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Microstructural characteristics and mechanical properties of Al-2024 alloy processed via a rheocasting route

International Journal of Minerals,Metallurgy and Materials 2015年第1期22卷 59-67页

作者： behnam rahimi Hamed Khosravi Mohsen Haddad-Sabzevar Department of Metallurgy and Materials Engineering Faculty of EngineeringFerdowsi University of Mashhad Faculty of Materials Science and Engineering K.N.Toosi University of Technology

This article reports the effects of stirring speed and T6 heat treatment on the microstructure and mechanical properties of Al-2024 alloy synthesized by a rheocasting process. There was a decrease in grain size ofα-Al particles corresponding to an increase in stirring speed. By increasing the stirring speed, however, the globularity of matrix particles first increased and then declined. It was also found that the hardness, compressive strength, and compressive strain increased with the increase of stirring speed. Microstructural studies revealed the presence of nonsoluble Al15（CuFeMn）3Si2 phase in the vicinity of CuAl2 in the rheocast samples. The required time for the solution treatment stage was also influenced by stirring speed;the solution treatment time decreased with the increase in stirring speed. Furthermore, the rheo-cast samples required a longer homogenization period compared to conventionally wrought alloys. Improvements in hardness and compres-sive properties were observed after T6 heat treatment.

关键词： aluminum alloys rheocasting microstructure mechanical properties

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Evaluating the safety and efficacy of mesenchymal stem cell-derived exosomes for treatment of refractory perianal fistula in IBD patients:clinical trial phaseⅠ

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Gastroenterology Report 2022年第1期10卷 585-593页

作者： Hojjatollah Nazari Foroogh Alborzi Asieh Heirani-Tabasi Alireza Hadizadeh Reza Akbari Asbagh behnam Behboudi Mohammad Sadegh Fazeli Mojgan rahimi Mohammad Reza Keramati Amir Keshvari Alireza Kazemeini Masoud Soleimani Seyed Mohsen Ahmadi Tafti Department of Colorectal Surgery Colorectal Research CenterImam Khomeini Hospital ComplexTehran University of Medical SciencesTehranIran Department of Biomedical Engineering School of Biomedical EngineeringUniversity of Technology SydneySydneyNSWAustralia Department of Gastroenterology Division of GastroenterologyImam Khomeini HospitalSchool of MedicineTehran University of Medical SciencesTehranIran Department of Cardiovascular Surgery Research Center for Advanced Technologies in Cardiovascular MedicineCardiovascular Research InstituteTehran University of Medical SciencesTehranIran Division of Colorectal Surgery Department of SurgeryTehran University of Medical SciencesTehranIran Department of Cell Therapy and Hematology Faculty of Medical SciencesTarbiat Modares UniversityTehranIran Department of Tissue Engineering and Applied Cell Sciences School of Advanced Technologies in MedicineStudent Research CommitteeShahid Beheshti University of Medical SciencesTehranIran

Background:Exosome administration is a novel medical approach that promises excellent immunomodulatory properties without the conventional side effects of current antitumor necrosis factor drugs and *** study aimed to assess the safety and efficacy of usingmesenchymal stemcell(MSC)exosomes to treat refractory fistulas in patients with inflammatory bowel ***:MSCs were derived from the umbilical cords and their exosomes were *** patients with refractory perianal Crohn’s disease fistulas with amedian age of 35 years(range 31–47 years)were enrolled in the *** injections were administered in the operating roomto patients with refractory fistula(fistulas that are irresponsive to anti-tumor necrosis factor-αadministration within 6months).Sixmonths later,a physical examination,face-to-face interviews,andmagnetic resonance imaging were employed to evaluate the therapy responses of ***:The outcomes within 6 months after initiation of therapy showed that four patients had responded to *** patients who received exosome injections exhibited complete healing,while one reported no improvement and active discharge from the fistula *** addition,five patients(100%)reported neither systemic nor local adverse ***:Injection of exosomes extracted from MSCs demonstrates safety and a satisfactory therapeutic effect,as evidenced in this and other studies,and may play a significant role in the future treatment of gastrointestinal fistulas.

