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中国神经科学学会第四次会员代表大会暨第七届全国学术会议

作者： Ze’ev SELTZER barry j.SESSLE james HU University of Toronto Centre for the Study of Pain TorontoOntarioM5G1G6Canada

＜正＞Neuropathic pain following nerve injury in humans may spread to areas far beyond the territory of the injured nerve（"Extraterritorial pain"） and contralaterally（"Mirror image pain"）,and in extreme cases occupy large body parts. Certain trigeminal pain syndromes are more prevalent in women than *** aims of this study are 1) to produce a model of trigeminal neuropathic pain in mice of the A/j,C57BL/6j（’B6’） and DBA/2j inbred strains;2) to compare the pain spread in this model in male and female mice,in order to recommend the recombinant inbred（RI） mice lines,which provide a powerful assay to identify Quantitative Trait Loci（QTLs） for chronic pain *** hundred and twenty adult male and female mice of A/j,DBA/2j,B6 strains were divided into 12 groups（n = 10 mice per strain,gender,sham and nerve- injury groups）.The tactile allodynia-like behavior was determined as the average response score to 3 separate poking trials with a stiff Von Frey hair applied to the ears,the plantar surface of the forepaws and hindpaws bilaterally,and the middle part of the tail on days -8 and -2（preoperatively）,and days 1,3,8,13 and 20 postoperatively（TO’）.Heat hyperlagesia was determined from the frequency of withdrawal responses to 5 noxious heat stimuli delivered from an infrared diode laser to the same loci as the tactile allodynia test except for the forepaws on days -10 and -3（preoperatively）,and days 7,14,21,35 and 49 *** males,we found that unilateral ION-X produced significant tactile allodynia in the contralateral ear of A/j *** tactile allodynia was found in other loci of them and in any loci in other ***-X did not produce significant heat hyperalgesia in any tested loci of all three mice ***,heat hyperalgesia was demonstrated in the contralateral ear of female A/j mice and in the tail of female A/j and DBA/2j mice,on d 14 and d 21 *** transection of the infra-orbital nerve produces in mice tactile allodynia and heat hyper

关键词： wide-spread neuropathic pain infraorbital neurectomy recombinant inbred mice quantitative trait loci trigeminal neuropathy

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黏土中静压沉桩离心模型

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工程科学学报 2018年第3期40卷 285-292页

作者：李雨浓 barry M Lehane 刘清秉燕山大学建筑工程与力学学院秦皇岛066004 西澳大学土木工程与资源学院珀斯6009 中国地质大学武汉三峡研究中心武汉430074

采用西澳大学室内鼓轮式离心机,在预先固结的高岭黏土中开展不同离心力场（50g,125g及250g,g为重力加速度）条件下的模型压桩试验、T-bar试验和静力触探试验,分析了模型桩在贯入过程、静置稳定过程中桩身径向应力（σr）的变化规律,并... 详细信息

采用西澳大学室内鼓轮式离心机,在预先固结的高岭黏土中开展不同离心力场（50g,125g及250g,g为重力加速度）条件下的模型压桩试验、T-bar试验和静力触探试验,分析了模型桩在贯入过程、静置稳定过程中桩身径向应力（σr）的变化规律,并对后期桩体拉伸载荷阶段的径向应力变化值（Δσr）及桩侧摩阻力变化情况行了探讨,揭示了在不同超固结比（OCRs）黏土中静压桩侧摩阻力的演变特性.在此基础上,通过两种经验公式方法对桩侧摩承载力进行了预测计算和对比分析.研究结果表明：沉桩过程中桩端相对高度（h/B）对桩身径向应力的发展变化有很大的影响,桩身不同位置（h/B）的总径向应力对同一贯入深度而言,存在桩侧径向应力退化现象;基于静力触探试验提出的经验方法,能有效考虑静力触探锥端阻力（qt）和桩端相对高度（h/B）因素的影响,将其应用于黏土沉桩时桩侧摩阻力的预测,可取得与试验实测结果较吻合的结果.研究成果对软土地区静压桩施工与承载力设计具有一定的工程指导意义.

