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Al-driven analysis establishes the single base.substitution signatures as personalized prognostic predictors for five-year survival of gastric cancer

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Genes & Diseases 2024年第4期11卷 73-76页

作者： Zhenzhang Li Lingqing Xu Wen Luo Shaoan Zhangg Chunyu Hou Xiaohong Xu ,Xubei Peng e.Shiju Janak L.Pathak Shizhen Zhang Jiawei Liu Linhai Li Yang Li School of Biomedical engineering The Sixth Affiliated HospitalGuangzhou Medical UniversityGuangzhouGuangdong 511436China College of Mathematics and Systems Science Guangdong Polytechnic Normal UniversityGuangzhouGuangdong 510665China The Second Affiliated Hospital Guangzhou Medical UniversityGuangzhouGuangdong 510260China Center for Learning Sciences and Technologies The Chinese University of Hong KongShatinNew Territories 999077China Affiliated Stomatology Hospital of Guangzhou Medical University Guangzhou Medical UniversityGuangzhouGuangdong 510182China International School of Photonics Cochin University of Science and TechnologyKochiKerala 682022India

Al-driven genetic engineering,as a burgeoning diagnostic tool,can offer predictive information on the five-year survival rate(FYSR)in the setup of a prognostic therapeutic *** approach provides the individuality and accuracy of prognosis for FYSR of gastric cancer(GC).Unlike traditional neoplasm staging criteria,our technique ensures accuracy and individuality without relying on statistical data and empirical study.

关键词： cancer gastric prognosis

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超疏水耐酸碱改性纸张的制备与性能

高等学校化学学报 2024年第8期45卷 148-155页

作者：韩金娥王聃轲钮腾飞江南大学生命科学与健康工程学院无锡214122 江南大学化学与材料工程学院无锡214122

采用可见光促进的原子转移自由基聚合(ATRP)法,实现了叠氮基单体与含氟单体共聚,得到全氟辛酯叠氮苯酯共聚物,并将其应用于纸张表面改性,制成了超疏水耐酸碱改性纸张.研究了聚合物中各单体种类、比例及聚合物分子量对超疏水耐酸碱性能... 详细信息

采用可见光促进的原子转移自由基聚合(ATRP)法,实现了叠氮基单体与含氟单体共聚,得到全氟辛酯叠氮苯酯共聚物,并将其应用于纸张表面改性,制成了超疏水耐酸碱改性纸张.研究了聚合物中各单体种类、比例及聚合物分子量对超疏水耐酸碱性能的影响.此外,还表征了改性纸张的表面微观结构,研究了聚合物与纸张的连接方式,解释了改性纸张的超疏水耐酸碱性能原理.结果表明,当甲基丙烯酸-4-叠氮苯酯与甲基丙烯酸全氟辛酯的摩尔比为1∶4时,全氟辛酯叠氮苯酯共聚物-80改性后的纸张表现出极强的疏水性,水接触角达到165°,并在强酸(pH=1)或强碱(pH=13)环境下维持72 h无明显变化.制备的共聚材料在防水、耐酸碱应用中具有良好的应用前景.

关键词：叠氮单体含氟单体超疏水性耐酸碱改性纸张

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Dynamics of self-hybridized exciton–polaritons in 2D halide perovskites

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Light(Science & Applications) 2024年第1期13卷 13-22页

作者： Surendra B.Anantharaman Jason Lynch Christopher e.Stevens Christopher Munley Chentao Li Jin Hou Hao Zhang Andrew Torma Thomas Darlington Francis Coen Kevin Li Arka Majumdar PJames Schuck Aditya Mohite Hayk Harutyunyan Joshua R.Hendrickson Deep Jariwala Department of electrical and Systems engineering University of PennsylvaniaPhiladelphiaPA19104USA KBR Inc. BeavercreekOH45431USA Air Force Research Laboratory Sensors DirectorateWright-Patterson Air Force BaseOH45433USA Department of Physics University of WashingtonSeattleWA98195USA Department of Physics Emory UniversityAtlantaGA30322USA Department of Chemical and Biomolecular engineering Rice UniversityHoustonTX77005USA Department of Materials Science and Nanoengineering Rice UniversityHoustonTX77005USA Applied Physics Program Smalley‐Curl InstituteRice UniversityHoustonTX77005USA Department of Mechanical engineering Columbia UniversityNew YorkNY10027USA Department of electrical and Computer engineering University of WashingtonSeattleWA98195USA

