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Empowerment in chronic wound care——exploring the scope for patient contribution

Frontiers of Nursing 2024年第1期11卷 1-16页

作者： benedikt Hackert Ewa Klara Stürmer Ulrich Weger Department of Psychology and Psychotherapy University of Witten/HerdeckeAlfred-Herrhausen-Straße 5058448 WittenGermany Department for Vascular Medicine University Heart and Vascular Center HamburgUniversity Medical Center Hamburg-EppendorfMartinistreet 5220246 HamburgGermany

Objective:In this study,we investigated the concept of empowerment in chronic wound care and propose to facilitate patient control by making use of degrees of freedom(DOF):that is,shaping of everyday wound care tasks initiated by patients and based on their wishes,mostly in terms of patients executing treatment steps,requesting or directing health care professionals to under take changes,or modifications of internal ***:As a first step,we conducted a systematic literature search,followed by an inductive form of qualitative content analysis,which resulted in the identification of 5 dimensions as main elements of empowerment:education and shared decision making,adherence to self-care behaviors,responsibility and control,general call for empowerment,and ***,the latter are noticeably absent in the *** investigate patients'freedom in shaping the wound care process,we conducted a second literature ***:A number of possibilities for patients to influence the wound care process could be identified,but experimental or clinical evidence about their effects is missing,their variety is limited,and they are only inadequately ***:However,DOF should be an indispensable aspect of genuine empowerment,since they allow patients to occupy the role of the agent in the treatment process and give rise to the subjective experience of feeling ***,in the third part,we develop a research proposal on how to investigate and include DOF in the clinical practice of wound ***,limitations about implementations are discussed(e.g.,patients being reluctant to overcome their passive role,resulting in frustration for health care professionals).

关键词： adherence chronic wounds control degrees of freedom empowerment shared decision making

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我国优秀越野滑雪运动员有氧和无氧能力与短距离比赛竞技表现的相关性探究

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首都体育学院学报 2024年第3期36卷 303-312,345页

作者：尚磊史瑞应蔡旭旦 benedikt Fasel 张蓓陈小平清华大学体育部北京100084 中国政法大学社会学院北京102269 南京师范大学体育科学学院江苏南京210023 洛桑联邦理工大学移动分析与测量实验室瑞士1015 国家体育总局冬季运动管理中心北京100044 国家体育总局体育科学研究所运动训练中心北京100061

目的:探究我国优秀越野滑雪运动员短距离比赛竞技表现以及与其有氧、无氧能力的相关关系,其数据和成果对训练和比赛具有重要指导作用。方法:对21名越野滑雪国家集训队男子运动员分别进行有氧、无氧能力和短距离比赛测试;使用GNSS定位系... 详细信息

目的:探究我国优秀越野滑雪运动员短距离比赛竞技表现以及与其有氧、无氧能力的相关关系,其数据和成果对训练和比赛具有重要指导作用。方法:对21名越野滑雪国家集训队男子运动员分别进行有氧、无氧能力和短距离比赛测试;使用GNSS定位系统和计时设备记录短距离比赛中运动员时间、速度和技术等数据;通过典型相关分析方法,评价有氧、无氧能力指标与短距离比赛竞技表现指标的相关关系。结果:1)有氧能力测试中乳酸阈摄氧量、最大摄氧量和总效率指标及无氧能力测试中上肢最大功率、平均功率指标分别与短距离比赛的竞技表现指标密切相关(p<0.05);2)短距离比赛的比赛时间、上坡段时间、平地段时间、G3使用比例、G3最大速度与有氧、无氧能力指标具有较高的相关性(p<0.05)。结论:以测试氧摄取指标为主的有氧能力和以测试上肢最大功率指标为主的无氧能力与越野滑雪短距离比赛竞技表现高度相关;乳酸阈摄氧量、最大摄氧量、总效率等有氧能力指标是影响比赛成绩的重要因素,更高的上肢爆发力水平与更好的短距离比赛竞技表现显著相关。建议:注重发展我国越野滑雪运动员专项技术的有氧能力和上肢峰值功率水平。未来的研究可以通过实验室和雪上环境下进行标准化实验设计,进一步探讨有氧和无氧能力的动态变化对短距离比赛全程和分段竞技表现的直接影响。

