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Resistance index and browning mechanism of apple peel under high temperature stress

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Horticultural Plant Journal 2024年第2期10卷 305-317页

作者： Hui Wang Shuhui Zhang Zidun Wang Dongmei Li Leiyu Yan Yifeng feng Xiaojie Liu Rongxin Chen Wenmin fan Lulong Sun Zhengyang Zhao College of Horticulture Northwest A&F UniversityYanglingShaanxi 712100China College of Horticultural Science and Engineering Shandong Agricultural University State Key Laboratory of Crop BiologyTai'anShandong 271018China

Apples are one of the most important economic crops *** of global warming and an aggravation of environmental,abnormally high temperatures occur frequently in fruit-growing season and seriously affect normal fruit growth and reduce fruit quality and *** took five-year-old Ruixue’(Qinfu 1×Pink Lady;CNA20151469.1) fruits as test materials,and the ambient temperature during fruit development was *** results showed that during the fruit-growing season,especially during the rapid growth stage (July to August),the maximum daily temperature exceeded 30℃ and lasted for more than 40 *** determine the effects of high temperature stress on the apple fruit resistance,we treated expanding,veraison,and maturity-period fruits at different *** was found that the fruits of the expanding period showed strong resistance to high temperature stress,whereas during veraison and maturity,fruit resistance to high temperature stress decreased,and the fruit peel browning phenotype ***,the content of malonaldehyde (MDA),hydrogen peroxide (H_(2)O_(2)),and superoxide anion (O._(2)^(-)) in the peel gradually increased with increasing *** content of total phenols,flavanol,and flavonoids in the peel decreased substantially at 45℃.Moreover,it was found that polyphenol oxidase gene (MdPPO1) was most sensitive to high temperature stress in ***,transient and stable MdPPO1 overexpression significantly promoted peel *** transgenic materials were more sensitive to high temperatures,and browning was more severe compared to non-genetically modified organism (WT).Stable MdPPO1 knockout calli obtained via clustered regularly interspersed short palindromic repeats (CRISPR/Cas9) gene knockout technology reduced the browning phenotype,and the resultant fruits were not sensitive to the effects of high temperature ***,MdPPO1 expression may be a key factor of high temperature-related changes observed in the browni

关键词： Malus domestica Borkh High temperature stress Peel Browning MdPPO1

Prediction of favorable geological storage areas based on sedimentary characteristics:A case study on the northeastern Ordos Basin,China

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Energy Geoscience

Energy Geoscience 2024年第4期5卷 187-197页

作者： Yue Zhao Qiang Xu Song Du Yang Zhang Tengzhuo Zhang Yinglin fan Yan Ding Sitong Song Xinxin feng General Prospecting Institute China National Administration of Coal GeologyBeijing100039China China Coal Weikun(Beijing)Energy Saving and Environmental Protection Technology Co. Ltd.Beijing102488China China University of Mining and Technology(Beijing) Beijing100083China Shaanxi Tiancheng Petroleum Technology Co. Ltd.Xi'an710000China

The Ordos Basin is a large cratonic basin with stable deposition in Northwest *** its mostly stable subsidence background and the urgent need for saline water disposal and carbon dioxide storage in the coal mining and coal chemical industries,the Ordos Basin has been chosen as a pilot demonstration site for carbon dioxide and saline water storage in ***,few studies have been made to evaluate the sedimentary and sequence stratigraphy characteristics of this region,as well as their influence on carbon dioxide and saline water storage *** address this research gap,we conducted a sedimentary study of the Lower Triassic Liujiagou Formation in the northeastern Ordos Basin utilizing the stratigraphy theory,laboratory test analysis,and pilot project demonstration,to evaluate the area's viability for the deep geological storage of gas and liquid *** studied the tectonic setting,petrological features,and sedimentary characteristics of the favorable strata and predicted favorable areas based on sequence stratigraphy *** lithology predominantly consists of feldspathic graywacke,with a fine grain size and mostly fine-to-medium-grained *** distribution of thick-grained sandstone and fine-grained sediment was identified by dividing the sequence,and a favorable reservoir-cap assemblage configuration was ***'s concluded that the Lower Triassic Liujiagou Formation exhibits suitable characteristics for the deep geological storage of carbon dioxide and saline *** study demonstrates the importance of basic theory in guiding practical applications and provides a reference for the scientific selection of favorable areas for deep basin storage.

