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Prevalence of Renal Failure in Children and the Need for Dialysis in Paediatric Nephrology in a Developing Country

Open Journal of Nephrology 2022年第1期12卷 101-111页

作者： Younoussa Keita Aliou A. Ndongo Fatou Ly Ndeye C. Cisse Liliane N. D. M. Yamba Babacar Niang Djiby Seck Amadou Sow Ndeye F. Sow Abou Ba Indou D. Ly Aliou Thiongane Amadou L. fall Idrissa D. Ba Modou Gueye Pape M. Faye Assane Sylla Pediatric Unit of Aristide Le Dantec Hospital Dakar Senegal Pediatric Unit of Pikine Hospital Dakar Senegal Pediatric Unit of Albert Royer Hospital Dakar Senegal Pediatric Unit of Abass Ndao Hospital Dakar Senegal Pediatric Unit of Dalal Diam Hospital Dakar Senegal

Background: Renal failure is among the major visceral failures responsible for morbidity and mortality in children. Epidemiological data on renal failure in children are limited in sub-Saharan Africa, including Senegal. We conducted this study to assess the prevalence of renal failure (RF) and the need for dialysis in the paediatric nephrology unit. Patients and methods: This was a retrospective and descriptive study in the pediatric nephrology unit from 1st January 2020 to 30 June 2021, including children with acute or chronic RF. The need for dialysis was judged to be met by its effectiveness in face of an indication. The data collected were analysed on sphinx plus 2017 software. Results: The prevalence of RF was 60% (n/N = 132/220). RF was acute in 59% (n/N = 78/132) of cases. The mean age was 6.53 ± 4.77 years with a sex ratio of 1.8. The mean serum creatinine level was 27.22 mg/L (240.9 μmol/L) and BUN at 0.85 g/L. The aetiologies were dominated by prerenal AKI (Acute Kidney Injury) complicating nephrotic syndrome (NS) in 37.2% (n/N = 29/78) and dehydration due to stomach flu in 17.6% (n/N = 9/51). Acute post-infectious glomerulonephritis including group A streptococcus and plasmodium falciparum accounted for 16.7% (n = 13/78) of intrinsic AKI. The need for dialysis was unmet in 50% (n/N = 7/14) with a mortality of 14.1% (n/N = 11/78). The mean age of the patients with chronic RF was 8.68 ± 4.74 years with a sex ratio of 2.6. The mean serum creatinine level was 36.56 mg/L (323.5 μmol/L) and the BUN level was 0.99 g/L. Half of the children were classified as having CKD stage II (early stage). The aetiologies were dominated by primary focal and segmental glomerulosclerosis (FSGS), 53.7% (n/N = 29/54), renal hypoplasia, 22.2% (n/N = 12/54) and reflux nephropathy, 29.4% (n/N = 5/17). The need for dialysis was unmet in 46.1% (n/N = 6/13). The overall mortality of chronic kidney disease (CKD) with RF was 29.6% (n/N = 8/27). Conclusion: The prevalence of RF was high i

关键词： Renal Failure Glomerulonephritis Hypodysplasia Dialysis Children

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Epidemiological, Clinical and Outcome Aspects of Care-Related Tetanus in Dakar, Senegal

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Advances in Infectious Diseases 2022年第2期12卷 230-240页

作者： Viviane Marie Pierre Cisse Ndèye Fatou Ngom Gueye Louise Fortes Imelda Mickelina Thoo Aminata Massaly Khardiata Diallo Mbaye Daye Ka Ndèye Aissatou Lakhe Assane Diouf Ndèye Maguette fall Daouda Thioub Aboubakry Sidikh Badiane Latyr Junior Diouf Alassane Sarr Sylvie Audrey Diop Cheikh Tidiane Ndour Masserigne Soumaré Moussa Seydi Infectious and Tropical Diseases Department Fann Teaching University Hospital Dakar Senegal Department of Community Health Alioune Diop University Bambey Senegal Department of Health Thies University Thies Senegal

