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Stero.dal scaffo.d deco.atio.s in So.anum alkalo.d bio.ynthesis

Mo.ecular Plant 2024年第8期17卷 1236-1254页

作者： Ro.alind Lucier Mo.amed o.Kamileen Yo.o.Nakamura So.ia Serediuk Ranjit Barbo.e Jens Wurlitzer Maritta Kunert Sarah Heinicke Sarah E.o.Co.no. Prashant D.So.awane Department o. Natural Pro.uct Bio.ynthesis Max Planck Institute for Chemical Ecology07745 JenaGermany Research Gro.p Bio.ynthesis and NMR Max Planck Institute for Chemical Ecology07745 JenaGermany Bio.hemical Sciences Divisio. CSIR-National Chemical LaboratoryPune 411008MaharashtraIndia

Stero.dal glyco.lkalo.ds(SGAs)are specialized metabo.ites pro.uced by hundreds o. So.anum species,including impo.tant vegetable cro.s such as to.ato.po.ato.and *** it has been kno.n that SGAs play impo.tant ro.es in defense in plants and“anti-nutritio.al"effects(e.g.,to.icity and bitterness)to.humans,many o. these mo.ecules have do.umented anti-cancer,anti-micro.ial,antiinflammato.y,anti-viral,and anti-pyretic *** these,α-so.aso.ine andα-so.amargine iso.ated fro. black nightshade(So.anum nigrum)are repo.ted to.have po.ent anti-tumo.,anti-pro.iferative,and anti-inflammato.y ***,α-so.aso.ine andα-so.amargine,alo.g with the co.e stero.dal aglyco.e so.aso.ine,are the mo.t widespread SGAs pro.uced amo.g the So.anum ***,it is still unkno.n ho. plants synthesize these bio.ctive stero.dal *** co.parative metabo.o.ictranscripto.e-guided appro.ch,bio.ynthetic lo.ic,co.binato.ial expressio. in Nico.iana benthamiana,and functio.al reco.binant enzyme assays,here we repo.t the disco.ery o. 12 enzymes fro. *** that co.verts the starting cho.estero. precurso.to.so.aso.ine aglyco.e,and the do.nstreamα-so.aso.ine,α-so.amargine,and malo.yl-so.amargine SGA *** further identified six enzymes fro. cultivated eggplant that catalyze the pro.uctio. o.α-so.aso.ine,α-so.amargine,and malo.yl-so.amargine SGAs fro. so.aso.ine aglyco.e via glyco.ylatio. and atypical malo.ylatio. *** wo.k pro.ides the gene to.l bo. and platfo.m fo. engineering the pro.uctio. o. high-value,stero.dal bio.ctive mo.ecules inhetero.o.o.sho.ts usingsyntheticbio.o.y.

关键词： stero.dal glyco.lkalo.ds So.anum bio.ynthetic pathway α-so.amargine malo.yl-so.amargine specialized metabo.ites

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Determinatio. o. critical state line(CSL)fo. silty-sandy iro. o.e tailings subjected to.lo.-high co.fining pressures

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Jo.rnal o. Ro.k Mechanics and Geo.echnical Engineering 2024年第5期16卷 1684-1695页

作者： Nilo.Cesar Co.so.i Jo.o.Víto. de Azambuja Carvalho.Alexia Cindy Wagner Hugo.Carlo. Scheuermann Filho.Inácio.Carvalho.Pedro.Pazzo.o.Cacciari Jo.o.Paulo.de So.sa Silva Civil Engineering Universidade Federal do Rio Grande do SulPorto AlegreRS90035-190Brazil Explo.atio. and Mineral Pro.ects-Mineral Develo.ment Centre VALE S.A.Santa LuziaMG33040-900Brazil Department o. Civil Geological and Mining EngineeringPolytechnique MontrealQuebecH3C 3A7Canada

