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Prognostic value of a nomogram model for postoperative liver metastasis of colon cancer

World Journal of Gastrointestinal Surgery 2024年第4期16卷 1055-1065页

作者： De-Xin Cheng kang-Di Xu Han-Bo liu Yi liu Department of Interventional Medicine Zhejiang Provincial People’s Hospital(Affiliated People’s HospitalHangzhou Medical College)Hangzhou 310014Zhejiang ProvinceChina General Surgery Cancer CenterDepartment of Vascular SurgeryZhejiang Provincial People’s Hospital(Affiliated People’s HospitalHangzhou Medical College)Hangzhou 310014Zhejiang ProvinceChina

BACKGROUND Colon cancer is one of the most common malignant tumors of the digestive *** metastasis after colon cancer surgery is the primary cause of death in patients with colon *** To construct a novel nomogram model including various factors to predict liver metastasis after colon cancer *** We retrospectively analyzed 242 patients with colon cancer who were admitted and underwent radical resection for colon cancer in Zhejiang Provincial People’s Hospital from December 2019 to December *** were divided into liver metastasis and non-liver metastasis ***,age,and other general and clinicopathological data(preoperative blood routine and biochemical test indexes)were *** risk factors for liver metastasis were analyzed using singlefactor and multifactorial logistic regression.A predictive model was then constructed and evaluated for *** Systemic inflammatory index(SII),C-reactive protein/albumin ratio(CAR),red blood cell distribution width(RDW),alanine aminotransferase,preoperative carcinoembryonic antigen level,and lymphatic metastasis were different between groups(Pbenefits for a larger threshold range than those in extreme cases,indicating that the model is *** Liver metastases after colorectal cancer surgery could be well predicted by a nomogram based on the SII,CAR,and RDW.

关键词： Systemic immunoinflammatory index C-reactive protein/albumin ratio Erythrocyte distribution width Colon cancer Liver metastasis Novel nomogram model

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Unidirectional transport of both wettable and nonwettable liquids on an asymmetrically concave structured surface

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Fundamental Research 2024年第3期4卷 557-562页

作者： Zhongxue Tang kang Luan Bojie Xu Huan liu Research Institute for Frontier Science School of PhysicsBeihang UniversityBeijing 100191China Key Laboratory of Bio-Inspired Smart Interfacial Science and Technology of Ministry of Education School of ChemistryBeihang UniversityHaidian DistrictBeijing 100191China

Unidirectional liquid transport(UDLT)has been widely used in various fields as an important process for transferring both mass and ***,UDLT driven by a structural gradient has been witnessed for a long time only in wettable *** nonwettable liquids,UDLT can hardly proceed merely by a structural ***,we propose an asymmetrically concave structured surface(AMC-surface),featuring tip-to-base periodically arranged pyramid-shaped concave structures with a certain degree of overlap,which enables the UDLT of both wettable and nonwettable *** wettable liquids,the capillary force along each corner leads to the UDLT pointing toward the base side of the concave pyramid,while for nonwettable liquids,the UDLT is attributable to the static liquid pressure overwhelming the repulsive Laplace pressure induced by the asymmetric grooves and overlapping *** a result,both wettable and nonwettable liquids transport spontaneously and unidirectionally on the AMC-surface with no energy ***,the concave structure endows good mechanical stability and can be easily prepared using a facile nail-punching approach over a large *** also demonstrated its application in a continuous chemical reaction in a confined *** envision that the unique UDLT behavior on the as-developed AMC-surface will shed new light on the programmable manipulation of various liquids.