关键词：短距离项目有氧能力无氧能力竞技表现

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氙气诱导晚期在体心脏预适应：环氧化酶2的作用

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麻醉与镇痛 2009年第6期5卷 29-36页

作者： Nina C. Weber Jan Fraβdorf Christoph Ratajczak Yvonne Grueber Wolfgang Schlack Markus W. Hollmann benedikt preckel 吴镜湘(译) 徐美英(校) Laboratory of Experimental Intensive Care and Anesthesiology (L.E.I.C.A.) Academic Medical Center (A.M.C.) University of Amsterdam Amsterdam The Netherlands Department of Anesthesiology University Hospital Dusseldorf Germany 不详

背景氙气可诱导大鼠在体心脏的早期心肌预适应，但是否可诱导晚期心肌保护尚不知。环氧化酶2（COX-2）是介导心肌晚期缺血预适应（i-LPC）信号传导的重要介质之一。本文研究氙气是否可诱导晚期预适应（Xe—LPC）以及COX-2活性或表达是... 详细信息

背景氙气可诱导大鼠在体心脏的早期心肌预适应，但是否可诱导晚期心肌保护尚不知。环氧化酶2（COX-2）是介导心肌晚期缺血预适应（i-LPC）信号传导的重要介质之一。本文研究氙气是否可诱导晚期预适应（Xe—LPC）以及COX-2活性或表达是否介导了这种作用。方法雄性Wistar大鼠麻醉后置入冠状动脉阻断器。7天后动物随机分配到5个组，每组8只。i-LPC组通过阻断冠状动脉5分钟来诱发；Xe-LPC组通过吸入70％的氙气15分钟获得。其他大鼠用COX-2抑制剂NS-398（5mg·kg^-1，腹腔内注射）预处理，然后分别使用或不使用Xe-LPC。假手术组的动物不接受缺血预处理或氙气预处理，作为对照组。24小时后所有动物麻醉，收紧冠状动脉阻断器造成心肌缺血25分钟，继而开放再灌注2小时。TTC染色法测定心肌梗死面积。另外还在预处理后不同时间点取心脏，分别用PCR和Westernblot法检测COX-2mRNA及其蛋白表达。结果与对照组相比，缺血预处理组和氙气预处理组均可减少心肌梗死面积（所占百分比分别为：i-LPC组29％±7％，Xe—LPC31％±8％，与对照组比P均〈0．05，对照组为64％±6％）。NS-398可消除氙气诱导的心脏保护作用（该组为61％±6％，与Xe-LPC组比P〈0．05）。COX-2mRNA及其蛋白表达只在i-LPC组有所增加，Xe-LPC组无明显变化。结论氙气诱导晚期心肌预适应，这种作用可以被COX-2抑制剂消除，与缺血预适应相比，氙气诱导的预适应并不增加COX-2mRNA及其蛋白的表达。这一结果表明缺血预适应与氙气诱导的预适应在COX-2调节上存在差别。

关键词：心肌预适应晚期预适应环氧化酶2 在体心脏氙气 COX-2mRNA COX-2抑制剂 Westernblot法

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Towards Realistic Vibration Testing of Large Floor Batteries for Battery Electric Vehicles (BEV)

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Sound & Vibration 2022年第1期56卷 1-19页

作者： benedikt Plaumann Faculty of Engineering and Computer Science Department Automotive and Aeronautical EngineeringHamburg University of Applied Sciences(HAW Hamburg)Hamburg20099Germany

This contribution shows an analysis of vibration measurement on large floor-mounted traction batteries of Battery Electric Vehicles(BEV).The focus lies on the requirements for a realistic replication of the mechanical environments in a testing *** the analysis on global bending transfer functions and local corner bending coherence indicate that neither a fully stiff fixation of the battery nor a completely independent movement on the four corners yields a realistic and conservative test *** contribution will further show what implication these findings have on future vibration&shock testing equipment for large traction ***,it will cover an outlook on how vibration behavior of highly integrated approaches(cell2car)changes the mechanical loads on the cells.