关键词： Ordos Basin Liujiagou Formation Sedimentary facies Sequence stratigraphy Geological storage

All-optical suppression on the impact of Sun outage in laser satellite communication systems by using a nonlinear semiconductor optical amplifier

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Chinese Optics Letters 2024年第2期22卷 76-80页

作者：李晓亮刘荣科范峰 School of Electronics and Information Engineering Beihang UniversityBeijing 100191China Beijing Research Institute of Telemetry Beijing 100094China

We introduce an all-optical approach,optical parametric amplification(OPA)processor to suppress the impact of Sun outage in laser satellite communication systems,which is implemented by only one nonlinear semiconductor optical amplifier driven by both electrical and optical *** optimized OPA processor,with a current of 539 mA and a pump-to-signal ratio of 16 dB,could significantly improve the signal quality by 3.5 dB in experiments for the elevation angle of Sun radiation of 0 *** signal quality improvement is observed in the whole range of the elevation angle,confirming the effectiveness of the proposed OPA processor in the field of Sun radiation mitigation.

关键词： nonlinear optics Sun outage laser satellite communication

Bi_(2)WO_(6)/AgInS_(2)S-scheme heterojunction:Efficient photodegradation of organic pollutant and toxicity evaluation

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Journal of Materials Science & Technology 2024年第3期170卷 200-211页

作者： Yanyan Zhao Xu fan Hongxing Zheng Enzhou Liu Jun fan Xuejun Wang College of Biology Pharmacy and Food Engineering Shangluo UniversityShangluo 726000China QinLing-Bashan Mountains Bioresources Comprehensive Development C.I.C. Shaanxi University of TechnologyHanzhong 723001China School of Chemical Engineering Northwest UniversityXi’an 710069China

Constructing of heterojunction was identified as a feasible way to improve photocatalytic activity of *** this work,a n-p type Bi_(2)WO_(6)/AgInS_(2)S-scheme heterojunction was successfully prepared for organic pollutants *** Bi_(2)WO_(6)/AgInS_(2)S-scheme heterojunction exhibited much higher pho-tocatalytic activity towards Rhodamine B(92.24%,expose to visible light for 60 min),norfloxacin(81.73%,expose to visible light for 90 min)and levofloxacin(87.46%,expose to visible light for 90 min)than pure Bi_(2)WO_(6)and pure AgInS_(2).Toxicity analysis indicated the low environmental toxicity of Rhodamine B degradation intermediates for Rye seeds and Sudangrass seeds germination and *** study displayed that AgInS_(2)and Bi_(2)WO_(6)work as the primary photocatalyst to form·O_(2)−and ·OH,*** improved photocatalytic activity of the Bi_(2)WO_(6)/AgInS_(2)S-scheme heterojunction was due to the im-proved light response range and intensified carrier separation ***,a S-scheme charge transfer mechanism including multiple charge transfer channels was *** work could provide an effective strategy for organic pollutants degradation in wastewater.

关键词： Photocatalysis S-scheme heterojunction AgInS_(2) Bi_(2)WO_(6) Toxicity experiments

Developments in the study of Chinese herbal medicine's assessment index and action mechanism for diabetes mellitus

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Animal Models and Experimental Medicine 2024年第4期7卷 433-443页

作者： Xin-Yue Liu Han-Wen Zheng feng-Zhong Wang Tul-Wahab Atia Bei fan Qiong Wang Institute of Food Science and Technology Chinese Academy of Agricultural SciencesBeijingChina Sino-Portugal TCM International Cooperation Center the Affiliated Traditional Chinese Medicine Hospital of Southwest Medical UniversityLuzhouChina Dr.Panjwani Center for Molecular Medicine and Drug Research International Center for Chemical and Biological SciencesUniversity of KarachiKarachiPakistan

