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[Det.rminat.on of eight.pht.alate met.bolit.s in urine of pregnant.women and evaluat.on of neonat.l birt. out.omes based on solid-phase ext.act.on-high performance liquid chromat.graphy-t.ndem mass spect.omet.y]

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Se pu = Chinese journal of chromat.graphy 2025年第1期43卷 60-67页

作者： Zi-Hao Wang Meng-Fei Xu bei-Ni Li Ping Wu Wei Wu Hubei Universit. of Chinese Medicine Wuhan 430065 China.

Pht.alates (PAEs) are endocrine-disrupt.ng chemicals t.at.are widely present.in everyday life and ent.r t.e human body t.rough various pat.ways. t.e release of PAEs int. t.e environment.t.rough pat.ways t.at.include leaching, evaporat.on, abrasion, and t.e use of personal care product. exposes humans t. PAEs via ingest.on, inhalation, and dermal absorpt.on. Pregnant.women, as a part.cularly vulnerable population, risk adverse newborn growt. and development.when exposed t. PAEs. While t.e concent.at.ons of PAEs in urine reflect.recent.exposure levels in humans, urinary levels of pht.alate met.bolit.s (mPAEs) are commonly used as biomarkers of int.rnal exposure owing t. t.e relatively short.biological half-lives of PAEs (t.is st.dy, we developed a solid-phase ext.act.on-high performance liquid chromat.graphy-t.ndem mass spect.omet.y (SPE-HPLC-MS/MS) met.od for simult.neously det.ct.ng eight.mPAEs in t.e urine of pregnant.women. Urine samples were enzymat.cally hydrolyzed wit. -glucosidase and t.en purified using t.e Bond Elut.Plexa SPE column, wit. subsequent.elut.on, concent.at.on, and redissolved performed prior t. HPLC-MS/MS. Separat.on was achieved using an Agilent.Eclipse Plus C18 column (100 mm×3 mm, 3.5 μm), wit. gradient.elut.on performed using 0.1% acet.c acid aqueous solut.on and 0.1% acet.c acid acet.nit.ile as mobile phases. Mult.ple react.on monit.ring (MRM) mode was used for det.ct.on, wit. quant.ficat.on performed using t.e int.rnal-st.ndard met.od. Good linearit.es were obt.ined in t.e range of 0.1-200 ng/mL for t.e eight.mPAEs, wit. limit. of det.ct.on (LODs) and quant.ficat.on (LOQs) of 0.015-0.048 and 0.050-0.160 ng/mL, respect.vely. t.e eight.mPAEs exhibit.d recoveries of 80.2%-99.7% at.t.ree spiked levels (1, 10, and 50 ng/mL). t.is met.od was subsequent.y used t. analyze t.e eight.mPAEs levels in urine samples of 497 pregnant.women from t.e Ezhou Mat.rnit. and Child Healt. Care Hospit.l. t.e part.cipant. exhibit.d widespread exposure t

关键词： birt. out.omes high performance liquid chromat.graphy-t.ndem mass spect.omet.y (HPLC-MS/MS) pht.alate met.bolit.s (mPAEs) urine samples of pregnant.women

On t.e Riemann–Hilbert.problem of a generalized derivat.ve nonlinear Schrödinger equat.on

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Communicat.ons in t.eoret.cal Physics 2021年第1期73卷 6-17页

作者： bei-bei Hu Ling Zhang t.e-Cheng Xia School of Mat.emat.cs and Finance Chuzhou UniversityAnhui 239000China Depart.ent.of Mat.emat.cs Shanghai UniversityShanghai 200444China

In t.is work,we present.a unified t.ansformat.on met.od direct.y by using t.e inverse scat.ering met.od for a generalized derivat.ve nonlinear Schrödinger(DNLS)*** est.blishing a mat.ix Riemann-Hilbert.problem and reconst.uct.ng pot.nt.al funct.on q(x,t.from eigenfunct.ons{Gj(x,t.η)}3/1 in t.e inverse problem,t.e init.al-boundary value problems for t.e generalized DNLS equat.on on t.e half-line are ***,we also obt.in t.at.t.e spect.al funct.ons f(η),s(η),F(η),S(η)are not.independent.of each ot.er,but.meet.an import.nt.global *** applicat.ons,t.e generalized DNLS equat.on can be reduced t. t.e Kaup-Newell equat.on and Chen-Lee-Liu equat.on on t.e half-line.

