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The GPBiCG(m, l) Method for Solving General Matrix equations

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Journal of Mathematical Research with Applications 2019年第4期39卷 408-432页

作者： basem I.Selim Lei DU Bo YU Xuanru ZHU School of Mathematical Sciences Dalian University of Technology Mathematics and Computer Science Department Faculty of Science Menoufia University

The generalized product bi-conjugate gradient(GPBiCG(m,l))method has been recently proposed as a hybrid variant of the GPBi CG and the Bi CGSTAB methods to solve the linear system Ax=b with non-symmetric coefficient matrix,and its attractive convergence behavior has been authenticated in many numerical *** means of the Kronecker product and the vectorization operator,this paper aims to develop the GPBi CG(m,l)method to solve the general matrix equation■ and the general discrete-time periodic matrix equations■ which include the well-known Lyapunov,Stein,and Sylvester matrix equations that arise in a wide variety of applications in engineering,communications and scientific *** accuracy and efficiency of the extended GPBi CG(m,l)method assessed against some existing iterative methods are illustrated by several numerical experiments.

关键词： GPBiCG(m,l) method Krylov Subspace method matrix equations Kronecker product vectorization operator

In vitro efficacy of new synthetic benzimidazole-related compounds against Schistosoma mansoni adult worms

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Asian Pacific Journal of Tropical Medicine 2020年第12期13卷 566-572页

作者： Amira Taman Samia el-Bardicy Menerva Tadros Magda Ayoub basem Mansour Fouad el-Shehabi Samar Nel-Beshbishi Department of Medical Parasitology Faculty of MedicineMansoura UniversityMansoura 35516Egypt Department of Medical Malacology Theodor Bilharz Research InstituteImbabaCairoEgypt Department of Pharmaceutical Chemistry Faculty of PharmacyDelta University for Science and TechnologyGamasa CityMansouraEgypt Department of Biological Sciences and Biotechnology Faculty of ScienceThe Hashemite UniversityZarqa 13115Jordan

Objective:To evaluate the in vitro antischistosomal activity of two new synthetic benzimidazole-related compounds:NBTP-OH and ***:Schistosoma adult worms were recovered from mice infected with Schistosoma mansoni cercaria,washed and then incubated in the culture media with different concentrations of compounds NBTP-OH and NBTP-F up to 72 *** electron microscopy was conducted to report morphological ***:Incubation of adult Schistosoma mansoni with 10 μg/mL of NBTP-OH for 48 h killed 81.25% of *** calculated LC50and LC90 72 h post-incubation were 6.8 μg/mL and 9.8 μg/mL,*** of worms to 10 μg/mL of NBTP-F killed89.5% of worms after 48 h,mostly males(83.3%),the LC50 and LC90 after 72 h of incubation were 4.8 μg/mL and 6.9 μg/mL,*** incubated for 72 h with these compounds revealed swelling and deformity of oral sucker,disorganization and erosion of the tegument when examined with scanning electron ***:NBTP-OH and NBTP-F possess in vitro antischistosomal activities;however,in vivo studies should be conducted to examine their antischistosomal effects..

关键词： Schistosoma synthetic swelling

Factors Affecting Success of Laparoscopic Salpingostomy for Tubal ectopic Pregnancy: One Hundred Case experience

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Open Journal of Obstetrics and Gynecology 2019年第12期9卷 1549-1557页

作者： basem Hamed Amina Nagy Department of Obstetrics and Gynecology Faculty of Medicine Zagazig University Zagazig Egypt

Objective: The aim of this work is to predict those patients who will have a successful laparoscopic salpingostomy from those who will be obligated to go for salpingectomy. Methods: This study included 100 cases of diagnosed ectopic pregnancy in low parity women and was prepared for laparoscopic salpingostomy versus salpingectomy. Clinical data were collected from the patients (parity, gestational age and clinical presentation), b-hcg, ultrasound data (vascularity of the mass, viability of fetal pole and site of the ectopic in relation of the ipsilateral ovary), laparoscopic data (presence of mass invasion of the tube, free fluid in Douglas pouch, start of tubal abortion and site of ectopic). Then we started to do salpingostomy on the antimesenteric border of fallopian tube using the spatula with monopolar diathermy and try to remove the conceptus from the tube with hydro dissection and check bleeding from the implantation site, only cauterization of the edges of the tubes at the site of salpingostomy was allowed. The process was called to be successful if no more bleeding from the fallopian tube and tubes were conserved, but it was a failed procedure if too much bleeding from the bed of fallopian tube and laparoscopic salpingectomy was done. Results: 28 cases (28%) had laparoscopic salpingostomy (success group) and 72 cases (72%) failed salpingostomy and we went for laparoscopic salpingectomy (failure group). 67 cases with the ectopic in the medial 1/2 of the tube (from which 15 case had salpingostomy and 52 cases had salpingectomy) and 33 cases with ectopic in the lateral 1/2 of the tube (from which 12 cases had salpingostomy and 20 cases had salpingectomy) with no significant difference in both groups (P value 0.075). 42 case showed start of tubal abortion of which 24 cases (57.2%) had salpingostomy and 18 cases (42.8%) had salpingectomy with highly significant difference between both groups (P value 0.000). 52 cases during laparoscopy showed invasion of the mass

