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Ferrite features in simulated transition zone of EH36 shipbuilding steel submerged arc welded by CaF_(2)-SiO_(2)-MnO fluxes

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Journal of Iron and Steel Research International 2024年第4期31卷 790-796页

作者： Ming Zhong Dong Hu Da-ming Guo Somnath basu Cong Wang Key Laboratory for Ecological Metallurgy of Multimetallic Mineral(Ministry of Education) Northeastern UniversityShenyang 110819LiaoningChina School of Metallurgy Northeastern UniversityShenyang 110819LiaoningChina The State Key Laboratory of Refractories and Metallurgy Wuhan University of Science and TechnologyWuhan 430081HubeiChina Department of Metallurgical Engineering and Materials Science Indian Institute of Technology BombayMumbai 400076MaharashtraIndia

Ferrite features in the simulated transition zone welded with CaF_(2)-SiO_(2)-MnO fluxes containing various MnO contents have been *** laser scanning microscopy has been applied to simulate the thermal cycling of the transition zone and the phase transformations during cooling have been in-situ *** has been found that the appearance temperature for ferrite side plate decreases with increasing Mn content in the weld metals caused by MnO content ***,growth rates for both ferrite side plate and acicular ferrite are significantly enhanced with a higher Mn content of weld ***,from the statistical fractions of salient microstructures,for all samples,the acicular ferrite,grain boundary ferrite,and polygonal ferrite take over more than 90%.It has also been demonstrated that with the increase in Mn content,the ferrite side plate fraction increases slightly from 5%to 10%and the acicular ferrite fraction shows a tendency of first increasing and then decreasing,which experiences the maximum with the flux containing 30 wt.%*** phenomenon is believed to be controlled by the O and Mn contents in weld metals synergistically.

关键词： Submerged arc welding Transition zone Phase transformation Microstructure

Optimal Bidding Strategies of Microgrid with Demand Side Management for Economic Emission Dispatch Incorporating Uncertainty and Outage of Renewable Energy Sources

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Energy Engineering 2024年第4期121卷 849-867页

作者： Mousumi basu Chitralekha Jena Baseem Khan Ahmed Ali Department of Power Engineering Jadavpur UniversityJadavpurIndia School of Electrical Engineering KIIT UniversityBhubaneswarIndia Department of Electrical and Computer Engineering Hawassa UniversityHawassaEthiopia Department of Electrical and Electronic Engineering Technology Faculty of Engineering and the Built EnvironmentUniversity of JohannesburgJohannesburgSouth Africa

In the restructured electricity market,microgrid(MG),with the incorporation of smart grid technologies,distributed energy resources(DERs),a pumped-storage-hydraulic(PSH)unit,and a demand response program(DRP),is a smarter and more reliable electricity *** consists of gas turbines and renewable energy sources such as photovoltaic systems and wind *** bidding strategies,prepared by MG operators,decrease the electricity cost and emissions from upstream grid and conventional and renewable energy sources(RES).But it is inefficient due to the very high sporadic characteristics of RES and the very high outage *** solve these issues,this study suggests non-dominated sorting genetic algorithm Ⅱ(NSGA-Ⅱ)for an optimal bidding strategy considering pumped hydroelectric energy storage and DRP based on outage conditions and uncertainties of renewable energy *** uncertainty related to solar and wind units is modeled using lognormal and Weibull probability ***-based DRP is used,especially considering the time of outages along with the time of peak loads and prices,to enhance the reliability of MG and reduce costs and emissions.

关键词： Micro-grid distributed energy resources demand response program uncertainty outage

Association between people’s attitudes towards human-elephant conflict and their locational,demographic,and socio-economic characteristics in Buxa Tiger Reserve and its adjoining area,India

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Regional Sustainability 2024年第1期5卷 11-25页

作者： Chiranjib NAD Tamal basu-ROY Department of Geography Raiganj UniversityRaiganj733134India

