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Subsurface Damage in Scratch Testing of Potassium Dihydrogen Phosphate Crystal

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Chinese Journal of Mechanical Engineering 2009年第1期22卷 15-20页

作者： WANG ben wu Dongjiang GAO Hang KANG Renke GUO Dongming Key Laboratory for Precision and Non-traditional Machining Technology of Ministry of Education Dalian University of Technology Dalian 116024 China

Potassium dihydrogen phosphate （KDP） is an important electro-optic crystal, often used for frequency conversion and Pockels cells in large aperture laser systems. To investigate the influence of anisotropy to the depth of subsurface damage and the profiles of cracks in subsurface of KDP crystal, an experimental study was made to obtain the form of subsurface damage produced by scratches on KDP crystal in [100], [120] and [110] crystal directions on （001） crystal plane. The results indicated that there were great differences between depth and crack shape in different directions. For many slip planes in KDP, the plastic deformation and cracks generated under pressure in the subsurface were complex. Fluctuations of subsurface damage depth at transition point were attributed to the deformation of the surface which consumed more energy when the surface deformation changed from the mixed region of brittle and plastic to the complete brittle region along the scratch. Also, the process of subsurface damage from shallow to deep, from dislocation to big crack in KDP crystal with the increase of radial force and etch pit on different crystal plane were obtained. Because crystallographic orientation and processing orientation was different, etching pits on （100） crystal plane were quadrilateral while on （110） plane and （120） plane were trapezoidal and triangular, respectively.

关键词： potassium dihydrogen phosphate (KDP) crystal scratch subsurface damage

Syntheses and Crystal Structures of Cobalt(II) Chloride Complexes of 1,3-Bis(pyridyl-4-ylthio)propan-2-one

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Chinese Journal of Structural Chemistry 2006年第5期25卷 511-516页

作者： wu ben-Lai wu Ming-Yan GONG Ya-Qiong CHEN Bai-Quan HONG Mao-Chun State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter The Chinese Academy of Sciences Fuzhou Fujian 350002 China

Reactions of 1,3-bis（pyridyl-4-ylthio）propan-2-one L and COCl2·6H2O under different conditions gave two new cobalt（Ⅱ）-chloride-L complexes with distinct structures. Complex [Co（L）2Cl2]·0.5CH3OH}n 1 prepared by solvothermal treatment is a 3D network, whereas complex {[Co3（L）2Cl6（DMF）4]·2CH3OH·H2O} 2 obtained in DMF-diethyl ether system is a discrete acyclic trimer. Crystal data for 1： space group lbca, a = 15.993（4）, b = 18.454（5）, c = 21.506（6）A, V= 6347（3） ,A^3, Z = 8, Dc = 1.462 g/cm^3,μ = 1.005 mm^-1, F（000） = 2864, C26.5H26Cl2CoN4O2.5S4, Mr = 698.58, the final R = 0.0499 and wR = 0.1024. Crystal data for 2： space group P1^-, a = 9.9177（6）, b = 11.0871 （4）, c = 15.5490（12） ,A, α = 83.1834（14）,β = 88.910（13）, γ = 71.096（ 11 ）°, V = 1605.8（2） A^3, Z = 1, Dc = 1.362 g/cm^3,μ= 1.194 mm^-1, F（000） = 677, C40H62Cl6Co3N8O9S4, Mr = 1316.71, the final R = 0.0666 and wR =0.1575.

关键词： cobalt chloride complex 1,3-bis(pyridyl-4-ylthio)propan-2-one crystal structure

Investigating the influence of monosodium L-glutamate on brain responses via scalp-electroencephalogram(scalp-EEG)

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Food Science and Human Wellness 2022年第5期11卷 1233-1239页

作者： ben wu Xirui Zhou Imre Blank Yuan Liu Department of Food Science&Technology School of Agriculture and BiologyShanghai Jiaotong UniversityShanghai 200240China Zhejiang Yiming Food Co. Ltd.Wenzhou 325400China

As the relevance between left and right brain neurons when transmitting electrical signals of umami taste is unknown,the aim of this work was to investigate responsive regions of the brain to the umami tastant monosodium glutamate(MSG)by using scalp-electroencephalogram(EEG)to identify the most responsive brain regions to *** concentrations of MSG(0.05,0.12,0.26 g/100 mL)were provided to participants for tasting while recoding their responsive reaction times and brain *** results indicated that the most responsive frequency to MSG was at 2 Hz,while the most responsive brain regions were T4 CzA2,F8 CzA2,and Fp2 ***,the sensitivity of the brain to MSG was significantly higher in the right brain *** study shows the potential of using EEG to investigate the relevance between different brains response to umami taste,which contributes to better understanding the mechanism of umami perception.