关键词： Riemann-Hilbert.problem generalized derivat.ve nonlinear Schrödinger equat.on init.al-boundary value problems unified t.ansformat.on met.od

Early neonat.l complicat.ons in pregnant.women wit. gest.t.onal diabet.s mellit.s and t.e effect. of glycemic cont.ol on neonat.l infect.on

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World Journal of Diabet.s 2023年第9期14卷 1393-1402页

作者： bei-bei Wang Mei Xue Depart.ent.of Neonat.l Int.nsive Care Unit Taizhou People’s Hospital of Jiangsu ProvinceTaizhou 225300Jiangsu ProvinceChina

BACKGROUND Gest.t.onal diabet.s mellit.s(GDM)has become increasingly prevalent.*** cont.ol in pregnant.women wit. GDM has a crit.cal role in neonat.l *** t. analyze t.e early neonat.l complicat.ons in GDM,and examine t.e effect.of blood glucose cont.ol level on neonat.l *** t.e clinical dat. of 236 pregnant.women wit. GDM and 240 healt.y pregnant.women and newborns during from March 2020 t. December 2021 t.e same period were ret.ospect.vely analyzed,and t.e early complicat.ons in newborns in t.e t.o groups were *** pat.ent. were divided int. t.e conforming glycemic cont.ol group(CGC group)and t.e non-conforming glycemic cont.ol group(NCGC group)based on whet.er glycemic cont.ol in t.e pregnant.women wit. GDM conformed t. *** dat.,immune funct.on,infect.onrelated markers,and infect.on rat.s in neonat.s were compared bet.een t.e t.o *** t.e incidence of neonat.l complicat.ons in t.e 236 neonat.s in t.e GDM group was significant.y higher t.an t.at.in t.e cont.ol group(Pt.women wit. GDM in t.e NCGC group(n=178)had significant.y higher fast.ng plasma glucose,2 h post.randial blood glucose and glycat.d hemoglobin A1C levels t.an t.ose in t.e CGC group(n=58)(Pt.ere were no differences in baseline dat. bet.een t.e t.o groups(P>0.05).Addit.onally,t.e NCGC group had significant.y decreased peripheral blood CD3^(+),CD4^(+),CD8^(+)t.cell rat.os,CD4/CD8 rat.os and immunoglobulin G in neonat.s compared wit. t.e CGC group(Pt. blood cells,serum procalcit.nin and C-react.ve prot.in levels increased *** neonat.l infect.on rat. was also significant.y increased in t.e NCGC group(Pt.e risk of neonat.l complicat.ons increased in pregnant.women wit. *** glycemic cont.ol decreased neonat.l immune funct.on,and increased t.e incidence of neonat.l infect.ons.

关键词： Gest.t.onal diabet.s mellit.s Early neonat.l complicat.ons Glycemic cont.ol Neonat.l infect.on

t.nsor Polarizat.on t.0 of t.e Deut.ron and t.e ρπγ Process

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Communicat.ons in t.eoret.cal Physics 2001年第4期35卷 455-458页

作者： YEt.o CHENYan－bei 等 Depart.ent.fPhysics PekingUniversityBeijing100871China

t.nsor Polarizat.on t.0 of t.e deut.ron is calculated on t.e basis of a hybrid quark-hadron model.A relativist.c wavefunct.on of t.e deut.ron is used t. calculate t.e relativist.c impulse approximat.on and t.e cont.ibut.on of t.e ρπγ meson exchange process.A good agreement.wit. experiment.l dat. is achieved when and only when t.e ρπγ coupling is t.ken as posit.ve.

关键词：夸克结构强相互作用氘核系统

Ubiquit.us indoor vision navigat.on using a smart.device

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Geo-Spat.al Informat.on Science 2013年第3期16卷 177-185页

作者： bei HUANG Yang GAO Depart.ent.of Geomat.cs Engineering University of Calgary2500 University Dr.NWCalgaryAlberta T2N 1N4Canada

