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Overweight and obesity in young adults with patellofemoral pain:Impact on functional capacity and strength

Journal of Sport and Health Science 2023年第2期12卷 202-211页

作者： Amanda Schenatto Ferreira benjamin FMentiplay bianca Taborda Marcella Ferraz Pazzinatto Fábio Mícolis de Azevedo Danilo de Oliveira Silva Department of Physiotherapy School of Science and TechnologySao Paulo State University(UNESP)Presidente Prudente19060-900Brazil La Trobe Sport and Exercise Medicine Research Centre School of Allied HealthHuman Services and SportLa Trobe UniversityMelbourneVIC 3086Australia

Purpose:This study aimed to(a)investigate the proportion of overweight/obesity in a cohort of young adults with patellofemoral pain(PFP)and(b)explore the association of body mass index(bMI),body fat,and lean mass with functional capacity and hip and knee strength in people with ***:We included a mixed-sex sample of young adults(18-35 years old)with PFP(n=100).Measurements for bMI,percentage of body fat,and lean mass(assessed by bioelectrical impedance)were *** capacity was assessed by the Anterior Knee Pain Scale,plank test,and single-leg hop *** of the knee extensors,knee flexors,and hip abductors was evaluated isometrically using an isokinetic *** proportion of overweight/obesity was calculated based on *** association between bMI,body fat,and lean mass and functional capacity and strength was investigated using partial correlations,followed by hierarchical regression analysis,adjusted for covariates(sex,bilateral pain,and current pain level).Results:A total of 38%of our cohort had their bMI categorized as overweight/*** bMI was associated with poor functional capacity(ΔR^(2)=0.06-0.12,pbody fat was associated with poor functional capacity(ΔR^(2)=0.05-0.15,p≤0.015)and reduced strength(ΔR^(2)=0.15-0.23,pbMI,body fat,and lean mass should be considered in the assessment and management of young people with PFP because it may be detrimental to function and strength.

关键词： body fat distribution body mass index Patellofemoral pain syndrome Torque

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Sex-specific sterility caused by extreme temperatures is likely to create cryptic changes to the operational sex ratio in Drosophila virilis

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Current Zoology 2021年第3期67卷 341-343页

作者： benjamin S.Walsh Natasha L.M.Manimion Tom A.R.Price Steven R.Parratt Institute of Integrative biology University of LiverpoolCrown StreetLiverpoolL697ZBUK

Climate change is increasing the frequency and severity of short-term heat shocks that threaten the persistence of natural ***,most work addressing the evolutionary consequences of anthropogenic environmental change has focused on natural selection,with less attention paid to the impacts on sexual *** conditions under which sexual selection operates is a topic of debate,but a generally observed pattern is that the oper-ational sex ratio(OSR)of a population is key to determining both the extent of competition for fertilizations and the scope for mate choice(Weir et al.2011)

关键词： climate change reproduction sexual selection fertility

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Dynamic response of wind turbine towers in warm permafrost

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Research in Cold and Arid Regions 2014年第5期6卷 423-427页

作者： benjamin Still ZhaoHui (Joey) Yang Simon Evans FuJun Niu Dept.of Civil Engineering University of Alaska Anchorage State Key Laboratory of Frozen Soil Engineering Chinese Academy of Science Alaska Native Tribal Health Center AnchorageAK 99508USA State Key Laboratory of Frozen Soil Engineering Cold and Arid Regions Environmental and Engineering Research InstituteChinese Academy of Sciences

Wind is a great source of renewable energy in western *** winds blow across the barren tundra underlain by warm permafrost in the winter season,when the energy demand is the *** engineering in warm permafrost has always been a challenge in wind energy *** warm permafrost poses engineering issues to design,construction,and operation of wind *** paper describes the foundation design of a wind turbine built in western *** presents a system for response monitoring and load assessment,and data collected from September 2013 to March *** dynamic properties are assessed based on the monitoring data,and seasonal changes in the dynamic properties of the turbine tower-foundation system and likely resonance between the spinning blades and the tower structure are *** analyses of a wind turbine in warm permafrost are valuable for designing or retrofitting of foundations in warm permafrost.

关键词： wind turbine vibration field monitoring warm permafrost

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穷理查智慧书

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作者： (美)本杰明·富兰克林(benjamin Frankin)

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Synthesis of Miktoarm Triblock Copolymers Composed of Ethylene Glycol,L-Lysine and Lactide with Serine as the Centre Linker

Synthesis of Miktoarm Triblock Copolymers Composed of Ethyle...

