused for three adsorption cycles without experiencing any loss of adsorption capacity.

关键词： Surface functionalization Electron beam irradiation Microfiltration Endocrine disrupting chemicals

Primary carbohydrate metabolism genes participate in heat-stress memory at the shoot apical meristem of Arabidopsis thaliana

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Molecular Plant 2024年第4期17卷 676-676页

作者： Justyna Jadwiga Olas Federico Apelt Maria Grazia Annunziata Sheeba John Sarah Isabel Richard Saurabh Gupta Friedrich Kragler Salma Balazadeh bernd Mueller-Roeber 不详

(Molecular Plant 14,1508-1524,September 62021)After the original publication of the above article,attentive readers identified errors in Figure 4H that needed correction as follows.Figure 4H contained the erroneous labels“10 DAP(7 DAT),”which should have each read,“7 DAP(4 DAT).”To avoid any confusion and ensure consistency across our figures,we modified some of the Col-0 images in a corrected version of Figure 4H below to resemble the exact same Col-0 images as in Figure 1C.The details of the changes are as follows:rotation(Col-0 Primed,all timepoints;Col-0 Triggered,3 DAP and 5 DAP;Col-0 Primed/triggered,3 DAP and 5 DAP),replacement(Col-0 Triggered,7 DAP),and different cropping(Col-0 Primed/triggered,7 DAP).

关键词： Figure metabolism Prime

驶向绿色城市韧性的未来:绿色城市结构作为危机管理与韧性的支撑

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景观设计学（中英文） 2024年第1期12卷 4-8页

作者：伯尔德·南特维格德国魏玛包豪斯大学建筑与城市规划学院魏玛99423

在城市景观快速变化的背景之下,绿色城市结构的整合正成为应对气候变化和流动性问题带来的多重挑战的关键解决方案。本文提出了一种可持续城市发展的思路,强调在城市生活的各个方面融入绿色城市结构和更具环保意识的规划原则的必要性。... 详细信息

在城市景观快速变化的背景之下,绿色城市结构的整合正成为应对气候变化和流动性问题带来的多重挑战的关键解决方案。本文提出了一种可持续城市发展的思路,强调在城市生活的各个方面融入绿色城市结构和更具环保意识的规划原则的必要性。通过分析城市挑战和潜在危机的影响,本文呼吁政府机构、私营企业和地方社区之间的通力协作,以促进能够减轻生态脆弱性、增强绿色城市韧性的创新解决方案的提出。在绿色城市结构的视角下,本文着重论述了城市向更具可持续性、适应性和韧性,能够抵御未来不可预测风险的空间转型潜力。

关键词：绿色城市结构绿色城市韧性气候变化流动性危机管理可持续发展

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方法问题即宪法问题?

南大法学 2024年第3期 167-188页

作者： [德]伯恩·魏德士汪西兴(译) 不详北京大学法学院

二战后,法学方法论在德意志联邦共和国的法学教育中处于相当边缘的地位,关于法学方法史的讨论更为寥落,甚至成为禁忌。当代法律人掌握了很多方法论工具,却对这些方法在历史上的“法律政治”后果毫无所悉。德国极权时期(如纳粹)的沉痛教... 详细信息

二战后,法学方法论在德意志联邦共和国的法学教育中处于相当边缘的地位,关于法学方法史的讨论更为寥落,甚至成为禁忌。当代法律人掌握了很多方法论工具,却对这些方法在历史上的“法律政治”后果毫无所悉。德国极权时期(如纳粹)的沉痛教训不应简单归咎于法律实证主义,当时盛行的客观解释方法也应负很大的责任。法律的客观目的只是浪漫的虚构,法律文本的客观意义并不存在,故客观解释相当盲目,释法者可以借此将自己的主观意志或者“时代精神”注入法律。德国极权时期的法律人将当时主导性的意识形态注入法律,对法体系重新解释、整体改造,使法律沦为政治的婢女。需要强调的是,方法问题关乎宪法:法官受法律的拘束是民主法治国的内在要求。以解释之名行造法之实,法官自由选择方法来追求所欲的结果,法律在被法官适用之前根本不存在的“自由法”观念,等等,方法上的恣意违反了宪法所要求的民主、平等、权力分立与法治国原则,使得司法过程不具有可证伪性和可检验性。司法造法是必要的,法官法的法源地位应得到承认。但法官不能以客观解释的名义恣意造法,而应坚持方法论的诚实,为造法行为承担更高的论证义务:只有证实漏洞存在,或者在对立法目的进行历史考察,并证明当下的情事与价值确已变迁时,才可进行造法。造法的内容也要受到宪法的控制。

