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Hippocampal dopamine as a key regulator for learning deficits in Parkinson's disease

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Neural Regeneration Research 2024年第6期19卷 1193-1194页

作者： Kun wu Shuai Liu Shanghai Key Laboratory of Brain Functional Genomics(Ministry of Education) Affiliated Mental Health Center(ECNU)School of Psychology and Cognitive ScienceEast China Normal UniversityShanghaiChina Shanghai Changning Mental Health Center ShanghaiChina NYU-ECNU Institute of Brain and Cognitive Science at NYU Shanghai ShanghaiChina

Parkinson's disease(PD)is a progressive neurodegenerative disorder with clinical symptoms of involuntary or uncontrollable movements such as tremors,rigidity,and *** learning deficit is largely overlooked in the past ... 详细信息

关键词： impaired dopamine clinical

A level line of the Gaussian free field with measure-valued boundary conditions

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Science China Mathematics 2024年第2期67卷 367-404页

作者： Titus Lupu Hao wu Laboratoire de Probabilités Statistique et ModélisationSorbonne Universitéand UniversitéParis CitéCNRSParis F-75005France Yau Mathematical Sciences Center Tsinghua UniversityBeijing 100084China

In this article, we construct samples of Schramm-Loewner-evolution-like curves out of samples ofthe conformal loop ensemble and Poisson point processes of Brownian excursions. We show that the laws of thesecurves depend continuously on the intensity measure of the Brownian excursions. Using such a construction ofcurves, we extend the notion of level lines of the Gaussian free field to the case where the boundary conditionis measure-valued.

关键词： Schramm-Loewner evolution conformal loop ensemble Brownian excursion Gaussian free field

In Situ Reconfiguration of Assembling Pattern for Modular Continuum Robots

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Journal of Bionic Engineering 2024年第4期21卷 1695-1706页

作者： Jie Zhang Jiannan Cai Ke Ma Jinzhao Yang Zhigang wu Haijun Peng Jianing wu School of Mechanical Engineering Dalian University of TechnologyDalian116024People’s Republic of China School of Advanced Manufacturing Sun Yat-Sen UniversityShenzhen518107People’s Republic of China School of Aeronautics and Astronautics Sun Yat-Sen UniversityShenzhen518107People’s Republic of China

Modular continuum robots possess significant versatility across various scenarios;however,conventional assembling methods typically rely on linear connection between *** limitation can impede the robotic interaction capabilities,especially in specific engineering ***,inspired by the assembling pattern between the femur and tibia in a human knee,we proposed a multidirectional assembling *** strategy encompasses linear,oblique,and orthogonal connections,allowing a two-module continuum robot to undergo in-situ reconfiguration into three distinct initial *** anticipate the final configuration resulting from diverse assembling patterns,we employed the positional formulation finite element framework to establish a mechanical model,and the theoretical results reveal that our customizable strategy can offer an effective route for robotic *** showcased diverse assembling patterns for coping with interaction *** experimental results indicate that our modular continuum robot not only reconfigures its initial profile in situ but also enables on-demand regulation of the final *** capabilities provide a foundation for the future development of modular continuum robots,enabling them to be adaptable to diverse environments,particularly in unstructured surroundings.

关键词： Assembling patterns Continuum robot In-situ reconfiguration Tensegrity structure Varying stiffness

Space-time estimates of the 3D bipolar compressible Navier-Stokes-Poisson system with unequal viscosities

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Science China Mathematics 2024年第5期67卷 1059-1084页

作者： Zhigang wu Weike Wang Department of Mathematics Donghua UniversityShanghai 201620China School of Mathematical Sciences Shanghai Jiao Tong UniversityShanghai 200240China Shanghai Frontier Science Center of Modern Analysis(CMA-Shanghai) Shanghai Jiao Tong UniversityShanghai 200240China