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4th East-Asian Polymer Conference

作者： benjamin Hsiao benjamin Chu Department of Chemistry Stony brook University Stony BrookNY 11794USA Department of Chemistry Stony brook University Stony BrookNY 11794USA

＜正＞We attempted to prepare miktoarm triblock copolymers composed of ethylene glycol （EG）, L-lysine （Lys） and Iactide （LA） with serine as the centre linker through two different routes. Route A involved in the sequential building-up of poly（ethylene glycol）（PEG）, poly（lactide）（PLA） and poly（N6-carbobenzyloxy-L-lysine）（PLys（Z）） blocks, followed by the removal of carbobenzyloxy （Cbz） group from PLys（Z） block. However, the degradation of PLA block was observed when acid was used in the last step. Route b involved in the

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Oxidized palm oil impairs reproductive functions and architectures in female rats

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Asian pacific Journal of Reproduction 2023年第4期12卷 182-193页

作者： Wankeu-Nya Modeste Kengne Inès T Ateba benjamin S bend Fortune E Djeumeni Ornela N HathoDominique T Ngadjui E Moundipa Paul F Massoma DieudonnéL Dongmo Alain b Watcho Pierre Department of Animal Organisms biology Faculty of ScienceUniversity of DoualaDoualaCameroon Department of Animal Production Faculty of Agronomy and Agricultural SciencesUniversity of DschangDschangCameroon Department of biochemistry Faculty of ScienceUniversity of YaoundéIYaoundéCameroon Department of Animal biology Faculty of ScienceUniversity of DschangDschangCameroon

Objective:To evaluate the effects of three oxidized palm oil diets(OPD)on female rat reproductive ***:Forty-four female Wistar rats presenting five consecutive and regular estrous cycles were divided into 4 *** rats were fed with:a standard diet,70%of standard diet+30%oxidized palm oil diet(OPD1),OPD1+5 g of boiled yolk egg(OPD2)and OPD1+10%sucrose(OPD3)for 125 days,*** the feeding period,morphometric,estrous cycle,sexual behavior,gestation,biochemical and histomorphometric parameters were ***:All OPDs significantly increased abdominal circumference,body mass index and Lee index coupled to an irregularity and lengthening of the estrous *** significantly decreased appetite and consumption behaviours,quantic pregnancy index,fertility rate,implantation sites and index,serum progesterone and high-density lipoprotein levels,increased pre-implantation losses,anti-implantation activities,serum estradiol,triglycerides,total and low-density lipoprotein-cholesterol levels,and impaired brain and ovaries oxidative *** examinations revealed increases in the number of atresic and primary follicles and decreases in secondary,tertiary,Degraaf,total and corpus luteum follicles in ovaries coupled to a neurodegeneration of hypothalamic anteroventral periventricular neurons in the OPD groups compared to the standard diet ***:The three OPDs induce obesity and impair the female reproductive function,especially OPD2 and *** findings contribute to a better understanding of the adverse effects of palm oil bleaching on the reproductive function in female rats,which could be useful in the management of women with obesity-related sexual dysfunction.

关键词： bleached palm oil Reproductive function Anteroventral periventricular nucleus Ovary Estrogen Progesterone Female rat

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Applying reticular synthesis to the design of Cu-based MOFs with mechanically interlocked linkers

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Nano Research 2021年第2期14卷 417-422页

作者： Alexander J.Stirk benjamin H.Wilson Christopher A.O’Keefe Hazem Amame Kelong Zhu Robert W.Schurko Stephen J.Loeb Department of Chemistry and biochemistry University of WindsorWindsorOntarioN9B 3B4Canada Department of Chemistry The University of JordanAmman11942Jordan School of Chemistry Sun Yat-Sen UniversityGuangzhou 510275China Department of Chemistry and biochemistry Florida State UniversityTallahasseeFlorida 32306-4390USA

The concept of“robust dynamics”describes the incorporation of mechanically interlocked molecules(MIMs)into metal-organic framework(MOF)materials such that large amplitude motions(e.g.,rotation or translation of a macrocycle)can occur inside the free volume pore of the *** aid in the preparation of such materials,reticular synthesis was used herein to design rigid molecular building blocks with predetermined ordered structures starting from the well-known MOF *** linkers were synthesized that have a T-shape,based on a triphenylene tetra-carboxylate strut,and their incorporation into Cu(II)-based MOFs was *** single-crystal structures of three new MOFs,UWCM-12(fof),β-UWCM-13(loz),UWCM-14(lil),with naked T-shaped linkers were determined;β-UWCM-13 is the first reported example of the loz topology.A fourth MOF,UWDM-14(lil)is analogous to UWCM-14(lil)but contains a[2]rotaxane ***-temperature,^(2)H solid-state NMR was used to probe the dynamics of a 24-membered macrocycle threaded onto the MOF skeleton.

关键词： reticular chemistry metal-organic frameworks mechanically interlocked molecules rotaxane

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MicroRNA-149 Regulates Proliferation,Migration,and Invasion of Pituitary Adenoma Cells by Targeting ADAM12 and MMP14

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Current Medical Science 2022年第6期42卷 1131-1139页

作者： Zhuo ZHANG Agnes Schäfer benjamin Voellger Jun-wen WANG Ting LEI Christopher Nimsky Jörg W.bartsch Department of Neurosurgery Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Department of Neurosurgery Philipps University MarburgBaldingerstrasseMarburg35033Germany Sino-German Neuro-Oncology Molecular Laboratory Tongji HospitalTongji Medical CollegeHuazhong University of Science and TechnologyWuhan430030China Center for Mind Brainand BehaviorHans-Meerwein-Strasse 6Marburg35032Germany