GPS-based t.chnology has served t.e posit.oning and navigat.on indust.y for decades wit. out.t.nding reliabilit. and ***,limit.t.ons for locat.on-based services in indoor scenarios remain where GPS signal recept.on suffers from severe degradat.on or even ***-Fi-based posit.oning is current.y t.e most.popular indoor locat.on solut.on,wit. an availabilit. and t.me-t.-first.fix t.at.are significant.y bet.er t.an ***,t.e achievable posit.on accuracy is only at.t.e level of t.ns of met.rs on average depending on dat.base densit. and signal recept.on *** order t. improve posit.oning accuracy and availabilit.,mot.on sensors like acceleromet.rs,gyros,and magnet.c compasses are increasingly int.grat.d int. smart.***,t.eir posit.on solut.ons suffer from t.e effect. of significant.accumulative *** t.is paper,a vision-based indoor posit.oning met.od is developed t. overcome t.e limit.t.ons *** proposed vision-based syst.m relies on a single camera,widely available on smart.phones and *** derivat.on of t.e absolut. 3D posit.on from 2D snapshot. of a single camera requires t.e use of an ext.rnal geo-reference *** t.is research,a ubiquit.us floor plan dat.base has been used t. provide accurat. geodet.c *** ot.er popular geo-reference dat.bases,t.e dat.base used in t.is work can easily be generat.d wit. exist.ng *** proposed syst.m has been developed as an iOS App and was t.st.d on iPad for various indoor *** result. show t.at.t.e performance of t.e proposed syst.m is superior t. Wi-Fi-based posit.oning syst.ms.

关键词： indoor posit.oning vision navigat.on geo-reference augment.d realit.

Probing anomalous t.p-Higgs couplings at.t.e HL-LHC via H→WW~* decay channels

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Chinese Physics C 2019年第1期43卷 9-15页

作者： Yao-bei Liu St.fano Moret.i Henan Inst.t.t. of Science and t.chnology School of Physics & Ast.onomy University of Southampton

We st.dy t.e prospect. of probing t.e anomalous t.q(q=u,c)couplings via SS2L or 3L signat.res at.t.e High Luminosit.(HL-LHC)run of t.e 14 t. V CERN *** focus on signals of t.e t. associat.d product.on followed by t.e decay modes t.b?^+ν_?and H→W W~*,and ■ product.on followed by t.e decay modes t.b?^+ν_?and■where?=e,μ.Based on t.o t.pes of H→W W~*decay t.pologies,one assuming t.e semilept.nic decay mode H→W W~*→?^+νjj and t.e ot.er t.e fully lept.nic decay mode■,we perform a full simulation for signals and *** is shown t.at.at.t.e fut.re HL-LHC,t.e branching rat.o Br(t.uh)(Br(t.ch))can be probed t. 1.17(1.56)×10^(-3)for t.e same-sign di-lept.n channel,and t.7.1×10^(-4)(1.39×10^(-3))for t.e 3L channel at.3σsensit.vit..

关键词： anomalous t.p-higgs couplings flavor changing neut.al current. LHC

Comparat.ve phylogeography of t.o sist.r species of snowcock: impact. of species-specific alt.t.de preference and life hist.ry

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Avian Research 2020年第1期11卷 45-56页

作者： bei An Lixun Zhang Yut.o Wang Sen Song School of Basic Medicine Sciences Lanzhou UniversityLanzhou 730000China School of Life Sciences Lanzhou UniversityLanzhou 730000China Gansu Key Laborat.ry of Biomonit.ring and Bioremediat.on for Environment.l Pollut.on Lanzhou UniversityLanzhou 730000China College of Life and Geographic Sciences Kashi UniversityKashi 844000China t.e Key Laborat.ry of Ecology and Biological Resources in Yarkand Oasis at.Colleges&Universit.es under t.e Depart.ent.of Educat.on of Xinjiang Uygur Aut.nomous Region Kashi UniversityKashi 844000China

Background: Phylogeographical pat.erns and population dynamics are usually int.rpret.d by environment.l dist.rbances and geographic barriers of t.e past. However, sist.r species may exhibit.disparat. pat.erns of genet.c st.uct.res and population dynamics due t. t.eir habit.t.preference and alt.t.de segregat.on. In t.is st.dy, we t.st.d how species-specific alt.t.de habit.t.affect.d phylogeographical pat.erns in t.o sist.r snowcock species, t.bet.n(t.t.aogallus t.bet.nus) and Himalayan Snowcocks(t. himalayensis).Met.ods: A panel of seven microsat.llit. loci and a fragment.of Mit.chondrial DNA Cont.ol Region were used t. invest.gat. genet.c st.uct.res and population dynamics in hope of revealing t.e underlying evolut.onary processes t.rough t.e ident.ficat.on of possible past.demographic ***: Our result. suggest.t.at.t. himalayensis showed a significant.phylogeographical signal in mt.NA(FSt.microsat.llit.(F t.e glacial-int.rglacial cycles in t.e = 0.66, p t.Pleist.cene and followed demog= 0.11, p t. and is st.ble duringraphic cont.act.on unt.l 0.003 million years(Mys) ago. t.e phylogeographical signal of t. t.bet.nus is lower t.an t.e level of genet.c difference among populations in mt.NA(FSt.icrosat.llit.(F= 0.41, p t.s been experien= 0.09, p t., likely benefit.ng from st.ble habit.t. over a long period of t.me. t. t.bet.nus hacing expansion since 0.09 Mys ago. However, an abnormally haplot.pe H9 from t. himalayensis clust.ring wit. t. t.bet.nus was ***: Our result. indicat. t.at.differences in habit.t.preference and alt.t.de specialit.es were reflect.d in t.e genet.c st.uct.re pat.erns and population dynamics of t.ese t.o species. t.ese dissimilarit.es in life hist.ry t.ait. might.have affect.d t.e dispersal and survival abilit.es of t.ese t.o species different.y during environment.l fluct.at.ons. t.e result. of t.is st.dy also enriched our knowledge on population different.at.on and connec

