检索结果-南通市图书馆

Phytochemical Loaded Nanovehicles of Biopolymer for Breast Cancer:A Systemic Review

Clinical Complementary Medicine and Pharmacology 2023年第4期3卷 60-78页

作者： Vivek P.Chavda Suneetha Vuppu Rajashri Bezbaruah Lakshmi Vineela Nalla Siva Nageswara Rao Gajula Pankti C.Balar Toshika Mishra Nikita Sharma Sathvika Kamaraj Thushar Suresh Anand Sairam bedanta bhattacharjee Department of Pharmaceutics and Pharmaceutical Technology LM College of PharmacyAhmedabadGujarat 380009India Department of Biotechnology ScienceInnovationand Society Research lab 115Hexagon(SMV)Vellore Institute of TechnologyVelloreTamil Nadu 632014India Institute of Pharmacy Assam Medical College and HospitalDibrugarhAssam 786002India Department of Pharmaceutical Science Faculty of Science and EngineeringDibrugarh UniversityDibrugarhAssam 786004India Department of Pharmacy Koneru Lakshmaiah Education FoundationVaddeswaramAndhra PradeshIndia Department of Pharmaceutical Analysis GITAM School of PharmacyGITAM(Deemed to be University)RushikondaVisakhapatnamAndhra Pradesh 530045India Pharmacy Section LM College of PharmacyAhmedabadGujarat 380009India Departemnt of Pharmacology and Toxicology Girijananda Chowdhury Institute of Pharmaceutical Science-TezpurSonitpurAssam 784501India

Background:Breast cancer is one of the most common malignancies affecting women worldwide,emphasizing the need for effective therapeutic *** derived from plants have gained significant attention due to their potential anticancer ***:This review aims to comprehensively assess the existing literature on using phytochemical-loaded for-mulations as a therapeutic approach for breast *** analyzing the available evidence,we aim to determine the potential benefits and limitations of these formulations in terms of their anticancer activity,bioavailability,and ***:A systematic search of relevant databases was conducted to identify studies investigating phytochemical-loaded formulations in the context of breast cancer *** inclusion criteria encompassed clinical trials,preclinical studies,and in-vitro experiments that reported using phytochemicals in various formulations for breast cancer *** extraction was performed to ensure the reliability and validity of the included ***:The review highlights the diverse range of phytochemicals used in different formulations for breast cancer *** suggest that these formulations exhibit promising anticancer effects by targeting mul-tiple signaling pathways in breast cancer progression,including cell proliferation,apoptosis,angiogenesis,and ***,various delivery systems,such as nanoparticles,liposomes,and micelles,have enhanced phytochemicals’bioavailability and targeted ***:Phytochemical-loaded formulations hold immense potential as a therapeutic approach for breast cancer *** reviewed evidence indicates their ability to inhibit tumor growth,enhance chemotherapy effectiveness,and reduce adverse ***,further research is warranted to optimize the formulation strategies,investigate the long-term safety profiles,and conduct large-scale clinical trials to establish their efficacy and applicabi

关键词： Breast cancer Cancer Phytochemicals Nanocerriers Nanoparticles

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Viability of a concentrated solar power system in a low sun belt prefecture

引用

Frontiers in Energy 2020年第4期14卷 850-866页

作者： Rahul bhattacharjee Subhadeep bhattacharjee Department of Electrical Engineering National Institute of Technology(NIT)AgartalaTripura Pin-799046India

Concentrating solar power(CSP)is considered as a comparatively economical,more efficient,and large capacity type of renewable energy ***,CSP generation is found restricted only to high solar radiation belt and installed where high direct normal irradiance is *** paper examines the viability of the adoption of the CSP system in a low sun belt region with a lower direct normal irradiance(DNI).Various critical analyses and plant economics have been evaluated with a lesser DNI *** obtained results out of the designed system,subjected to low DNI are not found below par,but comparable to some extent with the performance results of such CSP plants at a higher *** analysis indicates that incorporation of the thermal energy storage reduces the levelized cost of energy(LCOE)and augments the plant capacity *** capacity factor,the plant efficiency,and the LCOE are found to be 32.50%,17.56%,and 0.1952$/kWh,respectively.