Introduction: Tetanus portals of entry are numerous. Amongst these, the carerelated portals of entry are rarely reported. The aim of the study was to describe the epidemiological, clinical and outcome aspects and identify the factors associated with death from care-related tetanus. Patients and Methods: This is a retrospective study of descriptive and analytical purposes. Data were collected from the medical records of patients admitted to the Infectious and Tropical Diseases Department of the National University Hospital Center (CHNU) of Fann in Dakar for care-related tetanus during the period ranging from 1 January 2009 to 31 December 2016. Care-related tetanus was defined as any case of tetanus occurring after a surgical procedure, including circumcisions performed even outside a health facility. Results: In eight years, 50 cases of care-related tetanus were recorded. Care-related tetanus accounted for 6.7% of hospitalized tetanus cases. The mean age of patients was 21 ± 22 years, with a male predominance (sex ratio: 6.14). The procedure had been performed in most cases, either in a health facility in 22 patients (44%) or at home in 16 patients (32%), and occurred after circumcision. In 62% of cases the portal of entry was urological, followed by orthopedic surgery (14%) and visceral surgery (10%). The procedures performed were dominated by circumcision (31 cases), limb amputation (3 cases) and inguinal hernia repair (2 cases). Tetanus was immediately generalized on admission in all patients. Eighty-four percent (84%) of patients were admitted with Mollaret stage II. Cardiovascular (11 cases), infectious (10 cases) and respiratory (9 cases) complications were the most frequent. The hospital case fatality rate was 24%. Factors associated with death were female gender (p = 0.03), age between 15 - 60 years (p = 0.02), incubation time Conclusion: Care-related tetanus remains a concern in poor income countries, particularly in Senegal. The drop of these cases will req

关键词： Tetanus Care Surgery Dakar Senegal

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给生活来点“麻辣”灵感——对话线上家居店麻麻木创始人梁乐乐

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现代装饰（家居） 2016年第11期 56-63页

作者： mamamoon yuue Design WUU 见南花 Seletti Stuart Gardiner Tina Frey Designs Peca Ali Miller London Areaware New Works The Rise And fall Ligne Blanche Paris 范嘉苑

第一次看到＂麻麻木＂这个名字,很难让人联想到这是一家家居商店。为什么会取这么一个独特的名字呢？麻麻木的创始人梁乐乐解释道：＂是要刺激生活中的麻木感,把有意思的产品带给消费者＂。创立于2015年,并于2016年3月正式上线的麻麻木... 详细信息

第一次看到＂麻麻木＂这个名字,很难让人联想到这是一家家居商店。为什么会取这么一个独特的名字呢？麻麻木的创始人梁乐乐解释道：＂是要刺激生活中的麻木感,把有意思的产品带给消费者＂。创立于2015年,并于2016年3月正式上线的麻麻木是一家以＂鬼才设计＂为核心的线上家居商店,专注于创意家居领域,目前已与来自全球各地的不少优秀设计师取得联系,希望将有创意的＂鬼才设计＂家居产品呈现到大众面前。麻麻木的创始人梁乐乐毕业于伦敦中央圣马丁艺术与设计学院,在英国留学并工作了7年多,目前团队有10人左右,部分威员也是英国设计院校出身。

关键词：创始人家居生活梁对话灵感设计师设计学院

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Systemic Diseases in Dakar (Senegal): Spectrum, Epidemiological Aspect and Diagnostic Time-Limit

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Open Journal of Internal Medicine 2018年第3期8卷 196-206页

作者： B. S. Kane M. Niasse A. A. Ndiaye A. C. Ndao B. Djiba N. D. Diack B. C. fall M. A. Ndour M. Dieng D. Dia N. Diagne A. Faye A. Leye S. B. Gning S. Ndongo A. Pouye Department of Internal Medicine Le Dantec Hospital/Cheikh Anta DIOP University Dakar Senegal Department of Rheumatology Le Dantec Hospital/Cheikh Anta DIOP University Dakar Senegal Epidemiology Unit/University of Bambey Bambey Senegal Department of Internal Medicine Pikine Hospital/Cheikh Anta DIOP University Dakar Senegal Department of Internal Medicine Grand Yoff Hospital/Cheikh Anta DIOP University Dakar Senegal Department of Internal Medicine Principal Hospital Dakar Senegal