关键词： Unidirectional liquidtransport Asymmetrically concave structure Capillary force Laplace pressure Wettability

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Exploring charge and spin fluctuations in infinite-layer cuprate SrCuO_(2)from a phonon perspective

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Science China(Physics,Mechanics & Astronomy) 2024年第8期67卷 159-167页

作者： Xin Du Pei-Han Sun ben-Chao Gong Jian-Feng Zhang Zhong-Yi Lu Kai liu Department of Physics and Beijing Key Laboratory of Opto-electronic Functional Materials&Micro-nano Devices Renmin University of ChinaBeijing 100872China Department of Physics School of ScienceJiangsu University of Science and TechnologyZhenjiang 212100China Institute of Physics Chinese Academy of SciencesBeijing 100190China Key Laboratory of Quantum State Construction and Manipulation(Ministry of Education) Renmin University of ChinaBeijing 100872China

The infinite-layer cuprate ACu O_(2)(A=Ca,Sr,Ba)possesses the simplest crystal structure among numerous cuprate superconductors and can serve as a prototypical system to explore the unconventional *** on the first-principles electronic structure calculations,we have studied the electronic and magnetic properties of the infinite-layer cuprate SrCuO_(2)from a phonon *** find that interesting fluctuations of charges,electrical dipoles,and local magnetic moments can be induced by the atomic displacements of phonon modes in SrCuO_(2)upon the hole *** all optical phonon modes of SrCuO_(2)in the antiferromagnetic Néel state,only the A_(1g)mode that involves the full-breathing O vibrations along the Cu-O bonds can cause significant fluctuations of local magnetic moments on O atoms and dramatic charge redistributions between Cu and O ***,due to the atomic displacements of the A_(1g)mode,both the charge fluctuations on Cu and the electrical dipoles on O show a dome-like evolution with increasing hole doping,quite similar to the experimentally observed behavior of the superconducting T_(c);in comparison,the fluctuations of local magnetic moments on O display a monotonic enhancement along with the hole *** analyses indicate that around the optimal doping,there exists a large softening in the frequency of the A_(1g)phonon mode and a van Hove singularity in the electronic structure close to the Fermi level,suggesting potential electron-phonon *** work reveals the important role of the full-breathing O phonon mode playing in the infinite-layer SrCuO_(2),which may provide new insights in understanding the cuprate superconductivity.

关键词： first-principles calculations cuprate superconductors phonon charge and spin fluctuations

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Preparation and properties of high-energy-density aluminum/boroncontaining gelled fuels

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Chinese Journal of Chemical Engineering 2024年第1期65卷 230-242页

作者： Yi Chen kang Xue Yang liu Lun Pan Xiangwen Zhang Ji-Jun Zou Key Laboratory for Green Chemical Technology of the Ministry of Education School of Chemical Engineering and TechnologyTianjin UniversityTianjin 300072China Collaborative Innovative Center of Chemical Science and Engineering(Tianjin) Tianjin 300072China Haihe Laboratory of Sustainable Chemical Transformations Tianjin 300192China Zhejiang Institute of Tianjin University Ningbo 315201China

Energetic nanofluid fuel has caught the attention of the field of aerospace liquid propellant for its high energy density(HED), but it suffers from the inevitable solid-liquid phase separation problem. To resolve this problem, herein we synthesized the high-Al-/B-containing(up to 30%(mass)) HED gelled fuels, with low-molecular-mass organic gellant Z, which show high net heat of combustion(NHOC), density, storage stability, and thixotropic properties. The characterizations indicate that the application of energetic particles to the gelled fuels obviously destroys their fibrous network structures but can provide the new particle-gellant gelation microstructures, resulting in the comparable stability between 1.0%(mass) Z/JP-10 + 30%(mass) Al or B and pure JP-10 gelled fuel. Moreover, the gelled fuels with high-content Al or B exhibit high shear-thinning property, recovery capability, and mechanical strength, which are favorable for their storage and utilization. Importantly, the prepared 1.0%(mass) Z/JP-10 + 30%(mass) B(or 1.0%(mass) Z/JP-10 + 30%(mass) Al) shows the density and NHOC 1.27 times(1.30) and 1.43 times(1.21)higher than pure JP-10, respectively. This work provides a facile and valid approach to the manufacturing of HED gelled fuels with high content of energetic particles for gel propellants.