关键词： concentrated solar power direct normal irradiance plant performance plant economics thermal energy storage

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

A survey of density based clustering algorithms

引用

Frontiers of Computer Science 2021年第1期15卷 139-165页

作者： Panthadeep bhattacharjee Pinaki MITRA Department of Computer Science and Engineering Indian Institute of TechnologyGuwahati 781039India

Density based clustering algorithms(DBCLAs)rely on the notion of density to identify clusters of arbitrary shapes,sizes with varying *** surveys on DB-CLAs cover only a selected set of *** surveys fail to provide an extensive information about a variety of DBCLAs proposed till date including a taxonomy of the *** this paper we present a comprehensive survey of various DB-CLAS over last two decades along with their *** group the DBCLAs in each of the four categories:density definition,parameter sensitivity,execution mode and nature of*data and further divide them into various classes under each of these *** addition,we compare the DBCLAs through their common features and variations in citation and conceptual *** identify various application areas of DBCLAS in domains such as astronomy,earth sciences,molecular biology,geography,*** survey also identifies probable future directions of DBCLAs where involvement of density based methods may lead to favorable results.

关键词： clustering density based clustering survey classification common properties applications

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Accumulation of Polyphenolic Compounds and Osmolytes under Dehydration Stress and Their Implication in Redox Regulation in Four Indigenous Aromatic Rice Cultivars

引用

Rice science 2020年第4期27卷 329-344页

作者： Nivedita DEY Soumen bhattacharjee Plant Physiology and Biochemistry Research Laboratory/University Grants Commission Centre for Advanced Study Department of BotanyUniversity of BurdwanBurdwan 713104West BengalIndia

Present work was undertaken to screen some drought tolerant indigenous aromatic rice cultivars(IARCs),commonly cultivated in West Bengal,India,based on their capacity to produce osmolytes,redox-sensitive phenolic acids and flavonoids,as contrivances for redox-regulation under drought *** glycol induced post imbibitional dehydration stress mediated changes in redox regulatory properties of the germinating seeds of the four IARCs(Jamainadu,Tulaipanji,Sitabhog,Badshabhog),which were assessed in terms of changes in prooxidant accumulation(in-situ localization of reactive oxygen species(ROS)by confocal microscopy,DCFDA(2′,7′-dichlorofluorescin diacetate)oxidation,O2-and H2O2 accumulation),cumulative antioxidative defense(radical scavenging property and total thiol content),ROS scavenging phenolic acids(gallic acid,protocatechuic acid,gentisic acid,para-hydroxy benzoic acid,chlorogenic acid,caffeic acid,syringic acid,salicylic acid,sinapic acid and p-coumaric acid)and flavonoids(catechin,naringin,rutin,quercetin,kaempferol,myricetin and apigenin).The capability of germinating seeds to accumulate osmolytes(like glycinebetaine,proline,soluble carbohydrates and K+ion)and polyphenolic compounds was also correlated with their corresponding redox status and redox biomarkers(conjugated diene,hydroperoxide,thiobarbituric acid reactive substances and free carbonyl content)produced under the same *** results in general showed that accumulation of osmolytes along with the redox-sensitive phenolics and flavonoids conferred the ability to maintain the redox homeostasis under drought stress for the tolerant IARCs(Badshabhog and Tulaipanji).

关键词： aromatic rice drought polyphenolic compounds osmolytes redox regulation

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

An HESS Based on a Modified MMCC-TSBC Converter Integrating Energy Storages

引用

CSEE Journal of Power and Energy Systems 2023年第5期9卷 1698-1709页

作者： Prabir Ranjan Kasari Subhadeep bhattacharjee the Department of Electrical Engineering of National Institute of Technology Agartala AgartalaTripura 799046India

