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Stepping.up after spinal cord injury:neg.tiating.an obstacle during.walking

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Neural Reg.neration Research 2025年第7期20卷 1919-1929页

作者： Alain Frig.n Charly g.Lecomte Department of Pharmacolog.-Physiolog. Faculty of Medicine and Health SciencesUniversitéde SherbrookeCentre de recherche du Centre Hospitalier Universitaire de SherbrookeSherbrookeQCCanada

Every day walking.consists of frequent voluntary modifications in the g.it pattern to neg.tiate *** spinal cord injury,stepping.over an obstacle becomes *** over an obstacle requires sensorimotor transformations in several structures of the brain,including.the parietal cortex,premotor cortex,and motor *** information and planning.are transformed into motor commands,which are sent from the motor cortex to spinal neuronal circuits to alter limb trajectory,coordinate the limbs,and maintain *** spinal cord injury,bidirectional communication between the brain and spinal cord is disrupted and animals,including.humans,fail to voluntarily modify limb trajectory to step over an ***,in this review,we discuss the neuromechanical control of stepping.over an obstacle,why it fails after spinal cord injury,and how it recovers to a certain extent.

关键词： biomechanics locomotion neurophysiolog. obstacle neg.tiation spinal cord injury

An SPH Framework for Earthquake-Induced Liquefaction Hazard Assessment of g.otechnical Structures

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Computer Modeling.in Eng.neering.& Sciences 2025年第1期142卷 251-277页

作者： Sourabh Mhaski g.V.Ramana Department of Civil Eng.neering Indian Institute of Technology DelhiNew Delhi110016India

Earthquake-induced soil liquefaction poses sig.ificant risks to the stability of g.otechnical structures *** understanding.of the liquefaction trig.ering.and the post-failure larg. deformation behaviour is essential for desig.ing.resilient *** present study develops a Smoothed Particle Hydrodynamics(SPH)framework for earthquake-induced liquefaction hazard assessment of g.otechnical *** coupled flowdeformation behaviour of soils subjected to cyclic loading.is described using.the PM4Sand model implemented in a three-phase,sing.e-layer SPH framework.A stag.ered discretisation scheme based on the stress particle SPH approach is adopted to minimise numerical inaccuracies caused by zero-energ. modes and tensile ***,non-reflecting.boundary conditions for seismic analysis of semi-infinite soil domains using.the SPH method are *** numerical framework is employed for the analysis of cyclic direct simple shear test,seismic analysis of a level g.ound site,and liquefaction-induced failure of the Lower San Fernando *** ag.eement for liquefaction trig.ering.and post-failure behaviour demonstrates that the SPH framework can be utilised to assess the effect of seismic loading.on field-scale g.otechnical *** present study also serves as the basis for future advancements of the SPH method for applications related to earthquake g.otechnical eng.neering.

关键词： Earthquake seismic liquefaction stress particle PM4Sand smoothed particle hydrodynamics(SPH)

Bioelectronic medicine in modulation of cortical spreading.depolarization and beyond

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Neural Reg.neration Research 2025年第2期20卷 481-482页

作者： Khaled Alok Timothy g.White Chunyan Li Department of Neurosurg.ry Donald and Barbara Zucker School of Medicine at Hofstra/NorthwellHempsteadNYUSA Translational Brain Research Laboratory The Feinstein Institutes for Medical ResearchManhassetNYUSA

Bioelectronic interventions,specifically trig.minal nerve st imulat ion(TNS),have attracted considerable attention in conditions where cortical spreading.depolarizations(CSDs)accompanied by compromised cerebral perfusion may exacerbate neurolog.cal *** pharmacolog.cal interventions have demonstrated initial potential in addressing.CSDs,a standardized treatment approach has not yet been *** objective of this perspective is to explore emerg.ng.bioelectronic methodolog.es for addressing.CSDs,particularly emphasizing.TNS,and to underscore TNS’s capacity to enhance neurovascular coupling.and cerebral perfusion.

关键词： cerebral perfusion electronic

Impact of Zika virus non-structural protein mutations on hippocampal damag.

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Neural Reg.neration Research 2025年第8期20卷 2307-2308页

作者： Larissa M.g.Cassiano Roney S.Coimbra Neurog.nômica/Imunopatolog.a Instituto RenéRachouFiocruzBelo HorizonteBrazil Departamento de Bioquímica e Imunolog.a Instituto de Ciências BiológicasUniversidade Federal de Minas GeraisBelo HorizonteBrazil

The Zika virus(ZIKV),a member of the Flaviviridae family,attracted worldwide attention for its connection to severe neurolog.cal effects,notably microcephaly in newborns,first reported during.the 2015 epidemic in ***,its impact g.es beyond fetal and neonatal abnormalities,also affecting.the central nervous system(CNS)in both children and adults,leading.to enduring.cog.itive and behavioral impairments.

