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1:5 0000 SCALE TOPOGRAPHIC mAPPING IN WEST CHINA USING SPOT 5 DATA

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测绘科学 2008年第S2期33卷 25-27,9页

作者： m.bernard

On the one hand,the successful launch of the SPOT 5 satellite in 2002 can be seen as a milestone for DEm extraction and mapping,because its payload includes HRS,a stereoscopic imaging instrument devoted to collection of large *** in panchromaticmode,the HRS instrument has two telescopes,one pointing forward and one aft of the *** is thus able to cover an area of 600 km×120 km in a single pass(ie 72000 km^2 stereoscopic strips).moreover,SPOT 5 is able to collect stereoscopic triplets,through a simultaneousactivation of HRG sensors in vertical mode,which will overcome the difficulty of terrain shadow in DEm *** the extremelyprecise ancillary metadata of SPOT 5 allows accurate geometric processing with sparse ground control *** SPOT 5 stereoscopicimagery becomes one of main satellite data sources for accurate DEm extraction and quickly mapping large *** current status and coverageof stereoscopic HRS imagery as well as the metadata of SPOT 5 will be briefly *** the second hand,about 2 million km^2 in west China never has been covered by 1:50000 scale topographic maps for several *** area contains the famous Qingzang plateau with average 5000m altitude and boundless Talimu basin *** this area withtraditional methods had unimaginable difficulties and was impossible to complete at *** the high technology advancing,especially thegreat progresses in geomatics,it is the time to start to map the area with new geo-information *** in 2006,China decided to initiatea large project,named 1:50000 scale topographic mapping of west China(*** China topographic mapping project),in order to getthe 1:50000 scale topographic maps(DEm,DOm and DLG)of that area within next 5 *** we know the weather is extremely atrociousand a lot of sites are out of reach in that area,mapping from aero-born and satellite remote sensing imagery with spares ground control pointswas determined to be the main so

关键词： mapping SPOT geometric modelling DEm accuracy

The influence of pressure waves in tidal gravity records

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Geodesy and Geodynamics 2023年第1期14卷 15-25页

作者： bernard Ducarme Catholic University of Louvain Georges Lemaître Centre for Earth and Climate Research(ELI)Louvain-la-NeuveBelgium

For the reduction of atmospheric effects,observed gravity has initially been corrected by using the computed barometric admittance k of the in situ measured pressure,expressed in nms-2/hPa units and estimated by least squares ***,the local pressure changes alone cannot account for the atmospheric mass attraction and loading when the coherent pressure field exceeds a specific size,i.e.,with increasing *** overcome this difficulty,it is necessary to compute the total atmospheric effect at each station using the global pressure ***,the direct subtraction of the total gravity effect,provided by the models of pressure correction,is not yet satisfactory for S2 and other tidal components,such as K2 and P1,which include solar heating pressure *** paper identifies the origin of the problem and presents strategies to obtain a satisfactory ***,we set up a difference vector between the tidal factors of m2 and S2 after correction of the pressure and ocean tides *** vector,hereafter denoted as RES,presents the advantage of being practically insensitive to calibration *** minimum discrepancy between the tidal parameters of m2 and S2 corresponds to the minimum of the RES vector norm *** we adopt the hybrid pressure correction method,separating the local and the global pressure contribution of the models and replacing the local contribution by the pressure measured at the station multiplied by an admittance *** tested this procedure on 8 stations from the IGETS superconducting gravimeters network(former GGP network).For stations at an altitude lower than 1000 m,the value of dopt is always smaller *** discrepancy between the tidal parameters of the m2 and S2 waves is always lower than0.05% on the amplitude factors and 0.025° on the *** these stations,a correlation exists between the altitude and the value *** results at the three Central European stations Conrad,Pecny and Vienna are

关键词： Atmospheric pressure waves Atmospheric pressure correction in tidal records Atmospheric pressure models ERA5 and mERRA-2

multitarget stool DNA for colorectal cancer screening:A review and commentary on the United States Preventive Services Draft Guidelines

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World Journal of Gastrointestinal Oncology 2016年第5期8卷 450-458页

作者： Barry m Berger bernard Levin Robert J Hilsden medical Affairs Exact Sciences Corporation Scientific Advisory Board Exact Sciences Departments of medicine and Community Health Sciences University of Calgary

multitarget stool DNA(mt-sDNA) testing was approved for average risk colorectal cancer(CRC) screening by the United States Food and Drug Administration and thereafter reimbursed for use by the medicare program(2014).The United States Preventive Services Task Force(USPSTF) October 2015 draft recommendation for CRC screening included mt-s DNA as an "alternative" screening test that "may be useful in select clinical circumstances",despite its very high sensitivity for early stage *** evidence supporting mt-s DNA for routine screening use is *** clinical efficacy of mt-s DNA as measured by sensitivity,specificity,life-years gained(LYG),and CRC deaths averted is similar to or exceeds that of the other more specifically recommended screening options included in the draft document,especially those requiring annual testing *** a population with primarily irregular screening participation,tests with the highest point sensitivity and reasonable specificity are more likely to favorably impact CRC related morbidity and mortality than those depending on annual *** paper reviews the evidence supporting mt-s DNA for routine screening and demonstrates,using USPSTF's modeling data,that mt-s DNA at three-year intervals provides significant clinical net benefits and fewer complications per LYG than annual fecal immunochemical testing,high sensitivity guaiac based fecal occult blood testing and 10-year colonoscopy screening.