关键词： Gelled fuels Energetic aluminum/boron Low-molecular-mass organic gellant Fuel property

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Impact of effective stress on permeability for carbonate fractured-vuggy rocks

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Journal of Rock Mechanics and Geotechnical Engineering 2024年第3期16卷 942-960页

作者： Ke Sun Huiqing liu Juliana Y.Leung Jing Wang Yabin Feng Renjie liu Zhijiang kang Yun Zhang State Key Laboratory of Petroleum Resources and Prospecting China University of PetroleumBeijing102249China School of Mining&Petroleum Engineering University of AlbertaEdmontonT6G 1H9Canada SINOPEC Petroleum Exploration and Production Research Institute Beijing100083China

To gain insight into the flow mechanisms and stress sensitivity for fractured-vuggy reservoirs,several core models with different structural characteristics were designed and fabricated to investigate the impact of effective stress on permeability for carbonate fractured-vuggy rocks(CFVR).It shows that the permeability performance curves under different pore and confining pressures(*** stress conditions)for the fractured core models and the vuggy core models have similar change *** ranges of permeability variation are significantly wider at high pore pressures,indicating that permeability reduction is the most significant during the early stage of development for fractured-vuggy *** each obtained effective stress coefficient for permeability(ESCP)varies with the changes in confining pressure and pore pressure,the effective stresses for permeability of four representative CFVR show obvious nonlinear characteristics,and the variation ranges of ESCP are all between 0 and ***,a comprehensive ESCP mathematical model considering triple media,including matrix pores,fractures,and dissolved vugs,was *** is proved theoretically that the ESCP of CFVR generally varies between 0 and ***,the regression results showed that the power model ranked highest among the four empirical models mainly applied in stress sensitivity characterization,followed by the logarithmic model,exponential model,and binomial *** concept of“permeability decline rate”was introduced to better evaluate the stress sensitivity performance for CFVR,in which the one-fracture rock is the strongest,followed by the fracture-vug rock and two-horizontalfracture rock;the through-hole rock is the *** general,this study provides a theoretical basis to guide the design of development and adjustment programs for carbonate fractured-vuggy reservoirs.

关键词： Effective stress Permeability Carbonate fractured-vuggy rocks Structure characteristics Stress sensitivity

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3-Epi-betulinic acid 3-O-β-D-glucopyranoside(eBAG)induces autophagy by activation of AMP-activated protein kinase in hepatocellular carcinoma

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Food Science and Human Wellness 2024年第3期13卷 1453-1464页

作者： Mengjie liu Xuqiang liu Kaiyue He Yongping Jian Yujia Li Jinrong Guo Jingyu Yang Zhixiang Xu Wenyi kang School of Life Sciences Henan UniversityKaifeng 475004China National R&D Center for Edible Fungus Processing Technology Henan UniversityKaifeng 475004China Joint International Research Laboratory of Food&Medicine Resource Function Kaifeng 475004China Shenzhen Research Institute of Henan University Shenzhen 518000China

3-Epi-betulinic acid 3-O-β-D-glucopyranoside(eBAG)is a pentacyclic triterpene mainly distributed in food and medicinal plants,which exhibits various pharmacological ***,whether these functions are attributed to eBAG or additional components in these plants remain ***,we report that eBAG exerted an inhibitory activity against hepatocellular carcinoma and esophageal cancer *** induced non-apoptotic cell death in hepatocellular carcinoma *** eBAG-induced cell death was inhibited by knock-down of autophagy related gene(ATG)5 and ATG7,by administration of 3-methyladenine,a selective autophagy inhibitor that suppresses phosphoinositide 3-kinase(PI3K),and by chloroquine,a classic autophagy flux *** demonstrated that eBAG induced an autophagy-mediated cell *** of eBAG mimicked cellular bioenergetics depletion leading to the reduction of intracellular ATP,activation of AMP-activated protein kinase(AMPK),and inhibition of ***-treatment with compound C,an AMPK inhibitor,abrogated cell death induced by *** further validated the anti-tumor effect of eBAG in the murine xenograft model of hepatocellular carcinoma and found that eBAG treatment promoted the induction of autophagy and reduction of tumor growth in *** a functional food ingredient,eBAG is a potential therapeutic agent for the treatment of hepatocellular carcinoma and esophageal cancer.