关键词：静压桩径向应力黏土桩侧承载力离心模型

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Postpartum meloxicam administration alters plasma haptoglobin, polyunsaturated fatty acid, and oxylipid concentrations in postpartum ewes

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journal of Animal Science and Biotechnology 2020年第4期11卷 1047-1060页

作者： Katie EOlagaray barry j.Bradford Lorraine M.Sordillo jeffery C.Gandy Laman K.Mamedova Turner H.Swartz Trey D.jackson Emma K.Persoon Caitlin S.Shugart Curtis R.Youngs Department of Animal Sciences and Industry Kansas State UniversityManhattan 66506USA College of Veterinary Medicine Michigan State University2265K Anthony HallEast LansingMI 48824-1225USA Department of Animal Science Iowa State UniversityAmesIAUSA.

Background: Postpartum inflammation is a natural and necessary response;however, a dysfunctional inflammatory response can be detrimental to animal productivity. The objective of this study was to determine the effects of a non-steroidal anti-inflammatory drug(meloxicam) on ewe postpartum inflammatory response, ewe plasma polyunsaturated fatty acid and oxylipid concentrations, and lamb ***: After lambing, 36 Hampshire and Hampshire × Suffolk ewes were sequentially assigned within type of birth to control(n = 17) or meloxicam orally administered on d 1 and 4 of lactation(MEL;90 mg, n = 19). Milk and blood samples were collected on d 1(prior to treatment) and d 4. Milk glucose-6-phosphate was not affected by MEL. Plasma haptoglobin(Hp) concentrations were less for MEL ewes;control ewes with greater d 1 Hp concentrations had elevated Hp on d 4, but this was not the case for MEL-treated ewes. Treatment with MEL increased plasma arachidonic acid concentration by more than 4-fold in ewes rearing singles but decreased concentrations of 9,10-dihydroxyoctadecenoic acid, prostaglandin F2α, 8-iso-prostaglandin E2, and 8,9-dihydroxyeicosatetraenoic acid. Nine oxylipids in plasma had interactions of treatment with d 1 Hp concentration,all of which revealed positive associations between d 1 Hp and d 4 oxylipid concentrations for CON, but neutral or negative relationships for MEL. MEL decreased 13-hydroxyoctadecadienoic acid:13-oxooctadecadienoic acid ratio and tended to increase 9-hydroxyoctadecadienoic acid:9-oxooctadecadienoic acid ratio(both dependent on d 1 values), indicating progressive metabolism of linoleic acid-derived oxylipids occurred by enzymatic oxidation after MEL treatment. Meloxicam reduced oxylipids generated across oxygenation pathways, potentially due to an improved redox ***: Postpartum MEL treatment of ewes decreased plasma concentrations of Hp and several oxylipids,with the greatest impact in ewes with biomarkers reflecting a greate

关键词： Eicosanoid Inflammation Lactation Nonsteroidal anti-inflammatory drug Sheep

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Making a Bad Situation Worse

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ChinAfrica 2013年第4期5卷 10-11页

作者： barry Sautman Yan Hairong Hong Kong University of Science & Technology Hong Kong Polytechnic University

THE update, like the 2011 HRW report, focuses on safety and implies that Chinese-owned mines are markedly less safe than other foreign-owned copper mines in Zambia. Indeed, the HRW update is titled “Zambia： Safety G... 详细信息

关键词： Bad Making a Bad Situation Worse OC

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Fundamentals and application in phytoremediation of an efficient arsenate reducing bacterium Pseudomonas putida ARS1

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journal of Environmental Sciences 2024年第3期137卷 237-244页

作者： Ze-Wen Wang Guang Yang jian Chen Yaoyu Zhou Avelino Nunez Delgado Hui-Ling Cui Gui-Lan Duan barry P.Rosen Yong-Guan Zhu Henan Institute of Advanced Technology Zhengzhou UniversityZhengzhou 450052China State Key Lab of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085China Department of Cellular Biology and Pharmacology Florida International UniversityHerbert Wertheim College of MedicineMiamiFL33199USA University of Chinese Academy of Sciences Beijing 100049China Key Laboratory of Urban Environment and Health Institute of Urban EnvironmentChinese Academy of SciencesXiamen 361021China College of Resources and Environment Hunan Agricultural UniversityChangsha 410128China Department of Soil Science and Agricultura Chemistry Engineering Polytechnic SchoolUniversity of Santiago de CompostelaCampus Univ.s/n27002LugoSpain

