检索结果-南通市图书馆

HEAT-RESISTANT COMPOSITES CURED BY ELECTRON BEAM

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Polymer Science 2001年第1期19卷 53-57页

作者： Jian-wen bao Yang Li xiang-bao chen Feng-mei Li National Key Lab of Advanced Composites Institute of Aeronautical Materials Beijing 100095 China National Key Lab of Advanced Composites Institute of Aeronautical Materials Beijing 100095 China National Key Lab of Advanced Composites Institute of Aeronautical Materials Beijing 100095 China Institute of Low Energy Nuclear Physics Beijing Normal University Beijing 100877 China

Electron beam (EB) curing of composites has many advantages. Heat-resistant EB-curing composites could substitute polyimide composites used in aeronautical engines. In this paper, the effects of catalyst and dose on the cured resin were investigated. The heat-resistance of the resin cured by EB was evaluated by dynamic mechanical analysis (DMA). The experimental results show that the mechanical properties of the composites cured by EB could meet the specifications of aeronautical engines at 250 degreesC.

关键词： electron beam curing composites epoxy heat-resistance

Role of Tenascin-X in regulating TGF-β/Smad signaling pathway in pathogenesis of slow transit constipation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2020年第7期26卷 717-724页

作者： Yi-Chao Zhang bao-xiang chen Xiao-Yu Xie Yan Zhou Qun Qian Cong-Qing Jiang Department of Colorectal and Anal Surgery of Zhongnan Hospital of Wuhan University Clinical Center of Intestinal and Colorectal Diseases of Hubei Province Hubei Key Laboratory of Intestinal and Colorectal Diseases (Zhongnan Hospital of Wuhan University) Colorectal and Anal Disease Research Center of Medical School (Zhongnan Hospital of Wuhan University) Quality Control Center of Colorectal and Anal Surgery of Health Commission of Hubei Province

BACKGROUND Chronic constipation is a gastrointestinal functional disease that seriously harms physical and mental health and impacts the quality of life of *** incidence rate is 2%-27%.Slow transit constipation(STC)is a common type of chronic functional constipation,accounting for 10.3%-45.5%of such *** have performed many studies on the pathogenesis of *** studies have indicated that the occurrence of STC may be related to multiple factors,such as dysfunction of the enteric nervous system,interstitial cells of Cajal(ICC)damage,and changes in neurotransmitters regulating intestinal *** To investigate the role of Tenascin-X(TNX)in regulating the TGF-β/Smad signaling pathway in the pathogenesis of *** This study included an experimental group and a control *** experimental group included 28 patients with severe colonic STC,and the control group included 18 patients with normal colon ***(IHC)was used to detect c-Kit,a specific marker of the *** blot,immunofluorescence,and IHC were used to detect the localization and expression of TNX and TGF-β/*** IHC showed that the number of ICC with positive c-Kit expression was significantly reduced in the colon of STC patients(22.17±3.28 vs 28.69±3.53,P0.8)and TGF-β(P<0.05,|R|=0.7).CONCLUSION The extracellular matrix protein TNX may activate the TGF-β/Smad signaling pathway by upregulat

关键词： Slow transit constipation Tenascin-X Extracellular matrix glycoproteins TGF-β

Surgical outcomes of subtotal colectomy with antiperistaltic caecorectal anastomosis vs total colectomy with ileorectal anastomosis for intractable slow-transit constipation

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Gastroenterology Report 2019年第6期7卷 449-454,I0002页

作者： Xiao-Yu Xie Kong-Liang Sun Wen-Hao chen Yan Zhou bao-xiang chen Zhao Ding Xue-Qiao Yu Yun-Hua Wu Qun Qian Cong-Qing Jiang Wei-cheng Liu Department of Colorectal and Anal Surgery Zhongnan Hospital of Wuhan UniversityWuhanHubeiP.R.China Clinical Center of Intestinal and Colorectal Diseases of Hubei Province WuhanHubeiP.R.China Key Laboratory of Intestinal and Colorectal Diseases of Hubei Province WuhanHubeiP.R.China Colorectal and Anal Disease Research Center Medical School of Wuhan UniversityWuhanHubeiP.R.China Quality Control Center of Colorectal and Anal Surgery Health Commission of Hubei ProvinceWuhanHubeiP.R.China

