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Current controversies and advances in the management of pancreatic adenocarcinoma

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World Journal of Gastrointestinal Oncology 2021年第6期13卷 472-494页

作者： Muhammad Shehroz zeeshan zeeshan Ramzan Gastrointestinal Section Department of MedicineTexas Health Harris Methodist HospitalFort WorthTX 76104United States

Pancreatic adenocarcinoma is a lethal disease with a mortality rate that has not significantly improved over *** is likely due to several challenges unique to pancreatic *** patients with pancreatic cancer are diagnosed at a late stage of disease due to the lack of specific symptoms prompting an early investigation.A small subset of patients who are diagnosed at an early stage have a better chance at survival with curative surgical resection,but most patients still succumb to the disease in a few *** dismal overall prognosis is due to suspected micro-metastasis at an early *** to this reason,there is a recent interest in treating all patients with pancreatic cancers with systemic therapy upfront(including the ones that are surgically resectable).This approach is still not the standard of care due to the lack of robust prospective data *** advancements in treatment regimens of chemotherapy,radiation and immunotherapy have improved the overall short-term survival but the long-term survival still remains *** approaches in diagnosis and treatment have shown promise in clinical studies but long-term clinical data is *** following manuscript presents an overview of the epidemiology,diagnosis,staging,recent advances,novel approaches and controversies in the management of pancreatic adenocarcinoma.

关键词： Pancreatic adenocarcinoma Advances in management Imaging Novel approaches Chemotherapy Controversies

First-Principles Investigation of Charge Transfer Mechanism of B-Doped 3C-SiC Semiconductor Material

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World Journal of Condensed Matter Physics 2024年第2期14卷 35-44页

作者： Abdullahi Alkali Dauda Muhammad Yusuf Onimisi Adeyemi Joshua Owolabi Hameed Adeneyi Lawal Hassan Muhammad Gambo bashir Mohammed Aliyu Surajo Bala Muhammad Lamido Madugu Muhammad Abdurrahman Nainna Johnson Akinade Bamikole Physics Department Faculty of Science Air Force Institute of Technology Kaduna Nigeria Physics Department Faculty of Science Nigeria Defence Academy Kaduna Nigeria Physics Department Umaru Musa Yar&#8217adua University Batagarawa Nigeria Physics Department Faculty of Science Gombe State University Gombe Nigeria Physics Department Federal University of Lafia Lafia Nigeria

This study delves into the charge transfer mechanism of boron (B)-doped 3C-SiC through first-principles investigations. We explore the effects of B doping on the electronic properties of 3C-SiC, focusing on a 12.5% impurity concentration. Our comprehensive analysis encompasses structural properties, electronic band structures, and charge density distributions. The optimized lattice constant and band gap energy of 3C-SiC were found to be 4.373 Å and 1.36 eV respectively, which is in agreement with previous research (Bui, 2012;Muchiri et al., 2018). Our results show that B doping narrows the band gap, enhances electrical conductivity, and influences charge transfer interactions. The charge density analysis reveals substantial interactions between B dopants and surrounding carbon atoms. This work not only enhances our understanding of the material’s electronic properties, but also highlights the importance of charge density analysis for characterizing charge transfer mechanisms and their implications in the 3C-SiC semiconductors.

关键词： First-Principles Calculations DFT Boron (B)-Doped 3C-SiC Charge Transfer

Complex neutrosophic generalised dice similarity measures and their application to decision making

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CAAI Transactions on Intelligence Technology 2020年第2期5卷 78-87页

作者： zeeshan Ali Tahir Mahmood Department of Mathematics and Statistics International Islamic UniversityIslamabadPakistan

Complex neutrosophic set(CNS)is a modified version of the complex fuzzy set,to cope with complicated and inconsistent information in the environment of fuzzy set *** CNS is characterised by three functions expressing the degree of complex-valued membership,complex-valued abstinence and degree of complex-valued *** aim of this manuscript is to initiate the novel dice similarity measures and generalised dice similarity using *** special cases of the investigated measures are discussed with the help of some ***,some distance measures based on CNS are also proposed in this ***,the authors applied the generalised dice similarity measures and weighted generalised dice similarity measures using CNS to the pattern recognition model to examine the reliability and superiority of the established *** advantages and comparative analysis of the proposed measures with existing measures are also discussed in *** last,a numerical example is provided to illustrate the validity and applicability of the presented measures.

