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细胞浆内精子注射受孕、体外授精受孕、自然受孕出生的儿童5岁时结局的国际合作研究:认知和运动能力评价

世界核心医学期刊文摘（儿科学分册） 2006年第11期2卷 41-43页

作者： Ponj.ert-Kristoffersen I Bonduelle M. barnes j. A.G. Sutcliffe 王经纬 Royal Free and University College Medical School University College London NW3 2PF United Kingdom Dr.

Obj.ctive. To date, very few studies have been conducted on the neurodevelopmental well-being of children conceived through intracytoplasmic sperm inj.ction (ICSI). The limitations of these studies often include a lack of comparison with a demographically matched, naturally conceived (NC) group and the investigation of only very young children, with relatively small samples sizes. One study showed that there were no differences in IQ scores among ICSI-conceived, in vitro fertilization (IVF)-conceived, and NC children at 5 years of age. Unfortunately, psychomotor development was not assessed in that study. Because findings regarding these children’s cognitive and motor development are inconclusive, the aim of this study was to shed more light on the cognitive and motor development of 5-year-old ICSI-conceived children. Methods. A total of 511 ICSI-conceived children were compared with 424 IVF-conceived children and 488 NC controls. Children were recruited in 5 European countries, ie, Belgium, Denmark, Greece, Sweden, and the United Kingdom. Participation rates ranged from 45%to 96%in the ICSI and IVF groups and from 34%to 78%in the NC group. Cognitive and motor development was assessed with the Wechsler Preschool and Primary Scale of Intelligence-Revised (WPPSI-R) and McCarthy Scales of Children’s Abilities (MSCA) Motor Scale, respectively. The WPPSI-R consists of 2 maj.r scales, ie, Verbal and Performance, each including 6 subtests. The 6 Performance Scale subtests are obj.ct assembly, geometric design, block design, mazes, picture completion, and animal pegs. The 6 Verbal Scale subtests are information, comprehension, arithmetic, vocabulary, similarities, and sentences. Scores on the Performance and Verbal Scale subtests are summed to yield the performance IQ (PIQ) and verbal IQ (VIQ), respectively. Scores on both the Performance Scale and the Verbal Scale yield the full scale IQ (FSIQ). IQ scales have a mean score of 100 and a SD of 15. Each subtest has a mean sco

关键词：体外授精细胞浆国际合作研究操作量表生殖技术精神运动发育儿童认知人口统计学样本量无显

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Release, Recycle, Rebuild： Cell-Wall Remodeling, Autodegradation, and Sugar Salvage for New Wall Biosynthesis during Plant Development

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Molecular Plant 2018年第1期11卷 31-46页

作者： William j. barnes Charles T. Anderson Department of Biology Center for Ugnocellulose Structure and Formation The Pennsylvania State University University Park PA 16802 USA

Plant cell walls contain elaborate polysaccharide networks and regulate plant growth, development, mechanics, cell-cell communication and adhesion, and defense. Despite conferring rigidity to support plant structures, the cell wall is a dynamic extracellular matrix that is modified, reorganized, and degraded to tightly control its properties during growth and development. Far from being a terminal carbon sink, many wall polymers can be degraded and recycled by plant cells, either via direct re-incorporation by trans- glycosylation or via internalization and metabolic salvage of wall-derived sugars to produce new precur- sors for wall synthesis. However, the physiological and metabolic contributions of wall recycling to plant growth and development are largely undefined. In this review, we discuss long-standing and recent evi- dence supporting the occurrence of cell-wall recycling in plants, make predictions regarding the develop- mental processes to which wall recycling might contribute, and identify outstanding questions and emerging experimental tools that might be used to address these questions and enhance our understanding of this poorly characterized aspect of wall dynamics and metabolism.

关键词： Plant cell walls wall degradation wall recycling wall biosynthesis

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Time scales and length scales in magma ?ow pathways and the origin ofmagmatic Ni-Cu-PGE ore deposits

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Geoscience Frontiers 2019年第1期10卷 77-87页