Background:Few studies have compared the surgical outcomes of different surgical procedures currently used to treat refractory colonic slow-transit constipation(STC),despite the increase in the number of *** study aimed to analyse the long-termsurgical outcomes of subtotal colectomy with antiperistaltic caecorectal anastomosis(SC-ACRA)vs total colectomy with ileorectal anastomosis(TC-IRA)for severe ***:Between January 2005 and January 2015,we retrospectively collected clinical data of 55 patients who underwent TC-IRA(n=35)or SC-ACRA(n=20)for severe STC at our *** post-operative functional outcomes between the two groups were ***:There were no significant differences in age(P=0.655),sex(P=0.234),period of constipation(P=0.105)and defecation frequency(P=0.698)between the TC-IRA and SC-ACRA *** a median follow-up period of 72 months(range,12–120 months),there were no significant differences between the TC-IRA and SC-ACRA groups regarding the median number of bowel movements per day[3(1/6–7)vs 3(1/6–5),P=0.578],Cleveland Clinic Florida Constipation Score[2(0–20)vs 2(0–19),P=0.454],Cleveland Clinic Incontinence Score[0(0–5)vs 0(0–2),P=0.333]and Gastrointestinal Quality of Life Index[122(81–132)vs 120(80–132),P=0.661].Moreover,there was no significant difference in the incidence of postoperative complications between the two groups(37.1%vs 25.0%,P=0.285).Conclusions:Our findings indicate that both TC-IRA and SC-ACRA are effective treatments for severe STC,with similar long-termoutcomes.

关键词： slow-transit constipation colectomy ileorectal anastomosis antiperistaltic caecorectal anastomosis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

许鞍华影片的中国新现实主义特色

艺术百家 2017年第4期33卷 72-75页

作者：倪祥保陈虹苏州大学凤凰传媒学院江苏苏州215006

许鞍华影片的新现实主义创作特色,不仅继承了中国新现实主义电影和意大利新现实主义电影的精神传统,而且富有自己的风格。其在社会底层边缘人物形象的多元化方面、主要人物形象对待自身生活命运的态度改变方面、综合自如地运用生活化和... 详细信息

许鞍华影片的新现实主义创作特色,不仅继承了中国新现实主义电影和意大利新现实主义电影的精神传统,而且富有自己的风格。其在社会底层边缘人物形象的多元化方面、主要人物形象对待自身生活命运的态度改变方面、综合自如地运用生活化和剧情化叙事方面以及将百姓日常生活与节庆文化很好融合再现生活真实方面等,都很好地服务于再现香港社会生活真实、时代发展变迁和塑造社会普通人艺术形象的任务,让观众充分感受到了她电影创作接地气的细腻及与时俱进。

关键词：电影艺术许鞍华影片中国新现实主义电影《女人四十》《天水围的日与夜》《桃姐》

Potentiating effects of L - type Ca^2＋ channel blockers on pentobarbital -induced hypnosis are influenced by serotonergic system

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

中国药理通讯 2005年第4期22卷 35-36页

作者： Xin Zhao bao - Qiong chen xiang - Yu Cui Yong - He Zhang Zhi - Bin Lin Xue - Jun Li bao -Shan Ku Department of Pharmacology Peking University School of Basic Medical Science 38 Xueyuan Lu Beijing 100083

Unraveling the therapeutic potential of Calculus Bovis in liver cancer:A novel step for targeted cancer treatment

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第3期31卷 127-129页

作者： Xing-Yu chen xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

Hepatocellular carcinoma is one of the leading causes of cancer-related deaths globally,and effective treatments are urgently *** present study aimed to investigate the inhibitory effect of Calculus Bovis(CB)on liver cancer and the underlying *** inhibited M2 tumor-associated macrophage polarization and modulated the Wnt/β-catenin signaling pathway,thereby suppressing the proliferation of liver cancer *** inhibitory effect on liver cancer growth was confirmed by both in vivo and in vitro experiments(detailed by Huang et al).The present study provides a theoretical basis for the application of CB for the treatment of liver cancer,providing new avenues for liver cancer treatment.

关键词： Calculus Bovis Liver cancer M2 tumor-associated macrophage polarization Wnt/β-catenin Pathway Tumor microenvironment

Role of iron ore in enhancing gasification of iron coke:Structural evolution,influence mechanism and kinetic analysis

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

International Journal of Minerals,Metallurgy and Materials 2025年第1期32卷 58-69页

作者： Jie Wang Wei Wang Xuheng chen Junfang bao Qiuyue Hao Heng Zheng Runsheng Xu School of Chemistry and Materials Science Hubei Engineering UniversityXiaogan 432000China Key Laboratory for Ferrous Metallurgy and Resources Utilization of Ministry of Education Wuhan University of Science and TechnologyWuhan 430081China Institue of Ironmaking Technology Baosteel Central Research InstituteShanghai 201999China State Key Laboratory of Advanced Metallurgy University of Science and Technology BeijingBeijing 100083China

The utilization of iron coke provides a green pathway for low-carbon *** uncover the influence mechanism of iron ore on the behavior and kinetics of iron coke gasification,the effect of iron ore on the microstructure of iron coke was ***,a comparative study of the gasification reactions between iron coke and coke was conducted through non-isothermal thermogravimetric *** findings indicate that compared to coke,iron coke exhibits an augmentation in micropores and specific surface area,and the micropores further extend and *** provides more adsorption sites for CO_(2) molecules during the gasification process,resulting in a reduction in the initial gasification temperature of iron *** the heating rate in non-isothermal gasification can enhance the reactivity of iron *** metallic iron reduced from iron ore is embedded in the carbon matrix,reducing the orderliness of the carbon structure,which is primarily responsible for the heightened reactivity of the carbon *** kinetic study indicates that the random pore model can effectively represent the gasification process of iron coke due to its rich pore ***,as the proportion of iron ore increases,the activation energy for the carbon gasification gradually decreases,from 246.2 kJ/mol for coke to 192.5 kJ/mol for iron coke 15wt%.