关键词： Laparoscopy ectopic Salpingectomy

Therapeutic potential of exercise-hormone irisin in Alzheimer's disease

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Neural Regeneration Research 2025年第6期20卷 1555-1564页

作者： eunhee Kim Rudolph eTanzi Se Hoon Choi Genetics and Aging Research Unit MassGeneral Institute for Neurodegenerative DiseaseDepartment of NeurologyMassachusetts General HospitalHarvard Medical SchoolCharlestownMAUSA McCance Center for Brain Health Massachusetts General HospitalBostonMAUSA

Irisin is a myokine that is generated by cleavage of the membrane protein fibronectin type Ⅲ domain-containing protein 5(FNDC5) in response to physical exercise. Studies reveal that irisin/FNDC5 has neuroprotective functions against Alzheimer's disease, the most common form of dementia in the elderly, by improving cognitive function and reducing amyloid-β and tau pathologies as well as neuroinflammation in cell culture or animal models of Alzheimer's disease. Although current and ongoing studies on irisin/FNDC5 show promising results, further mechanistic studies are required to clarify its potential as a meaningful therapeutic target for alleviating Alzheimer's disease. We recently found that irisin treatment reduces amyloid-β pathology by increasing the activity/levels of amyloid-β-degrading enzyme neprilysin secreted from astrocytes. Herein, we present an overview of irisin/FNDC5's protective roles and mechanisms against Alzheimer's disease.

关键词： Alzheimer's disease exercise fibronectin typeⅢdomain-containing protein 5(FNDC5) irisin

A Single Center experience in Biological Therapy for the Treatment of Rheumatoid Arthritis in Saudi Arabia

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Open Journal of Rheumatology and Autoimmune Diseases 2014年第4期4卷 199-206页

作者： Sultana Abdulaziz basem el-Deek Department of Medicine King Fahad Hospital Jeddah KSA King Abdulaziz University Jeddah KSA

Background: Biological therapy is indicated in the treatment of RA (Rheumatoid Arthritis) after failure of disease-modifying anti-rheumatic drugs (DMARDS) by the ACR/eULAR recommendations. The objective of the study is to describe the characteristics of Saudi patients at the initiation of biological therapy and to evaluate clinical effectiveness of this therapy measured by the disease activity score DAS 28. Methods: This was a retrospective cohort study of RA (rheumatoid arthritis) patients in King Fahad Hospital in Jeddah, Saudi Arabia from January 2005-July 2011. Data were collected from the medical records of all RA patients on biological therapy including: demographics, disease characteristics, comorbid illnesses and DAS 28 score over a period of 1 year. Results: 139 patients were studied (mean age 46 ± 13 years), of which 118 (84%) were females;mean duration of affliction with RA was 7.2 years ranging 1-45 years. Rheumatoid factor (RF) was positive in 88 patients (63.3%) and one or more comorbidities were present in 102 patients (73.3%). First choice of biological drug was ADA (Adalimumab) 44 patients (31.7%) and RTX (Rituximab) was the 2nd frequently prescribed biological drug. Mean DAS 28 activity at baseline was in ADA 41 patients (6.10 ± 1.62), eTA (etarnercept) 29 patients (6.64 ± 1.42) and RTX 50 patients (6.7 ± 1.32). Moderate to good eULAR response was obtained in 74%, 85.7% and 53.3% at 6 months in ADA, eTA and RTX patients respectively. Moderate to good eULAR response was obtained in 61.8%, 86.6% and 72% in ADA, eTA AND RTX patients respectively at 1 year of treatment. Therapeutic effectiveness was comparable with the response rates in published observational trials. Conclusion: Our data demonstrate daily clinical practice in management of RA. The pattern of prescription is in agreement with the ACR/eULAR recommendations for initiation of biologicals in the treatment of RA.