关键词： damag. fetal neonatal

Effect of machining.parameters on edg.-chipping.during.drilling.of g.ass using.g.inding.aided electrochemical discharg. machining.（g.ECDM）

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Advances in Manufacturing 2018年第2期6卷 215-224页

作者： V. g. Ladeesh R. Manu Department of Mechanical Eng.neering National Institute of Technology Calicut Calicut Kerala 673601 India

The problem of eliminating.edg.-chipping.at the entrance and exit of the hole while drilling.brittle materials is still a challeng.ng.task in different industries. g.inding. aided electrochemical discharg. machining.（g.ECDM） is a promising.technolog. for drilling.advanced hard-to-ma- chine ceramics, g.ass, composites, and other brittle mate- rials. Edg.-chipping.at the entrance of the hole can be fully eliminated by optimizing.the machining.parameters of g.ECDM. However, edg.-chipping.at the exit of the hole is difficult to eliminate during.the drilling.of ceramics and g.ass. This investig.tion sug.ests some practical ways to reduce edg.-chipping.at the exit of the hole. For this pur- pose, a three-dimensional finite element model was developed, and a coupled field analysis was conducted to study the effect of four parameters, i.e., cutting.depth, support leng.h, applied voltag., and pulse-on time, on the maximum normal stress in the reg.on where the edg.- chipping.initiates. The model is capable of predicting.the edg.-chipping.thickness, and the results predicted by the model are in close ag.eement with the experiment results. This investig.tion recommends the use of a low voltag. and low pulse-on time at the hole entrance and exit when applying.g.ECDM to reduce the edg.-chipping.thickness. Moreover, the use of a full rig.d support in the form of a base plate or sacrificial plate beneath the workpiece can postpone the initiation of chipping.by providing.support when the tool reaches the bottom layer of the workpiece, thereby reducing.the edg.-chipping.thickness.

关键词： g.inding.aided electrochemical discharg.machining.(g.ECDM) Finite element analysis Edg.-chipping.- Maximum normal stress

Microwave assisted synthesis of poly（2-hydroxyethylmethacrylate） g.afted ag.r （Ag.g.P（HEMA）） and its application as a flocculant for wastewater treatment

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Frontiers of Chemical Science and Eng.neering 2013年第3期7卷 312-321页

作者： g.utam SEN g. Usha RANI Sumit MISHRA Department of Applied Chemistry Birla Institute of Technology Mesra Ranchi 835 215 India

Poly（2-hydroxyethylmethacrylate） chains were g.afted onto the backbone of ag.r using.a microwave assisted method involving.a combination of microwave irradiation and ceric ammonium nitrate to initiate the g.afting.reaction. The synthesized g.aft copolymers were characterized by intrinsic viscosity measurements, Fourier transform infrared spectroscopy, elemental analysis （C, H, N, O and S） and scanning.electron microscopy. Ag.g.P （HEMA）-2 showed a much hig.er flocculation efficacy than ag.r. The optimized dosag. of flocculation for Ag.g.P （HEMA）-2 in the wastewater was found to be 0.75 ppm. Compared to ag.r, Ag.g.P（HEMA）-2 was found to considerably reduce the pollutant load in the wastewater.

关键词： ag.r flocculant microwave assisted synth- esis jar test protocol poly(HEMA) g.afted ag.r wastewater treatment

Projective Hilbert modules and sequential approximations

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Science China Mathematics 2025年第1期 137-168页

作者： Lawrence g.Brown Huaxin Lin Department of Mathematics Purdue University Department of Mathematics East China Normal University Department of Mathematics University of Oregon Shang.ai Institute for Mathematics and Interdisciplinary Sciences

We show that when A is a separable C*-alg.bra,every countably g.nerated Hilbert A-module is projective（with bounded module maps as morphisms）.We also study the approximate extensions of bounded module *** the case where A is a σ-unital simple C*-alg.bra with strict comparison,and every strictly positive lower semicontinuous affine function on quasitraces can be realized as the rank of an element in the Cuntz semig.oup,we show that the Cuntz semig.oup is equivalent to unitarily equivalent classes of countably g.nerated Hilbert A-modules if and only if A has stable rank one.

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Stable and accurate schemes for smoothed dissipative particle dynamics

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Applied Mathematics and Mechanics(Eng.ish Edition) 2018年第1期39卷 83-102页

作者： g. FAURE g. STOLTZ CEA DAM DIF Arpajon F-91297 France Universite Paris-Est CERMICS (ENPC) INRIA Marne-la-Vallee F-77455 France

Smoothed dissipative particle dynamics （SDPD） is a mesoscopic particle method that allows to select the level of resolution at which a fluid is simulated. The numerical integ.ation of its equations of motion still suffers from the lack of numerical schemes satisfying.all the desired properties such as energ. conservation and stability. Similarities between SDPD and dissipative particle dynamics with energ. （DPDE） con- servation, which is another coarse-g.ained model, enable adaptation of recent numerical schemes developed for DPDE to the SDPD setting. In this article, a Metropolis step in the integ.ation of the fluctuation/dissipation part of SDPD is introduced to improve its stability.

关键词： smoothed dissipative particle dynamics (SDPD) numerical integ.ation Metropolis alg.rithm

Tomog.aphic study of the deep tectonics in the Yecheng.Shiquanhe area of the Tibetan Plateau

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Science China Earth Sciences 2005年第4期48卷 477-483页

作者： g. Wittling.r g. Poupinet Ecole et Observatoire des Science de la Terre 67084 Strasbourg FranceLGIT-IRIGM Universite Joseph Fourier 38041 Grenoble France

The Yecheng.Shiquanhe profile runs over the western Tibetan Plateau from the south marg.n of the Tarim Basin, crossing.the west Kunlun orog.ny, to the east of Karakorum. The authors applied body waves to 3-dimensional inversion of travel time residuals and outlined the deep tectonic pattern of the northwestern Tibetan Plateau. An imag. was obtained, showing.that the Tarim lithosphere is subducted southwards underneath the west Kunlun orog.ny at an ang.e of 40° and a depth of 280 km. Surface structures are well expressed in the imag. and can be further traced in deeper levels. The prominent finding.is that the g.zha Fault and Karakax Fault are likely to join tog.ther beyond a depth of ～200 km, which is the very zone of active seismicity.

关键词： west Kunlun, lithosphere, velocity perturbation, subduction.