关键词： Battery electric vehicle BEV shock and vibration vehicle floor bending rechargeable energy storage system RESS

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Smooth free-cycle dynamic soaring in unspecified shear wind via quadratic programming

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Chinese Journal of Aeronautics 2022年第7期35卷 19-29页

作者： Haichao HONG benedikt GRüTER Patrick PIPREK Florian HOLZAPFEL Institute of Flight System Dynamics Technical University of MunichGarching D-85748Germany

Harvesting wind energy is promising for extending long-endurance flights,which can be greatly facilitated by a flight technique called dynamic *** presented study is concerned with generating model-based trajectories with smooth control histories for dynamic soaring maneuvers exploiting wind *** desired smoothness is achieved by introducing a trigonometric series parameterization for the controls,which are formulated with respect to the normalized ***,the periodicity of the trigonometric functions is leveraged to facilitate the connection of cycles and streamline the problem *** relying on a specified wind profile,a freefinal-time quadratic programming-based control strategy is developed for the online correction of the flight trajectory,which requires only the instant wind *** and online numerical studies show the trade-off to achieve the smoothness and demonstrate the effectiveness of the proposed method in a varying wind field.

关键词： Dynamic soaring Optimal control Quadratic programming Trajectory generation Trigonometric series

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Ascites and complications: getting to the root of the trouble

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Hepatobiliary Surgery and Nutrition 2023年第1期12卷 124-127页

作者： Mattias Mandorfer benedikt Simbrunner Vienna Hepatic Hemodynamic Lab Division of Gastroenterology and HepatologyDepartment of Internal Medicine IIIMedical University of ViennaViennaAustria

After nearly a decade,the American Association for the Study of Liver Diseases has updated its guidance on the diagnosis,evaluation,and management of ascites and its complications(1).Ascites is the most common first hepatic decompensating event,thereby denoting the transition to from compensated advanced chronic liver disease(cACLD)to decompensated cirrhosis-(literally)a watershed moment in the natural history of liver disease(2).

关键词： Cirrhosis portal hypertension transjugular intrahepatic portosystemic shunt(TIPS) albumin

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Porous insights:IpaH7.8 reveals crystal-clear differences of gasdermins in mice and men

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Signal Transduction and Targeted Therapy 2023年第7期8卷 3209-3210页

作者： Friedrich Alexander von Samson-Himmelstjerna benedikt Kolbrink Stefan Krautwald Department of Nephrology and Hypertension University Hospital Schleswig-Holstein24105 KielGermany

Two recent back-to-back papers published in Nature provide new insights into the structural basis of gasdermin B(GSDMB)targeting by the secreted Shigella virulence effector IpaH7.8,the regulation of GSDMB’s pore-forming pyroptotic activity by alternative splicing,and into the inter-species differences regarding IpaH7.8-mediated inhibition of gasdermin D(GSDMD)activity.

关键词： insight Shigella activity

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不同天气背景下京津冀降水临近外推预报

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应用气象学报 2022年第3期33卷 270-281页

作者：王玉虹 Bica benedikt 河北省气象台石家庄050021 奥地利国家气象局维也纳1190

基于2019—2020年京津冀地区不同天气系统影响下的降水过程,采用交叉相关法和光流法对快速更新多尺度分析和预报综合集成系统(Rapid-refresh Multi-Scale Analysis and Prediction System-Integration,RMAPS_IN)的降水分析产品进行0~2 ... 详细信息

基于2019—2020年京津冀地区不同天气系统影响下的降水过程,采用交叉相关法和光流法对快速更新多尺度分析和预报综合集成系统(Rapid-refresh Multi-Scale Analysis and Prediction System-Integration,RMAPS_IN)的降水分析产品进行0~2 h临近外推预报的批量试验。结果表明:由交叉相关法和光流法计算的两种外推矢量在大小和方向上存在一定差异,直接差异与影响降水的天气系统位置有明显的对应关系,而方向差异受地理位置的影响更明显,台风类降水呈弧形带状分布,低槽冷锋类、低涡类、气旋类、暖切变线类等几类降水均呈西北大东南小的特点;预报效果方面,总体上交叉相关法优于光流法,尤其是预报时效超过30 min以后,各种降水类型的批量检验结果显示交叉相关法的预报评分优于光流法,且预报时效越长、优势越明显,但预报时效为10 min时,光流法在低涡类、台风类、暖切变线类的空报率上优于交叉相关法。此外,基于外推的临近预报方法对京津冀地区台风类降水的预报效果最好,其次为暖切变线类、低涡类、低槽冷锋类、气旋类。