Arsenic is a ubiquitous environmental ***-mediated arsenic biotransformations significantly infuence arsenic mobility and *** transformations by soil and aquatic organisms have been well documented,while little is known regarding effects due to endophytic *** endophyte Pseudomonas putida ARS1 was isolated from rice grown in arsenic contaminated *** ARS1 shows high tolerance to arsenite(As(Ⅲ))and arsenate(As(V)),and exhibits efficient As(V)reduction and As(Ⅲ)effux *** exposed to 0.6 mg/L As(V),As(V)in the medium was completely converted to As(Ⅲ)by *** ARS1 within 4 *** sequencing showed that *** ARS1 has two chromosomal arsenic resistance gene clusters(arsRCBH)that contribute to efficient As(V)reduction and As(Ⅲ)effux,and result in high resistance to *** globosa is a strong arsenic accumulator with high potential for arsenic phytoremediation,which takes up As(Ⅲ)more efficiently than As(V).Co-culture of *** ARS1 and *** enhanced arsenic accumulation in *** by 69%,and resulted in 91%removal of arsenic(at initial concentration of 0.6 mg/L As(V))from water within 3 *** study provides a promising strategy for in situ arsenic phytoremediation through the cooperation of plant and endophytic bacterium.

关键词： Arsenic Pseudomonas putida Arsenate reduction Endophyte Wolffia globosa Phytoremediation

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Effects of hypoxia on coronary flow reserve as determined by myocardial contrast echocardiography in swine

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Chinese Medical journal 2004年第10期117卷 1453-1458页

作者：杨源李树清 barry Peters Anthony N DeMari Department of Cardiology First Affiliated Hospital of Kunming Medical College Kunming 650032 China Department of Cardiology University of California San Diego USA

Background Time-intensity curves derived from microbubble destruction/refilling sequences and recorded using myocardial contrast echocardiography (MCE) can provide parameters that correlate with coronary blood flow. The response of these parameters to adenosine vasodilatation correlates with coronary flow reserve (CFR) measured by fluorescent microsphere techniques (FMT). Currently, no data exist regarding the effect of physiological variables, such as hypoxia, on the determination of CFR by MCE. The purpose of this study was to define the effects of decreases in blood partial pressure of oxygen (PO_2) on CFR as measured by MCE. Methods Studies were performed in 9 closed chest swine. Low-energy, real-time MCE was performed with commercial instruments in short axis view at papillary muscle level while infusing BR_1 at 30 ml/h. High-energy ultrasound bursts (referred to as FLASH frames) destroyed the bubbles every 15 cardiac cycles, and resultant time-intensity curves derived from these sequences were fitted to the exponential function y = A (1-e -bt) +c, from which the rate of signal rise (b) was obtained. CFR was calculated as the ratio of b values after adenosine infusion to baseline and was obtained during the control period and after decreasing blood PO_2 by giving nitrogen via a respirator to create artificial hypoxic conditions. CFR was independently determined by FMT. Results Nitrogen led to significant decreases in mean PO_2, from (120.6±18.9) mmHg to (51.8±15.9) mmHg (P<0.01). Adenosine produced a similar increase in CFR (2.5 fold vs 3.1 fold) as assessed by MCE and FMT during the control period. The decrease in PO_2 post nitrogen resulted in a slight increase in values at rest: 0.46±0.15 to 0.53±0.18 for b and (1.39±0.66) ml·min -1·g -1 to (1.72±0.30) ml·min -1·g -1 for myocardial blood flow (MBF) (both P<0.05). In addition, values decreased in response to adenosine using both techniques: 1.05±0.35 to 0.82±0.27 for b and (4.30±3.16) ml·min -1·g -

关键词： anoxia coronary flow reserve myocardial contrast echocardiography

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Delayed referral for liver transplant evaluation worsens outcomes in chronic liver disease patients requiring inpatient transplant evaluation

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World journal of Transplantation 2023年第4期13卷 169-182页

作者： Katherine M Cooper Alessandro Colletta Nicholas j Hathaway Diana Liu Daniella Gonzalez Arslan Talat Curtis barry Anita Krishnarao Savant Mehta Babak Movahedi Paulo N Martins Deepika Devuni Department of Medicine UMass Chan Medical SchoolWorcesterMA 01605United States Department of Medicine Division of GastroenterologyUMass Chan Medical SchoolWorcesterMA 01605United States Department of Surgery Transplant DivisionUMass Chan Medical SchoolWorcesterMA 01605United States

