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Assessing the effectiveness of quarantine measures during the COVID-19 pandemic in Chile using Bayesian structural time series models

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Infectious Disease Modelling 2022年第4期7卷 625-636页

作者： Claudia Barría-Sandoval Guillermo Ferreira bernardo Lagos Carola Montecino Bacigalupo Nursing School Faculty of Health and Social SciencesUniversidad de las AméricasConcepciònChile Faculty of Nursing Universidad de ConcepciònConcepciònChile Department of Statistics Universidad de ConcepciònConcepciònChile Applied Mathematics Group(GMA)Faculty of Sciences Universidad del BiobíoConcepciònChile Nursing School Faculty of Health and Social SciencesUniversidad de las AméricasSantiagoChile

Background:With the emergence of the COVID-19 pandemic,all existing health protocols were tested under the worst health crisis humanity has experienced since the Black Death in the 14th *** in Latin America have been the epicenter of the COVID-19 pandemic,with more than 1.5 million people *** health measures have included quarantines,border closures,social distancing,and mask use,among *** particular,Chile implemented total or partial quarantine measures depending on the number of infections in each region of the ***,it is necessary to study the effectiveness of these quarantines in relation to the public health measures implemented by government entities at the national ***:The main objective of this study is to analyze the effectiveness of national-and region-level quarantines in Chile during the pandemic based on information published by the Chilean Ministry of Health,and answers to the following question are sought:Were quarantine measures in Chile effective during the COVID-19 pandemic?Methods:The causal effect between the rates of COVID-19 infections and the population rates in Phase 1 and Phase 2 quarantines in the period from March 2020 to March 2021 in different regions of Chile were evaluated using intervention analyses obtained through Bayesian structural time series *** addition,the Kendall correlation coefficient obtained through the copula approach was used to evaluate the comovement between these ***:In 75%of the Chilean regions under study(12 regions out of a total of 16),an effective Phase 1 quarantine,which was implemented to control and reduce the number of cases of COVID-19 infection,was *** main regions that experienced a decrease in cases were those located in the north and center of *** Phase 2,the COVID-19 pandemic was effectively managed in 31%(5 out of 16)of the *** the southcentral and extreme southern regions of Chile,the effectiveness o

关键词： Comovement Bayesian time series models Novel coronavirus 2010 MSC 00e01 99-00

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Habitat-dependent breeding biology of the Blue Tit(Cyanistes caeruleus)across a continuous and heterogeneous Mediterranean woodland

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Avian Research 2023年第3期14卷 499-510页

作者： Jorge Garrido-Bautista Carmen Hernandez-Ruiz Jose Luis Ros-Santaella Eliana Pintus Nicola bernardo Mar Comas Gregorio Moreno-Rueda Department of Zoology Faculty of SciencesUniversity of Granada18071GranadaSpain Tecnologías y Servicios Agrarios S.A. S.M.E.M.P.(Tragsatec)06800BadajozSpain Department of Veterinary Sciences Faculty of AgrobiologyFood and Natural ResourcesCzech University of Life Sciences PragueKamýcka 12916500Prague 6-SuchdolCzech Republic Biological Station of Donana EBD-CSICAv.Americo Vespucio 2641092SevilleSpain Department of Biological Sciences Dartmouth College03755HanoverNHUSA

Mediterranean woodland environments are characterised by high spatial and temporal heterogeneity,which means the inhabiting species face a wide variety of selective *** may respond differently to habitat heterogeneity and so distinct eco-evolutionary scenarios may be responsible for the inter-habitat variability in reproductive strategies observed in certain *** inter-forest variability of some reproductive traits in passerines has been examined by comparing forest patches or separated ***,there is still little information regarding how such highly mobile animals adjust their breeding performance across continuous and heterogeneous *** we studied the reproductive performance of a population of Blue Tits(Cyanistes caeruleus) in an area of continuous Mediterranean woodland that included two mountain slopes and four different types of forest,ranging from deciduous oak forests to perennial non-oak *** studied the habitat heterogeneity and inter-forest phenotypic variation in terms of reproductive performance and adult and nestling biometry,besides also exploring the effects of ectoparasites on Blue Tit *** were laid earliest in deciduous Pyrenean Oak(Quercus pyrenaica) forests,while clutch size and the number of fledglings were highest in the humid Pyrenean Oak forest,which had the greatest tree coverage and most humid climate,and lowest in the coniferous Scots Pine(Pinus sylvestris) *** were no inter-forest differences in hatching(percentage of nests with at least one egg hatched) and fledging(percentage of nests in which at least one nestling fledged)***,there were no inter-forest differences in adult and nestling biometry,but adults that raised more fledglings had a lower body mass,while males whose females laid larger clutches had smaller *** ectoparasites did not affect Blue Tit reproduction,although Culicoides had a negative impact on nestling body *** results