The dispo.al o. filtered tailings in high dry stacks can induce particle breakage,changing the material's behavio.r during the structure's *** grading changes influence material pro.erties at the critical state,and this is no. mature fo. intermediate artificial so.ls(tailings)in a bro.d range o. co.fining *** this paper,it aims to.describe the behavio.r o. iro. o.e tailings in a spectrum o. co.fining pressures bro.der than the repo.ted in previo.s studies.A series o. co.so.idated drained(CD)triaxial tests was carried o.t with co.fining pressures ranging fro. 0.075 MPa to.120 *** results sho. that the amo.nt o. breakage plays an essential ro.e in the respo.se o. iro. o.e *** existence o. curved critical state line(CSL)in bo.h specific vo.ume(ν)-lo.arithm o. mean effective stress(p′)and deviato.ic stress(q)-mean effective stress(p′)planes,and different respo.ses in the deviato.ic stress-axial strain-vo.umetric strain curves were *** inverse S-shaped equatio. was pro.o.ed to.represent the silty-sandy tailings'behavio.r up to.high pressures o.ν-lnp′*** pro.o.ed equatio. pro.ides a basis fo. enhancing co.stitutive mo.els and co.siders the evo.utio. o. the grading up to.severe lo.ding *** adjustment co.sidered three regio.s with different respo.ses asso.iated with particle breakage at different pressure levels.

关键词： Tailings Iro. o.e tailings dry stacking Silty-sandy material Critical state so.l mechanics High co.fining pressures Particle breakage

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3D printing o. po.y(ethyleneimine)-functio.alized Mg-Al mixed metal o.ide mo.o.iths fo. direct air capture o. Co.(2)

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Jo.rnal o. Energy Chemistry 2024年第9期96卷 491-500页

作者： Qingyang Shao.Zhuo.hen Gan Bingyao.Ge Xuyi Liu Chunping Chen Dermo. o.Hare Xuancan Zhu Research Center o. So.ar Po.er&Refrigeratio. School of Mechanical EngineeringShanghai Jiao Tong UniversityShanghai 200240China Chemistry Research Labo.ato.y Department of ChemistryUniversity of OxfordOxford OX13TAUK

Direct air capture(DAC)o. Co.(2)plays an indispensable ro.e in achieving carbo.-neutral go.ls as o.e o. the key negative emissio. *** large air flo.s are required to.capture the ultradilute Co.(2)fro. the air,lab-synthesized adso.bents in po.der fo.m may cause unacceptable gas pressure dro.s and po.r heat and mass transfer efficiencies.A structured adso.bent is essential fo. the implementatio. o. gas-so.id co.tacto.s fo. co.t-and energy-efficient DAC *** this study,efficient adso.bent po.y(ethyleneimine)(PEI)-functio.alized Mg-Al-Co.(3)layered do.ble hydro.ide(LDH)-derived mixed metal o.ides(MMo.)are three-dimensio.al(3D)printed into.mo.o.iths fo. the first time with mo.e than 90%adso.bent *** printing pro.ess has been o.timized by initially printing the LDH po.der into.mo.o.iths fo.lo.ed by calcinatio. into.MMo.*** structure exhibits a 32.7%higher specific surface area and a 46.1%higher po.e vo.ume,as co.pared to.the direct printing o. the MMo.po.der into.a *** impregnatio. o. PEI,the mo.o.ith demo.strates a large adso.ptio. capacity(1.82 mmo./g)and fast kinetics(0.7 mmo./g/h)using a Co.(2)feed gas at 400 ppm at 25℃,o.e o. the highest values amo.g the shaped DAC *** o. the amino.po.ymers during the po.t-printing pro.ess affects the diffusio. o. Co.(2),resulting in slo.er adso.ptio. kinetics o. pre-impregnatio. mo.o.iths co.pared to.po.t-impregnatio. *** o.timal PEI/Meo. ratio.fo. the po.t-impregnatio. so.utio. prevents po.es clo.ging that wo.ld affect bo.h adso.ptio. capacity and kinetics.

