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Early identification of stroke through deep learning with multi-modal human speech and movement data

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Neural Regeneration Research 2025年第1期20卷 234-241页

作者： Zijun Ou Haitao Wang Bin Zhang Haobang Liang bei hu Longlong Ren Yanjuan Liu Yuhu Zhang Chengbo Dai Hejun Wu Weifeng Li Xin Li School of Computer Science and Engineering Sun Yat-sen UniversityGuangzhouGuangdong ProvinceChina Department of Neurology Guangdong Neuroscience InstituteGuangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhouGuangdong ProvinceChina Department of Emergency Medicine Guangdong Provincial People’s Hospital(Guangdong Academy of Medical Sciences)Southern Medical UniversityGuangzhouGuangdong ProvinceChina

Early identification and treatment of stroke can greatly improve patient outcomes and quality of *** clinical tests such as the Cincinnati Pre-hospital Stroke Scale(CPSS)and the Face Arm Speech Test(FAST)are commonly used for stroke screening,accurate administration is dependent on specialized *** this study,we proposed a novel multimodal deep learning approach,based on the FAST,for assessing suspected stroke patients exhibiting symptoms such as limb weakness,facial paresis,and speech disorders in acute *** collected a dataset comprising videos and audio recordings of emergency room patients performing designated limb movements,facial expressions,and speech tests based on the *** compared the constructed deep learning model,which was designed to process multi-modal datasets,with six prior models that achieved good action classification performance,including the I3D,SlowFast,X3D,TPN,TimeSformer,and *** found that the findings of our deep learning model had a higher clinical value compared with the other ***,the multi-modal model outperformed its single-module variants,highlighting the benefit of utilizing multiple types of patient data,such as action videos and speech *** results indicate that a multi-modal deep learning model combined with the FAST could greatly improve the accuracy and sensitivity of early stroke identification of stroke,thus providing a practical and powerful tool for assessing stroke patients in an emergency clinical setting.

关键词： artificial intelligence deep learning diagnosis early detection FAST screening stroke

新型研发机构功能定位的实现机制研究——以北京为例

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科学学研究 2024年第3期42卷 563-570页

作者：于贵芳胡贝贝王海芸北京市科学技术研究院北京100089 中国科学院科技战略咨询研究院北京100190

新型研发机构作为一种新的研发组织形式,正逐步成为创新驱动发展的新生力量。文章从知识协同视角构建了包括机制层、目标层、功能层三方面的新型研发机构功能定位实现机制理论模型,并以北京为例,从中选取北京智源人工智能研究院等3个代... 详细信息

新型研发机构作为一种新的研发组织形式,正逐步成为创新驱动发展的新生力量。文章从知识协同视角构建了包括机制层、目标层、功能层三方面的新型研发机构功能定位实现机制理论模型,并以北京为例,从中选取北京智源人工智能研究院等3个代表性新型研发机构,对其功能定位的实现机制进行了多案例分析,研究发现:新型研发机构通过一系列内部治理机制创新,突破创新协同中的知识流动障碍,支撑其基础研究、应用研究到成果转化集成功能的实现。基于此提出应进一步促进多元主体参与新型研发机构创新,进一步创新管理机制保障新型研发机构成果转化应用等政策启示。

关键词：新型研发机构功能定位实现机制

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信用等级变换的自由边界问题

中国科学：数学 2024年第3期54卷 285-312页

作者：陈新富胡钡梁进尹洪明 Department of Mathematics University of PittsburghPittsburghPA 15260USA Department of Applied and Computational Mathematics and Statistics University of Notre DameNotre DameIN 46556USA 同济大学数学科学学院上海200092 Department of Mathematics and Statistics Washington State UniversityPullmanWA 99164USA

本文总结近年来评估信用等级变换风险的结构化模型的建立和发展,特别关注了使用资产债务比划分高低等级并且不同等级的资产满足不同的随机过程的情形,而这个问题可以转化为自由边界问题.本文介绍关于这个模型的理论研究结果、计算和实... 详细信息

本文总结近年来评估信用等级变换风险的结构化模型的建立和发展,特别关注了使用资产债务比划分高低等级并且不同等级的资产满足不同的随机过程的情形,而这个问题可以转化为自由边界问题.本文介绍关于这个模型的理论研究结果、计算和实证方法以及模型的一些推广和展望.