This paper presents a modified modular multilevel cascaded converter based on a triple star bridge cell(MMCCTSBC)for integrating different types of energy storage to form a hybrid energy storage system(HESS).The proposed HESS comprises battery energy storage,supercapacitor energy storage and a doubly-fed induction machine(DFIM)based variable speed pump storage(VSPS).Different low-rated energy storage units can be intermixed in this converter to form an *** is possible due to the modular structure of the modified converter and provides an advantage in a high-power energy storage *** validate the performance of HESS,real-time power variation data is accumulated from online sources and a weighted median filter(WMF)is employed for generating appropriate references for battery energy storage system(BESS)and supercapacitor storage to mitigate both low frequency and high-frequency power ***,the control approach permits independent regulation of grid current and DFIM current through the modified MMCC-TSBC *** simulation and experimental results validate the effectiveness of the control scheme for the proposed HESS.

关键词： BESS DFIM MMCC supercapacitor storage,TSBC converter VSPS

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Large-scale microfluidic gradient arrays reveal axon guidance behaviors in hippocampal neurons

引用

Microsystems & Nanoengineering 2017年第1期3卷 302-315页

作者： Nirveek bhattacharjee Albert Folch Department of Bioengineering University of Washington372015th Ave NEFoege N423-ASeattleWA 98195USA

High-throughput quantitative approaches to study axon growth behaviors have remained a *** have developed a 1024-chamber microfluidic gradient generator array that enables large-scale investigations of axon guidance and growth dynamics from individual primary mammalian neurons,which are exposed to gradients of diffusible *** microfluidic method(a)generates statistically rich data sets,(b)produces a stable,reproducible gradient with negligible shear stresses on the culture surface,(c)is amenable to the long-term culture of primary neurons without any unconventional protocol,and(d)eliminates the confounding influence of cell-secreted *** this platform,we demonstrate that hippocampal axon guidance in response to a netrin-1 gradient is concentration-dependent—attractive at higher concentrations and repulsive at lower *** also show that the turning of the growth cone depends on the angle of incidence of the *** study highlights the potential of microfluidic devices in producing large amounts of data from morphogen and chemokine gradients that play essential roles not only in axonal navigation but also in stem cell differentiation,cell migration,and immune response.

关键词： axon guidance microfluidic gradient microjet netrin-1 primary mammalian neuron

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

iMass:an approximate adaptive clustering algorithm for dynamic data using probability based dissimilarity

引用

Frontiers of Computer Science 2021年第2期15卷 189-191页

作者： Panthadeep bhattacharjee Pinaki MITRA Department of Computer Science and Engineering Indian Institute of TechnologyGuwahati781039India

1 Research goals The primary goal of this work is to propose an approximate incremental solution to MBSCAN[1]known as the iMass clustering algorithm for processing point wise insertions dynamically(Table 1,Fig.1).MBSCAN acts as a robust baseline because it replaces distance based density measure of DBSCAN[2]by a mass-based[3,4]approach.

关键词： DBSCAN CAN approximate

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Drosophila melanogaster as an indispensable model to decipher the mode of action of neurotoxic compounds

引用

BIOCELL 2023年第1期47卷 51-69页

作者： MONALISA MISHRA PUNYATOYA PANDA bedanta KUMAR BARIK AMRITA MONDAL MRUTUNJAYA PANDA Neural Developmental Biology Lab Department of Life ScienceNIT RourkelaRourkela769008India Centre for Nanomaterials NIT RourkelaRourkela769008India

Exposure to some toxic compounds causes structural and behavioral anomalies associated with the neurons in the later stage of *** toxic compounds are termed as a neurotoxicant,which can be a physical factor,a toxin,an infection,radiation,or maybe a *** incongruities caused due to a neurotoxicant further depend on the toxicity of the *** importantly,the neurotoxicity of the compound is associated with the concentration and the time point of *** neurodevelopmental defect appears depending on the toxicity of the compound.A neurodevelopmental defect may be associated with a delay in developmental time,defective growth,structural abnormality of many organs,including sensory organs,behavioral abnormalities,or death in the fetus *** model organisms are employed to assess the effect of *** current review summarizes several methods used to check the effect of neurotoxicant and their effect using the model organism Drosophila melanogaster.