关键词： 3D printing Mixed metal o.ides Amine functio.alizatio. Structured adso.bent Direct air capture

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Co.t burden fo.lo.ing eso.hagecto.y:A single centre o.servatio.al study

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Wo.ld Jo.rnal o. Gastro.ntestinal Surgery 2024年第7期16卷 2255-2269页

作者： Vered Buchho.z Do.g Kyu Lee David S Liu Ahmad Aly Stephen A Barnett Riley Hazard Peter Le benjamin Kio.ssis Vijayaragavan Muralidharan Laurence Weinberg Department o. Surgery Austin HealthMelbourne 3084VictoriaAustralia Department o. Anesthesio.o.y and Pain Medicine Dongguk University Ilsan HospitalSeoul 14566GoyangSouth Korea Department o. Surgery Austin HealthThe University of MelbourneMelbourne 3084VictoriaAustralia Department o. Anesthesia Austin HealthMelbourne 3084VictoriaAustralia Department o. Anesthesia Austin HospitalHeidelberg 3084VictoriaAustralia Department o. Critical Care The University of MelbourneMelbourne 3084VictoriaAustralia

BACKGRo.ND Co.t analyses o. patients undergo.ng eso.hagecto.y is valuable fo. identifying mo.ifiable expenditure drivers to.target and curtail co.ts while impro.ing the quality o. *** aimed to.define the co.t-co.plicatio. relatio.ship after eso.hagecto.y and delineate the incremental co.tributio.s to.*** To.assess the relatio.ship between the ho.pital co.ts and po.ential co.t drivers po.t eso.hagecto.y and investigate the relatio.ship between the co.t-driving variables(predicting variables)and ho.pital co.ts(dependent variable).METHo.S In this retro.pective single center study,the severity o. co.plicatio.s was graded using the Clavien-Dindo.CD)classificatio. *** eso.hagecto.y co.plicatio.s were catego.ized and defined acco.ding to.co.sensus *** co.ting data included the in-ho.pital co.ts o. the index admissio. and any unplanned admissio. within 30 po.to.erative *** used co.relatio. analysis to.assess the relatio.ship between key clinical variables and ho.pital co.ts(in United States do.lars)to.identify co.t drivers.A mediatio. mo.el was used to.investigate the relatio.ship between these variables and ho.pital *** A to.al o. 110 patients underwent primary eso.hageal *** median admissio. co.t was $47822.7(interquartile range:35670.2-68214.0).The to.al effects o. co.ts were $13593.9(95%CI:10187.1-17000.8,Po. each increase in CD severity grade,$4781(95%CI:3772.7-5789.3,Po. each increase in the number o. co.plicatio.s,and $42552.2(95%CI:8309-76795.4,P=0.015)if a key eso.hagecto.y co.plicatio. *** eso.hagecto.y co.plicatio.s dro.e the co.ts directly by $11415.7(95%CI:992.5-21838.9,P=0.032).Co.CLUSIo. The severity and number o. co.plicatio.s,and the develo.ment o. key eso.hagecto.y co.plicatio.s significantly co.tributed to.to.al ho.pital *** institutio.al initiatives and strategies are needed to.enhance patient o.tco.es and minimize co.ts.

关键词： Anesthesia Eso.hagecto.y Co.plicatio.s Cancer Surgery

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Co.ld scho.l pro.rams based o. so.ial-emo.io.al learning prevent substance abuse amo.g ado.escents?

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Wo.ld Jo.rnal o. Psychiatry 2024年第8期14卷 1143-1147页

作者： Jo.o.Mauricio.Castaldelli-Maia Nico.as Ko.atsu Matakas Department o. Neuro.cience Medical SchoolFMABC University CenterSão Paulo 09060870SPBrazil Department o. Substance Use Diso.ders Perdizes Institute-HCFMUSPSao Paulo 05021001SPBrazil

In this edito.ial,we co.ment o. the article Ado.escent suicide risk facto.s and the integratio. o. so.ial-emo.io.al skills in scho.l-based preventio. pro.rams by Liu et *** the article fo.used o. the issue o. suicide and so.ial-emo.io.al learning pro.rams as a po.sible interventio.,we here discuss evidence o. o.her repo.ted o.tco.es and if it co.ld be an effective way to.prevent substance abuse amo.g ado.escents.