关键词： Birds Breeding success Cavity-nesting birds Paridae Passerines Reproduction

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Sensitivity of the electronic and magnetic structures of cuprate superconductors to density functional approximations

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npj Computational Materials 2022年第1期8卷 266-276页

作者： Kanun Pokharel Christopher Lane James W.Furness Ruiqi Zhang Jinliang Ning bernardo Barbiellini Robert SMarkiewicz Yubo Zhang Arun Bansil Jianwei Sun Department of Physics and Engineering Physics Tulane UniversityNew OrleansLA70118USA Theoretical Division Los Alamos National LaboratoryLos AlamosNM87545USA Center for Integrated Nanotechnologies Los Alamos National LaboratoryLos AlamosNM87545USA Department of Physics School of Engineering ScienceLUT UniversityFI-53851LappeenrantaFinland Physics Department Northeastern UniversityBostonMA02115USA

We discuss the crystal,electronic,and magnetic structures of La_(2−x)Sr_(x)CuO_(4)(LSCO)for x=0.0 and x=0.25 employing 13 density functional approximations,representing the local,semi-local,and hybrid exchange-correlation approximations within the Perdew–Schmidt *** meta-generalized gradient approximation(meta-GGA)class of functionals is found to perform well in capturing the key properties of LSCO,a prototypical high-temperature cuprate *** contrast,the localspin-density approximation,GGA,and the hybrid density functional fail to capture the metal-insulator transition under doping.

关键词： functional electronic approximation

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Reference penile size measurement and correlation with other anthropometric dimensions:a prospective study in 800 men

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Asian Journal of Andrology 2022年第6期24卷 620-623页

作者： Martina Sole Ignacio Tobia Gonzalezi Martin Compagnucci Guadalupe Colucci Marcos Dalvit bernardo Chiconi Omar A Layus Guillermo Gueglio Gaston Rey-Valzacchi Department of Urology at Hospital Italiano Buenos Aires C1199ABBArgentina Department of Urology at Sanatorio Allende Cordoba 5000Argentina Department of Urology at Hospital Privado de la Comunidad Mar del Plata 7600Argentina Department of Urology at Hospital Central Mendoza 5500Argentina

Virility and sexual pleasure have long been associated with penile size and this,in turn,has typically been linked to some anthropometric measurements,such as foot size or height,leading to various misconceptions from both men and *** intention is to estimate penile size parameters in Argentina and evaluate the correlation between penile size and certain anthropometric *** is a cross-sectional,descriptive,multicenter,and observational *** patients who underwent a urological procedure were included in four hospitals located in different regions of the *** anthropometric measurements were obtained:height,weight,penile circumference,flaccid and stretched length,and foot length.A total of 8o0 patients were *** left foot was 26.4 *** flaccid penile length was 11.4(95%confidence interval[CI]:8-14)cm,and mean penile circumference was 10.1(95%CI:8-12)***,mean stretched penis was 15.2(95%CI:11-18.5)*** can confirm that estimates of the average penile measurements in Argentina are flaccid penis length of 11.4 cm,penile circumference of 10.1 cm,and stretching the penis to the maximum in flaccidity of 15.2 *** between flaccid penis length,stretched out,penile circumference,height,weight,and length of the left foot were evaluated,finding low or no correlation between those mentioned,exceptforflaccidand stretched length.

关键词： anthropometric measurements micropenis penile percentile

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Treatment of liver hydatidosis:How to treat an asymptomatic carrier?

