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Association between helminth infections and diabetes mellitus in adults from the Lao People’s Democratic Republic:a crosssectional study

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Infectious Diseases of Poverty 2018年第1期7卷 1110-1120页

作者： Nan Shwe Nwe Htun Peter Odermatt Phimpha Paboriboune Somphou Sayasone Malisa Vongsakid Vilayouth Phimolsarn-Nusith Xuan Duong Tran Phoum-Savath Ounnavong Navalone Andriama-Hefasoa Nilun-Done Senvanpan Anousine Homsana baocher lianosay Dalouny Xayavong Dimbitsoa Rakotomalala Robinson Phaivanh Bounsavath Phoy-Phaylinh Prasayasith Seng-Davanh Syphan Yi-Xiao Lu Kanchana Thilakoun Xaipa-Song Xaiyaphet Phout-Tasin Vongngakesone Ikenna C Eze Medea Imboden Banchob Sripa Daniel Reinharz Nicole Probst-Hensch Department of Epidemiology and Public Health Swiss Tropical and Public Health InstitutePO Box40024051 BaselSwitzerland University of Basel BaselSwitzerland The Francophone Institute for Tropical Medicine(International Program for Health in the Tropics) VientianeLao PDR Lao Tropical and Public Health Institute Ministry of HealthVientianeLao People’s Democratic Republic Tropical Disease Research Laboratory Faculty of MedicineKhon Kaen UniversityKhon KaenThailand Universite Laval Quebec CityCanada

Background:As a result of epidemiological transition,the health systems of low-and middle-income countries are increasingly faced with a dual disease burden of infectious diseases and emerging non-communicable *** is known about the mutual influence of these two disease *** aim of this study was to investigate the cooccurrence of helminth infections and diabetes mellitus in adults in Lao People’s Democratic Republic(Lao PDR).Methods:We conducted a cross-sectional study among 1600 randomly selected adults aged 35 and older from four different socio-economical and ecological *** on socio-demographics,risk factors and health conditions was obtained from personal *** assessments including anthropometry(height,weight,waist and hip circumference)and blood pressure measurements were also *** was classified based on selfreported diagnoses and a point-of-care glycated haemoglobin(HbA1c)test from finger prick blood *** samples for helminth diagnosis were examined with formalin-ether concentration technique for intestinal parasitic *** independent associations of helminth infections with diabetic status and HbA1c were assessed using multiple regression ***:The prevalence of pre-diabetes and diabetes was 37.3%and 22.8%,***-six percent of diabetic cases were undiagnosed and 85%of diagnosed diabetic cases had poor glycemic *** from rural areas and from southern parts of the country had higher infection rates,with Opisthorchis viverrini,being the most common helminth infection(30.5%).We found a positive association between Taenia *** and HbA1c(β=0.117;95%CI:0.042-0.200)and diabetes mellitus risk(OR=2.98;95%CI:1.10-8.05).No other helminth species was associated with glycated ***:Hyperglycaemia and diabetic rates in Lao PDR are alarmingly high,but consistent with other high rates in the *** the high rates of unde

关键词： Dual burden of disease Opisthorchis viverrini Taenia Diabetes mellitus Cross-sectional Epidemiology Adults Lao PDR

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中药“胃粘膜保护方”对大白鼠实验性胃溃疡的预防和治疗作用的研究

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广州中医学院学报 1988年第1期 23-25页

作者：刘宝臣沈鹰广州军区广州总医院广州中医学院 58级本科毕业生

本文报告以健脾益气中药为主的“胃粘膜保护方”预防大鼠水浸应激所致的胃溃疡和治疗醋酸所致的穿透性胃溃疡的研究。结果提示该方能增强胃粘膜的防御能力和溃疡粘膜的修复能力,因而有可能为临床上治疗溃疡和预防应激性溃疡的发生提供... 详细信息

本文报告以健脾益气中药为主的“胃粘膜保护方”预防大鼠水浸应激所致的胃溃疡和治疗醋酸所致的穿透性胃溃疡的研究。结果提示该方能增强胃粘膜的防御能力和溃疡粘膜的修复能力,因而有可能为临床上治疗溃疡和预防应激性溃疡的发生提供新的途径。

关键词：胃溃疡/中医药疗法胃溃疡/预防和控制胃粘膜保护方/治疗应用疾病模型动物

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