BACKGROUND Indications to refer patients with cirrhosis for liver transplant evaluation(LTE)include hepatic decompensation or a model for end stage liver disease(MELDNa)score≥*** studies have evaluated how delaying referral beyond these criteria affects patient *** To evaluate clinical characteristics of patients undergoing inpatient LTE and to assess the effects of delayed LTE on patient outcomes(death,transplantation).METHODS This is a single center retrospective cohort study assessing all patients undergoing inpatient LTE(n=159)at a large quaternary care and liver transplant center between 10/23/2017-7/31/*** referral was defined as having prior indication(decompensation,MELD-Na≥15)for LTE without *** referral was defined as referrals made within 3 mo of having an indication based on practice *** regression and Cox Hazard Regression were used to evaluate the relationship between delayed referral and patient *** Many patients who require expedited inpatient LTE had delayed *** regarding transplant candidacy were a leading cause of delayed ***,delayed referrals negatively affected overall patient outcome and an independent predictor of both death and not receiving a *** referral was associated with a 2.5 hazard risk of *** Beyond initial access to an liver transplant(LT)center,delaying LTE increases risk of death and reduces risk of LT in patients with chronic liver *** is substantial opportunity to increase the percentage of patients undergoing LTE when first clinically *** is crucial for providers to remain informed about the latest guidelines on liver transplant candidacy and the transplant referral process.

关键词： Liver transplantation Liver transplant evaluation Liver transplant referral Patient access Equity Patient outcomes

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世界历史的分期与国际体系的演变

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史学集刊 2003年第1期 1-9页

作者： barry Buzan 刘德斌伦敦经济学院国际关系系

本文在介绍、分析和批判西方学术界世界历史权威分期法的同时 ,从国际体系演变的角度 ,提出了人类从 6 0 ,0 0 0年前分散的采猎群到今天全球经济政治高度一体化的新的历史分期法。作者以一种全新博大的历史观对西方历史学和国际关系学... 详细信息

本文在介绍、分析和批判西方学术界世界历史权威分期法的同时 ,从国际体系演变的角度 ,提出了人类从 6 0 ,0 0 0年前分散的采猎群到今天全球经济政治高度一体化的新的历史分期法。作者以一种全新博大的历史观对西方历史学和国际关系学两大领域的主流理论提出了挑战。本文摘译自作者《世界史中的国际体系 :国际关系研究的再构建》一书。作者认为正是由于历史研究的匮乏 ,致使西方主流国际关系理论陷于只能孤芳自赏的境地。而只有融理论研究于历史探讨 ,建立一个超越现有诸种框架之上的新时空观 ,国际关系研究才能走出误区 ,真正对社会现实和其他学科产生影响。

关键词：世界历史国际体系转折点

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Business forecasting with accompanying Excel-based ForecastX software

Business forecasting with accompanying Excel-based ForecastX...

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1942年

作者： j. Holton Wilson barry Keating.

来源：畅想之星图书光盘版（南... 评论

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Principles and practices of training for soccer

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journal of Sport and Health Science 2014年第4期3卷 251-257页

作者： Ryland Morgans Patrick Orme Liam Anderson barry Drust Liverpool Football Club Melwood Training GroundDeysbrook LaneLiverpoolL12 8SY.UK School of Sport Cardiff Metropolitan UniversityCardiff CF23 6XDUK Research Institute for Sport and Exercise Sciences Liverpool John Moores UniversityLiverpoolL3 3AFUK

The complexity of the physical demands of soccer requires the completion of a multi-component training programme. The development, planning, and implementation of such a programme are difficult due partly to the practical constraints related to the competitive schedule at the top level. The effective planning and organisation of training are therefore crucial to the effective delivery of the training stimulus for both individual players and the team. The aim of this article is to provide an overview of the principles of training that can be used to prepare players for the physical demands of soccer. Information relating to periodisation is supported by an outline of the strategies used to deliver the acute training stress in a soccer environment. The importance of monitoring to support the planning process is also reviewed.

关键词： Monitoring Periodisation Soccer Small-sided games Training

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