关键词： theory. similarity valued

碳水化合物酶对家禽生长性能和肠道健康的影响(续1)

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国外畜牧学（猪与禽） 2024年第3期44卷 115-119页

作者：王晶晶(译) 王丽萍(译) 夏俊花(审) Ahmad Raza Saira bashir Romana Tabassum 不详

家禽可提供优质的蛋白质和微量营养物质。在家禽生产中,饲料是主要的投入品,其成本占总生产成本的70%~75%。家禽的饲料主要由谷物组成,能为家禽提供所需的能量。然而,这些谷物含有不同水平的抗营养因子,如非淀粉多糖。由于家禽自身缺乏... 详细信息

家禽可提供优质的蛋白质和微量营养物质。在家禽生产中,饲料是主要的投入品,其成本占总生产成本的70%~75%。家禽的饲料主要由谷物组成,能为家禽提供所需的能量。然而,这些谷物含有不同水平的抗营养因子,如非淀粉多糖。由于家禽自身缺乏重要的内源性酶(碳水化合物酶),无法消化这些非淀粉多糖,从而会增加肠道食糜的黏度,影响营养物质的运输和吸收。这些非淀粉多糖还通过引起肠道微生物群对可消化营养物质的竞争增加家禽感染有害微生物的机会。这不仅会影响家禽的健康,还会增加生产成本。因此,找到效率高和起作用的解决方法极为重要。在非淀粉多糖含量高的日粮中添加碳水化合物酶是解决方案之一,对家禽生产具有重要的影响。多年来,饲用酶一直被用于提高动物消化率和生产性能,但对某些饲料原料的活性有限。新一代碳水化合物酶具有广泛的活性和稳定性,有助于降解日粮中复杂的底物,提高家禽的生产性能。本综述总结了使用碳水化合物酶改善家禽生产性能和肠道健康的最新研究成果。

关键词：营养学兽医学生理学微生物学结构生物学生物技术

Graphite versus graphene:plasmonic nanopore DNA sequencing

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Optoelectronics Letters 2023年第6期19卷 353-358页

作者： bashir Fotouhi Faculty of Electrical and Computer Engineering University of KurdistanKurdistanIran

The plasmonic-based graphite-and graphene-nanopores have been investigated by employing the hybrid quantum/classical scheme(HQCS).Transverse,longitudinal,and total absorption spectra obtained from HQCS are analyzed for the graphite and graphene *** were examined for each structure in the presence of deoxyribonucleic acid(DNA) *** simple excitation of the total mode in graphene nanopore shows the best selectivity for DNA sequencing.A novel method based on the transverse and longitudinal modes in a time-series approach has been proposed for selectivity *** the proposed time-series method,the outstanding results show that graphite nanopore is more sensitive than and as selective as graphene *** paper suggests that time-step analysis of the plasmonic absorption in the graphite nanopore is a promising method for DNA sequencing.

关键词： graphene method absorption

Investigation of ZrO2 nanoparticles concentration and processing time effect on the localized PEO coatings formed on AZ91 alloy

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Journal of Magnesium and Alloys 2019年第4期7卷 555-565页

作者： zeeshan Ur Rehman Dongjin Choi School of Materials Science and Engineering Hongik UniversitySejongRepublic of Korea

AZ91 Mg alloy was treated through a new localized PEO(Plasma Electrolytic Oxidation)coating approach,using electrolyte solutions with varying ZrO2 nanoparticles concentration(2-8 g/L)and processing *** increase in the ZrO2 concentration,several microstructural changes were observed including;formation of cluster-type structure,damage to the inner layers(∼30 min)and sealing of *** analysis of the final coatings was carried out using potentiodynamic polarization,electrochemical impedance spectroscopy and post-corrosion *** was explored that highest corrosion resistance(Rp∼81.17 kΩcm^2)of the coatings was obtained for ZrO2∼2 g/***,higher concentration of the ZrO2 nanoparticles caused weak crystalline coating structure,due to unstable and lower intensity discharges,thus failed to offer high corrosion resistance performance.

关键词： Magnesium alloy PEO coating ZrO2 Corrosion Nanoparticles addition

碳水化合物酶对家禽生长性能和肠道健康的影响

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国外畜牧学（猪与禽） 2024年第2期44卷 110-112页