excitons,bound electron–hole pairs,in two-dimensional hybrid organic inorganic perovskites(2D HOIPs)are capable of forming hybrid light-matter states known as exciton-polaritons(e–Ps)when the excitonic medium is confined in an optical *** the case of 2D HOIPs,they can self-hybridize into e–Ps at specific thicknesses of the HOIP crystals that form a resonant optical cavity with the ***,the fundamental properties of these self-hybridized e–Ps in 2D HOIPs,including their role in ultrafast energy and/or charge transfer at interfaces,remain ***,we demonstrate that>0.5µm thick 2D HOIP crystals on Au substrates are capable of supporting multiple-orders of self-hybridized e–P *** e–Ps have high Q factors(>100)and modulate the optical dispersion for the crystal to enhance sub-gap absorption and *** varying excitation energy and ultrafast measurements,we also confirm energy transfer from higher energy e–Ps to lower energy e–***,we also demonstrate that e–Ps are capable of charge transport and transfer at *** findings provide new insights into charge and energy transfer in e–Ps opening new opportunities towards their manipulation for polaritonic devices.

关键词： charge polar excitation

FATIGUe CRACK PROPAGATION OF Ni-base.SUPeRALLOYS

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Acta Metallurgica Sinica(english Letters) 2005年第1期18卷 55-64页

作者： e.Barbero Dept. of Mechanical & Aerospace engineering West Virginia University Morgantown WV 26506-6106 USA

Time-dependent Fatigue Crack Propagation (FCP) behaviors of five Ni-base.superalloys were investigated at various temperatures under fatigue with various holding times and sustained loading conditions. The new concept of damage zone is defined and employed to evaluate the alloys' resistance to hold-time FCP. A special testing procedure is designed to get the maximum damage zone of the alloys. Udimet 720 and Waspaloy show shorter damage zones than alloys 706 and 718. The fractographical analyses show that the fracture surfaces of the specimens under hold-time fatigue conditions are mixtures with intergranular and transgranular modes. As the extension of holding time per cycle, the portion of intergranular fracture increases, The effects of loading stress intensity, temperature, holding time, alloy chemistry, and alloy mi-crostructure on damage zone and the crack growth behaviors are studied. Hold-time usually increases the alloy's FCP rate, but there are few exemptions. For instance, the steady state hold-time FCP rate of Waspaloy at 760℃ is lower than that without hold-time. The beneficial effect of hold-time was attributed to the creep caused stress relaxation during the hold-time.

关键词： Ni-base.superalloys fatigue crack growth hold-time

Proposed GSSP for the base.of Cambrian Stage 9,coinciding with the first appearance of Agnostotes orientalis, at Duibian, Zhejiang, China

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Science China earth Sciences 2009年第4期52卷 434-451页

作者： Loren e. BABCOCK Gabriella BAGNOLI School of earth Sciences The Ohio State University Department of earth Sciences of Pisa University

exposed in natural outcrops near the Duibian Village, Jiangshan County, Zhejiang Province, China, the Duibian B section is proposed as the boundary stratotype for the base.of an unnamed stage termed provisionally Cambrian Stage 9. The proposed position of the GSSP is 108.12 m above the base.of the Huayansi Formation, at a horizon coinciding with the first appearance of the cosmopolitan agnostoid trilobite Agnostotes orientalis. This horizon coincides also with the first appearance of the cosmopoli-tan polymerid trilobite Irvingella angustilimbata. The section fulfills all the requirements for a GSSP, and the horizon can be constrained not only by the primary stratigraphic marker (A. orientalis) but also with secondary biostratigraphic, chemostratigraphic, and sequence-stratigraphic correlation tools. The first appearance of A. orientalis is one of the most readily recognizable levels in Cambrian, and can be correlated with precision to all paleocontinents.

