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Hepatic and gastrointestinal disturbances in Egyptian patients infected with coronavirus disease 2019: A multicentre cohort study

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World Journal of Gastroenterology 2021年第40期27卷 6951-6966页

作者： Hend Ibrahim Shousha Shimaa Afify Rabab Maher Noha Asem Eman Fouad Ehab F Mostafa Mohammed A Medhat Amr Abdalazeem Hazem Elmorsy Miriam M Aziz Rateba S Mohammed Mohamed Ibrahem Hassan Elgarem Dalia Omran Mohamed Hassany bassem elsayed Ahmed Y Abdelaziz Mohamed El Kassas Endemic Medicine Faculty of MedicineCairo UniversityCairo 11562Egypt Gastroenterology Department National Hepatology&Tropical Medicine Research InstituteCairo 11563Egypt Hepatology Department Students HospitalCairo UniversityGiza 12566Egypt The Public Health Department Faculty of MedicineCairo UniversityCairo 11562Egypt Egyptian Ministry of Health and PopulationCairo 11567Egypt Department of Tropical Medicine and Gastroenterology Faculty of MedicineAssiut UniversityAssiut 15655Egypt Endemic Medicine Department Faculty of MedicineHelwan UniversityCairo 13544Egypt Internal Medicine 15 Mayo Smart HospitalMinistry of Health and PopulationCairo 13488Egypt Pediatrics Department Faculty of MedicineCairo UniversityCairo 11562Egypt Occupational and Environmental Medicine Department Faculty of MedicineCairo UniversityCairo 11562Egypt Clinical Biochemistry Department Faculty of medicineCairo UniversityCairo 11562Egypt Endemic Medicine Department Faculty of MedicineCairo UniversityCairo 11562Egypt Urology Department Cairo UniversityCairo 11562Egypt

BACKGROUND Various liver and gastrointestinal involvements occur in patients with coronavirus disease 2019(COVID-19)at variable *** studies report mild liver function disturbances correlated with COVID-19 severity,though liver failure is *** To study liver and gastrointestinal dysfunctions in Egyptian patients with COVID-19 and their relation to disease outcomes METHODS This multicentre cohort study was conducted on 547 Egyptian patients from April 15,2020 to July 29,*** polymerase chain reaction-confirmed COVID-19 cases were included from four quarantine hospitals affiliated to the Egyptian ministry of *** information,laboratory characteristics,treatments,fibrosis-4(FIB-4)index,COVID-19 severity,and outcomes were recorded and compared according to the degree of liver enzyme elevation and the presence of gastrointestinal ***-ups were conducted until discharge or *** analyses were performed to determine the independent factors affecting *** This study included 547 patients,of whom 53(9.68%)died during hospitalization and 1 was discharged upon his ***’mean age was 45.04±17.61 years,and 21.98%had severe or critical *** aminotransferase(ALT)and aspartate aminotransferase(AST)were available for 430 and 428 patients,*** total,26%and 32%of patients had elevated ALT and AST,*** liver injury with ALT or AST elevation exceeding 3-fold was recorded in 21(4.91%)and 16(3.73%)patients,*** gender,smoking,hypertension,chronic hepatitis C,and lung involvement were associated with elevated AST or *** was elevated in 50%of patients over ***-4 was significantly higher in patients admitted to the intensive care unit(ICU),those with more severe COVID-19,and *** independent variables affecting outcome were supplementary vitamin C intake(1 g daily capsules)[odds ratio(OR):0.05,95%confidence interval(CI

关键词： COVID-19 Egypt Liver injury Gastrointestinal symptoms Fibrosis-4 Liver enzymes

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Dynamics of a Rational Difference Equation

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Chinese Annals of Mathematics,Series B 2009年第2期30卷 187-198页

作者： Elmetwally M. ELABBASY elsayed M. elsayed Department of Mathematics Faculty of Science Mansoura University

The authors investigate the global behavior of the solutions of the difference equation xn＋1=axn-1xn-k/bxn-p＋cxn-q,n=0,1,…where the initial conditions x-r, x-r＋1, x-r＋2,… , x0 are arbitrary positive real numbers, r = max{l, k,p, q） is a nonnegative integer and a, b, c are positive constants. Some special cases of this equation are also studied in this paper.

关键词： Stability Periodic solutions Difference equations

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Interplay between strong Allee effect, harvesting and hydra effect of a single population discrete-time system

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International Journal of Biomathematics 2016年第1期9卷 65-89页

作者： Debaldev Jana elsayed M. elsayed Ecological Modelling LaboratoryDepartment of Zoology Visva-Bharati University Santiniketan 731235 India Mathematics DepartmentFaculty of Science King Abdulaziz UniversityP. O. Box 80203 Jeddah 21589 Saudi Arabia Department of MathematicsFaculty of Science Mansoura University Mansoura 35516 Egypt

The dynamics of a single population with non-overlapping generations can be described deterministically by a scalar difference equation in this study. A discrete-time Beverton- Holt stock recruitment model with Allee effect, harvesting and hydra effect is proposed and studied. Model with strong Allee effect results from incorporating mate limitation in the Beverton-Holt model. We show that these simple models exhibit some interesting （and sometimes unexpected） phenomena such as the hydra effect, sudden collapses and essential extinction. Along with this, harvesting is a socio-economie issue to continue any system generation after generation. Different dynamical behaviors for these situations have been illustrated numerically also. The biological implications of our analytical and numerical findings are discussed critically.