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World Journal of Gastroenterology 2010年第33期16卷 4123-4129页

作者： bernardo Frider Edmundo Larrieu Department of Medicine-Hepatology Argerich HospitalUniversity of Buenos Aires Maimonides University Department of Zoonosis Ministry of Health of Rio Negro Province University of La Pampa

Liver hydatidosis is the most common clinical presentation of cystic echinococcosis(CE).Ultrasonographic mass surveys have demonstrated the true prevalence,including the asymptomatic characteristic of the majority of cases,providing new insight into the natural history of the *** raises the question of whether to treat or not to treat these patients,due to the high and unsuspected prevalence of *** high rate of liver/lung frequencies of cyst localization,the autopsy findings,and the involution of cysts demonstrated in long time follow-up of asymptomatic carriers contribute to this *** decision to treat an asymptomatic patient by surgery,albendazole,or puncture aspiration injection and reaspiration or to wait and watch,is based on conflicting reports in the literature,the lack of complications in untreated patients over time,and the spontaneous disappearance and involution of *** these points contribute to difficulties of individual clinical *** patients should be informed of the reasons and the risks of watchful/waiting without treatment,the possibility of complications,and the risks of the other *** more information on the natural history of liver hydatidosis is acquired,selection of the best treatment will be come *** this knowledge it would be very difficult to establish definitive rules of *** present,it is possible to manage these patients over time and to wait for the best moment for *** studies must be conducted to achieve this objective.

关键词： Hydatid cyst Liver Hepatic cystic echino- coccosis Albendazole Liver ultrasonography Puncture aspiration injection and reaspiration Ultrasonography screening Asymptomatic liver hydatidosis

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On Ideal Convergence of Double Sequences in Probabilistic Normed Spaces

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Acta Mathematica Sinica,English Series 2012年第8期28卷 1689-1700页

作者： Vijay KUMAR bernardo LAFUERZA-GUILLÉN Department of Mathematics Haryana College of Technology and ManagementKaithal-136027HaryanaIndia Departamento de Estadística y Matem'atica Aplicada Universidad de AlmeríaAlmería 04120Spain

The notion of ideal convergence is a generalization of statistical convecgence which has been intensively investigated in last few years. For an admissible ideal ∮ C N × N, the aim of the present paper is to introduce the concepts of ∮-convergence and ：∮＊-convergence for double sequences on probabilistic normed spaces （PN spaces for short）. We give some relations related to these notions and find condition on the ideal ∮ for which both the notions coincide. We also define ∮-Cauchy and ：∮＊- Cauchy double sequences on PN spaces and show that ∮-convergent double sequences are ∮-Cauchy on these spaces. We establish example which shows that our method of convergence for double sequences on PN spaces is more general.

关键词： Ideal convergence double sequence statistical convergence continuous t-norm and prob- abilistic normed spaces

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The role of interleukin-6 in central nervous system demyelination

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Neural Regeneration Research 2016年第12期11卷 1922-1923页

作者： Filip Petkovic bernardo Castellano Department of Cell Biology Physiology and Immunology Institute of Neuroscience Universitat Autonoma de Barcelona Bellaterra Spain Department of Immunology Institute for Biological Research "Sinisa Stankovic" Belgrade Serbia

Demyelination of the central nervous system（CNS）is a hallmark of multiple sclerosis（MS）,chronic inflammatory and neurodegenerative *** demyelination favors neurodegeneration of denuded axons,which is a major cause... 详细信息

关键词： interleukin disability neuronal irreversible despite microglia cytokine astrocyte maturation understood

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Necroptosis, pyroptosis and apoptosis: an intricate game of cell death

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Cellular & Molecular Immunology 2021年第5期18卷 1106-1121页

作者： Damien Bertheloot Eicke Latz bernardo S.Franklin Institute of Innate Immunity University Hospitals BonnUniversity of BonnBonnNRWGermany Department of Infectious Diseases and Immunology University of Massachusetts Medical SchoolWorcesterMAUSA German Center for Neurodegenerative Diseases BonnNRWGermany

