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sc元素添加对双辊铸轧Al−Cu−Li−Mg−Zr基合金热处理的影响

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Transactions of Nonferrous Metals society of China 2024年第6期34卷 1759-1773页

作者： Rostislav KRÁLÍK barbora KŘIVsKÁ Lucia BAJTOŠOVÁ Mykhailo sTOLBCHENKO Mirko sCHAPER Olexandr GRYDIN Miroslav CIEsLAR Department of Physics of Materials Faculty of Mathematics and PhysicsCharles UniversityKe Karlovu 512116PragueCzech Republic Department of Materials science Faculty of Mechanical EngineeringUniversity of PaderbornWarburger Straße 10033098PaderbornGermany

提出制备含sc的Al−Cu−Li−Mg−Zr基合金带材的工艺方案。即先采用双辊铸轧技术制备近净形状的3 mm厚带材,再对其进行均匀化/固溶处理。研究两种Al−Cu−Li−Mg−Zr基双辊铸轧合金,其中一种添加质量分数为0.17%的sc,另一种未添加sc。两种合金... 详细信息

提出制备含sc的Al−Cu−Li−Mg−Zr基合金带材的工艺方案。即先采用双辊铸轧技术制备近净形状的3 mm厚带材,再对其进行均匀化/固溶处理。研究两种Al−Cu−Li−Mg−Zr基双辊铸轧合金,其中一种添加质量分数为0.17%的sc,另一种未添加sc。两种合金均先在300℃下退火30 min,然后在450℃下退火30 min以及530℃下退火30 min,随后进行室温水淬。前两段退火后组织中生成了细小、弥散的Al_(3)Zr/Al_(3)(sc,Zr)颗粒。最后的退火步骤起到了均匀化/固溶处理的作用。双辊铸轧材料的细小晶粒结构使含有主要合金元素的原始颗粒在较短的退火时间内溶解。缩短保温时间可以限制表面层中Li的耗尽和Al_(3)Zr/Al_(3)(sc,Zr)弥散相的明显粗化。铸态含sc材料已经具有明显细小的晶粒结构,而经均匀化/固溶处理后生成的Al_(3)(sc,Zr)弥散相抑制了晶粒在高温下发生粗化。在后续180℃下时效处理后,形成了θʹ(Al_(2)Cu)、T1(Al_(2)CuLi)和s'(Al_(2)CuMg)强化相。在峰值时效状态下,屈服强度提高了200 MPa,这一数值与类似直接冷却铸造材料的相当,从而证实了所提方案的合理性。

关键词：显微组织力学性能 Al−Cu−Li基合金 sc合金化双辊铸轧

DNA diagnostics for reliable and universal identification of Helicobacter pylori

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World Journal of Gastroenterology 2021年第41期27卷 7100-7112页

作者： Pavol sulo barbora Šipková Department of Biochemistry Comenius UniversityBratislava 84215Slovakia

Reliable diagnostics are a major challenge for the detection and treatment of Helicobacter pylori(***)*** at the forefront are non-invasive urea breath test(UBT)and stool antigen test(sAT).Polymerase chain reaction(PCR)is not endorsed due to nonspecific primers and the threat of *** specificity of DNA amplification can be achieved by nested PCR(NPCR),which involves two rounds of *** the primers are properly designed for the variable regions of the 16s rRNA gene,it is not difficult to develop an NPCR assay for the unambiguous identification of *** NPCR for a 454 bp amplicon was validated on 81 clinical biopsy,stool,and saliva samples,each from the same individuals,and compared with available *** assays,namely histology,rapid urease test,sAT,and *** assay was much more sensitive than simple PCR,and it was equally sensitive in biopsy samples as the 13CUBT test,which is considered the gold *** addition,it is sufficiently specific because sequencing of the PCR products exclusively confirmed the presence of ***-specific ***,due to the threshold and lower abundance,the sensitivity was much lower in amplifications from stool or *** detection in saliva also complicates the ability of *** to survive in the oral cavity aside from and independent of the *** reason for the lower sensitivity in stool is DNA degradation;therefore,a new NPCR assay was developed to obtain a shorter 148 bp 16s rRNA *** assay was validated on stool samples from 208 gastroenterological patients and compared to sAT ***,this NPCR revealed the presence of *** in twice the number of samples as sAT,indicating that many patients are misdiagnosed,not treated by antibiotics,and their problems are interpreted as ***,it is unclear how to properly diagnose *** in *** the first approach,sAT or UBT is *** samples are negative,the 148 bp ampl

关键词： Chronic diseases Helicobacter pylori Diagnostics Nested polymerase chain reaction DNA sequencing Detection limit

some Remarks on the Earliest Poetry of Guo Moruo （1904-12）

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Frontiers of Literary studies in China-selected Publications from Chinese Universities 2012年第4期6卷 539-552页

作者： barbora Vesterova Department of East Asian studies University of Vienna 1090 Vienna Austria

This is a study of the earliest poetry by the modern Chinese writer Guo Moruo （1892-1978）, composed between 1904 and 1912. He became famous mostly due to his ＂early poetry＂ composed in the 1920s, such as Niishen （The Goddesses）, but he was also an author of autobiographies. His autobiography shaonian shidai （Childhood） and the poems published in the volume Guo Moruo shaonian shigao （Guo Moruo＇s childhood poetry）, are analysed here in comparison with the traditional Tang poetry.