关键词： Beverton-Holt model hydra effect harvesting Allee effect.

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Variation in metabolic enzymatic activity in white muscle and liver of blue tilapia,Oreochromis aureus,in response to long-term thermal acclimatization

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Chinese Journal of Oceanology and Limnology 2015年第3期33卷 696-704页

作者： elsayed M.YOUNIS Zoology Department College of Science King Saud University

The effects of rearing temperature on white muscle and hepatic phosphofructokinase （PFK）, pyruvate kinase （PK）, lactate dehydrogenase （LDH）, aspartate aminotransferase （AST） and alanine aminotransferase （ALT） were examined in fingerlings of blue tilapia, Oreochromis aureus. The experiment was conducted for 14 weeks at temperatures of 18, 22, 26, 30, and 34℃. The activity of the glycolytic enzymes PFK, PK, and LDH in white muscle increased significantly with increase in water temperature. A reverse trend was observed for these enzymes in the liver, except for LDH, which behaved in the same manner as in white muscle. Cytosolic AST and ALT activity increased in both white muscle and liver in response to warm thermal acclimatization, while a reduction in mitochondrial AST and ALT activity was noticed at high temperatures in comparison with those at a lower temperature.

关键词： Nile tilapia thermal acclimatization metabolism enzymes

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Deep Reinforcement Learning-Based Job Shop Scheduling of Smart Manufacturing

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Computers, Materials & Continua 2022年第12期73卷 5103-5120页

作者： Eman K.elsayed Asmaa K.elsayed Kamal A.Eldahshan School of Computers Science Canadian International College(CIC).Department of MathematicsFaculty of Science(Girls)AL-Azhar UniversityCairo11511Egypt Department of Mathematics Faculty of Science(Girls)AL-Azhar UniversityCairo11511Egypt Department of Mathematics Faculty of ScienceAL-Azhar UniversityCairo11511Egypt

Industry 4.0 production environments and smart manufacturing systems integrate both the physical and decision-making aspects of manufacturing operations into autonomous and decentralized *** of the key aspects of these systems is a production planning,specifically,Scheduling operations on the *** cope with this problem,this paper proposed a Deep Reinforcement Learning with an Actor-Critic algorithm(DRLAC).We model the Job-Shop Scheduling Problem(JSSP)as a Markov Decision Process(MDP),represent the state of a JSSP as simple Graph Isomorphism Networks(GIN)to extract nodes features during scheduling,and derive the policy of optimal scheduling which guides the included node features to the best next action of *** addition,we adopt the Actor-Critic(AC)network’s training algorithm-based reinforcement learning for achieving the optimal policy of the *** prove the proposed model’s effectiveness,first,we will present a case study that illustrated a conflict between two job scheduling,secondly,we will apply the proposed model to a known benchmark dataset and compare the results with the traditional scheduling methods and trending *** numerical results indicate that the proposed model can be adaptive with real-time production scheduling,where the average percentage deviation(APD)of our model achieved values between 0.009 and 0.21 comparedwith heuristic methods and values between 0.014 and 0.18 compared with other trending approaches.

关键词： Reinforcement learning job shop scheduling graphical isomorphism network actor-critic networks

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Experimental flexural behavior of SMA-FRP reinforced concrete beam

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Frontiers of Structural and Civil Engineering 2013年第4期7卷 341-355页

作者： Adeel ZAFAR bassem ANDRAWES Department of Civil Engineering University of Illinois at Urbana-ChampaignIllinois 61820USA

The most critical drawback in currently used steel reinforcement in reinforced concrete(RC)structures is susceptibility to accumulation of plastic deformation under excessive *** concrete structures due to damaged(yielded)steel reinforcement have undergone costly repairs and *** research presents a new type of shape memory alloy(SMA)-based composite reinforcement with ability to withstand high elongation while exhibiting pseudoelastic *** this study,small diameter SMA wires are embedded in thermoset resin matrix with or without additional glass fibers to develop composite *** technique of new proposed composite is validated using microscopy *** proposed SMA-FRP composite square rebars are first fabricated and then embedded in small scale concrete T-beam.3-point bending test is conducted on manufactured RC beam using a cyclic displacement controlled regime until *** is found that the SMA-FRP composite reinforcement is able to enhance the performance of concrete member by providing re-centering and crack closing capability.