Introduction: Systemic diseases have been the subject of few studies in the African literature and have probably been under-estimated. The objective of our study was to specify their spectrum, their epidemiological aspects and diagnostic delay in Internal Medicine Departments of Dakar (Senegal). Material and Method: It was a multicentric retrospective and descriptive study regarding all systemic diseases during 119 months from 1st January 2005 to 30 November 2014 in 5 hospital centers down Dakar. Systemic diseases were retained according to their international consensus criteria. Results: During the studying period, 726 patients were included with 632 women and 94 men (sex ratio of 0.14). The average age was 43.76 years. Inflammatory rheumatoid family history was noted in 10.06% of cases. Rheumatoid arthritis (RA) was the predominant affection, recorded on 564 patients, isolated or associated with other systemic diseases. It was followed in a decreasing order, in the systemic auto-immune diseases sub-groupe, by systemic lupus (56 cases), Sj?gren’s syndrome (32 cases), Systemic Sclerosis (26 cases), Idiopathic inflammatory myopathies (21 cases), Undifferentiated connective tissue diseases (20 cases), Anti Phospholipid’s syndrome (6 cases) and Mixed connective tissue disease (6 cases). A diagnosis of systemic vasculitis was recorded in 19 patients. The other systemic affections were represented by systemic sarcoidosis (8 cases), Adult-onset Still’s disease (03 cases), amyloidosis (02 cases) and 02 cases of systemic syndrome associated to immunodeficiency. The mean diagnostic delay duration before the diagnostic was 3.46 years. Conclusion: Systemic diseases in internal medicine are characterized by their diversity, the clear predominance of RA, and significant diagnostic delay.

关键词： Connective Tissue Disease Rheumatoid Arthritis Systemic Vasculitis Sarcoidosis Adult-Onset Still’s Disease Africa South of the Sahara

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Case Study of Coastal Fog Events in Senegal Using LIDAR Ceilometer

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Journal of Atmospheric Science Research 2023年第4期6卷 64-76页

作者： Semou Ndao Cheikh Modou Noreyni fall Luis Duran Assie Regina Djiguene Diatta Abdou lahat Dieng Badara Sane Amadou Thierno Gaye Laboratory of Physics of the Atmosphere and Ocean-Siméon Fongang(LPAO-SF) Higher Polytechnic SchoolUniversity Cheikh Anta Diop(UCAD)PO BOX 5085DakarSenegal Department of Earth Physics and Astrophysics Complutense University of MadridMadrid28040Spain Meteorological Operation Service Representation of the Agency for the Safety of Air Navigation in Africa and Madagascar(ASECNA)in SenegalPO BOX 3144DakarSenegal Laboratory of Oceanography and Climate Experiments and Numerical Approaches(LOCEAN)Sorbonne University(SU)Paris75006France

This study aims to examine the atmospheric conditions characterising fog phenomena on the Senegalese coast focusing on two specific instances that occurred on April 3 and April 30,*** events were detected by the LIDAR Ceilometer installed at LPAOSF/ESP/UCAD and confirmed on the METARs of the meteorological stations at Dakar and Diass *** LIDAR’s backscatter signal showed that the fog of April 3 started around midnight with a vertical extension at 100 m altitude and dissipated around 10 *** April 30 event characterized by a good vertical extension from the surface up to 300 m above sea level,was triggered just after 2 *** lasted around 3 *** results showed that a decrease in temperature,accompanied by an increase in humidity and light wind,is favorable for the triggering and persistence of *** Level Pressure(SLP)anomaly fields show two distinct *** April 3 event was characterized by a zonal dipole of SLP anomalies between the Sahara and the northern Senegalese coast,while the April 30 event was characterized by a meridional dipole between the Sahara and the Gulf of Guinea area as far as the equatorial Atlantic.A weakening of the pressure around the study area was observed in both cases,allowing moisture advection to favor the onset of *** hovmoller diagrams of relative humidity and wind show that a good vertical extension of humidity associated with a westerly wind in the lower layers plays an important role in the formation and persistence of *** presence of dry air associated with a weak easterly wind in the middle layers could explain the low vertical extension of the fog on April 3.A strong wind in the lower layers would be responsible for the premature dissipation of the April 30 fog.