Cell death is a fundamental physiological process in all living *** roles extend from embryonic development,organ maintenance,and aging to the coordination of immune responses and *** recent years,our understanding of the mechanisms orchestrating cellular death and its consequences on immunity and homeostasis has increased *** modalities of what has become known as‘programmed cell death’have been described,and some key players in these processes have been *** have learned more about the intricacies that fine tune the activity of common players and ultimately shape the different types of cell *** studies have highlighted the complex mechanisms tipping the balance between different cell ***,we summarize the latest discoveries in the three most well understood modalities of cell death,namely,apoptosis,necroptosis,and pyroptosis,highlighting common and unique pathways and their effect on the surrounding cells and the organism as a whole.

关键词： Apoptosis Necroptosis Pyroptosis Inflammation Survival

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HDL signaling and protection against coronary artery atherosclerosis in mice

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The Journal of Biomedical Research 2016年第2期30卷 94-100页

作者： bernardo L Trigatti Mark Fuller Department of Biochemistry and Biomedical Sciences McMaster University and Thrombosis and Atherosclerosis Research InstituteMcMaster University and Hamilton Health Sciences

Atherosclerosis is a leading underlying factor in cardiovascular disease and stroke,important causes of morbidity and mortality across the *** epidemiological studies demonstrate that high levels of high density lipoprotein（HDL） are associated with reduced risk of atherosclerosis and preclinical,animal model studies demonstrate that this association is *** the molecular mechanisms underlying the protective effects of HDL will allow more strategic approaches to development of HDL based *** evidence suggests that an important aspect of the ability of HDL to protect against atherosclerosis is its ability to trigger signaling responses in a variety of target cells including endothelial cells and macrophages in the vessel *** signaling responses require the HDL receptor,scavenger receptor class B type 1（SR-B1）,an adaptor protein（PDZK1） that binds to the cytosolic C terminus of SR-B1,Akt1 activation and（at least in endothelial cells） activation of endothelial NO synthase（eNOS）.Mouse models of atherosclerosis,exemplified by apolipoprotein E or low density lipoprotein receptor gene inactivated mice（apoE or LDLR KO） develop atherosclerosis in their aortas but appear generally resistant to coronary artery *** the other hand,inactivation of each of the components of HDL signaling（above）in either apoE or LDLR KO mice renders them susceptible to extensive coronary artery atherosclerosis suggesting that HDL signaling may play an important role in protection against coronary artery disease.

关键词： coronary artery disease high density lipoprotein myocardial infarction scavenger receptor class B type 1

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The regional employment implications of a net-zero economy in Costa Rica under uncertainty

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Advances in Climate Change Research 2023年第6期14卷 988-999页

作者： Maria JoséSAUMA CHACON Alejandro MATARRITA VALVERDE bernardo ZUNIGA ALVARADO Monica RODRiGUEZ-ZUNIGA Jairo QUIROs-TORTOS Luis ViCTOR-GALLARDO Pauline SCHAAL Paula CUBILLOS Thierry DUPLAN Matthieu ROBIN Slim DALI Universidad de Costa Rica San Jose 11501-2060Costa Rica Agence Frangaise de Developpement Paris 75598 France

This study estimates job creation from Costa Rica's transition to net-zero emissions by 2050,contrasting it with a business-as-usual scenario(BAU)using employment multipliers from Costa Rica's input-output *** model is soft-linked with a bottom-up technology-rich regional model of the CLEW sectors in Costa Rica.A robust decision-making-inspired approach is taken to assess the effects of uncertainty on the *** study addresses a literature gap in modeling subnational employment while accounting for long-term uncertainty and allows to identify economic activities affected by the transformation,so that policies regarding a just transition can be properly developed and stakeholders incentivized to take active participation in the *** baseline assumptions,a net-zero economy would have 135 thousand more jobs by 2050 than the BAU,equivalent to 7%of the employed population in ***-related jobs would triple by mid-21st century,and regions capitalizing on renewables would perceive the highest *** considering uncertainty,the net jobs range between 35-750 *** net positive outcomes in terms of jobs are feasible,global governance should focus efforts on policies that enhance these.

关键词： Decarbonization Environmental policy Input-output Employment multipliers Costa Rica

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