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反射共偏移探测技术在提高煤炭采出率中的应用

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煤炭科学技术 2007年第4期35卷 34-36页

作者：杨希瑞刘志文王萍包玉霞华亭煤电股份有限公司华亭煤矿甘肃平凉744100

利用矿井物探技术的方法对工作面顶、底煤层厚度实时监测、监控,给生产部门提供准确数据,进而提高矿井煤炭的采出率。

关键词：震波技术煤层厚度采出率反射共偏移探测

原子吸收光谱法测定不同种类萝卜中微量元素镁的含量

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河北化工 2010年第10期33卷 66-67页

作者：徐慧琴于宝霞河南省轻工业学校河南郑州450006

采用原子吸收光谱法对常见几种萝卜中镁的含量进行了测定。萝卜经硝酸和高氯酸处理后,用原子吸收光谱法测定。该方法简单、快速,结果令人满意。

关键词：微量元素镁原子吸收光谱法

Dissecting the cell microenvironment of ovarian endometrioma through single-cell RNA sequencing

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Science China Life Sciences 2025年第1期68卷 116-129页

作者： Jiangpeng Wu Siyu xia Wenting Ye Yan Sun Jing Cai Fubing yu Haiping Wen Xiuwei Yi Taikang Li Mingwei Chen Jiayun Chen Ge Song Chuanbin Yang Yali Song Jigang Wang Department of Reproductive Medicine Dongguan Maternal and Child Health Care Hospital Department of Urology and Shenzhen Clinical Research Centre for GeriatricsShenzhen People's HospitalSouthern University of Science and Technology State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs Artemisinin Research Centerand Institute of Chinese Materia MedicaChina Academy of Chinese Medical Sciences Reproductive Medicine Center Foshan Women and Children Hospital State Key Laboratory of Antiviral Drugs School of PharmacyHenan University

Ovarian endometrioma（OE）, also known as “chocolate cysts,” is a cystic mass that develops in the ovaries due to endometriosis and is a common gynecological condition characterized by the growth of endometrial tissue outside the uterus, leading to symptoms such as dysmenorrhea, pelvic pain, and infertility. However, the precise molecular and cellular mechanisms driving this pathophysiology remain largely unknown, posing challenges for diagnosis and treatment. Here, we employed integrated single-cell transcriptomic profiling of over 52,000 individual cells from endometrial tissues of OE patients and healthy donors and identified twelve major cell populations. We identified notable alterations in cell type-specific proportions and molecular signatures associated with OE. Notably, the activation of IGFBP5+macrophages with pro-inflammatory properties, NK cell exhaustion, and aberrant proliferation of IQCG+and KLF2+epithelium are key features and may be the potential mechanisms underlying the pathogenesis of OE. Collectively, our data contribute to a better understanding of OE at the single cell level and may pave the way for the development of novel therapeutic strategies.

关键词： ovary high-throughput sequencing transcriptomics gene expression analysis ligand-receptor analysis

Metabolic reprogramming: a new option for the treatment of spinal cord injury

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Neural Regeneration Research 2025年第4期20卷 1042-1057页

作者： Jiangjie Chen Jinyang Chen Chao yu Kaishun xia Biao Yang Ronghao Wang Yi Li Kesi Shi yuang Zhang Haibin Xu Xuesong Zhang Jingkai Wang Qixin Chen Chengzhen Liang Department of Orthopedics The Second Affiliated Hospital of Zhejiang University School of MedicineHangzhouZhejiang ProvinceChina Orthopedics Research Institute of Zhejiang University Zhejiang UniversityHangzhouZhejiang ProvinceChina Key Laboratory of Motor System Disease Research and Precision Therapy of Zhejiang Province HangzhouZhejiang ProvinceChina Clinical Research Center of Motor System Disease of Zhejiang Province HangzhouZhejiang ProvinceChina Qiandongnan Prefecture People’s Hospital KailiGuizhou ProvinceChina Department of Orthopedics Fourth Medical CenterChinese PLA General HospitalBeijingChina

Spinal cord injuries impose a notably economic burden on society,mainly because of the severe after-effects they *** the ongoing development of various therapies for spinal cord injuries,their effectiveness remains ***,a deeper understanding of metabolism has opened up a new therapeutic opportunity in the form of metabolic *** this review,we explore the metabolic changes that occur during spinal cord injuries,their consequences,and the therapeutic tools available for metabolic *** spinal cord metabolism is characterized by independent cellular metabolism and intercellular metabolic ***,spinal cord injury results in metabolic disorders that include disturbances in glucose metabolism,lipid metabolism,and mitochondrial *** metabolic disturbances lead to corresponding pathological changes,including the failure of axonal regeneration,the accumulation of scarring,and the activation of *** rescue spinal cord injury at the metabolic level,potential metabolic reprogramming approaches have emerged,including replenishing metabolic substrates,reconstituting metabolic couplings,and targeting mitochondrial therapies to alter cell *** available evidence suggests that metabolic reprogramming holds great promise as a next-generation approach for the treatment of spinal cord *** further advance the metabolic treatment of the spinal cord injury,future efforts should focus on a deeper understanding of neurometabolism,the development of more advanced metabolomics technologies,and the design of highly effective metabolic interventions.

