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Survival and outcomes for co-infection of chronic hepatitis C with and without cirrhosis and COVID-19: A multicenter retrospective study

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World Journal of Gastroenterology 2021年第42期27卷 7362-7375页

作者： Shimaa Afify basem eysa Fatma Abdel Hamid Omnia M Abo-elazm Mohamed A edris Rabab Maher Ahmed Abdelhalim Muhammad Mostafa Abdel Ghaffar Dalia A Omran Hend Ibrahim Shousha Department of Gastroenterology National Hepatology and Tropical Medicine Research InstituteCairo 20222Egypt Department of endemic Medicine Faculty of MedicineFayoum UniversityEl-Fayoum 13524Egypt Department of Biostatistics and Cancer epidemiology National Cancer InstituteCairo 20222Egypt Department of Gastroenterology Students HospitalCairo UniversityGiza 12111Egypt The General Organization for Teaching Hospitals and Institutes Cairo 11562Egypt Department of endemic Medicine Faculty of MedicineCairo UniversityCairo 11562Egypt

BACKGROUND Chronic liver disease,particularly cirrhosis,is associated with worse outcomes in patients infected with coronavirus disease 2019(COVID-19).AIM To assess outcomes of COVID-19 infection among patients with pre-existing hepatitis C with or without liver *** This multicenter,retrospective cohort study included all cases of confirmed coinfection of severe acute respiratory syndrome coronavirus 2 and chronic hepatitis C with or without liver cirrhosis who were admitted to six hospitals(Al-Sahel Hospital,Al-Matareya Hospital,Al-Ahrar Hospital,Ahmed Maher Teaching Hospital,Al-Gomhoreya Hospital,and the National Hepatology and Tropical Medicine Research Institute)affiliated with the General Organization for Teaching Hospitals and Institutes in *** were recruited from May 1,2020,to July 31,***,laboratory,imaging features,and outcomes were *** regression analysis was performed to detect factors affecting *** This retrospective cohort study included 125 patients with chronic hepatitis C and COVID-19 co-infection,of which 64(51.20%)had liver cirrhosis and 40(32.00%)***,cough,dyspnea,and fatigue were the most frequent symptoms in patients with liver ***,sore throat,fatigue,myalgia,and diarrhea were significantly more common in patients with liver cirrhosis than in noncirrhotic *** was no difference between patients with and without cirrhosis regarding *** patients(23.40%)with liver cirrhosis presented with hepatic *** with liver cirrhosis were more likely than non-cirrhotic patients to have combined ground-glass opacities and consolidations in CT chest scans:28(43.75%)vs 4(6.55%),respectively(P valueese patients also were more likely to have severe COVID-19 infection,compared to patients without liver cirrhosis:29(45.31%)vs 11(18.04%),respectively(P valueer in patients with liver cirrhosis,compar

关键词： COVID-19 egypt Outcome Liver cirrhosis Chronic hepatitis C

epidural Hematoma after the Use of Subcutaneous Unfractionated Heparin and History of epidural Tumor

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Open Journal of Anesthesiology 2014年第7期4卷 163-166页

作者： basem A. Abdelfattah Troy Buck Scott Byram Department of Anesthesiology Loyola University Medical Center Maywood IL USA

The patient was a 66-year-old male with a history of renal cell carcinoma with metastasis to the L2, L3, and L4 vertebral bodies scheduled for a radical nephrectomy and adrenalectomy. Prior to surgery the patient had undergone 10 radiation treatments for the vertebral metastasis. Patient medications included colace, prednisone, ibuprofen (taken 4 days prior to procedure), sunitinib, hydrocodone, benazepril, nexium, rosuvastatin, allopurinol, and azor. Physical exam prior to surgery was normal with no focal findings. Laboratory values were within normal limits with a platelet count of 286. General anesthesia was planned with a pre-operative thoracic epidural for postoperative analgesia. The epidural was placed at the T9-T10 level without complication. Adequate pain control was present post operatively and the epidural was discontinued on post-operative day 3. At that time the patient was noted to have numbness over the bilateral lower extremities and decreased strength. Heparin 5000 units subcutaneous had been given 12 hours prior to discontinuation of the epidural. The patient was afebrile, hemoglobin was 7, white blood cell count was 9.7, and platelets were 166 at time of epidural removal. Subcutaneous heparin was restarted 6 hours after catheter removal. The anesthesia acute pain service was contacted by the primary service 25 hours after discontinuation of the epidural catheter regarding complaints of persistentbilateral lower extremity weakness and sensory loss. An magnetic resonance image (MRI) revealeda focus posterior to the spinal cord at the T10/T11 interspace likely representing a hematoma. A high intensity T2 signal within the central spinal cord at T10/T11 was also observed;likely a vascular infarct. The patient was immediately scheduled for a T9-T10 laminectomy and evacuation of the epidural hematoma. No significant abnormalities were noted in coagulation studies prior to surgery. The patient was discharged on post-operative day 20 with no neurologic de

