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plasma Cell Neoplasms, Clinicopathological Characteristics and Immunophenotype of 21 patients

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Open Journal of pathology 2012年第4期2卷 127-132页

作者： Mónica belinda Romero-Guadarrama Cinthia Adriana Meza Medina Elvira Aguilar Martínez Facultad de Medicina Universidad Autónoma de Nayarit Tepic Mexico Unidad de Hematología del Hospital General de México Mexico City Mexico Unidad de patología del Hospital General de México Mexico City Mexico

Introduction: plasma cell neoplasms are monoclonal proliferations characterized by the secretion of an immunoglobulin product known as component "M" or monoclonal. The World Health Organization (WHO 2008) defines as plasma cell neoplasms the following: plasma cell myeloma, plasmacytoma and those syndromes defined by immunoglobulin deposits and primary amyloidosis, The objective of the present work was to correlate their clinical, morphological and phenotype characteristics in 21 patients. Material and Methods: A 2-year retrospective review was performed of the files of the surgical pathology laboratory and of the hematology service of the General Hospital of Mexico, searching for patients with a diagnosis of plasma cell neoplasm. We analyzed the following variables: age, gender, clinical symptoms, evolution, localization, laboratory tests, morphology, and expression of immunohistochemical markers. Of the 21 patients, 12 (57.1%) corresponded to plasma cell myelomas and 9 (42.8%) were plasmacytomas (seven extraosseous and two solitary bone plasmacytoma);women predominated with 61.4% and age ranged between 22 and 84 years. Mass and epistaxis were observed in the patients with plasmacytomas, and symptoms of medullary compression and anemia were observed in those patients with plasma cell myeloma. The time of symptomatology varied from 3 to 12 months. Laboratory tests revealed that lactate dehydrogenase (LDH), beta 2 microglobulin, C-reactive protein were altered and that hypercalcemia and anemia were present more in the systemic form of the disease. Treatment depended on the clinical staging and laboratory data. Mature forms predominated morphologically. Immunohistochemical stain revealed a constant expression for CD 138, six patients expressed CD 56, and expression of the Kappa and Lambda light chains was while.

关键词： plasma Cell Neoplasms

不同污泥龄对活性污泥系统处理各种药物的影响

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中国给水排水 2012年第13期28卷 99-102,108页

作者：杨程郭劲松 belinda s.M.sturm Rachael F.Lane Craig D.Adams Ray E.Carter 重庆大学城市建设与环境工程学院重庆400045 美国堪萨斯大学土木建筑与环境工程学院

运行4个实验室规模(3 L)的序批式活性污泥反应器(sBR),其污泥龄(sRT)分别为2、8、14、20 d。批次摇瓶试验通过设置3个工况(正常运行、加入生物抑制剂、无微生物)来讨论5种污泥(4个sBR和当地污水处理厂)对浓度为5μg/L的10种药物的处理效... 详细信息

运行4个实验室规模(3 L)的序批式活性污泥反应器(sBR),其污泥龄(sRT)分别为2、8、14、20 d。批次摇瓶试验通过设置3个工况(正常运行、加入生物抑制剂、无微生物)来讨论5种污泥(4个sBR和当地污水处理厂)对浓度为5μg/L的10种药物的处理效果,以及在一个运行周期(8 h)中吸附作用、生物降解作用和挥发损失的去除贡献。试验结果显示,对乙酰氨基酚、咖啡因基本能被去除,去除率在60%以上,立痛定、磺胺甲恶唑能被部分去除,去除率为30%～55%;降固醇酸、林肯霉素、甲氧苄啶的处理效果不好,去除率p<0.02)。

关键词：活性污泥系统磺胺类抗生素污泥龄药物

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选秀奇葩:一夜成名的背后

高中生（作文） 2012年第11期 40-41页

作者： belinda Luscombe Ernest

除了那些提不起精神和毫无耐心的人，对我们所有人而言，苏珊·波伊尔和保罗·帕兹的故事都是令人无限神往的。似乎是经过电视选秀节目《英国达人》的发掘，人们猛然发现，这两位工人阶级出身、地位低微、长相平平的人竞能唱出美妙的歌... 详细信息

除了那些提不起精神和毫无耐心的人，对我们所有人而言，苏珊·波伊尔和保罗·帕兹的故事都是令人无限神往的。似乎是经过电视选秀节目《英国达人》的发掘，人们猛然发现，这两位工人阶级出身、地位低微、长相平平的人竞能唱出美妙的歌曲，令人刮目相看。

关键词：中学英语课外阅读阅读材料

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高管薪酬治理来自全球的最佳实践

中外管理 2007年第7期 76-78页

作者： Diane Doubleday belinda Hudson piia pilv paul Riggs Lisa slipp 美世咨询

中国企业高管越来越复杂的薪酬体制和越来越高的酬劳数字，都让高管薪酬治理成为口渐受到关注的管理话题。看看全球最佳实践的建议吧。

关键词：高管薪酬实践治理薪酬体制中国企业管理

Knowledge and skills in Advanced swimming and Life-saving Techniques: A Correlational study

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Journal of shipping and Ocean Engineering 2022年第1期12卷 27-32页

作者： Roderick R.Germo Brian Gil s.sarinas Emilie C.Coo Marlon R.Terunez belinda E.Gavadan Cherry Y. Bachelor of science in Marine Transportation(BsMT)Department John B.Lacson Foundation Maritime University(Arevalo)Inc.Sto.Nino SurArevaloIloilo City 5000Philippines

This descriptive-correlational study was conducted to determine the relationship between the knowledge and skills of the BsMT (Bachelor of science in Maritime Transportation) students in pE (physical Education) 2 (Advanced swimming and Life-saving Techniques). The respondents of the study were the 40 second year BsMT students that were taken through purposive sampling. The study utilized a researcher-made questionnaire for both knowledge and skills that had undergone validity and reliability-testing. Descriptive and inferential statistics were used to analyze the data such as mean, standard deviation, and spearman’s rho. Results revealed that their knowledge on Advanced swimming and Life-saving Techniques was “Fair” while the skills of the second year BsMT students were “Very good”. Furthermore, the knowledge of the BsMT students had a positive correlation (substantial) with their skills on Advanced swimming and Life-saving Techniques. The second year BsMT students are encouraged to undergo trainings and upgrading to enhance their knowledge and skills in Advanced swimming and Life-saving Techniques in order for them to become life-long learners.