关键词： Coastal fog LIDAR Ceilometer Sea level pressure Relative humidity Temperature

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Neonatal Bilirubin Encephalopathy: Study of 30 Cases at Albert Royer National Children Hospital of Dakar

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Open Journal of Pediatrics 2020年第1期10卷 116-124页

作者： P. M. Faye Y. J. Dieng I. Deme D. F. Cissé M. Kane S. R. Tcheuffa Wekang A. Thiongane I. D. Ba A. Ba M. Gueye B. Niang P. S. Sow Amadou Sow Djibril Boiro N. R. Diagne-Gueye A. L. fall O. Ndiaye Centre Hospitalier National d’Enfants Albert Royer Dakar Senegal Centre Hospitalier Abass Ndao Dakar Senegal Hopital pour Enfants de Diamniadio Dakar Senegal

Introduction: Unconjugated bilirubin jaundice is a common symptom in neonatal period. In some babies, excessive serum bilirubin concentrations can place them at risk of acute bilirubin encephalopathy (BE) when the unconjugated pigment crosses the blood-brain barrier. Our study aimed to describe epidemiology, diagnosis and prognosis of BE at the Neonatology Department of Albert Royer Children’s Hospital of Dakar. Materials and Methods: It was a retrospective, descriptive study of cases of BE from January 1, 2015 to June 30, 2019. Obstetric and perinatal data as well as postnatal jaundice data (onset time, associated signs, signs of encephalopathy, treatment and evolution) were collected and analyzed by SPSS software version 2.0. Almost all newborns (27 cases;90%) were exclusively breastfed. At admission, all children exhibited blunt jaundice and signs of encephalopathy dominated by the abolition of archaic reflexes (76.7%), low suction (22 cases;73.3%), central apnea (12 cases, 40%). The mean serum bilirubinemia was 322 mg/litre. Neonatal infection (10 cases;33.3%) and fetal-maternal incompatibility (16 cases;53.3%) were the main causes. All children received intensive phototherapy and exsanguino transfusion was performed for 7 newborns (23.3%). Nine children died (30% mortality rate). Conclusion: Only better organisation of perinatal care with enhanced postnatal follow-up can reduce the incidence of EB.

关键词： Neonatal Hyperbilirubinemia Encephalopathy Perinatal Care

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小兴安岭阔叶红松林凋落物产量及动态的研究

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生态学杂志 1993年第6期12卷 29-33页

作者：刘传照李景文潘桂兰李传荣东北林业大学红松研究所

小兴安岭阔叶红松林凋落物产量及动态的研究刘传照，李景文，潘桂兰，李传荣（东北林业大学红松研究所，黑龙江带岭１５３１０６）ＬｉｔｔｅｒＰｒｏｄｕｃｔｉｏｎａｎｄＤｙｎａｍｉｃｓｉｎＢｒｏａｄｌｅａｖｃｄ－ＫｏｒｅａｎＰ... 详细信息