关键词： Cambrian GSSP FAD of Agnostotes orientalis China chronostratigraphy

“云膜、云壑”及“云上”等释义补正——《汉语大词典》修订手札六则

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语言研究 2024年第3期44卷 60-66页

作者：谢荣娥华学诚中南民族大学文学与新闻传播学院武汉430074 北京语言大学文献术语研究基地北京100083

《汉语大词典》“云膜、云壑”及“云上”等六个词条,或者义项不齐备,或者释义不准确,甚至缺失基本义、常用义。文章将其区别为多义项缺失和单义项缺失两类,举例分析,予以补正。“云膜、云壑”属于前一个类型,或者缺失基本义、复合初义... 详细信息

《汉语大词典》“云膜、云壑”及“云上”等六个词条,或者义项不齐备,或者释义不准确,甚至缺失基本义、常用义。文章将其区别为多义项缺失和单义项缺失两类,举例分析,予以补正。“云膜、云壑”属于前一个类型,或者缺失基本义、复合初义,或者缺失很重要的转义,以致没能构建出词义系统。“云上”等属于后一个类型,基本义和词义系统基本完整,但缺失了很常用的引申义。

关键词：云膜云壑云脚释义修订《汉语大词典》

惩防结合宽严相济深化醉酒危险驾驶的治理——醉酒危险驾驶专题入库参考案例解读

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中国应用法学 2024年第4期 94-104页

作者：醉酒危险驾驶专题入库参考案例编写小组不详

2024年2月27日,人民法院案例库正式上线并面向社会开放。建设人民法院案例库,是进一步完善中国特色案例制度的重要举措,是最高人民法院推出的新的“公共法律服务产品”。人民法院案例库收录最高人民法院发布的指导性案例和经最高人民法... 详细信息

2024年2月27日,人民法院案例库正式上线并面向社会开放。建设人民法院案例库,是进一步完善中国特色案例制度的重要举措,是最高人民法院推出的新的“公共法律服务产品”。人民法院案例库收录最高人民法院发布的指导性案例和经最高人民法院审核入库的参考案例,供各级人民法院和社会公众查询、使用、学习、研究。人民法院案例库动态更新,目前已经收录超过4000件案例,覆盖刑事、民事、行政、国家赔偿、执行5大案件类型,涉及18个审判业务条线。《最高人民法院关于案例指导工作的规定》(法发〔2010〕51号)第7条规定:“最高人民法院发布的指导性案例,各级人民法院审判类似案例时应当参照。”《人民法院案例库建设运行工作规程》(法〔2024〕92号)第19条规定:“各级人民法院审理案件时,应当检索人民法院案例库,严格依照法律和司法解释、规范性文件,并参考入库类似案例作出裁判。”据此,与其他案例明显不同,人民法院案例库收录的指导性案例和参考案例,各级人民法院审理案件时应当参照/参考。尽管入库案例不能作为裁判依据,但可以将类似案例的裁判理由、裁判要旨作为本案裁判考量、理由参引。为进一步做深做实应用法学研究,便于司法实践中正确理解和准确参考入库案例,《中国应用法学》自2024年第4期起开设“入库参考案例专题解读”专栏,以专题形式精选入库参考案例,邀请案例编写者撰写解读文章,对所涉裁判要旨和有关法律适用疑难问题进行解析探讨。本期围绕醉酒危险驾驶刑事案件专题,选取六篇入库参考案例,邀请最高人民法院刑事审判第五庭、研究室和地方法院的法官进行解读。

关键词：法院审理案件指导性案例宽严相济国家赔偿地方法院应用法学刑事案件刑事审判

Microcracking Behaviour of a TiAl-base.Alloy with Different Microstructures during Compression

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Journal of Materials Science & Technology 1998年第5期14卷 415-418页

作者： Zhang, WJ Chen, GL evangelista, e Francesconi, L Univ Sci & Technol Beijing State Key Lab Adv Met & Mat Beijing 100083 Peoples R China Univ Ancona Dept Mech I-60131 Ancona Italy

The microcracking behaviour of TiAl-base. alloys with the duplex and fully-lamellar microstructures was studied during compression. It was found that the fracture involves propagation of the existing microcracks and development of more new nuclei, instead of being a nucleation-controlled event. The lamellar interfaces, especially those having an angle of about 0 similar to 30 degrees C to the loading axis, were found to be the favourable nucleation sites. Microcrack nucleation is likely to be initiated by tensile normal stress concentrated on the lamellar interfaces.