关键词： Maritime education advanced swimming life-saving techniques descriptive-correlational

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黄脊竹蝗在中国的发生及防控技术

中国生物防治学报 2022年第2期38卷 531-536页

作者：李红梅王珺雅卓富彦朱景全涂雄兵张国财 belinda Luke 中国农业科学院植物保护研究所/农业农村部-CABI生物安全联合实验室北京100193 CABI东亚中心北京100081 东北林业大学哈尔滨150040 全国农业技术推广服务中心北京100125 CABI英国埃格姆 TW209TY

黄脊竹蝗为重大林业害虫,多在竹林造成为害。2020年黄脊竹蝗从老挝、越南等地跨境进入中国云南省并在农区造成了严重为害。本文主要综述了黄脊竹蝗在我国发生的历史与现状、暴发的原因以及主要的防治措施,归纳了黄脊竹蝗不同发育阶段的... 详细信息

黄脊竹蝗为重大林业害虫,多在竹林造成为害。2020年黄脊竹蝗从老挝、越南等地跨境进入中国云南省并在农区造成了严重为害。本文主要综述了黄脊竹蝗在我国发生的历史与现状、暴发的原因以及主要的防治措施,归纳了黄脊竹蝗不同发育阶段的有效防治措施,重点总结了利用生防天敌和生物农药防治黄脊竹蝗的研究进展,为黄脊竹蝗综合防控提供参考依据。

关键词：黄脊竹蝗跨境生物防治天敌生物农药

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建网站、开博客——欧美业主卖房有新招

住宅与房地产（中） 2006年第12期 19-20页

作者： belinda Archer 张征（译）

艾弗·雅各布斯（Ivor Jacobs）决定卖掉位于英国德比郡价值600万英镑的Hopwell Hall豪宅时，建立了自己的专属网站帮助推销。

关键词：网站卖房业主欧美博客英镑豪宅推销

Gemcitabine and cisplatin treatment over a 3-week versus a 4-week dosing schedule： a randomized trial coducted in Chinese patients with nonsmall cell lung cancer

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Chinese Medical Journal 2008年第10期121卷 892-897页

作者： LIAO Mei-lin ZHU Yun-zhong LI Long-yun WAN Huan-ying YU shi-ying belinda HALL Teena WEsT WANG Li Clinical Medical Centre of Lung Tumour Shanghai ChestHospital Shanghai 200030 China Department of Oncology Beijing Chest Tumour Hospital Beijing 101149 China Department of pulmonary Medicine Peking Union HospitalBeijing 100730 China Department of pulmonary Medicine Shanghai Ruijin HospitalShanghai 20025 China Center of Oncology Tongji Hospital Wuhan 430030 China Intercontinental Information sciences Eli Lilly Australia PtyLimited Australia Eli Lilly Asia Shanghai Office Shanghai 200021 China

Background Gemcitabine plus cisplatin is a standard treatment for stages IIIB and IV nonsmall cell lung cancer （NsCLC）. This randomized phase Ⅱ study evaluated a 3-week versus a 4-week schedule of gemcitabine-cisplatin as first line treatment for Chinese patients with advanced NsCLC. Methods patients were randomized to receive cisplatin 75 mg/m^2 on day 1 plus either gemcitabine 1250 mg/m^2 on days 1 and 8 of a 21-day cycle （3-week group） or gemcitabine 1000 mg/m2 on days 1,8 and 15 of a 28-day cycle （4-week group）. Results One hundred patients were enrolled in this study. The response rate was 24% （12/51 patients） in the 3-week group and 27% （13/49 patients） in the 4-week group. There were no statistically significant differences between the two treatment groups in survival （hazard ratio： 1.19; 95% CI： 0.68-2.09） with a median survival of 12.1 months and 13.8 months in the 3-week group and the 4-week group respectively. The rate of grade 3/4 toxicity in the 3-week group was 55% compared with 86% in the 4-week group （p=0.001）. The difference in the incidence of grade 3/4 haematological toxicities did not reach statistical significance （3-week： 37%, 4-week： 57%）, however grade 3/4 drug related neutropenia （3-week： 27%, 4-week： 51%） and thrombocytopenia （3-week： 8%, 4-week： 31%） were significantly lower in the 3-week group. Grade 3/4 nonhaematological toxicities were less in the 3-week group （33% cf 63%; p=0.005）. Conclusions The differences in the efficacy endpoints were all in favour of the 4-week schedule of gemcitabine plus cisplatin, however these differences did not reach statistical significance. Fewer grade 3/4 toxicities were observed in the 3-week group compared with the 4-week group.

关键词： chemotherapy gemcitabine cisplatin carcinoma, nonsmall cell lung

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选秀奇葩：一夜成名的背后

英语学习 2012年第6期 10-12页

作者： belinda Luscombe 丁玎（选注）

人们总喜欢听这样的故事，相貌平常的家伙却身怀绝技，当时间终于来临，青蛙变成王子，灰姑娘变成白雪公主。

关键词：选秀白雪公主灰姑娘