The space-time behavior for the Cauchy problem of the 3D compressible bipolar Navier-Stokes-Poisson(BNSP)system with unequal viscosities is *** space-time estimate of the electric field▽φ=▽(-△)^(-1)(n-Zρ)is the most important in deducing generalized Huygens’principle for the BNSP system and it requires proving that the space-time estimate of n-Zρonly contains the diffusion wave due to the singularity of the operator▽(-△)^(-1).A suitable linear combination of unknowns reformulating the original system into two small subsystems for the special case(with equal viscosities)in wu and Wang(2017)is crucial for both linear analysis and nonlinear estimates,especially for the space-time estimate of▽φ.However,the benefits from this reformulation will no longer exist in general ***,we study an 8×8 Green’s matrix *** importantly,each entry in Green’s matrix contains wave operators in the low-frequency part,which will generally produce Huygens’wave;as a result,one cannot achieve the space-time estimate of n-Zρthat only contains the diffusion wave as *** overcome this difficulty by taking a more detailed spectral analysis and developing new estimates arising from subtle cancellations in Green’s function.

关键词： Green's function bipolar Navier-Stokes-Poisson system unequal viscosities

Effect of Mn addition on microstructure and mechanical properties of GX40CrNiSi25-12 austenitic heat resistant steel

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China Foundry 2024年第3期21卷 205-212页

作者： Guan-yu Jiang Meng-wu wu Xiao-guang Yang Hui Wang Yu-yuan Zhu Hubei Key Laboratory of Advanced Technology for Automotive Components Wuhan University of TechnologyWuhan 430070China Hubei Longzhong Laboratory Xiangyang 441000HubeiChina Wescast Industries(China)Co. Ltd.Wuhan 430100China

Three types of steels were designed on the basis of GX40CrNiSi25-12 austenitic heat resistant steel by adding different Mn contents(2wt.%,6wt.%,and 12wt.%).Thermodynamic calculation,microstructure characterization and mechanical property tests were conducted to investigate the effect of Mn addition on the microstructure and mechanical properties of the austenitic heat resistant *** show that the matrix structure in all the three types of steels at room temperature is completely *** NbC and M_(23)C_(6)precipitate at grain boundaries of austenite *** the increase of Mn content,the number of carbides increases and their distribution becomes more *** the Mn content increases from 1.99%to 12.06%,the ultimate tensile strength,yield strength and elongation increase by 14.6%,8.0%and 46.3%,*** improvement of the mechanical properties of austenitic steels can be explained by utilizing classic theories of alloy strengthening,including solid solution strengthening,precipitation strengthening,and grain *** increase in alloy strength can be attributed to solid solution strengthening and precipitation strengthening caused by the addition of *** improvement of the plasticity of austenitic steels can be explained from two aspects:grain refinement and homogenization of precipitated phases.

关键词： austenitic heat resistant steel manganese microstructure mechanical properties

Numerical modeling of all-day albedo variation for bifacial PV systems on rooftops and annual yield prediction in Beijing

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Building Simulation 2024年第6期17卷 955-964页

作者： Xiaoxiao Su Chenglong Luo Xinzhu Chen Jie Ji Yanshun Yu Yuandan wu wu Zou School of Energy and Power Engineering Nanjing University of Science and TechnologyNanjing210094China Department of Thermal Science and Energy Engineering University of Science and Technology of ChinaHefei230027China Institute of Energy Research Jiangxi Academy of SciencesNanchang330096China

Bifacial PV modules capture solar radiation from both sides,enhancing power generation by utilizing reflected ***,there are difficulties in obtaining ground albedo data due to its dynamic *** address this issue,this study established an experimental testing system on a rooftop and developed a model to analyze dynamic albedo variations,utilizing specific data from the *** results showed that the all-day dynamic variations in ground albedo ranged from 0.15 to 0.22 with an average of ***,this study evaluates the annual performance of a bifacial PV system in Beijing by considering the experimental conditions,utilizing bifacial modules with a front-side efficiency of 21.23%and a bifaciality factor of 0.8,and analyzing the dynamic all-day albedo data obtained from the numerical *** results indicate that the annual radiation on the rear side of bifacial PV modules is 278.90 kWh/m^(2),which accounts for only 15.50%of the front-side ***,when using the commonly default albedo value of 0.2,the rear-side radiation is 333.01 kWh/m^(2),resulting in an overestimation of 19.40%.Under dynamic albedo conditions,the bifacial system is predicted to generate an annual power output of 412.55 kWh/m^(2),representing a significant increase of approximately 12.37%compared to an idealized monofacial PV system with equivalent front-side *** a 25-year lifespan,the bifacial PV system is estimated to reduce carbon emissions by 8393.91 kgCO_(2)/m^(2),providing an additional reduction of 924.31 kgCO_(2)/m^(2)compared to the idealized monofacial PV *** findings offer valuable insights to promote the application of bifacial PV modules.

