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Three-phase Enriched Environment Improves Post-stroke Gait Dysfunction via Facilitating Neuronal Plasticity in the Bilateral Sensorimotor Cortex:A Multimodal MRI/PET Analysis in Rats

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Neuroscience Bulletin 2024年第6期40卷 719-731页

作者： Yun Lu Ziyue lin Mingcong Li Yuming Zhuang Binbin Nie Jianfeng Lei Yuanyuan zhao Hui zhao School of Traditional Chinese Medicine Capital Medical UniversityBeijing100069China Beijing Key Lab of TCM Collateral Disease Theory Research Beijing100069China Beijing Engineering Research Center of Radiographic Techniques and Equipment Institute of High Energy PhysicsChinese Academy of SciencesBeijing100049China Medical Imaging Laboratory of Core Facility Center Capital Medical UniversityBeijing100069China

The three-phase Enriched Environment(EE)paradigm has been shown to promote post-stroke functional improvement,but the neuronal mechanisms are still *** this study,we applied a multimodal neuroimaging protocol combining magnetic resonance imaging(MRI)and positron emission tomography(PET)to examine the effects of post-ischemic EE treatment on structural and functional neuroplasticity in the bilateral sensorimotor *** were subjected to permanent middle cerebral artery *** motor function of the rats was examined using the DigiGait *** was applied to investigate the EE-induced structural modifications of the bilateral sensorimotor cortex.[^(18)F]-fluorodeoxyglucose PET was used to detect glucose *** oxygen level-dependent(BOLD)-functional MRI(fMRI)was used to identify the regional brain activity and functional connectivity(FC).In addition,the expression of neuroplasticity-related signaling pathways including neurotrophic factors(BDNF/CREB),axonal guidance proteins(Robo1/Slit2),and axonal growth-inhibitory proteins(NogoA/NgR)as well as downstream proteins(RhoA/ROCK)in the bilateral sensorimotor cortex were measured by Western *** results showed the three-phase EE improved the walking *** T2 mapping imaging and diffusion tensor imaging demonstrated that EE benefited structure integrity in the bilateral sensorimotor ***-MRI fused images showed improved glucose metabolism in the corresponding regions after EE ***,the BOLD-based amplitude of low-frequency fluctuations showed that EE increased spontaneous activity in the bilateral motor cortex and ipsilateral sensory *** addition,FC results showed increased sensorimotor connectivity in the ipsilateral hemisphere and increased interhemispheric motor cortical connectivity and motor cortical-thalamic connectivity following EE *** addition,a strong correlation was found between increased functional connectivity and improv

关键词： Enriched environment Gait function Neuronal plasticity Structural integrity Glucose metabolism Functional connectivity Microenvironmental molecules Axonogenesis

Ferroelectric perovskite PbTiO_(3)for advanced photocatalysis

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Rare Metals 2024年第9期43卷 4038-4055页

作者： Shuang zhao Shi-Shi Shen Lu Han Bo-Chao Tian Na Li Wei Chen Xi-bao Li School of Materials and Metallurgy University of Science and Technology LiaoningAnshan 114051China School of Materials Science and Engineering Nanchang Hangkong UniversityNanchang 330063China Department of Chemistry National University of SingaporeSingapore 117543Singapore

The ferroelectric semiconductor material PbTiO_(3)exhibits remarkable spontaneous polarization and photoelectric properties,positioning it as a promising polar *** internal electric field of ferroelectrics can separate photocarriers and enhance the catalytic performance of ***,when combined with other semiconductors,PbTiO_(3)contributes to the construction of a depolarization field,extending the catalytic applications of PbTiO_(3)***_(3)exhibits optical absorption,semiconductor,and piezoelectric *** piezoelectric polarization field enhances charge separation,modulates band structure,surface charge conduction,and heterojunction interface charge conduction,thereby amplifying photocatalytic *** paper begins by examining the structure,properties,and preparation methods of PbTiO_(3).Subsequently,it delves into the optimization of PbTiO_(3)'s structure and performance,exploring applications in photocatalysis as a ferroelectric *** is placed on the detailed discussion of surface modification,heterostructure formation,and ferroelectric polarization of PbTiO_(3)*** aspects are thoroughly explored for their role in regulating activity and optimizing the performance of photocatalysis and photopiezoelectric *** conclusion,the paper addresses the current research status of PbTiO_(3)ferroelectric materials and highlights the challenges that lie *** intention is to provide valuable references for the ongoing research in PbTiO_(3)ferroelectric materials.