关键词： eBAG Autophagy ATP AMPK Hepatocellular carcinoma

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Hierarchical Reduced Graphene Oxide-MnO_(2)@Polypyrrole Coaxial Nanotube Composite Hydrogel as a Potential Adsorbent for Cr(Ⅵ)Removal

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Journal of Wuhan University of Technology(Materials Science) 2024年第5期39卷 1287-1293页

作者： liu ben XU Yaowei TONG Yuxing WANG Ziwei liu Zhichang YAN Qunshan JI Jiayou GAO Song LI Shaoping China Tobacco Hubei Industrial Co. LtdWuhan 430040China Hubei Xinye Reconstituted Tobacco Development Co. Ltd.Wuhan 430056China Applied Technology Research of Reconstituted Tobacco Hubei Province Key Laboratory Wuhan 430040China School of Materials Science and Engineering Wuhan Institute of TechnologyWuhan 430205China Hubei Three Gorges Laboratory Yichang 443008China

A hierarchical reduced graphene oxide-MnO_(2)@polypyrrole coaxial nanotube composite hydrogel was prepared via oxidative polymerization of pyrrole in the presence of MnO_(2)nanotubes,followed by the hydrothermal treatment of graphene oxide and MnO_(2)@polypyrrole coaxial *** stable composite hydrogel with a hierarchical network was composed of one-dimensional MnO_(2)@polypyrrole coaxial nanotube and two-dimensional graphene nanosheet and characterized by scanning electron microscope,Fourier transform infrared spectroscopy,X-ray diffraction,Brunauer-Emmett-Teller surface,and X-ray photoelectron spectroscopy *** composite hydrogel can be used as an efficient adsorbent for Cr(Ⅵ)removal due to the synergistic interaction between graphene and MnO_(2)@polypyrrole and the hierarchical structure of the ***,the composite hydrogel is easily separated because of its stable monolith,and it is reusable(76.8%of removal ability remaining after five adsorption-desorption cycles).The simple fabrication and cost-effective separation process together with the excellent absorption performance endow the composite hydrogel with great potential for practical wastewater treatment.

关键词： hydrogel polypyrrole MnO_(2) graphene Cr(Ⅵ)removal

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Lithium isotopic fractionation in minerals from pegmatites: Perspective of crystal chemistry

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Journal of Earth Science 2024年

作者： Shan-Ke liu ben-xun Su Key Laboratory of Mineral Resources， Institute of Geology and Geophysics， Chinese Academy of Sciences

Lack of information regarding lithium (Li) crystal chemistry in numerous minerals， especially those containing trace amounts of Li (ranging from few to tens of ppm)， limits our understanding of Li isotopic fractionation in pegmatites. In this study， we examined the Li isotopic composition and Li content in various Li-poor (e.g.， quartz or feldspar) together with Li-rich (sopdumene or lepidolite) mineral phases within granitic pegmatites. We compiled a comprehensive dataset， encompassing a broad spectrum of Li contents (ranging from a few to tens of thousands of ppm) and Li isotopic values (-8‰ to 41‰). The minerals exhibited distinct Li isotopic signatures. Specifically， elbaite and beryl showed the highest values， while biotite displayed a negative average. Compared to individual minerals， whole rocks demonstrated lower Li isotopic values， with pegmatites exhibiting the highest and non-granitic pegmatite wall rocks showing the lowest. Our study also uncovered a clear "V" shape relationship between Li isotopic values and logarithm of Li content， with different mineral groups occupying specific regions within this shape. Furthermore， a significant correlation was observed between average Li isotopic values and Li-O(OH， F) bond lengths in various minerals. These discoveries underscore the crucial role of crystal chemistry in shaping the Li isotopic behavior in pegmatites from a statistical perspective.