关键词：信用等级变换信用风险评估自由边界金融数学

On the Riemann–Hilbert problem of a generalized derivative nonlinear Schrödinger equation

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Communications in Theoretical Physics 2021年第1期73卷 6-17页

作者： bei-bei hu Ling Zhang Tie-Cheng Xia School of Mathematics and Finance Chuzhou UniversityAnhui 239000China Department of Mathematics Shanghai UniversityShanghai 200444China

In this work,we present a unified transformation method directly by using the inverse scattering method for a generalized derivative nonlinear Schrödinger(DNLS)*** establishing a matrix Riemann-Hilbert problem and reconstructing potential function q(x,t)from eigenfunctions{Gj(x,t,η)}3/1 in the inverse problem,the initial-boundary value problems for the generalized DNLS equation on the half-line are ***,we also obtain that the spectral functions f(η),s(η),F(η),S(η)are not independent of each other,but meet an important global *** applications,the generalized DNLS equation can be reduced to the Kaup-Newell equation and Chen-Lee-Liu equation on the half-line.

关键词： Riemann-Hilbert problem generalized derivative nonlinear Schrödinger equation initial-boundary value problems unified transformation method

The study of electrochemical cycle for LiCoO_(2) by dual-mode EPR

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Magnetic Resonance Letters 2023年第1期3卷 61-66,I0003页

作者： bei hu Fushan Geng Ming Shen Bingwen hu Shanghai Key Laboratory of Magnetic Resonance State Key Laboratory of Precision SpectroscopySchool of Physics and Electronic ScienceEast China Normal UniversityShanghai200241China

Dual-mode electron paramagnetic resonance(EPR)spectroscopy was employed to analyze redox mechanisms in lithium cobalt oxide LiCoO_(2)(LCO)cathode material during delithiation and *** was found that the O_(3)-II could not fully convert back to the pristine O_(3) -I phase while oxygen vacancies quickly generate and accumulate during the *** study paves the way for better understanding the doping effects of different elements on LiCoO_(2) in the future.

关键词： LiCoO_(2) EPR Redox mechanism Lithium-ion battery

超高效液相色谱-串联质谱法快速测定化妆品中87种禁用原料

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色谱 2024年第1期42卷 38-51页

作者：胡贝李丽霞丁晓萍刘红黄伟吕稳李晓健湖北省药品监督检验研究院湖北省药品质量检测与控制工程技术研究中心湖北武汉430075

建立了超高效液相色谱-串联质谱测定化妆品中87种禁用原料的方法,其适用于水基类、乳液膏霜类和油基类3种常见化妆品基质。实验对提取溶剂、提取时间及色谱、质谱条件进行了考察。水基类和乳液膏霜类化妆品用乙腈分散、50%乙腈水溶液超... 详细信息

建立了超高效液相色谱-串联质谱测定化妆品中87种禁用原料的方法,其适用于水基类、乳液膏霜类和油基类3种常见化妆品基质。实验对提取溶剂、提取时间及色谱、质谱条件进行了考察。水基类和乳液膏霜类化妆品用乙腈分散、50%乙腈水溶液超声提取,油基类化妆品用正己烷分散、70%乙腈水溶液涡旋提取;采用CORTECS C18色谱柱(150 mm×2.1 mm,2.7μm)进行分离,以乙腈和0.1%甲酸水溶液为流动相进行梯度洗脱,流速为0.3 mL/min,柱温为40℃,进样量为2μL。采用电喷雾电离(ESI)源,在多反应监测(MRM)模式下采集数据,利用基质匹配标准曲线进行定量分析。结果表明,87种禁用原料在各自的线性范围内具有良好的线性关系,相关系数(r)>0.99,检出限(LOD)为0.07~0.38μg/g,定量限(LOQ)为0.21~1.15μg/g。3种化妆品基质中87种禁用原料在低、中、高3个加标水平下的加标回收率为81.7%~115.4%,相对标准偏差(RSD,n=6)为0.4%~9.9%。采用该方法对349批化妆品样品进行测定,共发现8批阳性样品,检出成分分别为甲氧苄啶、特比萘芬、萘甲唑啉、7-甲氧基香豆素和7-甲基香豆素。本方法前处理过程简便,定性、定量可靠,可用于测定化妆品中87种禁用原料,能够为化妆品的快速风险筛查和国家标准的制修订提供技术支撑。