关键词： low-carbon ironmaking iron coke gasification structural evolution kinetic model

Laparoscopic liver resection utilizing the ventral avascular area of the inferior vena cava:A retrospective cohort study

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2025年第1期31卷 42-57页

作者： Kun Huang Zhu chen Heng Xiao Hai-Yang Hu Xing-Yu chen cheng-You Du xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400000China Department of General Surgery Mianyang Hospital of Traditional Chinese MedicineMianyang 621000Sichuan ProvinceChina

BACKGROUND Laparoscopic liver resection(LLR)can be challenging due to the difficulty of establishing a retrohepatic tunnel under *** the third hepatic hilum before parenchymal transection often leads to significant liver mobilization,tumor compression,and bleeding from the short hepatic veins(SHVs).This study introduces a novel technique utilizing the ventral avascular area of the inferior vena cava(IVC),allowing SHVs to be addressed after parenchymal transection,thereby reducing surgical complexity and improving outcomes in in situ *** To introduce and evaluate a novel LLR technique using the ventral avascular area of the IVC and compare its short-term outcomes with conventional *** The clinical cohort data of patients with pathologically confirmed hepatocellular carcinoma or intrahepatic cholangiocarcinoma who underwent conventional LLR and novel LLR between July 2021 and July 2023 at the First Affiliated Hospital of Chongqing Medical University were retrospectively *** novel LLR,we initially separated the caudate lobe from the IVC using dissecting forceps along the ventral avascular area of the ***,we transected the parenchyma of the left and right caudate lobes from the caudal side to the cephalic side using the avascular area as a ***,we addressed the SHVs and finally dissected the root of the right hepatic vein or left hepatic *** short-term postoperative outcomes and oncological results of the two approaches were evaluated and *** A total of 256 patients were included,with 150(58.59%)undergoing conventional LLR and 106(41.41%)undergoing novel *** novel technique resulted in significantly larger tumor resections(6.47±2.96 cm vs 4.01±2.33 cm,P<0.001),shorter operative times(199.57±60.37 minutes vs 262.33±83.90 minutes,P<0.001),less intraoperative blood loss(206.92±37.09 mL vs 363.34±131.27 mL,P<0.001),and greater resection volume(345.11±31.40 mL vs 264.38±31.98 mL,P<0.001)comp

关键词： Laparoscopic liver resection Inferior vena cava Retrohepatic tunnel Short hepatic veins Complex liver tumors Intraoperative bleeding control

Complete response of gallbladder cancer treated with gemcitabine and cisplatin chemotherapy combined with durvalumab:A case report and review of literature

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Gastrointestinal Oncology 2025年第1期17卷 226-232页

作者： Kai chen Xu Feng Yuan Shi Xin-Lin Li Zheng-Rong Shi xiang Lan Department of Hepatobiliary Surgery The First Affiliated Hospital of Chongqing Medical UniversityChongqing 400016China

BACKGROUND Gallbladder cancer(GBC)is the most common and aggressive subtype of biliary tract cancer(BTC)and has a poor prognosis.A newly developed regimen of gemcitabine,cisplatin,and durvalumab shows promise for the treatment of advanced ***,the efficacy of this treatment for GBC remains *** SUMMARY In this report,we present a case in which the triple-drug regimen exhibited marked effectiveness in treating locally advanced GBC,thus leading to a long-term survival benefit.A 68-year-old man was diagnosed with locally advanced GBC,which rendered him ineligible for curative *** three cycles of therapy,a partial response was *** one year of combined therapy,a clinical complete response was successfully *** maintenance therapy with durvalumab monotherapy resulted in a disease-free survival of 9 months for the *** patient experienced tolerable toxicities of reversible grade 2 nausea and *** adverse events were observed in the patient throughout the entirety of the *** The combination of gemcitabine and cisplatin chemotherapy with durvalumab was proven to be an effective treatment approach for advanced GBC,with manageable adverse *** research is warranted to substantiate the effectiveness of the combined regimen in the context of GBC.

关键词： Gallbladder cancer Chemotherapy Immunotherapy Durvalumab Complete response Case report