关键词： Single Center Rheumatoid Arthritis Saudi Arabia Biological DMARDS Disease Activity Biologics

Free vibration and transient response of double curved beams connected by intermediate straight beams

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Applied Mathematics and Mechanics(english edition) 2025年第1期46卷 37-62页

作者： R.A.JAFARI-TALOOKOLAeI H.GHANDVAR e.JUMAeV S.KHATIR T.CUONG-Le School of Mechanical engineering Babol Noshirvani University of Technology Department of Mechanical engineering Faculty of Engineering New Uzbekistan University University of Business and Science Center for engineering Application and Technology Solutions Ho Chi Minh City Open University

This paper investigates the free vibration and transient response of interconnected structures including double curved beams and intermediate straight beams,which are all constructed from functionally graded porous(FGP) materials. The strain potential and kinetic energies of each beam along with the work done by the external force are calculated. Additionally, a higher-order beam element is introduced to derive stiffness and mass matrices, along with the force vector. The curved and straight beams are discretized, and their assembled stiffness, mass matrices, and force vectors, are *** conditions at the joints are used to derive the total matrices of the entire structure. Subsequently, the natural frequencies and transient response of the system are determined. The accuracy of the mathematical model and the self-developed computer program is validated through the comparison of the obtained results with those of the existing literature and commercial software ANSYS, demonstrating excellent ***, a comprehensive study is conducted to investigate the effects of various parameters on the free vibration and transient response of the considered structure.

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Factors Influencing Customer Acceptance of M-Commerce Services in Jordan

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通讯和计算机（中英文版） 2012年第12期9卷 1424-1436页

作者： basem Al-Louzi Bassam Iss Department of Finance AI-Balqa Applied University Amman 11941 Jordan Al-Balqa Applied University Amman 11941 Jordan

Sensory evaluation of Different Packaged Roast Beef Treatments Designed for the extension of Its Shelf Life

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Food and Nutrition Sciences 2016年第11期7卷 1052-1061页

作者： Tamador Maaya basem Mohammed Al-Abdullah Risk Management Unit at Jordan Food and Drug Administration Amman Jordan Faculty of Agriculture University of Jordan Amman Jordan

This study was carried out to investigate the effect of different nitrite concentrations on the sensory parameters of roast beef including color, flavor, juiciness, texture and overall acceptability. Four roast beef batches were formulated;the first three treatments were with nitrite concentrations of 0.006%, 0.012% and 0.018% and stored at abused chilling temperature (12°C), while the fourth one was a control treatment with 0.026% nitrite and storage at 4°C. Results showed that increasing nitrite concentration from 0.006% to 0.026% enhanced the shelf life of roast beef stored for 7 days without affecting the sensory characteristics whether at 12°C or 4°C since there were no significant differences (P > 0.05) between all treatments regarding color, flavor, juiciness, texture and overall acceptability. These results could direct us to use high nitrite concentration to protect this product and elongate its shelf life without affecting its preference parameters.

关键词： Roast Beef Nitrite Chilling Temperature Shelf Life Sensory evaluation

Determination and Degradation of Potassium Bromate Content in Dough and Bread Samples Due to the Presence of Metals

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American Journal of Analytical Chemistry 2016年第6期7卷 487-493页

作者： Ahmad Abu-Obaid Shatha AbuHasan basem Shraydeh Department of Chemistry An-Najah National University Nablus Palestine

Potassium bromate (PB) is used in bread making as an agent of maturation;however, it is classified as a potential carcinogen. In the present study, a rapid, simple, precise and accurate testing method has been developed to determine the level of bromate ions in bread, which is based on a reaction of bromate ions with iodide ions in acidic medium to produce iodine (I2). The absorbance of iodine (I2) was measured at 352 nm, and bromate ions reacted with iodide during the first 3 minutes after initiation of the reaction. The proposed method has been successfully applied to the determination of bromate ions in commercial bread. In this work, we found that bromate ions alone degraded at about 400°C, however, during bread making they degraded at 150°C - 200°C, this mightbe due to the presence of metals [Fe, Mg, Zn, Mn, Cu and Al] in flour which served as catalysts. In this study we found that the use of two grams (2 g) of PB per bag flour (60 kg) was safe.

关键词： Potassium Bromate Dough Bread Catalyst Flame Atomic Absorption Inductively Coupled Plasma Mass Spectrometry