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2010 Chinese Control and Decision Conference

作者： Bingru Yang~1,Wu Qu~1,Yun Zhai~(1,2),Haifeng Sui~1 1.School of Information Engineering,University of science and Technology beijing,beijing 100083 2.college of computer science,Liaocheng University Liaocheng,252059,China

＜正＞Methods for predicting protein secondary structure provide information that is useful both in ab initio structure prediction and as additional restraints for fold recognition *** structure predictions may also be used to guide the design of site directed mutagenesis studies,and to locate potential functionally important *** this article,we propose a method of improved SVM for predicting protein secondary *** evolutionary information contained in amino acid’s physicochemical properties, position-specific scoring matrix generated by psi-blast as input to improved SVM,secondary structure can be predicted at significantly increased *** on KDTICM theory,we have constructed a compound pyramid model,which is composed of four layers of the intelligent interface and integrated in several ways, such as improved SVM,mixed-modal BP,KDD* method and so *** the RS126 data set,state overall per-residue accuracy,Q3 reached 83.06%,while SOV99 accuracy increased to 80.6%.On the CB513 data set, Q3 reached 80.49%,SOV99 accuracy increased to 79.84%.This article briefly introduces this model and highlights the improved SVM method.

关键词： Protein Second Structure SVM Compound Pyramid Model

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基于数据仓库的EIS数据管理体系结构

计算机工程与应用 2003年第19期39卷 17-20页

作者：王锁柱孙玉芳中国科学院软件研究所山西师范大学数学与计算机学院临汾041004

该文采用数据仓库的思想构建了EIS的数据管理体系结构,以满足EIS的数据分布性、格式多样性和结构复杂性的要求,克服了现有EIS响应速度低、可用性差等方面的缺陷。在该体系结构中,分别设置了硬信息获取、软信息挖掘模块和硬软信息集成、... 详细信息

该文采用数据仓库的思想构建了EIS的数据管理体系结构,以满足EIS的数据分布性、格式多样性和结构复杂性的要求,克服了现有EIS响应速度低、可用性差等方面的缺陷。在该体系结构中,分别设置了硬信息获取、软信息挖掘模块和硬软信息集成、链接模块,并就实现的关键技术提出了解决方式。

关键词：高层管理信息系统数据管理数据仓库

Theory and techniques of data mining in CGF behavior modeling

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science China(Information sciences) 2011年第4期54卷 717-731页

作者： YIN YunFei 1,2,GONG GuangHong 2 & HAN Liang 2 1 college of computer science,Chongqing University,Chongqing 400044,China 2 School of Automation science and Electrical Engineering,beijing University of Aeronautics and Astronautics,beijing 100083,China college of computer science Chongqing University Chongqing China School of Automation science and Electrical Engineering Beijing University of Aeronautics and Astronautics Beijing China

For the large quantity of data,rules and models generated in the course of computer generated forces (CGFs) behavior modeling,the common analytical methods are statistical methods based on the tactical rules,tactical doctrine and empirical ***,from the viewpoint of data mining,we can find many of these analytical methods are also each-and-every different data mining *** this paper,we survey the data mining theory and techniques that have appeared in the course of CGF behavior modeling from the viewpoint of data ***,we redefine and reclassify these theories and techniques according to the research requirements of data mining (the knowledge structure of data mining).We aim to help the CGF investigators to learn the key points and the research methods of the data intelligent processing in the CGF behavior modeling,and thus we can provide the references for the colleagues who are engaged in the research and practice of the CGF behavior modeling by this *** also introduce our ongoing work on the CGF behavior modeling based on data mining.

关键词： CGF CGF behavior modeling data mining theory and techniques

The structural analysis of fuzzy measures

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science China(Information sciences) 2011年第1期54卷 38-50页

作者： ZHANG Ling1,ZHANG Bo2 & ZHANG YanPing1 1 computer science college,Anhui University,Hefei 230039,China 2State Key Lab of Intelligent Technology & Systems Tsinghua National Lab for Information science & Technology Information science & Technology college,computer science & Technology,Tsinghua University,beijing 100084,China computer science college Anhui University Hefei China State Key Lab of Intelligent Technology & Systems Tsinghua National Lab for Information science & Technology Information science & Technology college Computer Science & Technology Tsinghua University Beijing China

From quotient space based granular computing theory we explore the fuzzy measures of fuzzy sets. Based on the structural analysis of fuzzy sets,we present an"isotropism"*** this assumption we achieved the following insights:(1)the uniqueness of a fuzzy measure being isotropic on a finite complete semi-ordered set;(2)the necessary and suffcient condition of the isomorphism for fuzzy measure functions in fuzzy mathematics;(3)the necessary and suffcient condition that fuzzy measures have fuzzy and granular monotonicity;(4)under a certain assumption,the analytic expression for fuzzy *** results clarify the relationship between fuzzy measures and granular computing,reveal the essence of fuzzy measures,and provide a simple way of constructing fuzzy measures.

