检索结果-南通市图书馆

Phosphorus speciation in the sediment profile of Lake Erhai, southwestern China: Fractionation and ^(31)P NMR

Journal of Environmental Sciences 2013年第6期25卷 1124-1130页

作者： Runyu Zhang Liying Wang Fengchang Wu baoan song State Key Laboratory of Environmental Geochemistry Institute of GeochemistryChinese Academy of Sciences State Environmental Protection Key Laboratory for Lake Pollution Control Chinese Research Academy of Environmental Sciences Key Laboratory of Green Pesticide and Agricultural Bioengineering Ministry of Education

The distribution characteristics of phosphorus （P） forms in the sediment profile of Lake Erhai, in southwestern China has been investigated by sequential extraction and 31p nuclear magnetic resonance spectroscopy （NMR） of NaOH extracts to understand P dynamics and its potential contribution to lake eutrophication. Contents of P fractions varied in the order of NH4C1 extracted P （NH4C1- P）〈 bicarbonate-dithionite extracted P （BD-P）〈 HC1-P, Residual-P 〈 NaOH extracted P （NaOH-P）. The highly available NH4C1-P represented less than 1% of total P （TP）. BD-P and NaOH extracted reactive P （NaOH-rP） averaged 39%, while the ratio of Fe/P was higher than 15, indicating low P release from the sediments under permanent oxic condition. The less bio-available HC1-P, NaOH extracted nonreactive P （NaOH-nrP） and residual-P contributed 61% of TP. Regression analysis revealed that BD-P, NaOH-rP and HC1-P were positively correlated with the contents of Fe and Mn, A1 and Fe, and Ca, respectively. The investigation of P compound groups in NaOH extracts by 31p NMR showed that ortho-P and monoester-P were the largest two constituents of the P pool, followed by diester-P, phosphonate and pyro-P. A comparison of vertical variations of P groups in the sediment profile suggested that these compounds were involved in the P recycling to different extents in Lake Erhai. In particular, the lake exhibits high potential for labile P release from the surface sediments, which should be taken into consideration even after the outsourced P runoff ceased.

关键词： phosphorus speciation fractionation 31p NMR sediment eutrophication

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Bactericidal bissulfone B7 targets bacterial pyruvate kinase to impair bacterial biology and pathogenicity in plants

引用

Science China(Life Sciences) 2024年第2期67卷 391-402页

作者： Awei Zhang Haizhen Zhang Ronghua Wang Hongfu He baoan song Runjiang song National Key Laboratory of Green Pesticide Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationCenter for R&D of Fine Chemicals of Guizhou UniversityGuiyang 550025China

The prevention and control of rice bacterial leaf blight(BLB)disease has not yet been achieved due to the lack of effective agrochemicals and available ***,we develop a series of novel bissulfones and a novel target with a unique mechanism to address this *** developed bissulfones can control Xanthomonas oryzae ***(Xoo),and 2-(bis(methylsulfonyl)methylene)-N-(4-chlorophenyl)hydrazine-1-carboxamide(B_(7))is more effective than the commercial drugs thiodiazole copper(TC)and bismerthiazol(BT).Pyruvate kinase(PYK)in Xoo has been identified for the first time as the target protein of our bissulfone B_(7).PYK modulates bacterial virulence via a CRP-like protein(Clp)/two-component system regulatory protein(reg R)*** elucidation of this pathway facilitates the use of B_(7)to reduce PYK expression at the transcriptional level,block PYK activity at the protein level,and impair the interaction within the PYK-Clp-reg R complex via competitive inhibition,thereby attenuating bacterial biology and *** study offers insights into the molecular and mechanistic aspects underlying anti-Xoo strategies that target *** believe that these valuable discoveries will be used for bacterial disease control in the future.

关键词： 2-bissulfone-N-phenylhydrazine-1-carboxamide derivatives Xoo antibacterial activities pyruvate kinase regulatory mechanism

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Design, Synthesis, and Antiviral Activity of Novel Chalcone Derivatives Containing a Purine Moiety

引用

Chinese Journal of Chemistry 2017年第5期35卷 665-672页

作者： Xiuhai Gan Yanjiao Wang Deyu Hu baoan song State Key Laboratory Breeding Base of Green Pestieide and Agricultural Bioengineering Key Laboratory of Green Pesticide and Agrieultural Bioengineering Ministry of Education Center for Research and Development of Fine Chemicals Guizhou University Guiyang Guizhou 550025 China College of Chemistry and Life Science Guizhou Education University Guiyang Guizhou 550018 China

To find new antiviral agents,novel chalcone derivatives containing a purine moiety were designed and synthesized by combining bioactive *** antiviral activities of the derivatives against tobacco mosaic virus （TMV） and cucumber mosaic virus （CMV） were *** showed that most of the derivatives showed antiviral *** 3n and 3p exhibited excellent curative,protective and inactivation activities against TMV,with the EC50values of 452.4,416.2,241.2 and 438.7,418.6,261.7 μg·mL-1,respectively,which were better than those of ribavirin （585.8,436.0 and 268.7 μg·mL-1）.Compounds 3n and 3p showed remarkable curative and protective activities against *** 3n showed a moderate affinity to TMV coat protein,with binding constant Ka and Kd values of 1.5 × 104 L·mol-1 and 79.8 μmol·L-1,*** findings provided an important structural insight for further designs of highly active chalcone derivatives and a basis for further study on their mechanism of action.