关键词： Colorectal cancer screening multitarget stool DNA Stool DNA The United States Preventive Services Task Force Cancer Intervention Surveillance modeling Network Fecal immunological technique modeling Interval

Convergence of random zeros on complex manifolds

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Science China mathematics 2008年第4期51卷 707-720页

作者： bernard SHIFFmAN Department of mathematics Johns Hopkins University

We show that the zeros of random sequences of Gaussian systems of polynomials of increasing degree almost surely converge to the expected limit distribution under very general hypotheses. In particular, the normalized distribution of zeros of systems of m polynomials of degree N, orthonormalized on a regular compact set K ? ? m , almost surely converge to the equilibrium measure on K as N → ∞.

关键词： random polynomial ample line bundle zeros of holomorphic sections equilibrium measure 32A60 32L10 60G99

Density Results in Sobolev Spaces Whose Elements Vanish on a Part of the Boundary

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Chinese Annals of mathematics,Series B 2011年第6期32卷 823-846页

作者： Jean-marie Emmanuel bernard Laboratoire Analyse et Probabitilités Université d'Evry val d'Essonne23 Boulevard de France91037 EVRYFrance

This paper is devoted to the study of the subspace of Wm＇＂ of functions that vanish on a part γ0 of the boundary. The author gives a crucial estimate of the Poincare constant in balls centered on the boundary of γ0. Then, the convolution-translation method, a variant of the standard mollifier technique, can be used to prove the density of smooth functions that vanish in a neighborhood of γ0, in this subspace. The result is first proved for m = 1, then generalized to the case where m 〉 1, in any dimension, in the framework of Lipschitz-continuous domain. However, as may be expected, it is needed to make additional assumptions on the boundary of γ0, namely that it is locally the graph of some Lipschitz-continuous function.

关键词： Density results Boundary value problems Sobolev spaces

Improved “cure on demand” of aromatic bismaleimide with thiol triggered by retro-Diels-Alder reaction

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Frontiers of Chemical Science and Engineering 2021年第2期15卷 330-339页

作者： Vincent Froidevaux melanie Decostanzi Abdelatif manseri Sylvain Caillol bernard Boutevin Remi Auvergne Institut Charles Gerhardt montpellier UMR 5253-CNRSUniversitede MontpellierENSCM34296 Montpellier Cedex 5France

This study focuses on the synthesis of new liquid aromatic bismaleimide monomers in order to improve self-curing on demand(SCOD)systems previously based on aliphatic *** SCOD systems are based on Diels-Alder(DA)/retro-DA *** syntheses of new different aromatic bismaleimides with ester and amide bonds are *** maleimides have been protected using DA reaction and characterized by 1H NmR analysis to determine protection rate and diastereomer *** retro-DA reactions of both aromatic and aliphatic DA adducts in presence of thiol molecules were *** analysis was monitored by 1H NmR and compared to model ***,both aromatic and aliphatic bismaleimides-based polymers were synthesized with 2-mercaptoethyl ether and thermal properties of polymers were *** glass transition temperature values ranged from–20°C to 14°C and very good thermal stabilities were observed(up to 300°C).

关键词： thiol-ene polymerization self-curing on demand thia-michael addition Diels-Alder maleimide

Effect of Bimodal Grain Size Distribution on the Strain Hardening Behavior of a medium-Entropy Alloy

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Acta metallurgica Sinica(English Letters) 2021年第4期34卷 465-475页

作者： Ibrahim Ondicho bernard Alunda Fredrick madaraka melody Chepkoech Department of mechanical Engineering Dedan Kimathi University of TechnologyPrivate bag-10143Dedan KimathiNyeriKenya materials Designand Manufacturing(MADEMA)GroupDedan Kimathi University of TechnologyPrivate Bag-10143Dedan KimathiNyeriKenya Department of mining and minerals Processing Engineering Taita Taveta UniversityP.O.Box 635-80300VoiKenya Department of mechanical Engineering Howard University23006th Street NWWashingtonDCUSA

The evolution of strain hardening behavior of the Fe_(50)(CoCrmnNi)_(50) medium-entropy alloy as a function of the fraction of recrystallized microstructure and the grain size was studied using the Hollomon and Ludwigson *** specimens under study were partially recrystallized,fully recrystallized with ultrafine-grained microstructure,and fully recrystallized with coarse *** yield strength decreases steadily as the fraction of recry stallized micro structure and grain size increases due to the recovery process and the Hall-Petch ***,the bimodal grain distribution was found to have a significant impact on strain hardening during plastic *** instance,the highest ultimate tensile strength was exhibited by a 0.97 μm specimen,which was observed to contain a bimodal grain ***,using the Ludwigson equation,the effect of the bimodal grain distribution was established from the behavior of K_(2) and n_(1) *** curves tend to show very high values in the specimens with a bimodal grain distribution compared to those that show a homogenous grain ***,the bimodal grain distribution contributes to the extensive Luders strain observed in the 0.97 μm specimen,which induces a significant deviation of the Hollomon equation at lower strains.

