检索结果-南通市图书馆

Intraoperative application of three-dimensional printed guides in total hip arthroplasty: A systematic review

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Orthopedics 2024年第7期15卷 660-667页

作者： Tim P Crone bart m W Cornelissen Jakob Van Oldenrijk Pieter Koen Bos Ewout S Veltman Department of Orthopedic Surgery and Sports medicine Erasmus Medical CenterRotterdam 3015 GDNetherlands Department of Oral and maxillofacial Surgery Erasmus Medical CenterRotterdam 3015 GDNetherlands

BACKGROUND Acetabular component positioning in total hip arthroplasty(THA)is of key importance to ensure satisfactory post-operative outcomes and to minimize the risk of *** majority of acetabular components are aligned freehand,without the use of navigation *** specific instruments(PSI)and three-dimensional(3D)printing of THA placement guides are increasingly used in primary THA to ensure optimal *** To summarize the literature on 3D printing in THA and how they improve acetabular component *** Pubmed was used to identify and access scientific studies reporting on different 3D printing methods used in *** studies with 236 hips in 228 patients were *** studies could be divided into two main categories;3D printed models and 3D printed *** 3D printing in THA helped improve preoperative cup size planning and post-operative Harris hip scores between intervention and control groups(P=0.019,P=0.009).Otherwise,outcome measures were heterogeneous and thus difficult to *** overarching consensus between the studies is that the use of 3D guidance tools can assist in improving THA cup positioning and reduce the need for revision THA and the associated *** The implementation of 3D printing and PSI for primary THA can significantly improve the positioning accuracy of the acetabular cup component and reduce the number of complications caused by malpositioning.

关键词： Total hip arthroplasty Three-dimensional printing Hip replacement surgery Three-dimensional planning Surgical guides

Inflammatory myofibroblastic tumor from molecular diagnostics to current treatment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Oncology Research 2024年第7期32卷 1141-1162页

作者： PAULINA CHmIEL ALEKSANDRA SŁOWIKOWSKA ŁUKASZ BANASZEK ANNA SZUmERA-CIEĆKIEWICZ bartŁOmIEJ SZOSTAKOWSKI mATEUSZ J.SPAŁEK TOmASZŚWITAJ PIOTR RUTKOWSKI ANNA m.CZARNECKA Department of Soft Tissue/Bone Sarcoma and melanoma Maria Sklodowska-Curie National Research Institute of OncologyWarsaw02-781Poland Faculty of medicine Medical University of WarsawWarsaw02-091Poland Department of Pathology Maria Sklodowska Curie National Research Institute of OncologyWarsaw02-781Poland Department of Radiotherapy Maria Sklodowska-Curie National Research Institute of OncologyWarsaw02-781Poland

Inﬂammatory myoﬁbroblastic tumor(ImT)is a rare neoplasm with intermediate malignancy characterized by a propensity for recurrence but a low metastatic *** challenges arise from the diverse pathological presentation,variable symptomatology,and lack of different imaging ***,ImT is identiﬁed by the fusion of the anaplastic lymphoma kinase(ALK)gene,which is present in approximately 70%of cases,with various fusion partners,including ran-binding protein 2(RANBP2),which allows conﬁrmation of the *** surgery is the preferred approach for localized tumors,the optimal long-term treatment for advanced or metastatic disease is difﬁcult to deﬁ*** therapies are crucial for achieving sustained response to treatment within the context of genetic alteration in ***,an ALK tyrosine kinase inhibitor(TKI),was ofﬁcially approved by the US Food and Drug Administration(FDA)in 2020 to treat ImT with ALK ***,most patients face resistance and disease progression,requiring consideration of sequential *** radiotherapy with targeted therapy appears to be beneﬁcial in this *** promising results have also been achieved with immunotherapy,indicating potential for combined therapy ***,deﬁned recommendations are still *** review analyzes the available research on ImT,including genetic disorders and their impact on the course of the disease,data on the latest targeted therapy regimens and the possibility of developing immunotherapy in this indication,as well as summarizing general knowledge about prognostic and predictive factors,also in terms of resistance to systemic therapy.