In traditional Chinese medicine(TCM),based on various pathogenic symptoms and the‘golden chamber’medical text,Huangdi Neijing,diabetes mellitus falls under the category‘collateral disease’.TCM,with its wealth of experience,has been treating diabetes for over two *** antidiabetic Chinese herbal medicines re-duce blood sugar,with their effective ingredients exerting unique *** well as a glucose lowering effect,TCM also regulates bodily functions to prevent diabetes associated complications,with reduced side effects compared to western synthetic *** herbal medicine is usually composed of polysaccharides,saponins,al-kaloids,flavonoids,and *** active ingredients reduce blood sugar via various mechanism of actions that include boosting endogenous insulin secretion,enhancing insulin sensitivity and adjusting key enzyme activity and scavenging free *** actions regulate glycolipid metabolism in the body,eventually achiev-ing the goal of normalizing blood *** different animal models,a number of molecular markers are available for the detection of diabetes induction and the molecular pathology of the disease is becoming ***,there is a dearth of scientific data about the pharmacology,dose-effect relationship,and structure-activity relationship of TCM and its *** research into the efficacy,toxicity and mode of action of TCM,using different metabolic and molecular markers,is key to developing novel TCM antidiabetic formulations.

关键词： animal model Chinese herbal medicine diabetes mellitus evaluation index mechanism of action

Soliton resolution and asymptotic stability of N-solutions for the defocusing Kundu–Eckhaus equation with nonzero boundary conditions

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Communications in Theoretical Physics 2024年第1期76卷 1-6页

作者： Engui fan Yanxi Zhang School of Mathematical Sciences and Key Laboratory of Mathematics for Nonlinear Science Fudan UniversityShanghai200433China Tianjin Xinhua High School No.99 machang RoadTianjin300204China

In this paper,we address interesting soliton resolution,asymptotic stability of N-soliton solutions and the Painleve asymptotics for the Kundu-Eckhaus(KE)equation with nonzero boundary conditions iq_(t)+q_(xx)-2(l|q|^(2)-1)q+4β^(2)(lql^(4)-1)q+4iβ(lql^(2))_(x)q=0,q(x,0)=q_(0)(x)-±1,x→±∞.The key to proving these results is to establish the formulation of a Riemann-Hilbert(RH)problem associated with the above Cauchy problem and find its connection with the RH problem of the defocusing NLS *** the■-steepest descent method and the results of the defocusing NLS equation,we find complete leading order approximation formulas for the defocusing KE equation on the whole(x,t)half-plane including soliton resolution and asymptotic stability of N-soliton solutions in a solitonic region,Zakharov-Shabat asymptotics in a solitonless region and the Painlevéasymptotics in two transition regions.

关键词： defocusing Kundu-Eckhaus equation Riemann-Hilbert problems steepest descent method soliton resolution asymptotic stability Painleve transcendents

Existence of Global Solutions to the Nonlocal mKdV Equation on the Line

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Chinese Annals of Mathematics,Series B 2024年第4期45卷 497-528页

作者： Anran LIU Engui fan School of Mathematical Sciences Fudan UniversityShanghai 200433China

In this paper,the authors address the existence of global solutions to the Cauchy problem for the integrable nonlocal modified Korteweg-de Vries(nonlocal mKdV for short)equation under the initial data u0∈H^(3)(R)∩H^(1,1)(R)with the L^(1)(R)small-norm assumption.A Lipschitz L2-bijection map between potential and reflection coefficient is established by using inverse scattering method based on a Riemann-Hilbert problem associated with the Cauchy *** map from initial potential to reflection coefficient is obtained in direct scattering *** inverse scattering transform goes back to the map from scattering coefficient to potential by applying the reconstruction formula and Cauchy integral *** bijective relation naturally yields the existence of global solutions in a Sobolev space H^(3)(R)∩H^(1,1)(R)to the Cauchy problem.

关键词： Nonlocal mKdV equation Riemann-Hilbert problem Plemelj projection operator Lipschitz continuous Global solutions

Vitamin D-binding protein in plasma microglia-derived extracellular vesicles as a potential biomarker for major depressive disorder

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Genes & Diseases 2024年第2期11卷 1009-1021页