关键词： Developmental cycle Drug metabolism Neurotoxicity Neurotoxicants Complex behavioral assay Stress enzymes

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Modeling and computation by artificial neural network of fracture toughness of low alloy steel to study the effect of alloy composition

引用

International Journal of Modeling, Simulation, and Scientific Computing 2018年第6期9卷 43-56页

作者： Subir Paul Shibasish bhattacharjee Department of Metallurgical and Material Engineering Jadavpur University Kolkata India

The unpredictable structure failures of carbon steel and low alloy steel leading to accidents may be caused by the propagation of a flaw or crack already present in the *** toughness which describes the ability of a material containing a crack to resist fracture is one of the most important material properties for design applications of metallic *** this material property is influenced by several parameters,namely material chemistry,heat treatment,morphology of structure,it requires millions of experiments to be conducted to understand and predict ***,mathematical modeling is one of the solutions to find the effect of these parameters and design future ***–intensity factor(KIC)is a quantitative parameter of fracture toughness determining a maximum value of stress which may be applied to a specimen containing a crack(notch)of a certain *** artificial neural network(ANN)model was developed using over 100 sets of data to study the effect of alloying elements on fracture toughness,KIC for the low alloy steel.20%of data was used for training,60%to develop predictive model and rest of the 20%for *** model can predict the fracture toughness of unknown new data close to 80%accuracy which is good enough for statistical *** details of program code with ANN modeling steps have been *** of fracture toughness by the model with variation of alloy composition as well as yield stress gives interesting and important information which may help in designing alloy which will resist crack propagation in a structure and hence enhance the life of structure to fail.

关键词： Stress-intensity factor fracture toughness low alloy steel alloying elements ANN modeling prediction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Bioactive polyphenolic compounds, water-soluble vitamins, in vitro anti-inflammatory, anti-diabetic and free radical scavenging properties of underutilized alternate crop Amaranthus spinosus L. from Gangetic plain of West Bengal

引用

Food Bioscience 2022年第6期50卷 799-813页

作者： Agnideepa Kar Soumen bhattacharjee Plant Physiology&Biochemistry Research laboratory UGC Centre for Advanced StudyDepartment of BotanyThe University of BurdwanBurdwanWest BengalIndia UGC Centre for Advanced Study Department of BotanyThe University of BurdwanBurdwanWest BengalIndia

Studies associated with validation of folklore and ethnomedicinal claim of utilization of different plant parts of ‘ spiny amaranth’ (Amaranthus spinosus L.) against degenerative diseases with chemical data, particularly the bioactive polyphenolic compounds and associated anti-degenerative properties are scanty and is the purpose of the present investigations. RP-HPLC coupled photodiode assay was employed for the quantification of twenty-one health promoting bioactive polyphenolic antioxidants derived from phenylpropanoid pathway from different plant parts of Amaranthus spinosus L. for validating organoleptic traditional claims as well as current trends in practice of this underutilized medicinal herb. Further, important water-soluble vitamins [vitamin B1, B2, B3, B6, B9] present in different plant parts were extracted and estimated through RP-HPLC for validating the claim of their functional food properties. The antioxidant-based functional food property of different plant parts of Amaranthus spinosus were corroborated from the data of in vitro free radical scavenging, metal-chelating, reducing, superoxide radical scavenging, hydroxyl radical scavenging, anti-protein coagulation, anti-lipid peroxidation and antidiabetic properties. When compared, a positive correlation in accumulation of polyphenolic compounds and water-soluble vitamins tested with antioxidant attributes were noticed for different plant parts, strongly substantiating their phytonutrient properties. Taken as a whole, the present work provides data on organ-specific bioavailability of bioactive polyphenolic antioxidant compounds, water soluble B- vitamins and their functional attributes for validating traditional claims as well as existing trends in consumption of this underutilized medicinal vegetable as low-cost natural antioxidant supplement and functional food, which may encourage their effective exploration and utilization.

关键词： Spiny amaranth Bioactive polyphenolic compounds B-Vitamins Antioxidant and anti-inflammatory properties Ethnomedicinal use Functional food

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：