关键词： Inﬂammatory myoﬁbroblastic tumor(ImT) Epithelioid inﬂammatory myoﬁbroblastic sarcoma Tyrosine kinase inhibitors(TKI) Anaplastic lymphoma kinase(ALK)

Supramolecular Polymerization of Hydrogen-Bonded Trimers in Bulk and Aqueous medium

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

CCS Chemistry 2024年第6期6卷 1458-1465页

作者： Freek V.de Graaf Stef A.H.Jansen Sandra m.C.Schoenmakers Bas van Genabeek marle E.J.Vleugels bart W.L.van den Bersselaar E.W.meijer Ghislaine Vantomme Institute for Complex molecular Systems Laboratory of Macromolecular and Organic ChemistryEindhoven University of Technology5600 MBEindhoven School of Chemistry and RNA Institute University of New South WalesSydneyNew South Wales 2052

Synthetic molecules that form functional noncovalent assemblies in water have received much attention for their potential applications as *** this work,we introduce a novel water-compatible monomer based on the phthalhydrazide moiety that assembles into hydrogen-bonded trimeric *** bulk,the material exhibits a cylindrical nanostructure in the liquid-crystalline phase at elevated temperatures,morphologically distinct from the crystalline lamellar *** water,these molecules effectively form cylinders in a one-dimensional fashion,yielding fibrous *** formation of these supramolecular polymers follows a cooperative mechanism,as evidenced by denaturation *** trimerized pattern represents a new category of aqueous su pramolecular polymers with future prospects for functional complex molecular systems.

关键词： noncovalent chemistry supramolecular polymers hydrogen bonding cooperativity nanostructure

Flapping vortex dynamics of two coupled side-by-side flexible plates submerged in the wake of a square cylinder

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Fluid Engineering

International Journal of Fluid Engineering 2024年第1期 40-55页

作者： Bin Xu Hao Wang Weibin Zhang Yilin Deng Xi Shen Desheng Zhang B.P.m.(bart) van Esch Research Center of Fluid machinery Engineering and Technology Jiangsu University Key Laboratory of Fluid and Power machinery(Xihua University) Ministry of Education Institute for Energy Research Jiangsu University Eindhoven University of Technology

The flapping vortex dynamics of two flexible plates submerged side-by-side in the wake of a square cylinder are investigated through a two-way fluid–structure interaction(FSI) simulation. The gap between the two plates can stabilize wakes, lengthen vortex formation,elongate vortices, suppress vortex shedding, and decrease hydrodynamic forces. The numerical results indicate that the two flexible plates can exhibit four distinct modes of coupled motion: out-of-phase flapping, in-phase flapping, transition flapping, and decoupled flapping,depending on the gap spacing. Additionally, it is discovered that each of the four coupling modes has a unique pattern of vortex development. The findings of this study should proved valuable in the design of FSI-based piezoelectric energy harvesters utilizing cylinder–plate systems.

关键词：

Single-emitter super-resolved imaging of radiative decay rate enhancement in dielectric gap nanoantennas

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

Light(Science & Applications) 2024年第1期13卷 47-54页

作者： R.margoth Córdova-Castro bart van Dam Alberto Lauri Stefan A.maier Riccardo Sapienza Yannick De Wilde Ignacio Izeddin Valentina Krachmalnicoff Institut Langevin ESPCI ParisPSL UniversityCNRSParisFrance The Blackett Laboratory Department of PhysicsImperial College LondonLondonUK School of Physics and Astronomy Monash UniversityClaytonVictoriaAustralia Chair in Hybrid Nanosystems Ludwig-Maximilians Universität MünchenMuenchenGermany Department of Physics University of OttawaOttawaONCanada

High refractive index dielectric nanoantennas strongly modify the decay rate via the Purcell effect through the design of radiative *** to their dielectric nature,the field is mainly confined inside the nanostructure and in the gap,which is hard to probe with scanning probe *** we use single-molecule fluorescence lifetime imaging microscopy(smFLIm)to map the decay rate enhancement in dielectric GaP nanoantenna dimers with a median localization precision of 14 *** measure,in the gap of the nanoantenna,decay rates that are almost 30 times larger than on a glass *** comparing experimental results with numerical simulations we show that this large enhancement is essentially radiative,contrary to the case of plasmonic nanoantennas,and therefore has great potential for applications such as quantum optics and biosensing.