Objective Pituitary adenomas(PAs)can adapt an aggressive phenotype by invading adjacent brain structures with rapid cellular *** studies demonstrated that excessive expression of metalloproteases ADAM12 and MMP-14 is instrumental for the active proliferation and invasiveness of PA cells in vitro and of tumors in ***,the mechanisms regulating ADAM12 and MMP-14 expression in PAs remain *** Target gene prediction and transcriptomic profiling of invasive *** human PA samples were performed to identify miRNA species potentially involved in the regulation of ADAM12 and *** cellular analyses of miRNA functions,two mouse PA cell lines(AtT20 and TtT/GF)were transfected with miR-149-3p and miR-149-5p,*** effects of miR-149(3p and 5p)on expression levels of ADAM12 and MMP14 were determined by Western blotting followed by an analysis of proliferation and colony formation assays,scratch migration assays,and invasion *** A significant downregulation of miRNA-149 was observed in invasive *** PA(0.32 vs.0.09,Pby at least 40%in both cell *** This study proved that the invasiveness of PA cells is,at least partly,regulated by miRNA-149-dependent expression of ADAM12 and MMP-14.

关键词： pituitary adenoma microRNA miRNA-149 ADAM12 MMP-14 invasion

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Scientific case studies in land-use driven soil erosion in the central United States: Why soil potential and risk concepts should be included in the principles of soil health

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International Soil and Water Conservation Research 2018年第1期6卷 63-78页

作者： benjamin L.Turner Jay Fuhrer Melissa Wuellner Hector M.Menendez barry H.Dunn Roger Gates Texas A&M University-Kingsville Department of AgricultureAgribusinessand Environmental Science700 University Blvd.MSC 228KingsvilleTX 78363USA North Dakota Natural Resource Conservation Service 220 East Rosser AvenuePO Box 1458BismarckND 58502-1458USA University of Nebraska-Kearney Department of BiologyBruner Hall of Science240111th AvenueKearneyNE 68849-1140USA South Dakota State University Department of Natural Resource ManagementBox 2140BBrookingsSD 57007USA South Dakota State University Box 2201BrookingsSD 57007USA University of Georgia 104 S.Thornton Ave.DaltonGA 30720USA

Despite recent improvements in overall soil health gained through conservation agriculture, which has become a global priority in agricultural systems, soil and water-related externalities (e.g., wind and water erosion) continue to persist or worsen. Using an inductive, systems approach, we tested the hypothesis that such externalities persist due to expansion of cultivation onto areas unsuitable for sustained production. To test this hypothesis, a variety of data sources and analyses were used to uncover the land and water resource dynamics underlying noteworthy cases of soil erosion (either wind or water) and hydrological effects (e.g., flooding, shifting hydrographs) throughout the central United States. Given the evidence, we failed to reject the hypothesis that cultivation expansion is contributing to increased soil and water externalities, since significant increases in cultivation on soils with severe erosion limitations were observed everywhere the externalities were documented. We discuss the case study results in terms of land use incentives (e.g., policy, economic, and biophysical), developing concepts of soil security, and ways to utilize case studies such as those presented to better communicate the value of soil and water resource conservation. Incorporating the tenets of soil potential and soil risk into soil health evaluations and cultivation decision-making is needed to better match the soil resource with land use and help avoid more extreme soil and water-related externalities.

关键词： Soil erosion Watershed runoff Soil potential Soil security Externality

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Multi-chromatic silicon nanocrystals

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Light(Science & Applications) 2017年第1期6卷 721-728页

作者： benjamin bruhn benjamin JM brenny Sidoeri Dekker Ilker Doğan Peter Schall Katerina Dohnalová Van der Waals-Zeeman Institute University of AmsterdamScience Park 904Amsterdam 1098 XHThe Netherlands Center for Nanophotonics AMOLFScience Park 104Amsterdam 1098 XGThe Netherlands Department of Applied Physics Eindhoven University of TechnologyP.O.Box 512Eindhoven 5600 MBThe Netherlands Dutch Institute for Fundamental Energy Research(DIFFER) P.O.Box 6336Eindhoven 5600 HHThe Netherlands

Silicon nanocrystals(SiNCs)have great potential to become environmental friendly alternatives to heavy-metal containing nanocrystals for applications including medical imaging,lighting and *** exhibit excellent photostability,non-toxicity and abundant resources,but their often reported inefficient and spectrally limited light emission seriously impair their *** we demonstrate a new method that converts SiNCs into an efficient and robust multi-chromatic ***~15 keV electron-beam irradiation of oxide-capped SiNCs,we introduce several types of color centers into the nanocrystal’s oxide shell with efficient blue,green and red emission bands,together yielding warm-white photoluminescence,even for a single *** centers are not native to the original system and we relate them to known defects in *** in the silica host,however,here the centers are efficiently optically *** further optimization and up-scaling of this method,e-beam irradiated SiNCs can be of great interest as white phosphors for applications such as LEDs.

关键词： cathodoluminscence color center electron beam multi-chromaticity silicon nanocrystals

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