“Human-elephant conflict(HEC)”,the alarming issue,in present day context has attracted the attention of environmentalists and policy *** rising conflict between human beings and wild elephants is common in Buxa Tiger Reserve(BTR)and its adjoining area in West Bengal State,India,making the area ***’s attitudes towards elephant conservation activity are very crucial to get rid of HEC,because people’s proximity with wild elephants’habitat can trigger the occurrence of *** aim of this study is to conduct an in-depth investigation about the association of people’s attitudes towards HEC with their locational,demographic,and socio-economic characteristics in BTR and its adjoining area by using Pearson’s bivariate chi-square test and binary logistic regression *** is one of the constituent parts of Eastern Doors Elephant Reserve(EDER).We interviewed 500 respondents to understand their perceptions to HEC and investigated their locational,demographic,and socio-economic characteristics including location of village,gender,age,ethnicity,religion,caste,poverty level,education level,primary occupation,secondary occupation,household type,and source of *** results indicate that respondents who are living in enclave forest villages(EFVs),peripheral forest villages(PFVs),corridor village(CVs),or forest and corridor villages(FCVs),mainly males,at the age of 18–48 years old,engaged with agriculture occupation,and living in kancha and mixed houses,have more likelihood to witness ***,respondents who are illiterate or at primary education level are more likely to regard elephant as a main problematic animal around their villages and refuse to participate in elephant conservation *** the sake of a sustainable environment for both human beings and wildlife,people’s attitudes towards elephants must be friendly in a more prudent way,so that the two communities can live in harmony.

关键词： Human-elephant conflict Elephant conservation Chi-square test statistics Binary logistic regression Demographic and socioeconomic characteristics Buxa Tiger Reserve

Artificial intelligence strengthenes cervical cancer screening–present and future

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Cancer Biology & Medicine 2024年第10期 864-879页

作者： Tong Wu Eric Lucas Fanghui Zhao Partha basu Youlin Qiao School of Population Medicine and Public Health Chinese Academy of Medical Sciences and Peking Union Medical College Early Detection Prevention & Infections Branch International Agency for Research on Cancer (WHO) Department of Cancer Epidemiology National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital Chinese Academy of Medical Sciences and Peking Union Medical College

Cervical cancer is a severe threat to women's health. The majority of cervical cancer cases occur in developing countries. The WHO has proposed screening 70% of women with high-performance tests between 35 and 45 years of age by 2030 to accelerate the elimination of cervical cancer. Due to an inadequate health infrastructure and organized screening strategy, most low-and middleincome countries are still far from achieving this goal. As part of the efforts to increase performance of cervical cancer screening, it is necessary to investigate the most accurate, efficient, and effective methods and strategies. Artificial intelligence(AI) is rapidly expanding its application in cancer screening and diagnosis and deep learning algorithms have offered human-like interpretation capabilities on various medical images. AI will soon have a more significant role in improving the implementation of cervical cancer screening, management, and follow-up. This review aims to report the state of AI with respect to cervical cancer screening. We discuss the primary AI applications and development of AI technology for image recognition applied to detection of abnormal cytology and cervical neoplastic diseases, as well as the challenges that we anticipate in the future.

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Cracking the silent gallstone code:Wait or operate?

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World Journal of Clinical Cases 2024年第16期12卷 2692-2697页

作者： Aakansha Giri Goswami Somprakas basu Department of General Surgery All India Institute of Medical SciencesRishikesh 249203UttarakhandIndia

The widespread availability of abdominal ultrasound has revealed the common occurrence of asymptomatic *** the treatment for symptomatic gallstones is clear,the benefits of minimally invasive laparoscopic cholecystectomy have sparked debate about the best approach to managing silent *** potential for asymptomatic gallstones to become symptomatic or lead to complications complicates the decision-making process regarding surgical intervention,as it's uncertain when or which patients might develop ***,risk stratification appears to play a critical role in guiding decisions about silent ***,there is no definitive evidence to direct management,and a consensus-based on high-quality evidence is yet to be established.