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Stabilizing zinc anode using zeolite imidazole framework functionalized separator for durable aqueous zinc-ion batteries

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Journal of Energy Chemistry 2024年第3期90卷 23-31,I0003页

作者： Weisong Zhang Xinyan Zhu Ling kang Ziyu Peng Jing Zhu Liang Pan Lei Dai Shude liu Ling Wang Yongguang liu Zhangxing He School of Chemical Engineering North China University of Science and TechnologyTangshan 063009HebeiChina Shanghai Key Laboratory of Multidimensional Information Processing East China Normal UniversityShanghai 201620China College of Textiles Donghua UniversityShanghai 201620China

Aqueous zinc-ion batteries(AZIBs) hold great promise as a viable alternative to lithium-ion batteries owing to their high energy density and environmental ***,AZIBs are consistently plagued by the formation of zinc dendrites and concurrent side reactions,which significantly diminish their overall service life,In this study,the glass fiber separator(GF) is modified using zeolite imidazole salt framework-8(ZIF-8),enabling the development of efficient ***-8,which is abundant in nitrogen content,efficiently regulates the desolvation of [Zn(H_(2)O)_(6)]^(2+) to inhibit hydrogen ***,it possesses abundant nanochannels that facilitate the uniform deposition of Zn~(2+) via a localized action,thereby hindering the formation of *** insulating properties of ZIF-8 help prevent Zn^(2+) and water from trapping electron reduction at the layer surface,which reduces corrosion of the zinc ***,ZIF-8-GF achieves the even transport of Zn^(2+) and regulates the homogeneous deposition along the Zn(002) crystal surface,thus significantly enhancing the electrochemical performance of the AZIBs,In particular,the Zn|Zn symmetric cell with the ZIF-8-GF separator delivers a stable cycle life at0.5 mA cm^(-2) of 2300 *** Zn|ZIF-8-GF|MnO_(2) cell exhibits reduced voltage polarization while maintaining a capacity retention rate(93.4%) after 1200 cycles at 1.2 A g^(-1) The unique design of the modified diaphragm provides a new approach to realizing high-performance AZIBs.

关键词： Aqueous zinc-ion batteries Separators modifications ZIF-8 Zn deposition Dendrite-free

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High-quality ghost imaging based on undersampled natural-order Hadamard source

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Chinese Physics B 2024年第9期33卷 404-411页

作者： kang liu Cheng Zhou Jipeng Huang Hongwu Qin Xuan liu Xinwei Li Lijun Song School of Electronic Information Engineering Changchun UniversityChangchun 130022China School of Physics Northeast Normal UniversityChangchun 130024China College of Electronic and Information Engineering Changchun University of Science and TechnologyChangchun 130022China Jilin Engineering Laboratory for Quantum Information Technology Jilin Engineering Normal UniversityChangchun 130052China Changchun Institute of Technology Changchun 130012China

Improving the speed of ghost imaging is one of the main ways to leverage its advantages in sensitivity and imperfect spectral regions for practical *** of the proportional relationship between image resolution and measurement time,when the image pixels are large,the measurement time increases,making it difficult to achieve real-time ***,a high-quality ghost imaging method based on undersampled natural-order Hadamard is *** method uses the characteristics of the Hadamard matrix under undersampling conditions where image information can be fully obtained but overlaps,as well as deep learning to extract aliasing information from the overlapping results to obtain the true original image *** conducted numerical simulations and experimental tests on binary and grayscale objects under undersampling conditions to demonstrate the effectiveness and scalability of this *** method can significantly reduce the number of measurements required to obtain high-quality image information and advance application promotion.

关键词： ghost imaging natural-order Hadamard deep learning

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