作者： Stephen j.barnes j.sse C.Robertson CSIRO Mineral Resources

Ore forming processes involve the redistribution of heat, mass and momentum by a wide range of processes operating at different time and length scales. The fastest process at any given length scale tends to be the dominant control. Applying this principle to the array of physical processes that operate within magma flow pathways leads to some key insights into the origins of magmatic Ni-Cu-PGE sulfide ore deposits. A high proportion of mineralised systems, including those in the super-giant Noril'sk-Talnakh camp, are formed in small conduit intrusions where assimilation of country rock has played a maj.r role. Evidence of this process is reflected in the common association of sulfides with varitextured contaminated host rocks containing xenoliths in varying stages of assimilation. Direct incorporation of S-bearing country rock xenoliths is likely to be the dominant mechanism for generating sulfide liquids in this setting. However, the processes of melting or dissolving these xenoliths is relatively slow compared with magma flow rates and, depending on xenolith lithology and the composition of the carrier magma, slow compared with settling and accumulation rates. Chemical equilibration between sulfide droplets and silicate magma is slower still, as is the process of dissolving sulfide liquid into initially undersaturated silicate magmas. Much of the transport and deposition of sulfide in the carrier magmas may occur while sulfide is still incorporated in the xenoliths, accounting for the common association of magmatic sulfide-matrix ore breccias and contaminated "taxitic" host rocks. Effective upgrading of so-formed sulfide liquids would require repetitive recycling by processes such as reentrainment, back flow or gravity flow operating over the lifetime of the magma transport system as a whole. In contrast to mafic-hosted systems, komatiite-hosted ores only rarely show an association with externally-derived xenoliths, an observation which is partially due to the pre

关键词： Magmatic ore deposits Assimilation Intrusions Nickel Norilsk Komatiites

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Trap catches of the sweetpotato whitefly （Homoptera： Aleyrodidae） in the Imperial Valley, California, from 1996 to 2002

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Insect Science 2007年第2期14卷 165-170页

作者： CHANG-CHI CHU EDWARD barnes ERIC T. NATWICK TIAN-YECHEN DAVID RITTER THOMAS j. HENNEBERRY USDA ARS U.S. ALARC Maricopa Arizona E1 Centro California USA Agricultural Research Cotton Inc. Cary North Carolina E1 Centro California USA University of California Cooperative Extension DANR Holtville California E1 Centro California USA Imperial County Agricultural Commissioner' s Office E1 Centro California USA

An outbreak of the sweetpotato whitefly, Bemisia tabaci （Gennadius）, biotype B occurred in the Imperial Valley, California in 1991. The insects destroyed melon crops and seriously damaged other vegetables, ornamentals and row crops. As a result of the need for sampling technology, we developed a whitefly trap （named the CC trap） that could be left in the field for extended time periods. We used the traps to monitor populations ofB. tabaci adults during year-round samplings from 1996 to 2002 to study variations in the weekly trap catches of the insect. The greatest number ofB. tabaci adults was recorded in 1996, followed by a continuing annual decrease in trap catches each year through 2002. The overall decline of B. tabaci is attributed in part to the adoption of an integrated pest management （IPM） program initiated in 1992 and reduced melon hectares from 1996 to 2002. Other factors may also have contributed to the population reductions. Seasonally, B. tabaci trap catches decreased during the late summer and fall concurrent with decreasing minimum tempera- tares that are suggested to be a significant factor affecting seasonal activity and reproduction.

关键词： Bemisia tabaci biotype B CC trap cotton melons ornamentals

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Zircon age depth-profiling sheds light on the early Caledonian evolution of the Seve Nappe Complex in west-central j.mtland

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Geoscience Frontiers 2022年第2期13卷 460-470页

作者： Katarzyna Walczak Christopher j.barnes j.roslaw Maj.a David G.Gee Iwona Klonowska AGH University of Science and Technology Faculty of GeologyGeophysics and Environmental Protectional.Mickiewicza 3030-059 KrakówPoland Uppsala University Department of Earth SciencesVillavagen 16752-36 UppsalaSweden

The Scandinavian Caledonides comprise nappe stacks of far-travelled allochthons that record closure of the Iapetus Ocean and subsequent continental collision of Baltica and *** Seve Nappe Complex(SNC)of the Scandinavian Caledonides includes relics of the outermost Baltoscandian passive margin that were subducted to mantle *** earliest of the deep subduction events has been dated to ca.500-480 *** of this event has been reported from the northern exposures of the *** south in the central and southern segments of the SNC,(ultra)high-pressure rocks have yielded younger ages in the range of ca.470-440 *** study provides the first record of the early Caledonian event in the southern *** evidence has been obtained by depth profiling of zircon grains that were extracted from the Tv?r?klumparna microdiamond-bearing *** zircon grains preserve eclogite facies overgrowths that crystallized at 482.6±3.8 Ma.A second,chemically-distinct zircon overgrowth records granulite facies metamorphism at 439.3±3.6 Ma,which corroborates previous geochronological evidence for granulite facies metamorphism at this *** on these results,we propose that the entire outer margin of Baltica was subducted in the late Cambrian to early Ordovician,but the record of this event may be almost entirely eradicated in the vast maj.rity of lithologies by pervasive late Ordovician to early Silurian metamorphism.