关键词： Asymptomatic gallstones Silent gallstones Cholecystectomy Gallbladder cancer Risk stratification

Novel insights on oral squamous cell carcinoma management using long non-coding RNAs

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Oncology Research 2024年第10期32卷 1589-1612页

作者： SUBHAYAN SUR DIMPLE DAVRAY SOUMYA basu SUPRIYA KHEUR JAYANTA KUMAR PAL SHUCHI NAGAR AVINASH SANAP BHIMAPPA MRUDAGI SAMIR GUPTA Cancer and Translational Research Centre Dr.D.Y.Patil Biotechnology and Bioinformatics InstituteDr.D.Y.Patil VidyapeethTathawadePune411033India Bioinformatics Centre Dr.D.Y.Patil Biotechnology and Bioinformatics InstituteDr.D.Y.Patil VidyapeethPune411033India Department of Oral Pathology and Microbiology Dr.D.Y.Patil Dental College&HospitalDr.D.Y.Patil VidyapeethPune411018India Department of Surgical Oncology Dr.D.Y.Patil Medical CollegeHospital&Research CentreDr.D.Y.Patil VidyapeethPune411018India

Oral squamous cell carcinoma(OSCC)is one of the most prevalent forms of head and neck squamous cell carcinomas(HNSCC)with a poor overall survival rate(about 50%),particularly in cases of ***-based cancer biomarkers are a relatively advanced concept,and non-coding RNAs currently have shown promising roles in the detection and treatment of various *** review underlines the function of long non-coding RNAs(lncRNAs)in the OSCC and its subsequent clinical ***,a class of non-coding RNAs,are larger than 200 nucleotides and resemble mRNA in numerous ***,unlike mRNA,lncRNA regulates multiple druggable and non-druggable signaling molecules through simultaneous interaction with DNA,RNA,proteins,or microRNAs depending on concentration and localization in *** of oncogenic lncRNAs and downregulation of tumor suppressor lncRNAs are evident in OSCC tissues and body fluids such as blood and saliva indicating their potential as valuable *** inhibition of candidate oncogenic lncRNAs or overexpression of tumor suppressor lncRNAs showed potential therapeutic roles in in-vivo animal *** types of lncRNAs that are expressed differentially in OSCC tissue and bodily fluids have been systematically documented with specificity and *** review thoroughly discusses the biological functions of such lncRNAs in OSCC cell survival,proliferation,invasion,migration,metastasis,angiogenesis,metabolism,epigenetic modification,tumor immune microenvironment,and drug ***,we addressed the diagnostic and therapeutic importance of lncRNAs in OSCC pre-clinical and clinical systems,providing details on ongoing research and outlining potential future directions for advancements in this *** essence,this review could be a valuable resource by offering comprehensive and current insights into lncRNAs in OSCC for researchers in fundamental and clinical domains.

关键词： Oral squamous cell carcinoma(OSCC) Head and neck cancer Non-coding RNA Long non-coding RNA(lncRNA) Cancer diagnosis

Multitarget Thiol-Activated Tetrapyridyl Gold(Ⅲ)Complexes for Hypoxic Cancer Therapy

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CCS Chemistry 2024年第3期6卷 783-797页

作者： Xue-Quan Zhou Selda Abyar Imma Carbo-Bague Lan Wang Sebastian Türck Maxime ASiegler Uttara basu Ingo Ott Rongfang Liu Adriaan PIJzerman Sylvestre Bonnet Institute of Biopharmaceutical and Health Engineering Tsinghua Shenzhen International Graduate School(SIGS)Tsinghua UniversityShenzhen 518055 Leiden Institute of Chemistry Leiden University2333 CC Leiden Department of Chemistry Simon Fraser UniversityBurnabyBritish Columbia V5A 1S6 Institute of Medicinal and Pharmaceutical Chemistry Technische Universität Braunschweig38106 Braunschweig Department of Chemistry Johns Hopkins UniversityBaltimoreMaryland 21218 Division of Drug Discovery&Safety Leiden Academic Centre for Drug ResearchLeiden University2333 CC Leiden

Gold complexes have emerged as promising anticancer metallodrugs due to their efficient thioredoxin reductase(TrxR)inhibition,which disturbs the redox balance of cancer ***,in this model,the role of the ligand(s)coordinated to gold is often *** this work,we present a series of tetrapyridyl Au(Ⅲ)complexes that exhibit thiol-induced release of a Au(Ⅰ)ion and a tetrapyridyl *** formation of a free Au(Ⅰ)center is responsible for the expected TrxR ***,the released ligand,which was visible in cells due to its intense blue fluorescence,showed excellent binding properties to the hERG potassium ***,these ligands ended up in the lysosomes,resulting in significant lysosome ***,the Au(Ⅲ)complexes presented in this work showed broad-spectrum anticancer properties,both in hypoxic 2D monolayers and 3D tumor *** suggest that the interaction of the released Au(Ⅰ)center and the tetrapyridyl ligand with two different protein targets may combine into prodrugs that overcome hypoxia-induced drug deactivation.

