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Chemotaxonomic Study of the Covid-Organics of Madagascar Based on the Chemical Composition of Their Essential Oils

International Journal of Organic Chemistry 2023年第2期13卷 50-56页

作者： Yoro Tine Adama Diédhiou Alioune Diallo Idrissa Ndoye Mamadou Baldé Cheikhouna Gaye benjamin ndiaye Alassane Wélé Djibril Fall Laboratoire de Chimie Organique et Thé rapeutique Facult&eacute de M&eacutedecine Pharmacie et Odontologie Universit&eacute Cheikh Anta Diop Dakar S&eacuten&eacutegal

The aim of this study was to investigate the chemical composition of the essential oils of “Covid-Organics” of Madagascar (62% Artemisia annua and two other undisclosed medicinal plants) used as curative and preventive treatments of Covid-19, to identify its constituent species. The essential oils isolated by hydro-distillation from two samples (curative and preventive) were analyzed by GC-FID and GC-MS. These essential oils (curative and preventive) were mainly dominated by camphor (17.9% and 11.9%, respectively), spathulenol (4.8% and 11.8%, respectively), α-acorenol (4.3% and 3.7%, respectively), (E)-β-caryophyllene (3.4% and 4.2%, respectively), 1,8-cineole (3.1% and 3.6%, respectively), hexadecanoïc acid (3.8% and 3.2%, respectively) and caryophyllene oxide (3.4% and 2.4%, respectively). From the chemical composition, two species were identified, A. annua characterised by camphor and Cinnamomumcamphora (Ravintsara) characterised by 1,8-cineole and sabinene. However, we were unable to identify the third species.

关键词： Covid-19 Covid-Organics Artemisia annua Essential Oils Chemotaxonomic

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Chemical Variability and Antibacterial Activity of Eucalyptus camaldulensis Essential Oils from Senegal

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International Journal of Organic Chemistry 2022年第4期12卷 173-180页

作者： Yoro Tine Alioune Diallo Idrissa Ndoye Cheikhouna Gaye benjamin ndiaye Abdoulaye Diop Jean Costa Cheikh Saad Bouh Boye Alassane Wélé Julien Paolini Laboratoire de Chimie Organique et Thérapeutique Faculté de Médecine Pharmacie et Odontologie Université Cheikh Anta Diop Dakar Senegal Université de Corse UMR CNRS 6134 SPE Laboratoire de Chimie des Produits Naturels Campus Grimaldi Corte France Laboratoire de Bactériologie-virologie H&ocirc pital Aristide Le Dantec Dakar Senegal

1,8-cineole, also known as eucalyptol, is the main constituent and the most important of the leaf oils of many species of the genus Eucalyptus. In present study, the essential oils isolated by hydrodistillation from the leaves of Eucalyptus camaldulensis from six different locations were analyzed by GC-FID and GC-MS. Essential oil yields ranged from 0.33% to 4.35%. In total, 34 constituents were identified, accounting for 94.0% to 99.8% of the total compositions. 1,8-cineole (46.4% - 84.4%) was the main constituent of all the essential oil samples, except for one sample collected in the Fatick region, which had p-cymene (46.4%) and 1,8-cineole (26.0%) as major compounds. The essential oil showed excellent activity against S. aureus, E. coli and E. faecalis (IZ = 25.3 ± 1.2 mm;18.7 ± 0.6 mm;17.8 ± 0.3 mm, respectively) and moderate activity against P. aeruginosa (IZ = 10.8 ± 0.8 mm). They may have potential applications in food and pharmaceutical products.

关键词： Eucalyptus camaldulensis Essential Oils Antibacterial Activity 1 8-Cineole and GC-SM

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Chemotaxonomic Study of the Covid-Organics of Madagascar Based on the Chemical Composition of Their Essential Oils

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International Journal of Organic Chemistry（有机化学国际期刊） 2023年第2期

作者： Yoro Tine Adama Diédhiou Alioune Diallo Idrissa Ndoye Mamadou Baldé Cheikhouna Gaye benjamin ndiaye Alassane Wélé Djibril Fall

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Chemical Variability and Antibacterial Activity of Eucalyptus camaldulensis Essential Oils from Senegal

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International Journal of Organic Chemistry（有机化学国际期刊） 2022年第4期

作者： Yoro Tine Alioune Diallo Idrissa Ndoye Cheikhouna Gaye benjamin ndiaye Abdoulaye Diop Jean Costa Cheikh Saad Bouh Boye AlassaneWélé Julien Paolini

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Introduction of monkeypox virus in Benin,2022

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军事医学研究:英文版 2023年第4期10卷 572-574页

作者： Anges Yadouleton Martin Faye Carine Tchibozo Mariam Oke Oumar Faye Thierry Lawale Eric Denon RenéKeke Ange Dossou Alban Zohoun Francis Dossou Moussa Moise Diagne Sourakou Salifou Khadija Leila Diatta Mignane ndiaye Safietou Sankhe Amadou Diallo Sonia Bedie Clément Glele-Kakai Al Fattah Onifade Raoul Saizonou Gildas Hounkanrin Olga Quenum Yvette Badou benjamin Hounkpatin Amadou Alpha Sall Ousmane Faye Laboratoire des Fièvres Hémorragiques Virales(LFHV) Ministry of Health of Benin01-882CotonouBenin Ecole Normale Supérieure de Natitingou UniversitéNationale des SciencesTechnologiesIngénierie et Mathématiques(UNSTIM)2282GohoAbomeyCotonouBenin Virology Department Institut Pasteur de Dakar36 Avenue Pasteur220DakarSenegal Ministry of Health of Benin 01-882CotonouBenin National Public Health Laboratory Ministry of Health of Benin01-882CotonouBenin Epidemiology Clinical Research and Data Science DepartmentInstitut Pasteur de Dakar220DakarSenegal WHO Country Office in Benin Avenue CENSAD-Les Cocotiers01BP 918CotonouBenin

Dear Editor,Monkeypox is an infectious disease that is endemic in a dozen of African *** imported cases have been also reported outside of Africa in the past[1].Since early May 2022,monkeypox infections including human-to-human transmission,were reported in a multi-country outbreak in non-endemic countries and declared Public Health Emergency of International Concern(PHEIC)by the World Health Organization(WHO)in July 2022[2].As of 20 September 2022,a total of at least 62,798 human cases of monkeypox with 20 deaths have been confirmed in 115 countries in five WHO regions[3].

关键词： Monkeypox virus Introduction Human-to-human transmission Benin

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