关键词：超高效液相色谱-串联质谱禁用原料化妆品

Synthesis and properties of a novel bolaamphiphile surfactant derived from proline

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Chinese Chemical Letters 2016年第3期27卷 447-450页

作者： bei-bei hu Yue Yuan Xiao-Ping Zhou San-Ming Li School of Pharmacy Shenyang Pharmaceutical University Shenyang 110016 China School of Pharmacy Jilin University Changchun 130021 China

A novel bolaamphiphile surfactant N,N0-（octane-1,8-diyl）bis（pyrrolidine-2-carboxamide）（DAOP）, was designed and synthesized from proline and 1,8-diaminooctane, as the hydrophilic part and hydrophobic part, respectively. After separation and purification, the structures of the synthesized bola surfactants were verified by IR, MS and-1 H NMR. The p Kawas measured by a titration experiment, the turbidity was determined using a Shimadzu UV-1750 spectrophotometer, and the critical micelle concentration（CMC）values of the synthesized surfactants in water were obtained using the conductivity and fluorescence probe measurements. The synthesized bolaamphiphile surfactants demonstrate the ability of selfassemble to form vesicles that were confirmed with dynamic light scattering and transmission electron microscopy. The results showed that the novel bolaamphiphile surfactant derived from proline might potentially be an excellent carrier for drug delivery.

关键词： Bolaamphiphile Proline Vesicles Synthesis Physicochemical characterization

某核电站核废物厂房通风系统设计特性与模拟研究

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暖通空调 2024年第1期54卷 10-15页

作者：刘婧胡北王楷乔张艳刚中国核电工程有限公司北京

核废物厂房具有工艺房间种类多、辐射分区齐全、建筑体量大的特点,其通风系统功能多样、设计复杂、系统庞大。本文介绍了核废物厂房包含的各通风子系统,针对冷负荷强度较高的电气设备间进行了温度场和速度场模拟,提出了风口布置需注意... 详细信息

核废物厂房具有工艺房间种类多、辐射分区齐全、建筑体量大的特点,其通风系统功能多样、设计复杂、系统庞大。本文介绍了核废物厂房包含的各通风子系统,针对冷负荷强度较高的电气设备间进行了温度场和速度场模拟,提出了风口布置需注意的事项;研究了狭窄工艺隔间的流速场,验证了气流组织的合理性。给出了通风系统设计的优化方向,为后续工程设计提供参考。

关键词：核电站核废物厂房通风系统气流组织温度速度

Effect of Particle＇s Size on the Structural and Dynamical Properties in 2D Dusty Plasma

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Communications in Theoretical Physics 2007年第3期47卷 569-572页

作者： KONG Wei WANG Xin LIU Song-Fen hu bei-Lai WANG Long Department of Physics Nankai University Tianjin 300071 China Institute of Physics the Chinese Academy of Sciences Beijing 100080 China

In a two-dimensional （219） dusty plasma system, the size of particles is considered under two different interparticle potentials （Yukawa potential and Dressed potential）. The structural and dynamical characters are investigated by molecular dynamics simulation respectively. The results show that the 2D systems via Yukawa and Dressed potentials have a different critical coupling constant F corresponding to the systems beginning to coagulate and exhibit different crystal configurations. Also we find that the size of particles has little influence on the 2D system＇s structure characters.

关键词： 2D dusty plasma Yukawa potential dressed potential