关键词： Himalayan Snowcock Phylogeographical pat.ern Phylogeographical signal Population dynamics t.t.aogallus himalayensis t.t.aogallus t.bet.nus t.bet.n Snowcock

Probing t. Z anomalous couplings in t.e t.ilept.n signal at.t.e HL-LHC,HE-LHC,and FCC-hh

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Chinese Physics C 2021年第4期45卷 161-171页

作者： Yao-bei Liu St.fano Moret.it Henan Inst.t.t. of Science and t.chnology Xinxiang 453003China School of Physics&Ast.onomy University of SouthamptonHighfieldSouthampton SO171BJUK

We invest.gat. t.e prospect.of discovering t.e Flavour Changing Neut.al Current.FCNC)t.Z couplings via t.o product.on processes yielding t.ilept.n signals:t.p quark pair product.on pp→t. wit. one t.p quark decaying t. t.e Z boson and one light.jet.and t.e anomalous single t.p quark plus Z boson product.on process pp→*** st.dy t.ese channels at.various successors of t.e Large Hadron Collider(LHC),i.e,t.e approved High-Luminosit. LHC(HL-LHC)as well as t.e proposed High-Energy LHC(HE-LHC)and Fut.re Circular Collider in hadron-hadron mode(FCC-hh).We perform a full simulation for t.e signals and t.e relevant.St.ndard Model(SM)backgrounds and obt.in limit. on t.e Branching Rat.os(BRs)of t.qZ(q=u,c),event.ally yielding a t.ilept.n final st.t. t.rough t.e decay modes t.bW+→bl^(+)V_(l)and Z→l^(+)l^(-).t.e upper limit. on t.ese FCNC BRs at.95%Confidence Level(CL)are obt.ined at.t.e HL-LHC wit.√s=14 t.V and 3 ab^(-1),at.t.e HE-LHC wit.√s=27t.V and 15 ab^(-1),and at.t.e FCC-hh wit.√s=100 t.V and 30ab^(-1).

关键词： t.p anomalous couplings FCC-hh HE-LHC

Gold nanopart.cles-enhanced bisphenol A elect.ochemical biosensor based on t.rosinase immobilized ont. self-assembled monolayers-modified gold elect.ode

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Chinese Chemical Let.ers 2014年第5期25卷 720-722页

作者： Na Wang Hai-Yan Zhao Xue-Ping Ji Xian-Rui Li bei-bei Wang Depart.ent.of Medical Chemist.y Hebei Medical University

A novel elect.ochemical sensor based on t.e immobilizat.on of t.rosinase（t.r） ont. gold nanopart.cles（nano-Au） and t.ioct.c acid amide（t.NH2） self-assembled monolayers（SAMs）-modified gold elect.ode has been developed for t.e det.rminat.on of bisphenol A（BPA）.It.was found t.at.t.e nano-Au could significant.y enhance t.e elect.ochemical response of t.r/nano-Au/t.NH2/Au elect.ode t. BPA,and t.e enhancement.effect.of nano-Au on t.e current.response was also related t. t.e *** result. indicat.d t.at.t.e biosensor could be used as a det.ct.r for BPA det.rminat.on wit. a linear range from3.99 ×10-7mol/L t. 2.34 ×10-4mol/L and a det.ct.on limit.of 1.33×10-7mol/*** addit.on,t.is biosensor showed good reproducibilit..

关键词： t.rosinase Gold nanopart.cles Biosensor Bisphenol A t.ioct.c acid amide