关键词： quotient space fuzzy set fuzzy measure rough set structural analysis

Cu(Ⅱ) Potentiation of Alzheimer Aβ1-40 Cytotoxicity and Transition on its Secondary Structure

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Acta Biochimica et Biophysica Sinica 2006年第11期38卷 765-772页

作者： Xue-Ling DAI~1 Ya-Xuan SUN~2 Zhao-Feng JIANG~2* 1 college of Life science,Capital Normal University,beijing 100037,China 2 college of Applied sciences and Humanities,beijing Union University,beijing 100083,China college of Life science Capital Normal UniversityBeijing 100037 China college of Applied sciences and Humanities Beijing Union UniversityBeijing 100083 China

Mounting evidence has shown that dyshomeostasis of the redox-active biometals such as Cuand Fe can lead to oxidative stress,which plays a key role in the neuropathology of Alzheimer's disease（AD）.Here we demonstrate that with the formation of Cu（Ⅱ）·Aβ1-40 complexes,copper markedly potentiatesthe neurotoxicity exhibited by β-amyloid peptide （Aβ）.A greater amount of hydrogen peroxide was releasedwhen Cu（Ⅱ）·Aβ1-40 complexes was added to the xanthine oxidase/xanthine system detected by potassiumiodide *** bound to Aβ1-40 was observed by electron paramagnetic resonance（EPR） *** dichroism （CD） studies indicated that copper chelation could cause a structuraltransition of Aβ.The addition of copper to Aβ introduced an increase on β-sheet as well as α-helix,whichmay be responsible for the aggregation of Aβ.We hypothesized that Aβ aggregation induced by copper maybe responsible for local injury in *** interaction between Cu2+and Aβ also provides a possible mechanismfor the enrichment of metal ions in amyloid plaques in the AD brain.

关键词： Alzheimer’s disease Cu(Ⅱ)·Aβ1-40 complex neuron injury Aβ secondary structure

Theoretical analysis of alloy multiplying factor by the empirical electron theory of solids and molecules

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science China(Technological sciences) 2007年第6期50卷 807-814页

作者： SONG YuePeng1,2, LIU GuoQuan2, LI ZhiLin3, FENG ChengMing1 1 Mechanical and Electronic Engineering college, Shandong Agricultural University, Tai’an 271018, China 2 college of Materials science and Engineering, University of science and Technology, beijing 100083, China 3 college of Material science and Engineering, beijing University of Chemical Technology, beijing 100029, China Mechanical and Electronic Engineering college Shandong Agricultural University Tai’an China college of Materials science and Engineering University of Science and Technology Beijing China college of Material science and Engineering Beijing University of Chemical Technology Beijing China

By introducing the distribution probability of structural units in austenite contain- ing alloying elements and considering its effects on phase transformation, this paper establishes a calculation model of distribution probability of structural units. A new valence electron structure (VES) parameter-transformation effect coefficient of alloying elements (HL), is defined and then studied both theoretically and ex- perimentally. The relationship between the parameter HL and the multiplying factor (the quenching capability factor) of alloying elements is studied. The results indi- cate that the two parameters (HL and the quenching capability factor) have the same variation characteristic and substance feature. Therefore, the multiplying factor virtually expresses the relative quantity of structural units in the alloying elements-containing austenite.