关键词： bifacial PV module ground albedo simulation carbon emission reduction

Applications of artificial intelligence to lipid nanoparticle delivery

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Particuology 2024年第7期90卷 88-97页

作者： Ye Yuan Yuqi wu Jiabei Cheng Kaiyuan Yang Yilin Xia Hongguang wu Xiaoyong Pan Institute of Image Processing and Pattern Recognition Shanghai Jiao Tong UniversityKey Laboratory of System Control and Information ProcessingMinistry of Education of ChinaChina Songjiang Research Institute Songjiang District Central HospitalShanghai Jiao Tong University School of MedicineShanghaiChina

Lipid nanoparticles(LNPs)are nanocarriers composed of four lipid components and can be used for gene therapy,protein replacement,and vaccine ***,LNPs also face several challenges,such as toxicity,immune activation,and low delivery *** overcome these challenges,artificial intelligence can be used to optimize the design and formulation of LNPs,as well as to predict their properties and ***,antibody-targeted conjugation can be used to enhance the specificity and selectivity of LNPs by attaching an antibody that recognizes a specific antigen on the cell surface to LNPs.

关键词： Artificial intelligence Lipid nanoparticles Antibody Targeted conjugation

直升机复合材料结构基于振动健康监测的研究进展

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材料导报 2020年第S1期34卷 581-584页

作者：朱洪艳吴宝昌林长亮王金亮王刚哈尔滨飞机工业集团有限责任公司哈尔滨150066

直升机纤维增强树脂基复合材料结构对冲击、疲劳应力等引起的内部分层、裂纹缺陷非常敏感,它会使复合材料结构在没有预警的情况下发生灾难性的失效。因此,对能够及时检测出复合材料内部分层损伤、裂纹方法的需求愈益急迫。而结构健康监... 详细信息

直升机纤维增强树脂基复合材料结构对冲击、疲劳应力等引起的内部分层、裂纹缺陷非常敏感,它会使复合材料结构在没有预警的情况下发生灾难性的失效。因此,对能够及时检测出复合材料内部分层损伤、裂纹方法的需求愈益急迫。而结构健康监测能够实现对复合材料结构的实时原位监测,其中基于振动的健康监测技术使用了振动特性(阻尼、模态、固有频率),它可以很容易地连续从直升机结构的振动中提取,是一种非常有应用前景的结构健康监测方法。本文综述了直升机复合材料结构基于振动特性的健康监测技术的研究进展。

关键词：复合材料直升机振动损伤健康监测

Almost Periodic Type Group Actions on Compact Quantum Metric Spaces

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Acta Mathematica Sinica,English Series 2024年第2期40卷 568-594页

作者： Bo Tao LONG Wei wu College of Mathematics MIIT Key Laboratory of Mathematical Modelling and High Performance Computing of Air VehiclesNanjing University of Aeronautics and AstronauticsNanjing 211106P.R.China School of Mathematical Sciences Shanghai Key Laboratory of Pure Mathematics and Mathematical PracticeEast China Normal UniversityShanghai 200241P.R.China

A compact quantum metric space is a complete order unit space A endowed with a Lipnorm *** give some characterizations of almost periodic type group actions on a compact quantum metric space(A,L)by means of several kinds of subsets of A,its induced equicontinuous actions on several important subsets of the dual Banach space A*,and the Lip-norm L with its induced metric space structures on the state space S(A)of A.

关键词： Lip-norm compact quantum metric space Lipschitz isomorphism almost periodicity Arzela-Ascoli theorem metric set