关键词： Caledonian Orogeny Seve Nappe Complex Zircon geochronology Depth profiling HP/UHP metamorphism Double dunking

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A slow-growth high-mortality meta-analysis for insects： A comment on Chen and Chen

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Insect Science 2018年第2期25卷 352-354页

作者： Shannon M. Murphy Mayra C. Vidal Claudia j. Hallagan Elizabeth E. barnes E. Dale Broder Department of Biological Sciences University of Denver Denver CO US

Dear Editor, Insect Science recently published a meta-analysis that tried to test support for the slow-growth high-mortality （hereafter SG-HM） hypothesis （Chen＆ Chen, 2018）. Meta-analysis is a powerful statistical tool used to quantitatively compare and summarize multiple studies （Arnqvist ＆ Wooster, 1995）. However, results from a meta-analysis must be carefully interpreted when only limited sample sizes are available. Many conclusions made by Chen and Chen （2018） are based on low sam- rile sizes and/or have small fail-safe numbers,

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Hemodynamic improvement using methylene blue after calcium channel blocker overdose

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World j.urnal of Emergency Medicine 2019年第1期10卷 55-58页

作者： Sophia Ahmed Stacey barnes St.j.seph's Regional Medical Center

Dear editor,Calcium channel blocker overdoses are often fatal despite standard treatment. Methylene blue is a novel adj.nct that should be considered in refractory *** accepted therapeutic modalities include intraveno... 详细信息

关键词：小学英语课外阅读阅读材料

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Statistical Analysis for Engineers and Scientists：A Computer-Based Approach 工程师和科学家实用统计分析——基于计算机的方法

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2002年

作者： j. Wesley barnes

本书是第一本从现代计算机观点出发的工程统计学教材。通过集成教材中内容宽广的软件程序，结合在工程和科研中的应用，为学生讲授概率和统计学的概念。本书包含独特、全面及用户友好的软件包（用于PC机或苹果机），其特色是以应用为取... 详细信息

ISBN: (纸本)9787900641977

本书是第一本从现代计算机观点出发的工程统计学教材。通过集成教材中内容宽广的软件程序，结合在工程和科研中的应用，为学生讲授概率和统计学的概念。本书包含独特、全面及用户友好的软件包（用于PC机或苹果机），其特色是以应用为取向，而对大多数理论问题的探讨较为直观。通过精心设计的章节式学习方式和各种练习，帮助学生在充分学习使用软件的过程中掌握各章的内容，并对所有出现的假设检验中的有效样本进行了完全和详细的统计处理。本书的主要内容包括：多元回归分析、离散随机变量的卷积和变换、双变量概率分布、假设检验的操作特性曲线、统计过程控制和非参数统计分析等。

关键词： Engineering

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Reply:Is the evolution of tumors Darwinian or non-Darwinian?

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National Science Review 2018年第1期5卷 17-19页

作者： Marc j.Williams Benj.min Werner Chris P barnes Trevor A Graham Andrea Sottoriva Evolution and Cancer Laboratory Barts CancerInstitute Queen Marry University of London Department of Cell and Developmental Biology University College London Centre for Mathematics and Physics in the Life Sciences and Experimental Biology (CoMPLEX) University College London Centre for Evolution and Cancer The Institute of Cancer Research Department of Genetics Evolution and EnvironmentUniversity College London

Wu and colleagues’letter discusses the limitations of the use of a single sample per tumor to investigate neutral evolution in human *** evolution describes the situation in which there is no differential clonal selection amongst the population of cells within a cancer:all mutations thataccrue during growth are passengers and all drivers were already present in the

关键词： Reply:Is the evolution of tumors Darwinian or non-Darwinian VAF

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慢性阻塞性肺疾病的治疗前景

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中华医学杂志 2006年第41期86卷 2884-2886页

作者： Peter j.barnes 英国伦敦皇家学院国际心肺研究所

目前治疗慢性阻塞性肺疾病(COPD)的方法非常有限,尚无能够减缓病情发展和功能损伤的有效措施.因此,许多制药公司都纷纷致力于探索并研发新的、更有效的、能从根本上控制疾病进展的药物[1,2]。

关键词：慢性阻塞性肺疾病治疗前功能损伤病情发展制药公司疾病进展前治疗

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