关键词： re-centering shape memory alloys concrete composite fiber reinforced polymer scanning electron microscopy

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Practical stabilization of a class of uncertain time-varying nonlinear delay systems

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控制理论与应用（英文版） 2009年第2期7卷 175-180页

作者： bassem Ben HAMED Mohamed Ali HAMMAMI Institut Supérieur des Sciences Appliquées et de Technologie de Gabès Département de MathématiquesRue Amor Ben El Khatab 6029 GabèsTunisia Faculté des Sciences de Sfax Département de Mathématiques BP 802 Route Soukra km 4 Sfax 3018Tunisia

In this paper we deal with a class of uncertain time-varying nonlinear systems with a state delay. Under some assumptions, we construct some stabilizing continuous feedback, i.e. linear and nonlinear in the state, which can guarantee global uniform exponential stability and global uniform practical convergence of the considered system. The quadratic Lyapunov function for the nominal stable system is used as a Lyapunov candidate function for the global system. The results developed in this note are applicable to a class of dynamical systems with uncertain time-delay. Our result is illustrated by a numerical example.

关键词： Nonlinear system Time-delay Feedbacks Practical convergence Lyapunov function

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Neglected traumatic hip dislocation: Influence of the increased intracapsular pressure

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World Journal of Orthopedics 2018年第3期9卷 35-40页

作者： elsayed Ibraheem elsayed Massoud Department of Orthopaedic Sohag Teaching Hospital General Organization for Teaching Hospitals and Institutes

AIM To investigate that the increased intracapsular pressure, during the delay period, can interrupt the blood flow to the femoral *** An observational retrospective study included a group of 17 patients with traumatic hip dislocation, their ages at time of injury averaged 26(range from 3 to 70) years. Outcomes were assessed clinically and radiographically at a period averaged 11.5(range from 4 to 20) *** Minor trauma caused dislocation in seven and severe trauma in ten patients. All dislocations were posterior, six isolated dislocation and 11 were associated with other injuries. The negligence period averaged 2.5(ranged from 1 to 4) d. At the latest visit, the radiography revealed normal hip in 11 and avascular necrosis(AVN) in six patients. Clinically, eight patients were rated as excellent, three good, three fair and three *** We believe the factors that contribute to increased intracapsular pressure also increase the influence of delayed reduction toward the development of AVN.

关键词： Avascular necrosis Intracapsular pressure Traumatic hip dislocation Delayed reduction

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Evaluation of hypolipidemic Marrubium vulgare effect in Triton WR-1339-induced hyperlipidemia in mice

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Asian Pacific Journal of Tropical Medicine 2016年第5期9卷 439-445页

作者： Abeer Y Ibrahim Saber F Hendawy Ahmed A A elsayed elsayed A Omer Medicinal and Aromatic Plants Researches Dept. Pharmaceutical and Drug Industries Division National Research Centre

Objective: To evaluate the hypocholesterolemic and hypotriglyceridemic activities of four Marrbium vulgare(M. vulgare) herb extracts using Triton WR-1339-induced hyperlipidemia in mice. Methods: Hyperlipidemia was developed by intraperitoneal injection of Triton(200 mg/kg body weight). The animals were divided into main four groups of eight mice each: normal control group, hyperlipidemic control group, hyperlipidemic plus tween-40 control and treated group. The fourth one was divided into four subgroups, petroleum ether extract group, chloroform extract group, ethyl acetate extract group and methanol extract treated group each of them contains two sub-sub group for treating animals with two doses at 0.1 and 0.25 LD50. Results: After 7 h and 24 h of treatment, the intragastric administration of all extracts caused a significant decrease of plasma total cholesterol. Triglyceride levels were also significantly lowered by all extracts while petroleum ether produced the lowest decreasing level. Similar results were observed for LDL-cholesterol concentrations. Furthermore, more polar extracts(methanol and ethyl acetate)-soluble fractions showed a significant ameliorative action on elevated atherogenic index(AI) and LDL/HDL-C ratios, while these atherogenic markers were not statistically suppressed by the chloroform and petroleum ether-soluble extract. Conclusion: The findings indicated that Marrubium may contain polar products able to lower plasma lipid concentrations and might be beneficial in treatment of hyperlipidemia and atherosclerosis.

关键词： Anti-hyperlipidemia Marrubium vulgare Triton Antioxidant Atherogenic index

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Healing of subcutaneous tendons: Influence of the mechanical environment at the suture line on the healing process

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World Journal of Orthopedics 2013年第4期4卷 229-240页

作者： elsayed Ibraheem elsayed Massoud Orthopaedic Department Sohag Teaching Hospital General Organization for Teaching Hospitals and Institutes 82521 Tahta Sohag Egypt

Tendon ruptures remain a significant musculoskeletal injury. Despite advances in surgical techniques and procedures, traditional repair techniques maintain a high incidence of rerupture or tendon elongation. Mechanical loading and biochemical signaling both control tissue healing. This has led some researchers to consider using a technique based on tension regulation at the suture line for obtaining good healing. However, it is unknown how they interact and to what extent mechanics control biochemistry. This review will open the way for understanding the interplay between mechanical loading and the process of tendon healing.

关键词： Tendon Healing Mechanical loading Mechanotransduction Rupture Repair

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