关键词： Titanium alloys

均相和非均相催化微藻脂质提取和酯交换制备生物燃料的研究进展

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Chinese Journal of Catalysis 2024年第4期59卷 97-117页

作者： Vinoth Kumar Ponnumsamy Hussein e.Al-Hazmi Sutha Shobana Jeyaprakash Dharmaraja Dipak Ashok Jadhav Rajesh Banu J Grzegorz Piechota Bartłomiej Igliński Vinod Kumar Amit Bhatnagar Kyu-Jung Chae Gopalakrishnan Kumar 高雄医科大学药物与应用化学系环境医学研究中心中国台湾高雄高雄医科大学医学研究部中国台湾高雄格但斯克理工大学土木与环境工程学院波兰纳鲁特维察格但斯克范朗大学工程与技术学院建筑绿色技术与可持续发展研究组越南胡志明市工程技术学院科学与人文系化学部印度泰米尔纳德邦韩国海洋大学海洋科学与工程学院环境工程系韩国釜山泰米尔纳德邦中央大学生命科学系印度泰米尔纳德邦 GPCHeM沼气研究与分析实验室波兰尼古拉斯哥白尼大学化学系波兰克兰菲尔德大学水与能源学院英国拉彭兰塔工业大学工程科学学院分离科学系芬兰韩国海洋大学海洋可再生能源工程专业韩国釜山延世大学土木与环境工程学院韩国首尔斯塔万格大学科学技术学院化学、生物科学与环境工程研究所挪威斯塔万格

随着化石燃料燃烧导致的二氧化碳排放不断加剧气候变化,且化石燃料储量日益减少,寻求可再生能源已成为一项紧迫的任务.其中,藻类衍生可持续燃料因具有成本优势和可运输性,在解决全球能源危机方面展现出广阔前景,备受关注.利用化学转化... 详细信息

随着化石燃料燃烧导致的二氧化碳排放不断加剧气候变化,且化石燃料储量日益减少,寻求可再生能源已成为一项紧迫的任务.其中,藻类衍生可持续燃料因具有成本优势和可运输性,在解决全球能源危机方面展现出广阔前景,备受关注.利用化学转化技术从微藻中提取脂质,并通过酯交换反应可以将其转化为脂肪酸甲酯,是生产绿色生物燃料的有效途径.这一过程涉及游离脂肪酸、磷脂和甘油三酯的提取,并且生产过程能耗低,成为满足日益增长的能源需求的一种理想解决方案.本文综述了微藻脂质提取和酯交换制备生物燃料的相关研究进展.首先,介绍了微藻脂质的提取方法,包括溶剂提取法、索氏提取法、布利格和戴耶法、超临界二氧化碳提取以及离子液体溶剂法等,并分析了各方法的优缺点.随后,重点阐述了酯交换技术在微藻脂质转化中的应用,包括酸碱催化、酶催化以及原位酯交换反应等,并探讨了这些技术的反应机理、催化剂选择、反应器设计以及生物油生产工艺等方面的研究进展.通过综述上述研究进展,为微藻脂质的生产和应用提供了理论指导.研究表明,通过优化催化剂种类、反应条件以及提取方法,可以有效提高微藻脂质的转化效率和生物油品质.同时,本文也指出了当前微藻脂质生产中面临的挑战,如微藻栽培和生长条件优化、高效转化技术的开发等.随着可持续能源日益受到重视,微藻脂质作为一种可再生能源具有巨大的发展潜力.未来研究应进一步关注微藻的规模化栽培、生长条件优化以及高效转化技术的研发,以提高微藻脂质的产量和品质.同时,应进一步推动和实现微藻生物燃料的实际应用,从而为应对气候变化和能源危机提供有效的解决方案.

关键词：微藻脂质提取酯交换催化酶催化原位技术