关键词： dielectric decay radiative

SImAP500: A novel risk score to identify recipients at higher risk of hepatocellular carcinoma recurrence following liver transplantation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Transplantation 2024年第3期14卷 132-143页

作者： Amr Alnagar Nekisa Zakeri Konstantinos Koilias Rosemary E Faulkes Rachel Brown Owen Cain m Thamara P R Perera Keith J Roberts Rebeca Sanabria-mateos David C bartlett Yuk Ting ma Shivan Sivakumar Shishir Shetty Tahir Shah Bobby V m Dasari Department of HBP and Liver Transplantation Surgery Queen Elizabeth HospitalUniversity Hospitals BirminghamBirmingham B152GWUnited Kingdom Centre for Liver Research Institute of Biomedical ResearchBirmingham B152TTUnited Kingdom Department of Hepatology Queen Elizabeth HospitalUniversity Hospitals BirminghamBirmingham B152GWUnited Kingdom Department of Pathology University Hospitals Birmingham NHS Foundation TrustBirmingham B152GWUnited Kingdom Department of Oncology Queen Elizabeth HospitalUniversity Hospitals of BirminghamBirmingham B152GWUnited Kingdom

BACKGROUND Recurrence of hepatocellular carcinoma(HCC)following liver transplantation(LT)has a devastating influence on recipients’survival;however,the risk of recur-rence is not routinely *** stratification is vital with a long LT waiting time,as that could influence the recurrence despite strict listing *** This study aims to identify predictors of recurrence and develop a novel risk pre-diction score to forecast HCC recurrence following *** A retrospective review of LT for HCC recipients at University Hospitals Bir-mingham between July 2011 and February *** and multivariate analyses were performed to identify recurrence predictors,based on which the novel SImAP500(satellite nodules,increase in size,microvascular invasion,AFP>500,poor differentiation)risk score was *** 234 LTs for HCC were performed with a median follow-up of 5.3 *** developed in 25 patients(10.7%).On univariate analyses,RETREAT score>3,α-fetoprotein(AFP)at listing 100-500 and>500,bridging,increased tumour size between imaging at the listing time and explant histology,increase in the size of viable tumour between listing and explant,presence of satellite nodules,micro-and macrovascular invasion on explant and poor differentiation of tumours were significantly associated with recurrence,based on which,the SImAP500 risk score is *** SImAP500 demonstrated an excellent predictive ability(c-index=0.803)and outper-formed the RETREAT score(c-index=0.73).SImAP500 is indicative of the time to disease *** SImAP500 risk score identifies the LT recipients at risk of HCC *** stratification allows patient-centric post-transplant surveillance *** validation of the score is recommended.

关键词： Liver transplantation Hepatocellular carcinoma Recurrence Survival

New insights into the regulation of cholesterol eft from the sperm membrane

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Journal of Andrology 2015年第4期17卷 561-567页

作者： Tamara Leahy bart m Gadella Faculty of Veterinary Science University of Sydney 2006 Sydney Australia Department of Farm Animal Health and of Biochemistry and Cell Biology Faculty ofVeterinary Medicine Utrecht University Yalelaan 2 3584 CM Utrecht The Netherlands.