关键词： PbTiO_(3) Ferroelectric polarization Photocatalysis Piezoelectric catalysis Polarization

Research progress on semi-continuous casting of magnesium alloys under external field

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China Foundry 2024年第5期21卷 516-524页

作者： Qi-yu Liao Qi-chi Le Da-zhi zhao Lei bao Tong Wang Yong-hui Jia Key Laboratory of Electromagnetic Processing of Materials Ministry of EducationNortheastern UniversityShenyang 110819China School of Materials Science and Engineering Northeastern UniversityShenyang 110819China Key Laboratory of Lightweight Structural Materials Liaoning ProvinceNortheastern UniversityShenyang 110819China Key Laboratory of Light-weight Materials Nanjing Tech UniversityNanjing 210009China

High-performance magnesium alloys are moving towards a trend of being produced on a large scale and in an integrated *** foundational key to their successful production is the high-quality cast *** alloys produced through the conventional semi-continuous casting process inevitably contain casting defects,which makes it challenging to manufacture high-quality *** integration of external field assisted controlled solidification technology,which combines physical fields such as electromagnetic and ultrasonic fields with traditional semi-continuous casting processes,enables the production of high-quality magnesium alloy ingots characterized by a homogeneous microstructure and absence of *** article mainly summarizes the technical principles of those external field assisted casting *** focus is on elaborating the refinement mechanism of different types of electromagnetic fields,ultrasonic fields,and combined physical fields during the solidification of magnesium ***,the development prospects of producing highquality magnesium alloy ingots through semi-continuous casting under the external field were discussed.

关键词： semi-continuous casting electromagnetic field ultrasonic field magnesium alloys refinement mechanism

Aerodynamic/stealth design of S-duct inlet based on discrete adjoint method

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Applied Mathematics and Mechanics(English Edition) 2024年第4期45卷 725-746页

作者： Jun DENG Ke zhao lin ZHOU Wei ZHANG Bowen SHU Jiangtao HUANG Zhenghong GAO School of Aeronautics Northwestern Polytechnical UniversityXi’an 710072China Aerospace Technology Institute of China Aerodynamic Research and Development CenterMianyang 621000Sichuan ProvinceChina

It is a major challenge for the airframe-inlet design of modern combat aircrafts,as the flow and electromagnetic wave propagation in the inlet of stealth aircraft are very *** this study,an aerodynamic/stealth optimization design method for an S-duct inlet is *** upwind scheme is introduced to the aerodynamic adjoint equation to resolve the shock wave and flow *** multilevel fast multipole algorithm(MLFMA)is utilized for the stealth adjoint equation.A dorsal S-duct inlet of flying wing layout is optimized to improve the aerodynamic and stealth *** the aerodynamic and stealth characteristics of the inlet are effectively ***,the optimization results are analyzed,and it shows that the main contradiction between aerodynamic characteristics and stealth characteristics is the centerline and crosssectional *** S-duct is smoothed,and the cross-sectional area is increased to improve the aerodynamic characteristics,while it is completely opposite for the stealth *** radar cross section(RCS)is reduced by phase cancelation for low frequency *** method is suitable for the aerodynamic/stealth design of the aircraft airframe-inlet system.

关键词： S-duct inlet aerodynamic/stealth optimization design discrete adjoint upwind scheme multilevel fast multipole algorithm(MLFMA)

Enhanced potassium storage of carbon nanofibers as binderfree anodes enabled by coupling ultra-small amorphous Sb_(2)O_(3),graphene modification and sulfur doping

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Rare Metals 2024年第1期43卷 51-64页

作者： zhao Huang Yu-Kang Lou lin Peng Yuan Peng Meng-Meng Wang Ming Zhang College of Railway Transportation Hunan University of TechnologyZhuzhou 412007China College of Semiconductors(College of Integrated Circuits) Changsha Semiconductor Technology and Application Innovation Research InstituteHunan UniversityChangsha 410082China Key Laboratory for Micro-Nano Optoelectronic Devices of Ministry of Education College of Semiconductors(College of Integrated Circuits)Hunan UniversityChangsha 410082China

