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Comparison between the SAPIEN S3 and the SAPIEN XT transcatheter heart valves:A single-center experience

World Journal of Cardiology 2016年第12期8卷 735-745页

作者： Fadi J Sawaya Marco Spaziano Thierry Lefèvre Andrew Roy Phillippe Garot Thomas Hovasse Antoinette Neylon Hakim Benamer Mauro Romano Thierry Unterseeh Marie-Claude Morice bernard chevalier Department of Cardiology Générale de SantéInstitut Cardiovasculaire Paris-Sud-Hopital Privé Jacques Cartier

AIM To investigate the clinical outcomes of transcatheter aortic valve implantation(TAVI) with the SAPIEN 3 transcatheter heart valve(S3-THV) vs the SAPIEN XT valve(XT-THV).METHODS We retrospectively analyzed 507 patients that underwent TAVI with the XT-THV and 283 patients that received the S3-THV at our institution between March 2010 and December *** Thirty-day mortality(3.5% vs 8.7%:OR=0.44,P=0.21) and 1-year mortality(25.7% vs 20.1%,P=0.55) were similar in the S3-THV and the XT-THV *** rates of both major vascular complication and paravalvular regurgitation(PVR)>1 were almost 4 times lower in the S3-THV group than the XT-THV group(major vascular complication: 2.8% vs 9.9%,P1: 2.4% vs 9.7%,P<0.0001).However,the rate of new pacemaker implantation was almost twice as high in the S3-THV group(17.3% vs 9.8%,P=0.03).In the S3 group,independent predictors of new permanent pacemaker were pre-procedural RBBB(OR=4.9:P=0.001),pre-procedural PR duration(OR=1.14,P=0.05) and device lack of coaxiality(OR=1.13:P=0.05) during *** The S3-THV is associated to lower rates of major vascular complications and PVR but higher rates of new pacemaker compared to the ***-optimal visualization of the S3-THV in relation to the aortic valvular complex during deployment is a predictor of new permanent pacemaker.

关键词： SAPIEN-3 valve Vascular complications Permanent pacemaker Lack of coaxiality Paravalvular regurgitation

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Fragrant Microcapsules Based onβ-Cyclodextrin for Cosmetotextile Application

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Journal of Renewable Materials 2019年第12期7卷 1347-1362页

作者： Maroua Ben Abdelkader Nedra Azizi Ayda Baffoun Yves chevalier Mustapha Majdoub Laboratoire des Interfaces et Matériaux Avancés(LIMA) Facultédes SciencesUniversitéde Monastirbd de l’Environnement5019 MonastirTunisia Laboratoire d’Automatique de Génie des Procédés et de Génie Pharmaceutique(LAGEPP)UniversitéClaude Bernard Lyon 1UMR CNRS 500743 bd du 11 Novembre 191869622 Villeurbanne CedexFrance Unitéde Recherche Matériaux et Procédés Textiles Universitéde MonastirÉcole Nationale d’Ingénieurs de Monastirav.Ibn Eljazzar5019 MonastirTunisia

Microencapsulation of neroline inside microcapsules having a polyurethane shell based onβ-cyclodextrin(β-CD)and hexane diisocyanate was performed by interfacial *** polyol nature ofβ-CD caused tight crosslinking of microcapsules *** of neroline were characterized for their chemical composition and structure of the polyurethane shell by FTIR spectroscopy,thermogravimetric analysis,optical and electron microscopy,light scattering and electrophoresis *** content and encapsulation yield were 15%and 60%,*** microcapsules of mean diameter 29μm were slightly cationic with an isoelectric point of ***-loaded microcapsules were fixed on cotton fabric using an impregnation *** functionalized fabric showed improved resistance to washing cycles in comparison with previously reported diol-based *** microcapsules display great potential for the long-lasting release of fragrance in the framework of cosmetotextile.

关键词： Microcapsules interfacial polycondensation β-cyclodextrin neroline cosmetotextile

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Osteocyte pericellular and perilacunar matrices as markers of bone-implant mechanical integrity

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BIOCELL 2022年第10期46卷 2209-2216页

作者： ReMY GAUTHIER HeLÈNE FOLLET ANA-MARIA TRUNFIO-SFARGHIU DELPHINE FARLAY NINA ATTIK SYLVAIN MEILLE JeRÔME chevalier DAVID MITTON Universite de Lyon CNRSINSA de LyonUniversite Claude Bernard Lyon 1MATEISUMR5510VilleurbanneF-69621France Universite de Lyon Universite Claude Bernard Lyon 1INSERMLYOS UMR 1033LyonF-69008France Universite de Lyon INSA-LyonCNRS UMR5259LaMCoSVilleurbanneF-69621France Universite de Lyon Universite Claude Bernard Lyon 1UMR CNRS 5615Laboratoire des Multimateriaux et InterfacesVilleurbanneF-69622France Universite de Lyon Universite Claude Bernard Lyon 1Faculte d’OdontologieLyonF-69008France Universite de Lyon Universite Gustave EiffelUniv Claude Bernard Lyon 1LBMC UMR_T 9406LyonF-69622France

To develop durable bone healing strategies through improved control of bone repair,it is of critical importance to understand the mechanisms of bone mechanical integrity when in contact with biomaterials and *** mechanical integrity is defined here as the adaptation of structural properties of remodeled bone in regard to an applied mechanical ***,the authors present why future investigations in bone repair and regeneration should emphasize on the matrix surrounding the *** are mechanosensitive cells considered as the orchestrators of bone remodeling,which is the biological process involved in bone *** bone cells are trapped in an interconnected porous network,the lacunocanalicular network,which is embedded in a bone mineralized extracellular *** a consequence of an applied mechanical loading,the bone deformation results in the deformation of this lacunocanalicular network inducing a shift in interstitial fluid pressure and velocity,thus resulting in osteocyte *** material environment surrounding each osteocyte,the so called perilacunar and pericellular matrices properties,define its *** this mechanical stimulation pathway is well known,the laws used to predict bone remodeling are based on strains developing at a tissue scale,suggesting that these strains are related to the shift in fluid pressure and velocity at the lacunocanalicular *** this relationship has been validated through observation in healthy bone,the fluid behavior at the bone-implant interface is more *** presence of the implant modifies fluid behavior,so that for the same strain at a tissue scale,the shift in fluid pressure and velocity will be different than in a healthy bone *** that context,new markers for bone mechanical integrity,considering fluid behavior,have to be *** viewpoint exposed by the authors indicates that the properties of the pericellular and the perilacunar

关键词： Bone mechanical integrity Osteocytes Pericellular Perilacunar Mechanosensitivity

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