关键词： Guo Moruo earliest poetry Tang poetry qing (emotion) jing(nature)

summary of East Gondwanan Conodont Data through the Ireviken Event at Boree Creek

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Journal of Earth science 2021年第3期32卷 512-523页

作者： Andrew simpson David Mathieson Jiri Fryda barbora Frydova Archives and Collections University LibraryMacquarie UniversitySydney NSW 2109Australia Department of Biological sciences Macquarie UniversitySydney NSW 2109Australia Department of Environmental Geosciences Czech University of Life Sciences Prague16500 PragueCzech Republic

The Ireviken Event was the first Middle Paleozoic event consisting of synchronised faunal,isotopic and facies change to be *** analysis of the conodont faunas throughout the Boree Creek/Borenore Limestone succession in the central western region of the Tasman fold belt of New south Wales(Australia)revealing all five conodont zones that comprise the event is *** some zonal boundaries are precise,allowing direct comparison of stratigraphic intervals on other paleo-continents,some can only be *** data from pre-Ireviken Event strata,in contrast,only permit the identification of a broad Telychian *** identification of Wenlock post-Ireviken Event conodont zones is incomplete due to lithological variability,namely the presence of tuffaceous beds near the top of the formation and an unconformity between the Boree Creek and overlying Borenore *** Boree Creek Formation contains the only example of the Ireviken Event discovered to date from the Tasman fold belt of eastern Gondwanaland.

关键词： conodonts extinction Ireviken Event silurian Boree Creek eastern Gondwanaland

Do predator energy demands or previous exposure influence protection by aposematic coloration of prey？

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Current Zoology 2017年第3期63卷 259-267页

作者： Petr VEsELY barbora ERNEsTOVA OIdrich NEDVED Roman FUCHs Faculty of science University of South Bohemia Branisovska 1760 37005 Ceske Budejovice Czech Republic

Growing evidence exists that aposematic and toxic prey may be included in a predator's diet when the predator experiences physiological stress. The tree sparrow is known to have a significant portion of aposematic and toxic ladybirds in its natural diet. Here, we present experiments testing the attack and eating rate of the tree sparrow toward the invasive aposematic harlequin ladybird . We wondered whether the sparrow's ability to prey on native ladybirds predisposes them to also prey on harlequin ladybirds. We compared the attack and eating rates of tree sparrows of particular age and/or experience classes to test for any changes during ontogeny (hand-reared × young wild-caught ×adult wild-caught) and with differing perceived levels of physiological stress (summer adult × winter adult). Winter adult tree sparrows commonly attacked and ate the offered ladybirds with no evidence of disgust or metabolic difficulties after ingestion. Naïve and wild immature tree sparrows attacked the ladybirds but hesitated to eat them. Adult tree sparrows caught in the summer avoided attacking the ladybirds. These results suggest that tree sparrows are able to cope with chemicals ingested along with the ladybirds. This pre-adaptation enables them to include ladybirds in their diet; though they commonly do this only in times of shortage in insect availability (winter). Young sparrows showed avoidance toward the chemical protection of the ladybirds.

关键词：化学保护捕食者警戒色能源需求猎物异色瓢虫曝光树麻雀

Cytokine interplay among the diseased retina, inflammatory cells and mesenchymal stem cells-a clue to stem cell-based therapy

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World Journal of stem Cells 2019年第11期11卷 957-967页

作者： Vladimir Holan barbora Hermankova Magdalena Krulova Alena Zajicova Department of Transplantation Immunology Institute of Experimental Medicine of the Czech Academy of SciencesPrague 14220Czech Republic Department of Cell Biology Faculty of ScienceCharles UniversityPrague 12843Czech Republic

Retinal degenerative disorders,such as diabetic retinopathy,retinitis pigmentosa,age-related macular degeneration or glaucoma,represent the most common causes of loss of vision and *** spite of intensive research,treatment options to prevent,stop or cure these diseases are *** therapeutic approaches are offered by stem cell-based *** date,various types of stem cells have been evaluated in a range of *** them,mesenchymal stem/stromal cells(MsCs)derived from bone marrow or adipose tissue and used as autologous cells have been proposed to have the potential to attenuate the negative manifestations of retinal *** delivered to the vicinity of the diseased retina can exert local anti-inflammatory and repairpromoting/regenerative effects on retinal ***,MsCs also produce numerous factors that could have negative impacts on retinal *** secretory activity of MsCs is strongly influenced by the cytokine ***,the interactions among the molecules produced by the diseased retina,cytokines secreted by inflammatory cells and factors produced by MsCs will decide the development and propagation of retinal *** we discuss the interactions among cytokines and other factors in the environment of the diseased retina treated by MsCs,and we present results supporting immunoregulatory and trophic roles of molecules secreted in the vicinity of the retina during MsC-based therapy.