关键词： epidural Hematoma epidural Metastasis Heparin

evaluation of the Shelf Life of Packaged Roast Beef and Some Treatments for Its extension

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Food and Nutrition Sciences 2016年第3期7卷 205-213页

作者： Tamador Maayah Malak Angor Khaled Al-Marazeeq basem Al-Abdullah Risk Management Unit at Jordan Food and Drug Administration Amman Jordan Al-Huson University College Al-Balqa Applied University Al-Huson Jordan Faculty of Agriculture University of Jordan Amman Jordan

This study was carried out to investigate the effect of nitrite concentration, and abused chilling temperature against proper chilling temperature on the chemical, microbiological and shelf life of roast beef stored at 4°C and 12°C. Three roast beef treatments were formulated to investigate the effect of nitrite concentration (0.006%, 0.012% and 0.018%) and abused chilling temperature (12°C) against control treatment (0.026% nitrite and storage at 4°C) on the chemical, microbiological and shelf life. Results showed that roast beef containing 0.026% nitrite and stored at 4°C for 25 days had the lowest thiobarbituric acid (TBA) value while the highest TBA values were in the treatment containing 0.006% added nitrite, stored at 12°C. The aerobic plate count, enterobacteriaceae, lactic acid bacteria (LAB), and spore former count were increased throughout the storage period which was lower in 0.026% and 0.018% containing nitrite treatments while higher in other two treatments. The lowest percentage of nitrite losses during storage was in the samples having 0.026% added nitrite to roast beef. The results emphasized the risk of abused temperature and the importance of keeping this product under efficient and consistent refrigeration during storage and the use of high nitrite concentration to protect it and elongate its shelf life.

关键词： Roasted Beef Nitrite Chilling Temperature Shelf Life

Regional evaluation of GOCe-Based GGMs with Ground-Based Gravity and GPS/Levelling Data over egypt

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International Journal of Geosciences 2019年第6期10卷 652-668页

作者： Ahmed Saadon basem elsaka Mohamed el-Ashquer Gamal el-Fiky Construction engineering and Utilities Department Faculty of Engineering Zagazig University Zagazig Egypt National Research Institute of Astronomy and Geophysics (NRIAG) Cairo Egypt Institute of Geodesy and Geoinformation University of Bonn Bonn Germany The Bilbies Higher Institute of engineering Bilbies Egypt

The gravity field and steady-state ocean circulation explorer (GOCe) satellite mission has provided numerous Global Geopotential Models (GGMs) with different processing methodologies and model accuracies. In the current contribution, the latest releases of GOCe-based GGMs are evaluated on the regional scale using the available terrestrial GPS/Levelling and gravity data collected over egypt. To overcome the spectral inconsistency between the GOCe-based GGMs and the ground-based data, the spectral enhancement method (SeM) is applied. Five of GOCe-based GGMs have been used, namely GOSG01S, IGGT_R1, Ife_GOCe05s_ GO_CONS_GCF_2_SPW_R5 (SPW_R5 in the following) and NULP-02. The evaluation process of GOCe-based GGMs with the available ground data over egypt considering the SeM method shows remarkable improvements obtained from the SPW_R5 model. The model provides lower differences of the standard deviations with respect to the eGM2008 and the other applied geopotential gravity models as well as the applied ground-based gravity and GPS/Levelling data. The findings regarding the ground-based data show obvious reductions of about 15.16% and 32.22% achieved by the GOCe-based model in term of standard deviations differences of gravity anomalies and geoid heights, respectively. Therefore, the SPW_R5 model is recommended to be applied as a reference model for compensating the long-to-short wavelength (up to spherical harmonics degree/order 280) components when modelling the gravimetric geoid over egypt.