关键词： Umami Taste Monosodium glutamate Electroencephalogram Brain

Syntheses and Crystal Structures of Two 3D Zinc(II) Compounds Involving Coordination and Hydrogen Bonds

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Chinese Journal of Structural Chemistry 2006年第5期25卷 527-532页

作者： CHEN Bai-Quan HAN Lei wu ben-Lai wu Ming-Yan HUANG You-Gui HONG Mao-Chun State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter The Chinese Academy of Sciences Fuzhou Fujian 350002 China Graduate School of the Chinese Academy of Sciences Beijing 100039 China

Two zinc（Ⅱ） compounds, [Zn（L）（H2O）2]n 1 and [Zn（4,4＇-bpy）（H2O）4]（L） 2 （H2L = trans,trans-1,3 butadiene 1,4-dicarboxylic acid）, were synthesized by hydrothermal methods and characterized by single-crystal X-ray diffraction analyses. Compound 1 crystallizes in monoclinic, space group C2/c with a=15.4970（16）, b = 5.4976（6）, c = 10.7113（12） A, β=96.298（6）°, C6H8O6Zn, Mr = 241.50, V = 907.06（17） A^3, Z = 4, D, = 1.768 g/cm^3, F（000） = 488,μ = 2.703 mm^-1, S = 1.060, the final R = 0.0256 and wR = 0.0660 for 968 observed reflections with Ⅰ 〉 2σ（Ⅰ）. Compound 2 crystallizes in triclinic, space group P1^- with a = 6.915（2）, b = 7.166（2）, c = 10.363（3） A, α = 73.250（4）, β = 84.429（4）, γ = 61.605（3）°, C16H2ON2O8Zn, Mr = 433.70, V = 432.1 （2） A^3, Z = 1, D, = 1.667 g/cm^3, F（000） = 224 and μ= 1.471 mm^-1, S = 1.118, the final R = 0.0486 and wR = 0.1077 for 1352 observed reflections with Ⅰ〉 2σ（Ⅰ）. Upon using the assembly strategy of combination of coordination polymer chains with intermolecular hydrogen bonds, three-dimensional frameworks of complexes 1 and 2 were formed.

关键词： Zn(Ⅱ) coordination polymer hydrogen bonds crystal structure

Syntheses and Crystal Structures of Two Complexes with 3-(3-Pyridyl)acrylic Acid

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Chinese Journal of Structural Chemistry 2005年第10期24卷 1123-1128页

作者： HUANG You-Gui ZHOU You-Fu wu ben-Lai HAN Lei YUAN Da-Qiang LOU ben-Yong HONG Mao-Chun State Key Laboratory of Structural Chemistry Fujian Institute of Research on the Structure of Matter The Chinese Academy of Sciences Fuzhou Fujian 350002 China

The reaction of 3-（3-pyridyl）acrylic acid （H（3-PYA）） with Co（NO3）2.6H2O or MnCl2.4H2O yielded two new complexes： [Co（3-PYA）2（H2O）4.H2O] 1 and [Mn（3-PYA）2（H2O）4] 2. Complex 1 crystallizes in monoclinic, space group C2/c with a = 9.9473（12）, b = 13.7227（16）, c = 14.7376（18） A, β = 99.043（2）°, V = 1986.7（4） A^3, Z = 4, Dc= 1.549 g/cm^3,μ = 0.921 mm^-1, F（000） = 964, R = 0.0786 and wR = 0.1443. Six types of hydrogen bonds and π-π packing interactions connect the mononuclear units [Co（Ⅱ）（3-PYA）2（H2O）4·H2O] into a three-dimensional supramolecular architecture. Complex 2 crystallizes in monoclinic, space group P21/n with a = 11.3630（16）, b = 7.0346（10）, c = 12.1365（18） A, β = 112.545（3）°, V = 896.0（2） A^3, Z = 2, D, = 1.997 g/cm^3,μ = 0.785 mm^-1, F（000） = 438, R = 0.0787 and wR = 0.1550. The discrete entity Mn（Ⅱ）（3-PYD）2（H2O）4 is extended into a 3-D supramolecular architecture by four kinds of hydrogen bonds.

关键词： crystal structure hydrogen bonding 3-(3-pyridyl)acrylic acid cobalt manganese

Photonic analog signal processing and neuromorphic computing[Invited]

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Chinese Optics Letters 2024年第3期22卷 123-136页

作者： James Garofolo ben wu Department of Electrical and Computer Engineering Rowan UniversityGlassboroNJ 08028USA

In this review paper,we discuss the properties and applications of photonic computing and analog signal *** computational circuits have large operation bandwidth,low power consumption,and fine frequency control,enabling a wide range of application-specific computational techniques that are impossible to implement using traditional electrical and digital hardware *** advantages are illustrated in the elegant implementation of optical steganography,the real-time blind separation of signals in the same bandwidth,and the efficient acceleration of artificial neural network *** working principles and use of photonic circuits for analog signal processing and neuromorphic computing are reviewed and notable demonstrated applications are highlighted.