关键词：临近预报交叉相关法光流法 RMAPS_IN

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N-acetyl cysteine alters the genotoxic and estrogenic properties of Alternaria toxins in naturally occurring mixtures

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Emerging Contaminants 2022年第1期8卷 30-38页

作者： Georg Aichinger Dino Grgic Julia Beisl Francesco Crudo benedikt Warth Elisabeth Varga Doris Marko Department of Food Chemistry and Toxicology University of ViennaAustria Department of Health Sciences and Technology ETH ZurichSwitzerland

It is unclear if complex mycotoxin mixtures produced by Alternaria *** estrogenic and/or genotoxic under physiological conditions,particularly considering the co-occurrence with antioxidants in ***,this study focused on enlightening the impact of N-acetyl cysteine(NAC),as a representative antioxidative SH-donor,on the mentioned toxicological endpoints of the signature Alternaria toxins alternariol(AOH),altertoxin-II(ATX-II)and a complex extract(CE)of an Alternaria alternata *** Ishikawa cells as an in vitro model,we monitored alterations in toxin concentrations by LC-MS/MS,estrogenicity by alkaline phosphatase assays,cytotoxicity by sulforhodamine B assays,genotoxicity by single-cell gel electrophoresis and the transcription of selected genes of interest by quantitative realtime *** results indicate that the strong genotoxic effects of epoxide-carrying perylene quinones such as ATX-II are erased in the presence of *** cellular effects of ATX-II/AOH mixtures are dominated by the genotoxicity of the perylene *** this mixture,AOH regained its estrogenicity when coincubated with *** contrast,NAC treatment of an AOH/CE mixture did not result in a recovery of estrogenicity,but in potentiated anti-estrogenic *** findings were in line with gene transcription data,that indicated the aryl hydrocarbon receptor(AhR)to be a prime mediator of Alternaria toxin e induced antagonistic effects towards estrogen receptor *** together,further studies on potential endocrine-disruptive properties of non-genotoxic perylene quinones should be a future research priority in the field of these emerging contaminants.

关键词： Mycotoxin DNA damage Xenoestrogen Combinatory toxicology Food contaminant Mixture effects

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Interband cascade technology for energy-efficient mid-infrared free-space communication

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Photonics Research 2023年第4期11卷 582-590页

作者： PIERRE DIDIER HEDWIG KNÖTIG OLIVIER SPITZ LAURENT CERUTTI ANNA LARDSCHNEIDER ELIE AWWAD DANIEL DIAZ-THOMAS ANBARANOV ROBERT WEIH JOHANNES KOETH benedikt SCHWARZ FRÉDÉRIC GRILLOT LTCI Télécom Paris Institut Polytechnique de ParisPalaiseau 91120France mirSense Centre d’intégration NanoInnovPalaiseau 91120France Institute for Solid State Electronics TU Wien1040 ViennaAustria Currently with CREOL College of Optics and PhotonicsUniversity of Central FloridaOrlandoFlorida 32816USA Institut d’Electronique et des Systèmes Universitéde MontpellierCNRS UMR 5214Montpellier 34000France Nanoplus Nanosystems and Technologies GmbH 97218 GerbrunnGermany Center for High Technology Materials University of New MexicoAlbuquerqueNew Mexico 87106USA

Space-to-ground high-speed transmission is of utmost importance for the development of a worldwide broadband ***-infrared wavelengths offer numerous advantages for building such a system,spanning from low atmospheric attenuation to eye-safe operation and resistance to inclement weather *** demonstrate a full interband cascade system for high-speed transmission around a wavelength of 4.18μ*** low-power consumption of both the laser and the detector in combination with a large modulation bandwidth and sufficient output power makes this technology ideal for a free-space optical communication *** proof-of-concept experiment employs a radio-frequency optimized Fabry–Perot interband cascade laser and an interband cascade infrared photodetector based on a type-II InAs/GaSb *** bandwidth of the system is evaluated to be around 1.5 *** allows us to achieve data rates of 12 Gbit/s with an on–off keying scheme and 14 Gbit/s with a 4-level pulse amplitude modulation *** quality of the transmission is enhanced by conventional pre-and post-processing in order to be compatible with standard error-code correction.

关键词： communication system free

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