小兴安岭阔叶红松林凋落物产量及动态的研究刘传照，李景文，潘桂兰，李传荣（东北林业大学红松研究所，黑龙江带岭１５３１０６）ＬｉｔｔｅｒＰｒｏｄｕｃｔｉｏｎａｎｄＤｙｎａｍｉｃｓｉｎＢｒｏａｄｌｅａｖｃｄ－ＫｏｒｅａｎＰｉｎｅＦｏｒｅｓｔｓｉｎＸｉａｏｘｉｎｇａｎＭｏｕｎｔａｉｉｌｓ￥ＬｉｕＣｈｕａｎｚｈａｏ；ＬｉＪｉｎｇｗｅｎ；ＰａｎＧｕｉｌａｎ；ＬｉＣｈｕａｎｒｏｎｇ（ＩｎｓｔｉｔｕｔｅｏｆＫｏｒｅａｎＰｉｎｅＳｔｕｄｉｅｓ，ＮｏｒｔｂｅａｓｔＦｏｒｅｓｔｒｙＵｎｉｖｅｒｓｉｔｙ，Ｄａｉｌｉｎｇ，Ｈｅｉｌｏｎｇｊｉａｎｇ１５３１０６）．ＣｈｎｅｓｅＪｏｕｒｎａｌｏｆＥｃｏｌｏｇｙ，１９９３，１２（６）：２９－３３．Ｔｈｒｅｅ－ｙｅａｒｓｔｕｄｙｗａｓｄｏｎｅｏｎｌｉｔｔｅｒｐｒｏｄｕｃｔｉｏｎａｎｄｄｙｎａｍｉｃｓｕｎｄｅｒｂｒｏａｄｌｅａｖｅｄ－ＫｏｒｅａｎｐｉｎｅｆｏｒｅｓｔｓｉｎｔｈｅＸｉａｏｘｉｎｇａｎＭｏｕｎｔａｉｎｓ。Ｒｅｓｕｌｔｓｓｈｏｗｅｄｔｈａｔａｎｎｕａｌｌｉｔｔｅｒｆａｌｌｉｓ４．２５±０．１７ｔ．ｈａ￣（－１）．ｙｒ￣（－１）．Ａｍｏｎｇｔｏｔａｌｌｉｔｔｅｒｆａｌｌ。

关键词：阔叶红松林凋落物动态生态学

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珠海民营中小企业成长环境探究

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中共珠海市委党校珠海市行政学院学报 2019年第3期 71-78页

作者：中共珠海市委党校2018年秋季学期中青一班第二课题组殷旭东(指导) 周磊邓力平成军华冯影雪姜春红张庆祝颜昌威陈佛尧罗波徐臻中共珠海市委党校广东珠海519000 中共珠海市委党校

针对珠海城市能级量级不足问题,从珠海的民营中小企业生存成长环境入手,通过了解珠海民营中小企业的生长环境,找出目前政府政策中的疏漏,以及中小企业最关心和最需要解决的问题。通过实证分析珠海如何让中小企业进得来、留得下、活的欢... 详细信息

针对珠海城市能级量级不足问题,从珠海的民营中小企业生存成长环境入手,通过了解珠海民营中小企业的生长环境,找出目前政府政策中的疏漏,以及中小企业最关心和最需要解决的问题。通过实证分析珠海如何让中小企业进得来、留得下、活的欢、长得大,并提出符合珠海总体发展战略、产业政策的相应对策。

关键词：民营中小企业成长环境对策建议

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珠海复制推广横琴自贸区改革创新经验研究

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中共珠海市委党校珠海市行政学院学报 2019年第2期 57-66页

作者：中共珠海市委党校2018年秋季学期中青二班第二课题组焦佳节黄惠霞于海彬刘广兴周明灿杜国龙杨健林德宏张莹何宇浩蔡日山王玉勇桑艳军王鹏王越(指导) 苏朋(指导) 中共珠海市委党校广东珠海519000 不详中共珠海市委党校

我国自由贸易试验区的设立及其改革创新经验的复制推广,是以开放倒逼改革,探索建立一套与国际接轨的制度体系,促进全面对外开放新格局的形成。珠海横琴自贸区从2015年挂牌运行以来,在转变政府职能、优化政务环境、促进投资便利化和贸易... 详细信息

我国自由贸易试验区的设立及其改革创新经验的复制推广,是以开放倒逼改革,探索建立一套与国际接轨的制度体系,促进全面对外开放新格局的形成。珠海横琴自贸区从2015年挂牌运行以来,在转变政府职能、优化政务环境、促进投资便利化和贸易便利化等方面,积累了一系列改革创新经验。近几年来,珠海分三个批次在全市复制推广横琴自贸区经验,政务环境得到优化,通关便利化水平大幅度提升。与此同时,也遇到了市场主体不完善、个别改革创新事项与国家现行法律法规不一致、政府各部门协调联动机制不健全等问题。进一步在珠海复制推广横琴自贸区经验,需要加强宣传发动、慎重筛选复制推广事项、加快完善政府部门统筹协调联动机制和创新容错纠错机制。

关键词：横琴自贸区改革创新复制推广统筹协调联动机制

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