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Biological Control of Soilborne Pathogens （Fusarium oxysporum F, Sp. Cucumerinum） of Cucumber （Cucumis sativus） by Trichoderma sp,

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Journal of Life Sciences 2018年第1期12卷 1-12页

作者： Estifanos Tsegaye Redda Jing Ma Jie Mei Mei Li beilei wu Xiliang Jiang Chinese Academy of Agricultural Sciences Institutes of Plant Protection Beijing 100193 P. R. China

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中国家庭孩子教育成本及其影响因素研究

人口学刊 2023年第6期45卷 16-35页

作者：杨凡吴蓓蕾中国人民大学人口与发展研究中心北京100872

当前我国已处于深度低生育水平时期,家庭规模缩减、少子化特征愈发突出。同时,生育政策进一步调整优化,优生优育的观念获得普遍认同,在较高的教育期望驱使下,越来越多的家庭开始在孩子的教育方面花费更多的时间和金钱。本文基于2019年... 详细信息

当前我国已处于深度低生育水平时期,家庭规模缩减、少子化特征愈发突出。同时,生育政策进一步调整优化,优生优育的观念获得普遍认同,在较高的教育期望驱使下,越来越多的家庭开始在孩子的教育方面花费更多的时间和金钱。本文基于2019年全国人口与家庭动态监测调查数据,利用多层线性模型、似不相关回归等分析方法,研究低生育率背景下中国家庭孩子的教育成本投入状况及其影响因素。研究发现:宏观层次的地区经济、教育发展差异和微观层次的家庭社会经济资源都是影响教育成本差异的原因。地区之间家庭教育成本差异大多源自家庭及个体层次特征构成的不同,仅有地区平均受教育年限具有独立影响。宏观因素还会对微观因素的影响产生调节作用,使稀释效应、家庭资源优势等各种效应更加凸显。资源稀释效应在低生育率背景下仍然成立,但出现了女孩的教育经济成本投入超过男孩的现象。经济成本和时间成本的影响因素存在共性和差异。在家庭内部分工方面,母亲承担了更多的陪伴和教育子女的责任,父亲的时间成本投入有明显的城乡差异。为了改善家庭面临的教育成本问题,应针对不同地区、不同阶段家庭教育成本的差异化特点,制定更具针对性的家庭支持政策;应倡导父母双方共同参与孩子的养育和教育过程,缓解母亲的养育教育压力;应推进落实双减政策,完善教育资源配置和教育服务优化,多举措促进教育资源的均等化。

关键词：家庭教育成本资源稀释性别差异低生育率

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体育锻炼对中国老年人抑郁程度的影响研究

中国体育科技 2023年第1期59卷 38-43页

作者：杨凡吴蓓蕾王富百慧中国人民大学人口与发展研究中心北京100872 国家体育总局体育科学研究所北京100061

基于2016年中国老年社会追踪调查数据,运用多元线性回归和结构方程模型对体育锻炼影响老年人抑郁程度及其机制进行探究。研究表明,社会人口学特征、身体健康和社会支持因素都对老年人的抑郁得分有显著影响;在控制其他变量后,体育锻炼对... 详细信息

基于2016年中国老年社会追踪调查数据,运用多元线性回归和结构方程模型对体育锻炼影响老年人抑郁程度及其机制进行探究。研究表明,社会人口学特征、身体健康和社会支持因素都对老年人的抑郁得分有显著影响;在控制其他变量后,体育锻炼对降低老年人的抑郁得分仍具有显著作用。体育锻炼对城乡老年人抑郁状况的影响存在异质性,体育锻炼减少抑郁的作用在城市老年人中更为显著。体育锻炼在直接降低老年人抑郁得分的同时,也通过提升老年人的身体健康水平和同伴支持程度间接降低了其抑郁发生的可能性。

关键词：体育锻炼老年人抑郁程度心理健康身体健康社会支持

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山楂茶复合果酒酿造工艺研究

食品工程 2022年第4期 41-43页

作者：吴蓓蕾山西彤康食品有限公司山西晋城048004

通过将山楂叶与纯水按照1∶50的比例进行浸提后过滤得到茶水,用茶水代替纯水与山楂果按照1.5∶1的比例混合预煮打浆后共同发酵,采用EC1118酿酒酵母为发酵剂进行发酵。用该方法生产出的山楂茶复合果酒色泽清亮饱满,茶香与果香怡人,口感... 详细信息

通过将山楂叶与纯水按照1∶50的比例进行浸提后过滤得到茶水,用茶水代替纯水与山楂果按照1.5∶1的比例混合预煮打浆后共同发酵,采用EC1118酿酒酵母为发酵剂进行发酵。用该方法生产出的山楂茶复合果酒色泽清亮饱满,茶香与果香怡人,口感醇厚协调。