关键词： chalcone purine antiviral activity tobacco mosaic virus cucumber mosaic virus

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Antiviral and Antibacterial Activities of N-（4-Substituted phenyl） Acetamide Derivatives Bearing 1,3,4-Oxadiazole Moiety

引用

Chinese Journal of Chemistry 2016年第12期34卷 1236-1244页

作者： Ling Chen Peiyi Wang Zhenxing Li Lei Zhou Zhibing Wu baoan song song Yang State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering Key Laboratory of Green Pesticide and Agricultural Bioengineering Ministry of Education Center for R&D of Fine Chemicals of Guizhou University Guiyang Guizhou 550025 China College of Pharmacy East China University of Science & Technology Shanghai 550025 China

In this paper, a series of N-（4-substituted phenyl） acetamide derivatives bearing 1,3,4-oxadiazole moiety were synthesised. Preliminary bioassays revealed that these compounds not only exhibited favourable antiviral activities toward tobacco mosaic virus （TMV） but also demonstrated sustained inhibition activities against plant pathogenic bacteria, including Xanthomonas oryzae pv. oryzae, Ralstonia solanacearum, and Xanthomonas axonopodis pv. cit- ri. Among the derivatives, TC8 and TC20 exerted the strongest curative activities against TMV, with half-maximal effective concentration （EC50） values of 239.5 and 236.2μg/mL, respectively, which were comparable to that of ningnanmycin （EC50=273.2μg/mL）. Given their simple synthesis, the target compounds can serve as alternative antiviral candidates.

关键词： 1,3,4-oxadiazole acetamide synthesis antiviral antibacterial

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

[BMIM]CI Catalyzed One-Pot Synthesis of a-Aminophospho- nate Derivatives Containing a 4-Phenoxyquinazoline Moiety under Microwave Irradiation

引用

Chinese Journal of Chemistry 2011年第1期29卷 109-117页

作者： Bai, song song, baoan Bhadury, Pinaki S. Yang, song Hu, Deyu Xue, Wei Research and Development Center for Fine Chemicals Education Ministry Key Laboratory of Green Pesticide and Bioengineering Guizhou University Guiyang Guizhou 550025 China

[BMIM]Cl catalyzed three component Mannich-type reaction of 4-（quinazolin-4-yloxy）benzenamine and aldehyde with dialkyl phosphite under microwave irradiation has been described. The salient features of the reaction leading to new a-aminophosphonates include shorter reaction time and good yields. The method is environmentally friendly and does not require toxic catalysts or solvents. To the best of our knowledge, this is the first report for [BMIM]Cl induced one-pot synthesis of a-aminophosphonate derivatives.

关键词： quinazoline a-aminophosphonates [BMIM]Cl microwave chemistry multicomponent reaction

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

The first N-ligand assisted Pd catalyzed asymmetric synthesis of 3-arylsuccinimides as novel antifungal leads

引用

Organic Chemistry Frontiers 2022年第1期9卷 183-189页

作者： Jixing Lai Juan Yang Chen Yang RenéCsuk baoan song Shengkun Li Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationGuizhou UniversityHuaxi DistrictGuiyang 550025China Organic Chemistry Martin-Luther-University Halle-WittenbergKurt-Mothes-Str.2D-06120 Halle(Saale)Germany

The first palladium/chiral nitrogenous ligand-catalyzed enantioselective addition of aryl boronic acids to various maleimides was *** protocol features mild conditions combined with good functional group *** resultant 3-arylsuccinimides were shown to be novel chiral antifungal leads and inspired the discovery of novel ligands to address the challenging issues of this transformation.

关键词： catalyzed chiral palladium

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

APPLICATION AND DEVELOPMENT OF ‘GREEN’ PREVENTIVE AND CONTROL TECHNOLOGIES IN GUIZHOU TEA PLANTATIONS

引用

Frontiers of Agricultural Science and Engineering 2022年第1期9卷 75-81页

作者： Xiangyang LI Linhong JIN Zhuo CHEN baoan song State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering Key Laboratory of Green Pesticide and Agricultural BioengineeringMinistry of EducationGuizhou UniversityGuiyang 550025China

The application and development of ‘green’ preventive technologies in teaplantations is an important means of ensuring tea quality and ecologicalsafety. Ecological, agronomic and biological controls are the main preventivemeasures used in Guizhou Province. This paper summarizes the ‘green’preventive technologies being applied in Guizhou tea plantations, including theuse of plant defense inducers to regulate tea plant responses to pathogens,natural enemies to control pest species causing damage to shoots andTrifolium repens to control the main weed species. In addition, it summarizesthe integrated ‘green’ preventive technologies being used in Guizhou andprovides a foundation for the ecological maintenance of tea plantations.