关键词： IBD exosome Crohn’s disease MSCs fistula

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Post-discharge follow-up of patients with spine trauma in the National Spinal Cord Injury Registry of Iran during the COVID-19 pandemic:Challenges and lessons learned

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Chinese Journal of Traumatology 2024年第3期27卷 173-179页

作者： Zahra Azadmanjir Moein Khormali Mohsen Sadeghi-Naini Vali Baigi Habibollah Pirnejad Mohammad Dashtkoohi Zahra Ghodsi Seyed behnam Jazayeri Aidin Shakeri Mahdi Mohammadzadeh Laleh Bagheri Mohammad-Sajad Lotfi Salman Daliri Amir Azarhomayoun Homayoun Sadeghi-Bazargani Gerard O'reilly Vafa rahimi-Movaghai Health Information Management Department School of Allied Medical SciencesTehran University of Medical SciencesTehranIran Sina Trauma and Surgery Research Center Tehran University of Medical SciencesTehranIran Department of Neurosurgery Lorestan University of Medical SciencesKhoram-AbadIran Department of Epidemiology and Biostatistics School of Public HealthTehran University of Medical SciencesTehranIran Patient Safety Research Center Clinical Rsearch Institute Urma Universty of Medical SciencesUrmaIran Erasmus School of Health Policy&Management(ESHPM) Erasmus University RotterdamRoterdamthe Netherlands Brain and Spinal Cord Injury Research Center Neuroscience InstituteTehran University of Medical SciencesTehranIran Students Scientifc Research Center(SSRC) Tehran University of Medical SciencesTehranIran Department of Neurosurgery Arak University of Medical SciencesArakIran Trauma Research Center Kashan University of Medical SciencesKashanIran Shahid Rahnemoun Hospital Shahid Sadoughi University of Medical SciencesYazdIran Trauma Nuring Rearch entre Faculty of Nursing and Midwifry Kahan Universty of Medical Sciences Kahan Iran Clinical Research Development Unit Imam Hossein HospitalShahroud University of Medical SciencesShahroudIran Research Center for Evidence Based Medicine Faculty of MedicineTabriz University of Medical SciencesTabrizIran Road Trafic Injury Research Center Tabriz University of Medical SciencesTabrizIran School of Public Health and Preventive Medicine Monash UniversityMelbourneAustralia National Trauma Research Institute The AlfredMelbourneAustralia Department of Neurosurgery Shariati HospitalTehran University of Medical SciencesTehranIran Universal Scientific Education and Research Network(USERN) TehranIran Institute of Biochemistry and Biophysics University of TehranTehranIran

Purpose:The purpose of the National Spinal Cord Injury Registry of Iran(NSCIR-IR)is to create an infrastructure to assess the quality of care for spine trauma and in this study,we aim to investigate whether the NSCIR-IR successfully provides necessary post-discharge follow-up data for these ***:An observational prospective study was conducted from April 11,2021 to April 22,2022 in 8 centers enrolled in NSCIR-IR,respectively Arak,Rasht,Urmia,Shahroud,Yazd,Kashan,Tabriz,and *** were classified into 3 groups based on their need for care resources,respectively:(1)non-spinal cord injury(SCI)patients without surgery(group 1),(2)non-SCI patients with surgery(group 2),and(3)SCI patients(group 3).The assessment tool was a self-designed questionnaire to evaluate the care quality in 3 phases:pre-hospital,in-hospital,and *** data from the first 2 phases were collected through the *** post-hospital data were collected by conducting follow-up *** follow-ups were conducted for groups 1 and 2(non-SCI patients),while group 3(SCI patients)had a face-to-face *** study took place during the COVID-19 *** on age and time interval from injury to follow-up were expressed as mean±standard deviation(SD)and response rate and follow-up loss as a ***:Altogether 1538 telephone follow-up records related to 1292 patients were registered in the *** the total calls,918(71.05%)were related to successful follow-ups,but 38 cases died and thus were excluded from data *** the end,post-hospital data from 880 patients alive were *** success rate of follow-ups by telephone for groups 1 and 2 was 73.38%and 67.05%respectively,compared to 66.67%by face-to-face visits for group 3,which was very hard during the COVID-19 *** data completion rate after discharge ranged from 48%-100%,22%-100%and 29%-100%for groups ***:To improve patient accessibility,NSCIR-IR should take me

关键词： Follow-up studies Spinal injuries Spinal cord injuries COVID-19 NSCIR-IR

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