关键词：山楂茶复合果酒

Cobalt doping amount determines dominant reactive species in peroxymonosulfate activation via porous carbon catalysts co-doped by cobalt and nitrogen

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Journal of Environmental Sciences 2024年第4期138卷 212-226页

作者： Xiang Li Limeng wu Aiqin Zhang Shaohua wu Yan Lin Chunping Yang Key Laboratory of Jiangxi Province for Persistent Pollutants Control and Resources Recycle Nanchang Hangkong UniversityNanchang 330063China Academy of Environmental and Resource Sciences School of Environmental Science and EngineeringGuangdong University of Petrochemical TechnologyMaoming 525000China College of Environmental Science and Engineering Hunan University and Key Laboratory of Environmental Biology and Pollution Control(Hunan University)Ministry of EducationChangsha 410082China

Switching the reaction routes in peroxymonosulfate(PMS)-based advanced oxidation processes have attracted much attention but remain challenging.Herein,a series of Co-N/C catalysts with different compositions and structures were prepared by using bimetallic zeolitic imidazolate frameworks based on ZIF-8 and ZIF-67(x Zn/Co-ZIFs).Results show that Co doping amount could mediate the transformation of the activation pathway of PMS over CoN/C.When Co doping amount was less than 10%,the constructed x Co-N/C/PMS system(x≤10%)was singlet oxygen-dominated reaction;however further increasing Co doping amount would lead to the generation and coexistence of sulfate radicals and high-valent cobalt,besides singlet oxygen.Furthermore,the nitrogen-coordinated Co(Co-NX)sites could serve as main catalytically active sites to generate singlet oxygen.While excess Co doping amount caused the formation of Co nanoparticles from which leached Co ions were responsible for the generation of sulfate radicals and high-valent cobalt.Compared to undoped N/C,Co doping could significantly enhance the catalytic performance.The 0.5%Co-N/C could achieve the optimum degradation(0.488 min^(-1))and mineralization abilities(78.4%)of sulfamethoxazole among the investigated Co-N/C catalysts,which was superior to most of previously reported catalysts.In addition,the application prospects of the two systems in different environmental scenarios(pH,inorganic anions and natural organic matter)were assessed and showed different degradation behaviors.This study provides a strategy to regulate the reactive species in PMS-based advanced oxidation process.

关键词： Peroxymonosulfate Sulfate radical Singlet oxygen Cobalt Zeolitic imidazolate framework Advanced oxidation process

The physiological role of the unfolded protein response in the nervous system

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Neural Regeneration Research 2024年第11期19卷 2411-2420页

作者： Shuangchan wu Wensheng Lin Department of Neuroscience University of MinnesotaMinneapolisMNUSA Institute for Translational Neuroscience University of MinnesotaMinneapolisMNUSA

The unfolded protein response(UPR)is a cellular stress response pathway activated when the endoplasmic reticulum,a crucial organelle for protein folding and modification,encounters an accumulation of unfolded or misfolded proteins.The UPR aims to restore endoplasmic reticulum homeostasis by enhancing protein folding capacity,reducing protein biosynthesis,and promoting protein degradation.It also plays a pivotal role in coordinating signaling cascades to determine cell fate and function in response to endoplasmic reticulum stress.Recent research has highlighted the significance of the UPR not only in maintaining endoplasmic reticulum homeostasis but also in influencing various physiological processes in the nervous system.Here,we provide an overview of recent findings that underscore the UPR’s involvement in preserving the function and viability of neuronal and myelinating cells under physiological conditions,and highlight the critical role of the UPR in brain development,memory storage,retinal cone development,myelination,and maintenance of myelin thickness.

关键词： myelin neuron oligodendrocyte Schwann cell unfolded protein response

LONP1 ameliorates liver injury and improves gluconeogenesis dysfunction in acute-on-chronic liver failure

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Chinese Medical Journal 2024年第2期137卷 190-199页

作者： Muchen wu Jing wu Kai Liu Minjie Jiang Fang Xie Xuehong Yin Jushan wu Qinghua Meng Department of Liver Disease Beijing You-An HospitalCapital Medical UniversityBeijing 100069China Beijing Institute of Hepatology Beijing You-An HospitalCapital Medical UniversityBeijing 100069China Department of General Surgery Beijing You-An HospitalCapital Medical UniversityBeijing 100069China