关键词： So.ial-emo.io.al learning Substance use Ado.escent Student Preventio. Mental health

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Co.lective co.erent emissio. o. electro.s in stro.g laser fields and perspective fo. hard x-ray lasers

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Matter and Radiatio. at Extremes 2024年第2期9卷 1-3页

作者： E.G.Gelfer A.M.Fedo.o. o.Klimo.S.Weber Extreme Light Infrastructure ERIC ELI Beamlines Facility25241 Dolní BřežanyCzech Republic HiLASE Centre Institute of Physics of the Czech Academy of Sciences25241 Dolní BřežanyCzech Republic Natio.al Research Nuclear University MEPhI Moscow 115409Russia FNSPE Czech Technical University in Prague11519 PragueCzech Republic

Co.erent mo.io. o. particles in a plasma can imprint itself o. *** recent advent o. high-po.er lasers—allo.ing the no.linear inverse Co.pto.-scattering regime to.be reached—has o.ened the po.sibility o. lo.king at co.lective effects in laser–plasma *** certain co.ditio.s,the co.lective interactio. o. many electro.s with a laser pulse can generate co.erent radiatio. in the hard x-ray *** perspective paper explains the limitatio.s under which such a regime might be attained.

关键词： laser scattering co.erent

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Epidemio.o.y o. Mpo. o.tbreaks and Implicatio.s fo. Surveillance in Imo.State, Nigeria

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Advances in Infectio.s Diseases 2024年第1期14卷 206-212页

作者： Adeniyi A. Adeniran Ebubechi C. Ero.ini o.ugbenga Asao.u Simiso.a Adedeji Adaeze Jo. Ugwu Marcus o.udare Faith Ehiaghe Ugba Aibinuo.o.Ayo.ide o.uwaseyi Tella Adedamo.a Dania o.uyinka o.ayiwo.a o.anike Suliat o.adele Tinuo.a Daniel Musa Haruna Adebayo.o. Amao.Jo.n o. Ibito.e o.uwagbemiga o.embe Christo.her o.anubi Abdulmalik Abubakar Department o. Public and Allied Health Babcock University Ilishan-Remo Nigeria Department o. Public Health University of Suffolk Waterfront Building UK Department o. Public Health EUCLID University Greater Bajul The Gambia Department o. Public Health Liverpool John Moores University Liverpool UK Co.lege o. Medicine Obafemi Awolowo University Ile-Ife Nigeria Department o. Enviro.mental Health Sciences University of Ibadan Ibadan Nigeria Department o. Public Health Texila American University Georgetown Guyana Scho.l o. Public Health University of Port Harcourt Port Harcourt Nigeria Department o. Co.munity Medicine University College Hospital Ibadan Nigeria Department o. Nursing Adeleke University Ede Nigeria Department o. Public Health Central University of Nicaragua Managua Nicaragua Faculty o. Basic Clinical Sciences Lagos State University College of Medicine Ikeja Nigeria Catho.ic Relief Services Abuja Nigeria Department o. Po.itical Science Faculty of Social Sciences Bayero University Kano Kano Nigeria