作者：王晶晶(译) 王丽萍(译) 夏俊花(审) Ahmad Raza Saira bashir Romana Tabassum 不详

家禽可提供优质的蛋白质和微量营养物质。在家禽生产中,饲料是主要的投入品,其成本占总生产成本的70%~75%。家禽的饲料主要由谷物组成,能为家禽提供所需的能量。然而,这些谷物含有不同水平的抗营养因子,如非淀粉多糖。由于家禽自身缺乏重要的内源性酶(碳水化合物酶),无法消化这些非淀粉多糖,从而会增加肠道食糜的黏度,影响营养物质的运输和吸收。这些非淀粉多糖还可通过引起肠道微生物群对可消化营养物质的竞争增加家禽感染有害微生物的机会。这不仅会影响家禽的健康,还会增加生产成本。因此,找到效率高和起作用的解决方法极为重要。在非淀粉多糖含量高的日粮中添加碳水化合物酶是解决方案之一,对家禽生产具有重要的作用。多年来,饲用酶一直被用于提高动物消化率和生产性能,但对某些饲料原料的活性有限。新一代碳水化合物酶具有广泛的活性和稳定性,有助于降解日粮中复杂的底物,提高家禽的生产性能。本综述总结了使用碳水化合物酶改善家禽生产性能和肠道健康的最新研究成果。

关键词：营养学兽医学生理学微生物学结构生物学生物技术

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Designing and Evaluating a Collaborative Knowledge Management Framework for Leaf Disease Detection

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Computer Systems Science & Engineering 2022年第8期42卷 751-777页

作者： Komal bashir Mariam Rehman Afnan bashir Faria Kanwal Department of Computer Science Lahore College for Women UniversityLahore54000Pakistan Department of Information Technology Government CollegeFaisalabad54000Pakistan Engage Research Lab School of Law and SocietyUniversity of the Sunshine CoastSippy DownsQLD 4556Australia

Knowledge Management(KM)has become a dynamic concept for inquiry in *** management of knowledge from multiple sources requires a systematic approach that can facilitate capturing all important aspects related to a particular discipline,several KM frameworks have been designed to serve this *** research aims to propose a Collaborative Knowledge Management(CKM)Framework that bridges gaps and overcomes weaknesses in existing *** paper also validates the framework by evaluating its effectiveness for the agriculture sector of Pakistan.A software LCWU aKMS was developed which serves as a practical implementation of the concepts behind the proposed CKMF *** aKMS served as an effective system for rice leaf disease detection and *** aimed to enhance CKM through knowledge sharing,lessons learned,feedback on problem resolutions,help from co-workers,collaboration,and helping *** were collected from 300 rice crop farmers by questionnaires based on *** Olfman model was used to estimate the effectiveness of *** tests were performed including frequency measures of variables,Cronbach’s alpha reliability,and Pearson’s *** research provided a KMS depicting KM and collaborative *** disease detection module was evaluated using the precision and recall method and found to be 94.16%*** system could replace the work of extension agents,making it a cost and time-effective initiative for farmer betterment.

关键词： Collaborative knowledge management framework jennex olfman km success model knowledge management rice disease detection

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纺梭负蝗过冷却能力和低温存活率研究

北方农业学报 2024年第3期52卷 108-113页

作者：李文博 HAIDER bashir NAWAZ 王自杰唐佳威杨爽陈欢欢田睿林曲靖师范学院生物资源与食品工程学院云南曲靖655011 黑龙江省农业科学院佳木斯分院黑龙江佳木斯154007 谱尼测试集团股份有限公司吉林长春130103 内蒙古师范大学生命科学与技术学院内蒙古呼和浩特010022

【目的】明确纺梭负蝗(Atractomorpha burri)种群的耐寒能力。【方法】利用过冷却点测定仪分别测定云南省曲靖市纺梭负蝗各虫态过冷却能力和低温条件下低龄和老龄若虫的存活率。【结果】不同虫态纺梭负蝗的过冷却点和结冰点差异显著(P<0... 详细信息

【目的】明确纺梭负蝗(Atractomorpha burri)种群的耐寒能力。【方法】利用过冷却点测定仪分别测定云南省曲靖市纺梭负蝗各虫态过冷却能力和低温条件下低龄和老龄若虫的存活率。【结果】不同虫态纺梭负蝗的过冷却点和结冰点差异显著(P<0.05),卵期过冷却点和结冰点最低,分别为-16.16、-8.13℃;3龄若虫的过冷却点和结冰点最高,分别为-8.35、-5.20℃。雄性成虫的过冷却点和结冰点分别为-10.26、-7.18℃,低于雌性成虫的-9.00、-7.00℃。过冷却点和结冰点在同一虫态不同个体中的变异符合正态分布。3龄若虫和5龄若虫在低温条件下达到50%以上死亡率的温度分别为-7.00、-9.00℃。【结论】纺梭负蝗卵期的耐寒性最强,5龄若虫具有更强的低温耐受性,雄性成虫抗寒能力强于雌性成虫。

关键词：纺梭负蝗过冷却能力低温存活率