Considering the intrinsic advantages of natural copiousness and cost-effectiveness of potassium resource,potassium-ion batteries(KIBs) are booming as prospective alternatives to lithium-ion batteries(LIBs) in large-scale energy storage scenarios. Nevertheless, lacking desirable electrodes for reversibly hosting the bulky K+hinders the widespread application of KIBs, and it needs to be urgently solved. Hereon, the porous S-doped Sb_(2)O_(3)-graphene-carbon(SAGC) nanofibers are manufactured through an adjustable and facile approach, which involves electrospinning, in situ etching and sulfuration. The synthesized SAGC is featured by the ultra-small amorphous Sb_(2)O_(3) homogeneously wrapped inside the carbon matrix, as well as the co-incorporation of graphene and sulfur. Tentatively,the SAGC nanofiber sheets are applied as binder-free anodes for KIBs, exhibiting a prominent cycling life(256.72 m Ah·g^(-1) over 150 cycles at 100 m A·g^(-1)) and rate·g^(-1) over 100 cycles at 1 A·g^(-1)). The positive synergy among all the active components accounts for the distinguished performances of the SAGC. By reinforcing the tolerability to the swelling stress, producing the valid electrochemical active sites, and promoting the charge transferring for reversible K+uptake, the SAGC finally renders the excellent cyclability, capacity, and rate capability. Moreover, the extrinsic electrochemical pseudocapacitance characteristics induced by the porous carbon substrate elevate the K-storage capacity of the SAGC as well. It is hoped that the conclusions drawn may offer new insights into a direction for the high-performance binderfree KIB anodes.

关键词： S-doped Sb_(2)O_(3)-graphene-carbon Nanofibers Binder-free Anodes Potassium-ion batteries

Toward a rapid and convenient nanoplastic quantification method in laboratory-scale study based on fluorescence intensity

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Frontiers of Environmental Science & Engineering 2024年第5期18卷 117-126页

作者： Ruiqi Yan Sen lin Qian Ding Lei Zhang Xia Yu Wentao zhao Qian Sui State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process School of Resources and Environmental EngineeringEast China University of Science and TechnologyShanghai200237China State Key Laboratory of Pollution Control and Resource Reuse College of Environmental Science and EngineeringTongji UniversityShanghai200092China Shanghai Institute of Pollution Control and Ecological Security Shanghai200092China

The thorough investigation of nanoplastics(NPs)in aqueous environments requires efficient and expeditious quantitative analytical methods that are sensitive to environmentally relevant NP concentrations and convenient to *** analysis-based quantitative methods have been acknowledged as effective and rapid approaches for quantifying NP concentrations in laboratory-scale ***,we compared three commonly used optical response indicators,namely fluorescence intensity(FI),ultraviolet absorbance,and turbidity,to assess their performance in quantifying ***,orthogonal experiments were conducted to evaluate the influence of various water quality parameters on the preferred indicator-based quantification *** results revealed that FI exhibits the highest correlation coefficient(>0.99)with NP ***,the limit of quantification(LOQ)for various types of NPs is exceptionally low,ranging from 0.0089 to 0.0584 mg/L in ultrapure water,well below environmentally relevant *** variations in water quality parameters such as pH,salinity,suspended solids(SS),and humic acid,a robust relationship between detectable FI and NP concentration was ***,an increased matrix,especially SS in water samples,results in an enhanced LOQ for ***,the quantitative method remains applicable in real water bodies,especially in drinking water,with NP LOQ as low as 0.0157–0.0711 mg/*** exceeds the previously reported detectable concentration for 100 nm NPs at 40µg/mL using surface-enhanced Raman *** study confirms the potential of FI as a reliable indicator for the rapid quantification of NPs in aqueous environments,offering substantial advantages in terms of both convenience and cost-effectiveness.