Background:Acute-on-chronic liver failure(ACLF)is a severe liver disease with complex pathogenesis.Clinical hypoglycemia is common in patients with ACLF and often predicts a worse prognosis.Accumulating evidence suggests that glucose metabolic disturbance,especially gluconeogenesis dysfunction,plays a critical role in the disease progression of ACLF.Lon protease-1(LONP1)is a novel mediator of energy and glucose metabolism.However,whether gluconeogenesis is a potential mechanism through which LONP1 modulates ACLF remains unknown.Methods:In this study,we collected liver tissues from ACLF patients,established an ACLF mouse model with carbon tetrachloride(CCl 4),lipopolysaccharide(LPS),and D-galactose(D-gal),and constructed an in vitro hypoxia and hyperammonemia-triggered hepatocyte injury model.LONP1 overexpression and knockdown adenovirus were used to assess the protective effect of LONP1 on liver injury and gluconeogenesis regulation.Liver histopathology,biochemical index,mitochondrial morphology,cell viability and apoptosis,and the expression and activity of key gluconeogenic enzymes were detected to explore the underlying protective mechanisms of LONP1 in ACLF.Results:We found that LONP1 and the expressions of gluconeogenic enzymes were downregulated in clinical ACLF liver tissues.Furthermore,LONP1 overexpression remarkably attenuated liver injury,which was characterized by improved liver histopathological lesions and decreased serum alanine aminotransferase(ALT)and aspartate aminotransferase(AST)in ACLF mice.Moreover,mitochondrial morphology was improved upon overexpression of LONP1.Meanwhile,the expression and activity of the key gluconeogenic enzymes were restored by LONP1 overexpression.Similarly,the hepatoprotective effect was also observed in the hepatocyte injury model,as evidenced by improved cell viability,reduced cell apoptosis,and improved gluconeogenesis level and activity,while LONP1 knockdown worsened liver injury and gluconeogenesis disorders.Conclusion:We demonstrated that gluconeogenesis dysfunc

关键词： Acute-on-chronic liver failure Lon protease-1 Gluconeogenesis disturbance Mitochondrial dysfunction Metabolism

Ballistic performances of the hourglass lattice sandwich structures under high-velocity fragments

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Defence Technology（防务技术） 2024年第1期31卷 312-325页

作者： He-xiang wu Jia Qu Lin-zhi wu Key Laboratory of Advanced Ship Materials and Mechanics College of Aerospace and Civil EngineeringHarbin Engineering UniversityHarbin150001China School of Civil Engineering Northeast Forestry UniversityHarbin150040China

In this paper,the numerical simulation method is used to study the ballistic performances of hourglass lattice sandwich structures with the same mass under the vertical incidence of fragments.Attention is paid to elucidating the influences of rod cross-section dimensions,structure height,structure layer,and rod inclination angle on the deformation mode,ballistic performances,and ability to change the ballistic direction of fragments.The results show that the ballistic performances of hourglass lattice sandwich structures are mainly affected by their structural parameters.In this respect,structural parameters optimization of the hourglass lattice sandwich structures enable one to effectively improve their ballistic limit velocity and,consequently,ballistic performances.

关键词： Hourglass lattice sandwich structures Ballistic performances high-velocity Finite element analysis

Resilience-incorporated seismic risk assessment of precast concrete frames with“dry”connections

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Earthquake Engineering and Engineering Vibration 2024年第2期23卷 403-425页

作者： wu Chenhao Tang Yuchuan Cao Xuyang wu Gang Key Laboratory of Concrete and Prestressed Concrete Structures of the Ministry of Education Nanjing 211102China Department of Civil and Environmental Engineering University of CaliforniaLos AngelesCA 90095USA School of Civil Engineering Southeast UniversityNanjing 211102China College of Civil and Transportation Engineering Hohai UniversityNanjing 210024China

A resilience-incorporated risk assessment framework is proposed and demonstrated in this study to manifest the advantageous seismic resilience of precast concrete frame(PCF)structures with“dry”connections in terms of their low damage and rapid recovery.The framework integrates various uncertainties in the seismic hazard,fragility,capacity,demand,loss functions,and post-earthquake recovery.In this study,the PCF structures are distinguished from ordinary reinforced concrete frame(RCF)structures by characterizing multiple limit states for the PCF based on its unique damage mechanisms.Accordingly,probabilistic story-wise pushover analyses are performed to yield story-wise capacities for the predefined limit states.In the seismic resilience analysis,a step-wise recovery model is proposed to idealize the functionality recovery process,with separate considerations of the repair and non-repair events.The recovery model leverages the economic loss and downtime to delineate the stochastic post-earthquake recovery curves for the resilience loss estimation.As such,contingencies in the probabilistic post-earthquake repairs are incorporated and the empirical judgments on the recovery parameters are largely circumvented.The proposed framework is demonstrated through a comparative study between two“dry”connected PCFs and one RCF designed as alternative structural systems for a prototype building.The results from the risk quantification indicate that the PCFs show reduced loss hazards and lower expected losses relative to the RCF.Particularly,the PCF equipped with energy dissipation devices at the“dry”connections largely reduces the expected economic loss,downtime,and resilience loss by 29%,56%,and 60%,respectively,compared to the RCF.

关键词： precast concrete frame non-emulative precast system seismic resilience seismic risk functional recovery