作者： Gaojia Zhang Ling Li Yan Kong Dandan Xu Yu bao Zhiting Zhang Zhixiang Liao Jiao Jiao Dandan fan Xiaojing Long Ji Dai Chunming Xie Zhiqiang Meng Zhijun Zhang Department of Neurology Affiliated Zhongda HospitalResearch Institution of NeuropsychiatrySchool of MedicineSoutheast UniversityNanjingJiangsu 210009China Department of Biochemistry and Molecular Biology School of MedicineSoutheast UniversityNanjingJiangsu 210009China Shenzhen Key Laboratory of Drug Addiction Brain Cognition and Brain Disease InstituteShenzhen Institute of Advanced TechnologyChinese Academy of Sciences (CAS)ShenzhenGuangdong 518000China CAS Key Laboratory of Brain Connectome and Manipulation The Brain Cognition and Brain Disease Institute (BCBDI)Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China Lauterbur Research Center for Biomedical Imaging Shenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China Shenzhen-Hong Kong Institute of Brain Sciences-Shenzhen Fundamental Research Institutions ShenzhenGuangdong 518000China Brain Cognition and Brain Disease Institute Department of Mental Health and Public HealthFaculty of Life and Health SciencesShenzhen Institute of Advanced TechnologyChinese Academy of SciencesShenzhenGuangdong 518055China

No well-established biomarkers are available for the clinical diagnosis of major depressive disorder(MDD).Vitamin D-binding protein(VDBP)is altered in plasma and postmortem dorsolateral prefrontal cortex(DLPFC)tissues of MDD ***,the role of VDBP as a potential biomarker of MDD diagnosis was further *** extracellular vesicles(EVs)and brain cell-derived EVs(BCDEVs)were isolated from the plasma of first-episode drug-naïve or drug-free MDD patients and well-matched healthy controls(HCs)in discovery(20 MDD patients and 20 HCs)and validation cohorts(88 MDD patients and 38 HCs).VDBP level in the cerebrospinal fluid(CSF)from chronic glucocorticoid-induced depressed rhesus macaques or prelimbic cortex from lipopolysaccharide(LPS)-induced depressed mice and wild control groups was measured to evaluate its relationship with VDBP in plasma microglia-derived extracellular vesicles(MDEVs).VDBP was significantly decreased in MDD plasma MDEVs compared to HCs,and negatively correlated with HAMD-24 score with the highest diagnostic accuracy among *** in plasma MDEVs was decreased both in depressed rhesus macaques and mice.A positive correlation of VDBP in MDEVs with that in CSF was detected in depressed rhesus *** levels in prelimbic cortex microglia were negatively correlated with those in plasma MDEVs in depressed *** main results suggested that VDBP in plasma MDEVs might serve as a prospective candidate biomarker for MDD diagnosis.

关键词： Biomarker Cerebrospinal fluid Major depressive disorder Microglia derived extracellular vesicles Vitamin-D binding protein

14-bit SAR ADC with On-Chip Digital Bubble Sorting Calibration Technology

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Chinese Journal of Electronics 2024年

作者： Hua fan Zhuorui CHEN Tongrui XU Franco Maloberti Qi WEI Quanyuan feng School of Integrated Circuit Science and Engineering (Exemplary School of Microelectronics) University of Electronic Science and Technology of China (UESTC) Shenzhen Institute for Advanced Study Chongqing Institute of Microelectronics Industry Technology Department of Electrical Computer and Biomedical Engineering University of Pavia Department of Precision Instrument Tsinghua University Institute of Microelectronics Southwest Jiaotong University

This article designs a 14-bit successive approximation register analog-to-digital converter(SAR ADC).A novel digital bubble sorting calibration method is proposed and applied to eliminate the effect of capacitor mismatch on the linearity of the SAR ADC. To reduce the number of capacitors, a hybrid architecture of a high 8-bit binary-weighted capacitor array and a low 6-bit resistor array is adopted by the digital-to-analog(DAC). The common-mode voltage VCM-based switching scheme is chosen to reduce the switching energy and area of the DAC. The time-domain comparator is employed to obtain lower power consumption. Sampling is performed through a gate voltage bootstrapped switch to reduce the nonlinear errors introduced when sampling the input signal. Moreover, the SAR logic and the whole calibration is totally implemented on-chip through digital integrated circuit(IC) tools such as Design Compiler, IC compiler, etc. Finally, a prototype is designed and implemented using 0.18 μm Bipolar-complementary metal oxide semiconductor(CMOS)-double-diffused MOS 1.8 V CMOS technology. The measurement results show that the SAR ADC with on-chip bubble sorting calibration method achieves the signal-to-noise-and-distortion ratio of 69.75 dB and the spurious-free dynamic range of 83.77 dB.

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