关键词： blind-source separation optical steganography neuromorphic photonics

Application of human bone marrow-derived mesenchymal stem cells in the treatment of radiation-induced gastrointestinal syndrome

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Science China(Life Sciences) 2014年第12期57卷 1177-1182页

作者： YANG Chao DAI Wei Min CHEN Hai Xu wu ben Yan Gastrointestinal Department of Southern Building General Hospital of Chinese PLA Department of Thoracic Surgery General Hospital of Chinese PLA Institute of Gerontology and Geriatrics General Hospital of Chinese PLA

Nuclear accidents and terrorism present a serious threat for mass *** or intended radiation exposure leads to radiation-induced gastrointestinal(GI)***,currently there are no approved medical countermeasures for GI ***,developing novel treatments for GI syndrome is *** stem cells(MSCs)derived from bone marrow are a subset of multipotent adult somatic stem cells that have the ability to undergo self-renewal,proliferation and pluripotent *** have advantages over other stem cells;they can be easily isolated from patients or donors,readily expanded ex vivo,and they possess reparative and immunomodulatory ***,MSCs have been shown to be powerful tools in gene therapy and can be effectively transduced with vectors containing therapeutic ***,the therapeutic potential of MSCs has been brought into the spotlight for the clinical treatment of GI *** this review,we discuss the possible role of MSCs in radiation-induced GI syndrome.

关键词： mesenchymal stem cells radiation-induced gastrointestinal syndrome treatment

Suppressive effect of Aurantii Fructus Immaturus and Atractylodis Macrocephalae Rhizoma on glutamic acid-induced autophagy of interstitial cells of Cajal

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Journal of Integrative Medicine 2020年第4期18卷 334-343页

作者： Shuai Yan Yin-zi Yue Ming-ming Sun ben-sheng wu Xiao-peng Wang Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica School of PharmacyNanjing University of Chinese MedicineNanjing 210023Jiangsu ProvinceChina Department of Anorectal Surgery Suzhou TCM HospitalNanjing University of Chinese MedicineSuzhou 215009Jiangsu ProvinceChina First Clinical Medical School Nanjing University of Chinese MedicineNanjing 210023Jiangsu ProvinceChina

Objective:To investigate the effects of Aurantii Fructus Immaturus(Zhishi,ZS)and Atractylodis Macrocephalae Rhizoma(Baizhu,BZ)-containing serum on glutamate-induced autophagy in rat colonic interstitial cells of Cajal(ICCs)and to analyze the underlying ***:Rat colonic ICCs cultured in vitro were identified by fluorescence and then stimulated with glutamic acid(5 mmol/L)for 24 h to establish a cell model of *** cells were then treated with different concentrations of ZSBZ-containing serum or rat *** viability of the ICCs was detected with cell counting kit-8 assays,and cell apoptosis rates were examined with flow *** ultrastructure and autophagosomes in the ICCs were observed using transmission electron *** effects of ZSBZ-containing serum on apoptosis-associated mediators were assessed by Western blotting and real-time quantitative polymerase chain *** addition,microtubule-associated protein light chain 3(LC3),p-phosphoinositide 3-kinase(p-PI3 K),p-Akt and p-mammalian target of rapamycin(pm TOR)expression was detected via Western blotting ***:Compared to those in the model group,ICC viability and apoptosis rates were significantly increased by ZSBZ-containing serum(Pbeneficial effect may be mediated by a reduction in autophagy via inhibition of the PI3 K/Akt/mTOR pathway.

关键词： Herbal medicine,Chinese Autophagy Phosphoinositide 3-kinase Signal pathway

Therapeutic plasma exchange and continuous renal replacement therapy for severe hyperthyroidism and multi-organ failure:A case report

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World Journal of Clinical Cases 2019年第4期7卷 500-507页

作者： Jun-Hui Ba ben-Quan wu Yan-Hong Wang Yun-Feng Shi Department of Medical Intensive Unit the Third Affiliated Hospital of Sun Yat-Sen University

BACKGROUND Severe hyperthyroidism is a life-threatening exacerbation of thyrotoxicosis,characterized by high fever and multiorgan failure. The most common medical treatments are administration of antithyroid drugs and radioactive iodine, and thyroidectomy. In some patients, antithyroid therapy is limited due to serious adverse effects or failure to control disease progression. In some extreme cases,such as thyroid storm, conventional therapy alone does not yield effective and rapid improvement before the development of multiorgan *** SUMMARY This report describes a Chinese patient with severe hyperthyroidism accompanied by multiorgan failure, who was transferred to the medical intensive care unit of our hospital. The patient presented with palpitations, vomiting,diarrhea, and shortness of breath for a week. Laboratory tests showed elevation of thyroid hormones. Hepatic failure occurred with high aminotransferase levels and jaundice. Given her abnormal liver function and medication history, we could not exclude diagnosis of propylthiouracil-induced hepatic ***, she also suffered from heart failure. Therapeutic plasma exchange(commonly known as TPE) and continuous renal replacement therapy(commonly known as CRRT) were used as life-saving therapy, which resulted in notable improvement of clinical symptoms and laboratory *** Combined TPE and CRRT are safe and effective for patients with hyperthyroidism and multiorgan failure.

关键词： Severe hyperthyroidism Propylthiouracil-induced hepatotoxicity Multiorgan failure Therapeutic plasma exchange Continuous renal replacement therapy Case report