关键词： ‘green’prevention natural enemies plant defense inducers tea plantations Trifolium repens

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Effects of (-)-Epigallocatechin gallate on some protein factors involved in the epidermal growth factor receptor signaling pathway

引用

Journal of Nanjing Medical University 2009年第5期23卷 293-299页

作者： Yinjiu Huang Ruiqing Xu baoan song song Yang Li Zhao Shouwei Wu Bioscience Department of Bengbu Medical College Bengbu 233030 China General Hospital of China National Offshore Oil Corp Tianjin 300452 China Key Laboratory of Green Pesticide and Bioengineering Ministry of Education Research and Development Centre for Fine Chemicals Guizhou University Guiyang 550025 China

（-）-Epigallocatechin gallate （EGCG）, a major polyphenolic constituent of green tea, can inhibit activity of specific receptor tyrosine kinases （RTKs） and related downstream signal transduction pathways, resulting in the control of unwanted cell proliferation. The epidermal growth factor receptor （EGFR） signaling pathway is one of the most important pathways that regulates growth, survival,proliferation and differentiation in mammalian cells. This review addresses the effects of EGCG on some protein factors involved in the EGFR signaling pathway in a direct or indirect manner. Based on our understanding of the interaction between EGCG and these factors, and based on their structures, EGCG could be used as a lead compound for designing and synthesizing novel drugs with significant biological activity.

关键词： (-)-Epigallocatechin gallate (EGCG) epidermal growth factor receptor (EGFR) Signaling pathway

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Synthesis, Nematicidal Activity, and 3D-QSAR of Novel 1,3,4-Oxadiazole/ Thiadiazole Thioether Derivatives

引用

Chinese Journal of Chemistry 2018年第10期36卷 939-944页

作者： Jixiang Chen Xiuhai Gan Chongfen Yi Shaobo Wang Yuyuan Yang Fangcheng He Deyu Hu baoan song State Key Laboratory Breeding Base of Green Pesticide and Agricultural Bioengineering Key Laboratory of Green Pesticide and Agricultural Bio- engineering Ministry of Education Center for Research and Develop-ment of Fine Chemicals Guizhou University Guiyang 550025 China

Forty one novel 1,3,4-oxadiazole/thiadiazole thioether derivatives containing phenoxy moiety were designed and synthesized. Bioassay demonstrated that some of them showed remarkable activities against Tylenchufus semipenetruns in vitro and in vivo. Compounds 20, 21, 35 and 39 showed excellent lethal activities after treatment for 48 h in vitro, with LC50 values of 13.4±1.8, 11.7±2.5, 13.7±2.4 and 13.31.1 mg.L-1, respectively, which were obviously superior to fosthiazate （49.1±2.8 mg.L-1） and avermectin （26.6±2.3 mg.L-1）. Compound 23. can effectively control the citrus nema- tode disease caused by T. semipenetruns at 200 mg.L-1 in vivo with （68±3）% inhibitory effect, which was even better than that of avermectin （（63±2）%）. The CoMFA and CoMSIA models of three-dimensional quantitative structure-activity relationships （3D-QSARs） were established. The compound 33 was designed based on the 3D-QSAR models with more vigorous nematicidal activities in vitro （LC50：9.8±1.4 mg.L-1） and in vivo （（70±5）%）. These results demonstrated that compound 33 can be considered as a potential nematicide.

关键词： 1,3,4-oxadiazole/thiadiazole thioether derivatives nematicidal activity cyclization structure-activity relationships molecular modeling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Enantioselective synthesis of β-amino esters bearing a quinazoline moiety via a Mannich-type reaction catalyzed by a cinchona alkaloid derivative

引用

Science China Chemistry 2013年第3期56卷 321-328页

作者： HE Ming PAN ZhaoXi BAI song LI Pei ZHANG YuPing JIN LinHong HU DeYu YANG song song baoan State Key Laboratory Breeding Base of Green Pesticides and Agricultural Bioengineering Key Laboratory of Green Pesticides and Agricultural Bioengineering Ministry of Education 3. Guizhou University

The cinchona alkaloids catalyzed the direct asymmetric Mannich reactions of 1,3-dicarbonyl compounds with acyl imines to produce novel β-amino ester derivatives containing a quinazoline *** adducts were isolated with... 详细信息

关键词： Cinchona alkaloid-based thiourea Mannich reaction β-amino esters enantioselective synthesis

来源：

同方期刊数据库评论

在线全文

同方期刊数据库

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：