关键词： Nanoplastic quantification Fluorescence intensity Drinking water Limit of quantification(LOQ) Matrix effects

Tipping Point Detection Using Reservoir Computing

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Research 2024年第1期2023卷 779-790页

作者： Xin Li Qunxi Zhu Chengli zhao Xuzhe Qian Xue Zhang Xiaojun Duan Wei lin College of Science National University of Defense TechnologyChangshaHunan 410073China Research Institute of Intelligent Complex Systems and MOE Frontiers Center for Brain Science Fudan UniversityShanghai 200433China Shanghai Artificial Intelligence Laboratory Shanghai 200232China School of Mathematical Sciences SCMSSCAMand CCSBFudan UniversityShanghai 200433China

Detection in high fidelity of tipping points,the emergence of which is often induced by invisible changes in internal structures or/and external interferences,is paramountly beneficial to understanding and predicting complex dynamical systems(CDSs).Detection approaches,which have been fruitfully developed from several perspectives(e.g.,statistics,dynamics,and machine learning),have their own advantages but still encounter difficulties in the face of high-dimensional,fluctuating ***,using the reservoir computing(RC),a recently notable,resource-conserving machine learning method for reconstructing and predicting CDSs,we articulate a model-free framework to accomplish the detection only using the time series observationally recorded from the underlying unknown CDSs.

关键词： computing record ping

Ferrihydrite transformation impacted by coprecipitation of lignin:Inhibition or facilitation?

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Journal of Environmental Sciences 2024年第5期139卷 23-33页

作者： lin Liu Zhihui Yang Weichun Yang Wen Jiang Qi Liao Mengying Si Feiping zhao School of Metallurgy and Environment Central South UniversityChangsha 410083China Chinese National Engineering Research Center for Control&Treatment of Heavy Metal Pollution(CNERC-CTHMP) Changsha 410083China

Lignin is a common soil organic matter that is present in soils,but its effect on the transformation of ferrihydrite(Fh)remains *** matter is generally assumed to inhibit Fh ***,lignin can reduce Fh to Fe(Ⅱ),in which Fe(Ⅱ)-catalyzed Fh transformation ***,the effects of lignin on Fh transformation were investigated at 75℃ as a function of the lignin/Fh mass ratio(0-0.2),pH(4-8)and aging time(0-96 hr).The results of Fh-lignin samples(mass ratios=0.1)aged at different pH values showed that for Fh-lignin the time of Fh transformation into secondary crystalline minerals was significantly shortened at pH 6 when compared with pure Fh,and the Fe(Ⅱ)-accelerated transformation of Fh was strongly dependent on *** pH 6,at low lignin/Fh mass ratios(0.05-0.1),the time of secondary mineral formation decreased with increasing lignin *** high lignosulfonate-content material(lignin:Fh=0.2),Fh did not transform into secondary minerals,indicating that lignin content plays a major role in Fh *** addition,lignin affected the pathway of Fh transformation by inhibiting goethite formation and facilitating hematite *** effect of coprecipitation of lignin on Fh transformation should be useful in understanding the complex iron and carbon cycles in a soil environment.

关键词： Ferrihydrite transformation Lignin Hematite Goethite Fe(Ⅱ)-catalyzed Reactive Fe(Ⅲ)species

MADRL-based UAV swarm non-cooperative game under incomplete information

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Chinese Journal of Aeronautics 2024年第6期37卷 293-306页

作者： Ershen WANG Fan LIU Chen HONG Jing GUO lin zhao Jian XUE Ning HE School of Electronic and Information Engineering Shenyang Aerospace UniversityShenyang 110136China College of Robotics Beijing Union UniversityBeijing 100101China School of Engineering Science University of Chinese Academy of SciencesBeijing 100049China College of Smart City Beijing Union UniversityBeijing 100101China

Unmanned Aerial Vehicles(UAVs)play increasing important role in modern *** this paper,considering the incomplete observation information of individual UAV in complex combat environment,we put forward an UAV swarm non-cooperative game model based on Multi-Agent Deep Reinforcement Learning(MADRL),where the state space and action space are constructed to adapt the real features of UAV swarm air-to-air *** multi-agent particle environment is employed to generate an UAV combat scene with continuous observation *** recently popular MADRL methods are compared extensively in the UAV swarm noncooperative game model,the results indicate that the performance of Multi-Agent Soft Actor-Critic(MASAC)is better than that of other MADRL methods by a large *** swarm employing MASAC can learn more effective policies,and obtain much higher hit rate and win *** under different swarm sizes and UAV physical parameters are also performed,which implies that MASAC owns a well generalization ***,the practicability and convergence of MASAC are addressed by investigating the loss value of Q-value networks with respect to individual UAV,the results demonstrate that MASAC is of good practicability and the Nash equilibrium of the UAV swarm non-cooperative game under incomplete information can be reached.

关键词： UAV swarm Reinforcement learning Deep learning Multi-agent Non-cooperative game Nash equilibrium