关键词： GOCe-Based GGMs Gravity Anomalies GNSS/Levelling Spectral enhancement Method (SeM)

Isolation and molecular identification of <i>Ascomycetes</i>in sediments and waters of the Gulf of Aqaba, Red Sea

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Natural Science 2012年第8期4卷 555-561页

作者： basem M. Jaber Rola Al-Silawi Tariq Al-Najjar Department of Biological Sciences The University of Jordan Amman Jordan Department of Marine Biology Faculty of Marine Sciences The University of Jordan/Aqaba Branch Aqaba Jordan

Using molecular approach, we aimed to identify fungal phylotypes that exist in the Gulf of Aqaba, Red sea. Several samples were taken from sediments and seawater of three locations along 26 kilometers at 5 m depth. 18S small subunit rRNA gene was targeted for PCR amplification and sequencing. Partial sequences introduced as query in BLASTN phylogenetic analysis revealed 100% identity with Ascomycota, namely, Aspergillus sp. Penicillium sp. and its closely related eupenicillium sp. The top scorer species in this analysis were Aspergillus sydowii, Aspergillus wentii, Aspergillus flocculosus, Penicillium expansum and eupenicillium javanicum with 98% - 100% identity. Phylogenetic analyses demonstrates close relatedness among isolated fungi and potential association with Ascomycetes. This study reports a new geographical location in which facultative marine Ascomycetes exist in, and sheds some light on fungal diversity in Gulf of Aqaba.

关键词： Marine Fungi Ascomycete 18S ssu rRNA Gulf of Aqaba Red Sea

Hypoalbuminemia in colorectal cancer prognosis:Nutritional marker or inflammatory surrogate?

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World Journal of Gastrointestinal Surgery 2015年第12期7卷 370-377页

作者： Bassel Nazha elias Moussaly Mazen Zaarour Chanudi Weerasinghe basem Azab Department of Medicine North Shore-LIJ Staten Island University Hospital Department of General Surgery Arnot Medical Center

Albumin is the single most abundant protein in the human serum. Its roles in physiology and pathology are diverse. Serum albumin levels have been classically thought to reflect the nutritional status of patients. This concept has been challenged in the last two decades as multiple factors, such as inflammation, appeared to affect albumin levels independent of nutrition. In general, cancer patients have a high prevalence of hypoalbuminemia. As such, the role of hypoalbuminemia in patients with colorectal cancer has received significant interest. We reviewed the english literature on the prognostic value of pretreatment albumin levels in colorectal cancer. We also consolidated the evidence that led to the current understanding of hypoalbuminemia as an inflammatory marker rather than as a nutritional one among patients with colorectal cancer.

关键词： Hypoalbuminemia Albumin Colorectalcancer Albumin-to-globulin ratio Cancer survival Systemic inflammatory response Glasgow prognosticscore

Recent advances in endovascular techniques for management of acute nonvariceal upper gastrointestinal bleeding

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World Journal of Gastrointestinal Surgery 2011年第7期3卷 89-100页

作者： Romaric F Loffroy basem A Abualsaud Ming D Lin Pramod P Rao Le2I Laboratory CNRS UMR 5158Department of Vascular and Interventional RadiologyUniversity of Dijon School of MedicineBocage Teaching Hospital2 Bd Maréchal de Lattre de TassignyBP 7790821079 DijonFrance Department of Vascular and Interventional Radiology University of Dijon School of MedicineBocage Teaching Hospital2 Bd Maréchal de Lattre de TassignyBP 7790821079 DijonFrance Clinical Informatics Interventionaland Translational SolutionsPhilips Research North America345 Scarborough RoadBriarcliff ManorNY 10510United States Russell H.Morgan Department of Radiology and Radiological Science Division of Vascular and Interventional RadiologyJohns Hopkins Hospital600 North Wolfe Street Blalock 545BaltimoreMD 21287United States