关键词：法学方法论客观解释民主法治国司法造法卡尔·拉伦茨

The tip of the iceberg?The underestimated potential of non-canonical beta-amyloids for Alzheimer's disease

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Neural Regeneration Research 2023年第12期18卷 2689-2690页

作者： Lukas Busch bernd Bufe Department of Informatics and Microsystems Technology University of Applied Sciences KaiserslauternZweibrückenGermany

Formation and deposition of amyloid-beta(Aβ) are considered one of the main drivers of Alzheimer's disease(AD). For more than 30 years, Aβ has challenged researchers through its complex physicochemical properties an... 详细信息

关键词： amyloid Alzheimer Aβ

从韧性城市大会到雄心城市峰会:韧性城市发展政策、行动与热点

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景观设计学（中英文） 2024年第1期12卷 9-25页

作者：陈娜雷卓君向辉彭瑾伯尔德·南特维格湖南大学建筑与规划学院长沙410082 丘陵地区城乡人居环境科学湖南省重点实验室长沙410082 德国慕尼黑工业大学管理学院慕尼黑803334 德国魏玛包豪斯大学建筑与城市规划学院魏玛99423

韧性城市大会(2010~2019年)和雄心城市峰会(2020年至今)是首个聚焦国际韧性城市研究与实践最新进展的年度全球论坛,持续推动了全球韧性城市的发展与合作。基于大会相关资料及文献,文章从政策、行动与热点视角梳理了十余年来韧性城市的... 详细信息

韧性城市大会(2010~2019年)和雄心城市峰会(2020年至今)是首个聚焦国际韧性城市研究与实践最新进展的年度全球论坛,持续推动了全球韧性城市的发展与合作。基于大会相关资料及文献,文章从政策、行动与热点视角梳理了十余年来韧性城市的发展进程,总结了韧性城市发展的前沿重点及最新动态。概括而言,全球韧性城市的发展经历了“全球承诺与框架确立-路径探索与行动-经验转化与效仿”三个阶段。基于多层次行动、多利益相关者合作和社区参与的韧性建设及融资是历届韧性城市大会的核心主题;坚持以地方政府为核心角色,兼顾社会、经济与环境三方面,进行多学科、跨领域的合作与创新是实现韧性与整体可持续发展的关键所在;面对数字化时代的新兴挑战与机遇,建设健康、安全的网络发展环境,从而有效提升网络韧性,是推动数字化时代下城市可持续发展的有力补充。文章最后探讨了韧性城市系列大会的经验与成果对中国韧性城市研究与实践的启示,建议针对中国国情与城市特点,推动吸收转化韧性行动经验,并积极实现各城市和地区韧性建设方案的本土化调整。

关键词：韧性城市雄心城市政策梳理行动路径热点趋势网络韧性

Model of an iron ore sinter plant with selective waste gas recirculation

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Carbon Resources Conversion 2022年第1期5卷 71-83页

作者： Johannes Niel bernd Weiss Walter Wukovits TU Wien Institute of ChemicalEnvironmental and Bioscience EngineeringGetreidemarkt 9/1661060 ViennaAustria Primetals Primetals Technologies Austria GmbHLinzAustria

The use of sinter influences hot metal production substantially and significantly affects an integrated steel mill’s total emissions. Sintering of iron ores is an enormousenergy-intensive and resources consuming process. Introducing a selective waste gas recirculation (SWGR) to the sintering process reduces the energy consumption,stack gas volume flow, and sulfur dioxide emissions of an iron sinter production. Simulating this complex process in flowsheet simulations of integrated iron andsteelworks is a fast and cost-effective opportunity to validate new operation settings. The implementation of a sinter plant in gPROMS ModelBuilder®characterizesthe sintering processes by three main sub-models. A burner model describes the gas combustion, a black-box model consider the main sintering processes, and a windbox model divides the total off-gas into a recycle gas and a stack gas. A specific temperature polynomial represents the temperature distribution across the wind boxesto allow detailed investigations on SWGR in complex flowsheet simulations. Implementing SWGR to the sintering process, the model shows a reduction of cokeconsumption, stack gas flow rate, and sulfur dioxide emissions by 11%, 27%, and 27%, respectively. In the SWGR scenario, the utilization rate of carbon monoxideincreases and less coke is consumed. The chlorine emissions of the sintering process differ with and without SWGR insignificantly.

关键词： dioxide monoxide consuming