Cholesterol is an essential component of the mammalian plasma membrane because it promotes membrane stability without comprising membrane fluidity. Given this important cellular role, cholesterol levels are tightly controlled at multiple levels. It has been clearly shown that cholesterol redistribution and depletion from the sperm membrane is a key part of the spermatozoon＇s preparation for fertilization. Some factors that regulate these events are described （e.g., bicarbonate, calcium） but the mechanisms underlying cholesterol export are poorly understood. How does a hydrophobic cholesterol molecule inserted in the sperm plasma membrane enter the energetically unfavorable aqueous surroundings？ This review will provide an overview of knowledge in this area and highlight our gaps in understanding. The overall aim is to better understand cholesterol redistribution in the sperm plasma membrane, its relation to the possible activation of a cholesterol transporter and the role of cholesterol acceptors. Armed with such knowledlze, sl）erm handlin~ techniques can be adapted to better prepare spermatozoa for in vitro and in vivo fertilization.

关键词： ATP binding cassette transporters albumin high-density lipoprotein lipid rafts membrane fluidity membranemicrodomains membrane packing oxysterols reverse cholesterol transport sterol transporters

Initial impacts of rain gardens＇ application on water quality and quantity in combined sewer： field-scale experiment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Frontiers of Environmental Science & Engineering 2017年第4期11卷 127-138页

作者： Isam Alyaseri Jianpeng Zhou Susan m. morgan Andrew bartlett Department of Civil Engineering Al-Muthanna University Alsamawah Al-Muthanna 72001 Iraq Department of Civil Engineering Southern Illinois University Edwardsville Edwardsville IL 62026 USA Graduate School Southern Illinois University Edwardsville Edwardsville IL 62026 USA Agricultural Statistics Laboratory University of Arkansas Fayetteville AR 72701 USA

Green infrastructures such as rain gardens can benetit onsite reduction ot stormwater runott, leading to reduced combined sewer overflows. A pilot project was conducted to evaluate the impact of rain gardens on the water quality and volume reduction of storm runoff from urban streets in a combined sewer area. The study took place in a six-block area on South Grand Boulevard in St. Louis, missouri. The impact was assessed through a comparison between the pre-construction （2011/2012） and the post-construction （2014） phases. Shortly after the rain gardens were installed, the levels of total suspended solids, chloride, total nitrogen, total phosphorous, zinc, and copper increased. The level of mercury was lower than the detection level in both phases. E. coli was the only parameter that showed statistically significant decrease following the installation of rain gardens. The likely reason for initial increase in monitored water quality parameters is that the post-construction sampling began after the rain gardens were constructed but before planting, resulted from soil erosion and wash-out from the mulch. However, the levels of most of water quality parameters decreased in the following time period during the post-construction phase. The study found 76% volume reduction of stormwater runoff following the installation of rain gardens at one of studied sites. Statistical analysis is essential on collected data because of the encountered high variability of measured flows resulted from low flow conditions in studied sewers.

关键词： Rain gardens Bioretention Combined sewer Stormwater quality and quantity

Parameter Ecology for Feedback Vertex Set

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Tsinghua Science and Technology 2014年第4期19卷 387-409页

作者： bart m.P.Jansen Venkatesh Raman martin Vatshelle the Department of Informatics University of Bergen 5005 Bergen Norway the Institute of mathematical Sciences Chennai India

This paper deals with the FEEDBACK VERTEX SET problem on undirected graphs, which asks for the existence of a vertex set of bounded size that intersects all cycles. Due it is theoretical and practical importance,the problem has been the subject of intensive study. motivated by the parameter ecology program we attempt to classify the parameterized and kernelization complexity of FEEDBACK VERTEX SET for a wide range of *** survey known results and present several new complexity classifications. For example, we prove that FEEDBACK VERTEX SET is fixed-parameter tractable parameterized by the vertex-deletion distance to a chordal graph. We also prove that the problem admits a polynomial kernel when parameterized by the vertex-deletion distance to a pseudo forest, a graph in which every connected component has at most one cycle. In contrast, we prove that a slightly smaller parameterization does not allow for a polynomial kernel unless NP coNP=poly and the polynomial-time hierarchy collapses.

关键词： feedback vertex set parameterized complexity parameter ecology program structural parameterizations kernelization