Over the past two decades,transcatheter arterial embolization has become the first-line therapy for the management of upper gastrointestinal bleeding that is refractory to endoscopic *** in catheter-based techniques and newer embolic agents, as well as recognition of the effectiveness of minimally invasive treatment options,have expanded the role of interventional radiology in the management of hemorrhage for a variety of indications,such as peptic ulcerbleeding,malignant disease,hemorrhagic Dieulafoy lesions and iatrogenic or trauma *** interventions include the following:selective embolization of the feeding artery,sandwich coil occlusion of the gastroduodenal artery,blind or empiric embolization of the supposed bleeding vessel based on endoscopic findings and coil pseudoaneurysm or aneurysm embolization by three-dimensional sac packing with preservation of the parent *** embolization is a fast,safe and effective,minimally invasive alternative to surgery when endoscopic treatment fails to control bleeding from the upper gastrointestinal *** article reviews the various transcatheter endovascular techniques and devices that are used in a variety of clinical scenarios for the management of hemorrhagic gastrointestinal emergencies.

关键词： Upper gastrointestinal bleeding endoscopy Angiography embolization Surgery

Feasibility of 0.02% Nb-Based Microalloyed Steel for the Application of One-Step Quenching and Partitioning Heat Treatment

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Materials Sciences and Applications 2021年第8期12卷 374-387页

作者： basem Tarek eman eL-Shenawy Ahmed el-Sabbagh Mohamed A. Taha Design and Production engineering Department Faculty of Engineering Ain Shams University Cairo Egypt Plastic Deformation Department Central Metallurgical R&D Institute (CMRDI) Cairo Egypt

To attain an enhanced combination of mechanical properties for low alloyed steel, the current study has been made to fulfill that growing need in the industry. Its results are introduced within this paper. One step Quenching and Partitioning (Q&P) heat treatment has been applied on Niobium-based microalloyed steel alloy with 0.2 %C, in the form of 2 mm thickness sheets. The target of this study is to investigate the viability of applying that significantly recommended, results-wise, heat treatment on the highly well-suited alloy steel samples, to achieve the main target of enhanced properties. A single temperature of 275°C was used as quenching and Partitioning temperature. Four Partitioning periods (30, 200, 500, and 1000 Seconds) were used for soaking at the same temperature. The results were analyzed in the light of microstructural investigation and mechanical testing. All applied cycles did not enhance the strength but moderately improved the ductility and toughness, mainly caused by the slightly high soaking temperature used. Niobium impact of grain refining was apparent through all cycles. The cycle of 500 Seconds Partitioning time obtained optimum values at that particular temperature. The 1000 Seconds Cycle obtained the worst combination of properties. A set of recommendations are set. More research is required at this point, where a lower Partitioning temperature is advised. In the light of the applied combination of parameters, the Partitioning period at such temperature is advised to be between 500 and 1000 Seconds. A high probability that periods closer to 500 than 1000 Seconds will produce better results. More research is needed between those two values of Partitioning time to precisely determine the optimum time at that temperature on that specific alloy.

关键词： Nb-Based Microalloyed Steel Advanced High Strength Steel Quenching and Partitioning Retained Austenite Martensite Transformation Automotive Applications

Compressive Strength of Jordanian Cement Mortars

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Open Journal of Civil engineering 2013年第1期3卷 7-12页

作者： Hamadallah Al-Baijat Maria Chiara Bignozzi basem K. Mohd College of engineering Civil Engineering Department Tafilah Technical University Tafilah Jordan University of Bologna Bologna Italy

Mortars have been prepared from six cement Jordanian brands and tested for their compressive strengths at 2, 7 and 28 days. The strength has been related to some physical parameters. It has been concluded that the compressive strength and its development with age has some variations between the different cement brands. There is an inverse linear relationship between compressive strength and water absorption, and a weaker positive relation with density. There is no clear relation between consistency and compressive strength. Inverse linear relations exist between less than 63 microns size fraction and strength. To account for the differences in compressive strength at different ages and using different cement brands, it is very important to identify the type and amount of cement mineral phases using concrete petrography and X-ray diffraction and fluorescence techniques.

关键词： Natural Asset Financial Value Neural Network