关键词： Retina Degenerative diseases stem cell therapy Mesenchymal stem cells Cytokines Growth factors

Non-invasive prediction of persistent villous atrophy in celiac disease

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World Journal of Gastroenterology 2020年第26期26卷 3780-3791页

作者： barbora Packova Petra Kovalcikova Zdenek Pavlovsky Daniel Bartusek Jitka Prokesova Jiri Dolina Radek Kroupa Department of Gastroenterology and Internal Medicine University Hospital BrnoFaculty of MedicineMasaryk UniversityBrno 62500Czech Republic Institute of Biostatistics and Analyses Faculty of MedicineMasaryk UniversityBrno 62500Czech Republic Department of Pathology University Hospital BrnoFaculty of MedicineMasaryk UniversityBrno 62500Czech Republic Department of Radiology and Nuclear Medicine University Hospital BrnoFaculty of MedicineMasaryk UniversityBrno 62500Czech Republic

BACKGROUND Celiac disease(CD)is an immune-mediated enteropathy that is primarily treated with a gluten-free diet(GFD).Mucosal healing is the main target of the ***,duodenal biopsy is the only way to evaluate mucosal healing,and noninvasive markers are *** elevation of anti-tissue transglutaminase antibodies(aTTG)is not an ideal predictor of persistent villous atrophy(VA).Data regarding prediction of atrophy using anti-deamidated gliadin peptide antibodies(aDGP)and abdominal ultrasonography are *** To evaluate the ability of aTTG,aDGP,small bowel ultrasonography,and clinical and laboratory parameters in predicting persistent VA determined using *** Patients with CD at least 1 year on a GFD and available follow-up duodenal biopsy,levels of aTTG and aDGP,and underwent small bowel ultrasonography were included in this retrospective cohort *** evaluated the sensitivity,specificity,and positive and negative predictive values of aTTG,aDGP,small bowel ultrasonography,laboratory and clinical parameters to predict persistent VA.A receiver operating characteristic(ROC)curve analysis of antibody levels was used to calculate cut off values with the highest accuracy for atrophy *** Complete data were available for 82 patients who were followed up over a period of four years(2014-2018).Among patients included in the analysis,women(67,81.7%)were predominant and the mean age at diagnosis was 33.8 *** biopsy revealed persistent VA in 19 patients(23.2%).The sensitivity and specificity of aTTG using the manufacturer’s diagnostic cutoff value to predict atrophy was 50%and 85.7%,respectively,while the sensitivity and specificity of aDGP(using the diagnostic cutoff value)was 77.8%and 75%,*** of an optimal cutoff value using ROC analysis(13.4 U/mL for aTTG IgA and 22.6 U/mL for aDGP IgA)increased the accuracy and reached 72.2%[95%confidence interval(CI):46.5-90.3]sensitivity and 90%(9

关键词： Celiac disease Villous atrophy Anti-tissue transglutaminase antibodies Antideamidated gliadin peptide antibodies Abdominal ultrasound Gluten-free diet

On the Issue of Commercial Insurance and Commercial Insurance Market in the slovak Republic

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Chinese Business Review 2018年第3期17卷 138-143页

作者： barbora Drugdova University of Economics in Bratislava Bratislava Slovak Republic

Limen,Non-Toxic Recombinant Plant Defensin and Its Effect against Pathogenic Yeast and Fungi

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Journal of Pharmacy and Pharmacology 2018年第11期6卷 945-955页

作者： Katerina Rehorova Jitka Viktorova barbora Macuchova Tomas Vlcko Lucie stankova Nikola Jelenova Ludmila Ohnoutkova Tomas Macek Department of Biochemistry and Microbiology University of Chemistry and TechnologyPragueTechnicka 516628Prague 6Czech Republic Department of Chemical Biology and Genetics Centre of the Region Hana for Biotechnological and Agricultural ResearchPalacky University OlomoucSlechtitelu 27Olomouc 78371Czech Republic

Limen is a small cysteine-rich peptide that was originally isolated from lima beans,and its activity against Micromycetes was *** expression of limen in both a prokaryotic and plant system was performed to demonstrate a wide selection of its activities with potential for further *** first limen was expressed in *** cells and after purification steps,its antimicrobial activity was tested on pathogenic *** showed that limen can significantly eliminate the growth of several pathogenic yeasts such as Candida albicans,while its hemolytic activity was not *** confirm limen’s activity in vivo,transformation of the barley Hordeum vulgare *** *** barley was obtained using Agrobacterium-mediated transformation and the production of limen peptide in plant tissues was verified by molecular *** barley plants were repeatedly exposed to Fusarium oxysporum *** resistance to the most important pathogen was followed using chlorophyll measurements as indicators of *** on the food safety aspect of the use of GM plants,cytotoxicity was followed in extracts from transgenic stressed *** or a lower cytotoxic effect was found on human keratinocytes and human embryonic kidney cells than extracts from the non-transformed plants.

关键词： Plant defensin recombinant production toxicity Candida Fusarium barley