关键词： metals and alloy mechanical properties microstructure High-entropy alloys Plastic deformation

Inhibition of mitochondrial fatty acid oxidation in drug-induced hepatic steatosis

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Liver Research 2019年第3期3卷 157-169页

作者： bernard Fromenty INSERm UMR 1241Universitéde Rennes 1RennesFrance

mitochondrial fatty acid oxidation(mtFAO)is a key metabolic pathway required for energy production in the liver,in particular during periods of *** major consequence of drug-induced impairment of mtFAO is hepatic steatosis,which is characterized by an accumulation of triglycerides and other lipid species,such as ***,the severity of this liver lesion is dependent on the residual mitochondrial b-oxidation ***,a severe inhibition of mtFAO leads to microvesicular steatosis,hypoglycemia and liver *** contrast,moderate impairment of mtFAO can cause macrovacuolar steatosis,which is a benign lesion in the short *** some drugs can induce both microvesicular and macrovacuolar steatosis,it is surmised that severe mitochondrial dysfunction could be favored in some patients by non-genetic factors(e.g.,high doses and polymedication),or genetic predispositions involving genes that encode proteins playing directly or indirectly a role in the mtFAO *** of drugs inducing steatosis include acetaminophen(APAP),amiodarone,ibuprofen,linezolid,nucleoside reverse transcriptase inhibitors,such as stavudine and didanosine,perhexiline,tamoxifen,tetracyclines,troglitazone and valproic *** several previous articles reviewed in depth the mechanism(s)whereby most of these drugs are able to inhibit mtFAO and induce steatosis,the present review is rather focused on APAP,linezolid and *** steatogenic drugs are indeed rarely discussed in the literature as regards their ability to impair mtFAO.

关键词： Drug-induced liver injury(DILI) Steatosis mitochondria b-Oxidation Acetaminophen(APAP) Troglitazone

Palaeogeography of a shallow carbonate platform:The case of the middle to Late Oxfordian in the Swiss Jura mountains

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Journal of Palaeogeography 2015年第3期4卷 251-268页

作者： André Strasser bernard Pittet Wolfgang Hug Department of Geosciences University of Fribourg Université Lyon 1 UMR CNRS LGLTPE 5276Campus DouaBatiment Géode69622 VilleurbanneFrance Paléontologie A16 Section d'archéologie et paléontologieOffice de la cultureH?tel des Halles2900 PorrentruySwitzerland

The Oxfordian （Late Jurassic） carbonate-dominated ptatform outcropping in the Swiss Jura mountains offers a good biostratigraphic, sequence-stratigraphic, and cyclostratigraphic framework to reconstruct changes in facies distribution at a time-resolution of 100 ka. It thus allows interpreting the dynamic evolution of this platform in much more detail than conventional palaeogeographic maps permit. As an example, a middle to Late Oxfordian time slice is presented, spanning an interval of about 1.6 ma. The study is based on 12 sections logged at cm-scale. The interpreted depositional environments include marginal-marine emerged ;ands, fresh-water lakes, tidal fiats, shallow lagoons, ooid shoals, and coral reefs. Although limestones dominate, marly intervals and dolomites occur sporadically. major facies shifts are related to m-scale sea-level changes linked to the orbital short eccentricity cycle （100 ka）. The 20-ka precession cycle caused minor facies changes but cannot always be resolved. Synsedimentary tectonics induced additional accommodation changes by creating shallow basins where days accumulated or highs on which shoals or islands formed. Autocyclic processes such as lateral migration of ooid and bioclastic shoals added to the sedimentary record. CEimate changes intervened to control terrestrial run-off and, consequently, siliciclastic and nutrient input. Coral reefs reacted to such input by becoming dominated by microbialites and eventually by being smothered. Concomitant occurrence of siliciclastics anddolomite in certain intervals further suggests that, at times, it was relatively arid in the study area but there was rainfall in more northern latitudes, eroding the Hercynian substrate. These examples from the Swiss Jura demonstrate the highly dynamic and （geologically speaking） rapid evolution of sedimentary systems, in which tectonically controlled basin morphology, orbitally induced climate and sea-level changes, currents, and the ecology of the carbon

关键词： Swiss Jura Oxfordian carbonate platform facies evotution sequence stratigraphy cyclostratigraphy