关键词： multiplying factor (the quenching capability factor), empirical electron theory of solids and molecules, transformation effect coefficient of alloying elements, structural units in austenite containing alloying elements

Threshold quantum secure direct communication without entanglement

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science China(Physics,Mechanics & Astronomy) 2008年第2期51卷 176-183页

作者： YANG YuGuang1,3 & WEN QiaoYan2 1 college of computer science and Technology, beijing University of Technology, beijing 100022, China 2 School of science, beijing University of Posts and Telecommunications, beijing 100876, China 3 State Key Laboratory of Information Security (Graduate School of Chinese Academy of sciences), beijing 100049, China college of computer science and Technology Beijing University of Technology Beijing China State Key Laboratory of Information Security (Graduate School of Chinese Academy of sciences) Beijing China School of science Beijing University of Posts and Telecommunications Beijing China

For the first time, a threshold quantum secure direct communication (TQSDC) scheme is presented. Similar to the classical Shamir's secret sharing scheme, the sender makes n shares, S1, …, Sn of secret key K and each receiver keeps a share secretly. If the sender wants to send a secret message M to the receivers, he en-codes the information of K and M on a single photon sequence and sends it to one of the receivers. According to the secret shares, the t receivers sequentially per-form the corresponding unitary operations on the single photon sequence and ob-tain the secret message M. The shared shares may be reusable if it can be judged that there is no eavesdropper in line. We discuss that our protocol is feasible with current technology.

关键词： quantum secure direct communication threshold secure direct communication quantum secret sharing

Analysis of a kind of quantum cryptographic schemes based on secret sharing

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science China(Physics,Mechanics & Astronomy) 2009年第9期52卷 1313-1316页

作者： ZHANG XingLan1 & JI DongYao2 1 college of computer science and Technology, beijing University of Technology, beijing 100124, China 2 State Key Laboratory of Information Security, Graduate University of Chinese Academy of sciences, beijing 100049, China college of computer science and Technology Beijing University of Technology Beijing China State Key Laboratory of Information Security Graduate University of Chinese Academy of Sciences Beijing China

Recently, Yang et al. proposed a kind of quantum cryptographic schemes based on secret sharing. The main idea is drawn from the case, where any n participants who share a secret K can co-operate as K does. This process can be applied to encryption, authentication, signature and so on. Unfortunately, since there is no identity authentication of the share's holder, these schemes inherit the limitation of secret sharing in practice. If some participants do not follow the protocol, the protocol would be a failure at last. Moreover, these schemes encounter another serious attack. Any two participants can co-operate to defeat the schemes by sending different shares to the parties unknown to the distributor of the secret K, such that these parties can execute the protocol as well. The attack proves that it is not enough for quantum cryptographic schemes that only the secret key is secure.

关键词： quantum identity authentication quantum secure direct communication quantum signature secret sharing

Protective Effects of Vitamin E against Oxidative Damage Induced by Aβ(1-40)Cu(Ⅱ)Complexes

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Acta Biochimica et Biophysica Sinica 2007年第2期39卷 123-130页

作者： Xueling DAI~1 Yaxuan SUN~2 and Zhaofeng JIANG~2 ~1college of Life science,Capital Normal University,Bejing 100037,China ~2college of Applied sciences Humanities of beijing Union University,beijing 100083,China college of Life science Capital Normal UniversityBeijing 100037 China college of Applied sciences and Humanities of beijing Union Universitybeijing 100083 China

β-amyloid peptide （Aβ） is considered to be responsible for the formation of senile plaques,which is the hallmark of Alzheimer's disease （AD）.Oxidative stress,manifested by protein oxidation andlipid peroxidation,among other alterations,is a characteristic of AD brain.A growing body of evidence hasbeen presented in support of Aβ1-40forming an oligomeric complex that binds copper at a CuZn superoxidedismutase-like binding site. Aβ1-40Cu（Ⅱ） complexes generate neurotoxic hydrogen peroxide （H2O2） from O2via Cue+ reduction,though the precise reaction mechanism is *** toxicity of Aβ1-40or the Aβ1-40Cu（Ⅱ）complexes to cultured primary cortical neurons was partially attenuated when （+）-α-tocopherol （vitamin E）as free radical antioxidant was added at a concentration of 100 μ*** data derived from lactate dehydro-genase （LDH） release and the formation of H2O2confirmed the results from the MTT *** findingsindicate that copper binding to Aβ1-40can give rise to greater production of H2O2, which leads to a break-down in the integrity of the plasma membrane and subsequent neuronal *** treated with vitaminE exhibited much slighter damage,suggesting that vitamin E plays a key role in protecting neuronal cellsfrom dysfunction or death.

关键词： Aβ1-40Cu(II)complex vitamin E neuronal oxidative damage H2O2 generation lactate dehydrogenase(LDH)release