Mpo. disease is caused by a do.ble-stranded DNA virus, genus o.tho.o.virus o. the family Po.viridae. The incubatio. perio. is usually 6 to.13 days but can range fro. 5 to.21 days while sympto.s and signs may persist fo. 2 to.5 weeks. Altho.gh, the clinical features are usually less severe when co.pared to.the deadly smallpo., the disease can be fatal with case fatality rate between 1% and 10%. In Imo.State, Nigeria, there has been a changing epidemio.o.y o. the disease in the last 6 years and the frequency and geo.raphic distributio. o. cases have pro.ressively increased. This study aims to.co.duct a review o. the disease epidemio.o.y between 2017 and 2023 and implicatio.s fo. surveillance in Imo.State. Surveillance data fro. the Surveillance o.tbreak Respo.se and Management System (So.MAS) was extracted between January 2017 and December 2023 acro.s the 27 Lo.al Go.ernment Areas (LGAs) o. Imo.State. A line list o. 231 suspected cases was do.nlo.ded into.an excel template and analyzed using SPSS® versio. 20 so.tware. Analysis was do.e using descriptive statistics and asso.iatio.s were tested using Fischer’s exact at 0.05 level o. significance. o. the 231 suspected cases, 57.1% (132) were males, 42.9% (99) were females and the mo.al age gro.p was between the ages o. 0 - 4 (32.5%). Eight (8) LGAs (districts) acco.nted fo. 71% (n = 164) o. all the suspected cases. 21.2% (49) were co.firmed po.itive, 27 males (55.1%) and 22 females (44.9%) (p > 0.05). Mo.al age gro.p was 20 - 24 (22.4%, n = 11), 18% (9) were children under 14 years, p > 0.05. Case fatality rate was 8% (n = 4). There was no.significant asso.iatio. between mo.tality and age gro.p. Five (5) LGAs acco.nted fo. abo.t 60% (29) o. all co.firmed cases. These LGAs co.tribute o.ly 20% to.the to.al po.ulatio. in the State. o.ly 5.6% and 4% o. suspected and co.firmed cases, respectively, had kno.ledge o. co.tact with an infectio.s so.rce. The study described the epidemio.o.y o. Mpo. o.tbreaks between 2017

关键词： Mpo. Epidemio.o.y o.tbreak Surveillance

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Hydro.agnetic Squeezing Nano.luid Flo. between Two.Vertical Plates in Presence o. a Chemical Reactio.

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Jo.rnal o. Applied Mathematics and Physics 2024年第1期12卷 126-146页

作者： benjamin Matur Madit Jackso. K. Kwanza Phineas Ro. Kio.o.a Department o. Mathematics Pan African University Institute of Basic Sciences Technology and Innovation Juja Kenya Department o. Pure and Applied Mathematics Jomo Kenyatta University of Agriculture and Technology Juja Kenya

In this study, Hydro.agnetic Squeezing Nano.luid flo. between two.vertical plates in presence o. a chemical reactio. has been investigated. The go.erning equatio.s were transfo.med by similarity transfo.matio. and the resulting o.dinary differential equatio.s were so.ved by co.lo.atio. metho.. The velo.ity, temperature, co.centratio. and magnetic inductio. pro.iles were determined with help o. vario.s flo. parameters. The numerical scheme was simulated with aid o. MATLAB. The results sho.ed that increasing the squeeze number o.ly bo.sts velo.ity and co.centratio. while lo.ering temperature. Co.versely, increasing the Hartmann number, Reyno.d’s magnetic number, Eckert number and Thermal Grasho. number generally increases temperature but decreases bo.h velo.ity and co.centratio.. Chemical reactio. rate and So.et number so.ely elevate co.centratio. while Schmidt number o.ly reduces it. The results o. this study will be useful in the fields o. o.l and gas industry, plastic pro.essing industries, filtratio., fo.d pro.essing, lubricatio. system in machinery, Micro.luidics devices fo. drug delivery and o.her related fields o. nano.echno.o.y.

关键词： Hydro.agnetic Squeezing Flo. Nano.luid Variable Magnetic Field Chemical Reactio.

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Dynamics o. Plate Equatio.s with Memo.y Driven by Multiplicative No.se o. Bo.nded Do.ains

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Jo.rnal o. Applied Mathematics and Physics 2024年第4期12卷 1492-1521页

作者： Mo.amed Y. A. Bakhet Abdelmajid Ali Dafallah Jing Wang Qiao.hen Ma Fadlallah Mustafa Mo.a Ahmed Eshag Mo.amed Paride o. Lo.ika Makur Mukuac Chino. Scho.l o. Mathematics University of Juba Juba South Sudan Department o. Mathematics Faculty of Petroleum and Hydrology Engineering Alsalam University Almugled Sudan Co.lege o. Mathematics and Statistics Northwest Normal University Lanzhou China Department o. Mathematics and Physics Faculty of Education University of Kassala Kassala Sudan Department o. Mathematics School of Education University of Juba Juba South Sudan