关键词： anticancer Au(Ⅲ)complexes enzyme inhibtion potassium channel affinity lysosome damage cell imaging prodrug

Knowledge and prevention measures against dengue in southern Nepal

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Journal of Coastal Life Medicine 2014年第12期 998-1001页

作者： Biswas neupane Komal Raj Rijal Megha Raj Banjara basu dev Pandey Central Department of Microbiology Tribhuvan UniversityKirtipurNepal Everest International Clinic and Research Center KathmanduNepal

Objective:To ascertain the knowledge and prevention measures against dengue among selected adult population in southern ***:A cross sectional study was conducted in Rapti Zonal Hospital,Dang and Bharatpur Hospital,Chitwan during August-November,2011.A total of 212 patients were interviewed regarding their knowledge and practices about dengue *** samples were collected and investigated for the presence of anti-dengue IgM antibodies by ***:Data from 156 patients greater than 15 years were *** them,21 samples were found to possess anti-dengue IgM antibodies by ***,economically active people,farmers,unemployed and housewives were more frequently affected by *** the total,118(76%)were reported to know the disease ***,headache and myalgia were the most known symptoms and house drains and kitchen garden were known as the most common breeding sites of *** disposal,use of mosquito nets and covering water containers were the best known preventive ***:The overall knowledge of dengue was high,but females,old persons,unemployed and housewives had relatively little knowledge of ***,these groups may need special attention in future dengue education *** with knowledge of the disease more frequently reported the use of preventive measures,indicating the value of education programs as a tool in dengue prevention.

关键词： Dengue Knowledge Practices Prevention

Effect of Low Level Subchronic Microwave Radiation on Rat Brain

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Biomedical and Environmental Sciences 2016年第12期29卷 858-867页

作者： Pravin Suryakantrao Deshmukh Kanu Megha Namita Nasare basu dev Banerjee Rafat Sultana Ahmed Mahesh Pandurang Abegaonkar Ashok Kumar Tripathi Pramod Kumari Mediratta Environmental Biochemistry and Molecular Biology Laboratory Department of Biochemistry.University College of Medical Sciences & G.T.B.Hospital(University of Delhi) Department of Pharmacology University College of Medical Sciences & G.T.B.Hospital(University of Delhi) Centre for Applied Research in Electronics(CARE) Indian Institute of Technology

Objective The present study was designed to investigate the effects of subchronic low level microwave radiation （MWR） on cognitive function, heat shock protein 70 （HSP70） level and DNA damage in brain of Fischer rats. Methods Experiments were performed on male Fischer rats exposed to microwave radiation for 90 days at three different frequencies： 900, 2800, and 2450 MHz. Animals were divided into 4 groups： Group I： Sham exposed, Group I1： animals exposed to microwave radiation at 900 MHz and specific absorption rate （SAR） 5.953 x 10-4 W/kg, Group II1： animals exposed to 1800 MHz at SAR 5.835 x 20-4 W/kg and Group IV： animals exposed to 2450 MHz at SAR 6.672 x 10-4 W/kg. All the animals were tested for cognitive function using elevated plus maze and Morris water maze at the end of the exposure period and subsequently sacrificed to collect brain tissues. HSP70 levels were estimated by ELISA and DNA damage was assessed using alkaline comet assay. Results Microwave exposure at 900-2450 MHz with SAR values as mentioned above lead to decline in cognitive function, increase in HSP70 level and DNA damage in brain. Conclusion The results of the present study suggest that low level microwave exposure at frequencies 900, 2800, and 2450 MHz may lead to hazardous effects on brain.

关键词： Brain Cognitive function Comet assay DNA damage HSP70 Microwave radiation