This article examines the dynamics fo. sto.hastic plate equatio.s with linear memo.y in the case o. bo.nded do.ain. We investigate the existence o. so.utio.s and bo.nded abso.bing set by using the unifo.m pullback attracto.s o. the tails estimates, and the asympto.ic co.pactness o. the rando. dynamical system is pro.ed by deco.po.itio. metho., and then we o.tain the existence o. a rando. attracto..

关键词： Plate Equatio.s Rando. Attracto.s Memo.y Term Dynamical Systems

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Effect o. a Nutritio. Educatio. Interventio. o. Fo.d Safety Kno.ledge, Attitudes and Practices o. Mo.hers o. Children under 5 Years in the Peri-Urban Areas o. Bo.o.Dio.lasso. Befo.e and after Study

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Fo.d and Nutritio. Sciences 2024年第5期15卷 401-420页

作者： Alain Hien Jéro.e W. So.é o.ivier o. So.bié Isido.e Trao.é Augustin N. Zeba Geo.ges Anicet o.edrao.o.Ro.and Nâg-Tiero.Meda Institute o. Health Sciences Nazi Boni University Bobo-Dioulasso Burkina Faso Natio.al Institute o. Public Health Muraz Center Bobo-Dioulasso Burkina Faso Research and Teaching Labo.ato.y in Animal Health and Bio.echno.o.y Nazi Boni University Bobo-Dioulasso Burkina Faso Natio.al Center fo. Scientific and Techno.o.ical Research/Institute fo. Health Sciences Research Ouagadougou Burkina Faso Natio.al Center fo. Scientific and Techno.o.ical Research/Institute fo. Health Sciences Research Western Regional Directorate Bobo-Dioulasso Burkina Faso Public Health Nutritio. Unit Department of Public Health and Primary Care Ghent University Ghent Belgium

Backgro.nd: This study assessed the effect o. a nutritio. educatio. interventio.. This interventio. aimed to.impro.e the kno.ledge, attitudes, and practices o. mo.hers o. fo.d safety in the peri-urban areas o. Bo.o.Dio.lasso.in Burkina Faso. Metho.s: A to.al o. 243 mo.hers o. children under 5 years in the peri-urban o. Bo.o.Dio.lasso.were administered the FAo.questio.naire fo. fo.d safety kno.ledge, attitudes, and practices assessment during two.cro.s-sectio.al surveys, befo.e and after the interventio., in January and o.to.er 2017. The interventio. included two.co.po.ents co.sisting o. a theo.etical phase (co.nselling and discussio.) and co.king demo.stratio.s implemented fo. ten mo.ths. To.acco.nt fo. the befo.e-and-after design o. the study, the McNemar’s test was used to.assess the effect o. the interventio. o. fo.d safety KAP o. mo.hers o. children under 5 years. Results: The mean age o. mo.hers was 29 ± 6.2 years and 50.6% o. them were between 20 and 29 years o.d. o.e fo. kno.ledge (co.king tho.o.ghly with, p-value = 0.0001) and ano.her fo. attitudes (perceived benefits o. reheating lefto.ers befo.e eating them, p-value = 0.0001), significantly increased after the interventio.. In terms o. fo.d safety practices, all the indicato.s (cleaning o. dirty surfaces, plates and utensils and sto.age o. perishable fo.ds) significantly increased (all p = 0.0001 Co.clusio.: This study pro.ided so.e evidence o. an effective nutritio. educatio. interventio. fo. impro.ing maternal KAP o. fo.d safety fo. their child’s feeding.

关键词： Nutritio. Educatio. Interventio. Kno.ledge Attitudes and Practices Fo.d Safety Mo.hers o. Children under 5 Years Burkina Faso

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