关键词： axons glycolysis metabolic reprogramming metabolism mitochondria neural regeneration neuroprotection oxidative phosphorylation spinal cord injury therapy

235例不同年龄段儿童传染性单核细胞增多症临床特征分析

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传染病信息 2021年第4期34卷 316-319,341页

作者：鲍玉侠毛国顺朱影阜阳市人民医院儿科 236000

目的分析不同年龄段儿童传染性单核细胞增多症(infectious mononucleosis, IM)的临床特点,为临床早期诊断及治疗提供重要依据。方法选取2018年4月-2020年3月阜阳市人民医院儿科收治的235例EBV感染所致的IM儿童作为研究对象,根据年龄分... 详细信息

目的分析不同年龄段儿童传染性单核细胞增多症(infectious mononucleosis, IM)的临床特点,为临床早期诊断及治疗提供重要依据。方法选取2018年4月-2020年3月阜阳市人民医院儿科收治的235例EBV感染所致的IM儿童作为研究对象,根据年龄分为婴幼儿组(≤3岁)、学龄前期组(4~6岁)、学龄期组(7~13岁),对3组儿童的性别分布、年龄分布、发病季节分布、临床表现、实验室检查结果和并发症等资料进行回顾性分析。结果 235例IM儿童中,发病年龄以4~6岁多见,占发病总数的46.0%;男女性别之比为1.9∶1,男性发病多见;发病季节以春夏为发病高峰,冬季发病少。各年龄组儿童临床症状以发热、咽扁桃体炎、淋巴结肿大为主,学龄期组脾脏肿大发生率、谷丙转氨酶升高率均高于婴幼儿组(P均<0.05),婴幼儿组皮疹、腹泻和合并消化系统疾病的发生率均高于其他2组(P均<0.05),学龄期组打鼾及张口呼吸发生率均高于其他2组(P均<0.05),学龄期组和学龄前期组腹痛的发生率均显著高于婴幼儿组(P均<0.05)。结论儿童IM临床表现复杂多样,一般春夏季为发病高峰期,学龄前期儿童为高发人群,婴幼儿发病也不少见。儿童IM部分临床特征和年龄相关,掌握不同年龄段儿童IM的流行病学及临床特点,对于提高儿童IM诊断与治疗效果具有重要意义。

关键词：不同年龄儿童 EB病毒传染性单核细胞增多症流行病学临床特点实验室检查分析

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茶叶中噻嗪酮残留量的气相色谱测定

分析测试学报 2001年第6期20卷 72-74页

作者：丁慧瑛朱晓雨鲍晓霞浙江出入境检验检疫局检验检疫技术中心浙江杭州310012

建立了用配有氮磷检测器 (NPD)的气相色谱仪来测定茶叶中噻嗪酮的方法 ;试样用丙酮水提取 ,正己烷反萃取 ,florisil加少量活性炭柱净化 ,以GC -NPD方式测定 ,外标法定量 ,必要时经质谱确证 ;该法准确 ,精密度好 ,杂质干扰少 ;测定限为0... 详细信息

建立了用配有氮磷检测器 (NPD)的气相色谱仪来测定茶叶中噻嗪酮的方法 ;试样用丙酮水提取 ,正己烷反萃取 ,florisil加少量活性炭柱净化 ,以GC -NPD方式测定 ,外标法定量 ,必要时经质谱确证 ;该法准确 ,精密度好 ,杂质干扰少 ;测定限为0.01×10-6(w)。

关键词：噻嗪酮茶叶气相色谱氮磷检测器测定农药残留量

Successful emergency surgical intervention in acute non-STsegment elevation myocardial infarction with rupture:A case report

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World Journal of Clinical Cases 2025年第4期13卷 41-47页

作者： Xing-Po Li Zi-Shan Wang Hong-xia yu Shan-Shan Wang Department of Cardiovascular Medicine Huantai County Hospital of Traditional Chinese MedicineZibo 256400Shandong ProvinceChina Department of Cardiovascular Medicine Zibo Hospital of Integrated Traditional Chinese and Western MedicineZibo 255500Shandong ProvinceChina

BACKGROUND The incidence of acute myocardial infarction(AMI)is rising,with cardiac rupture accounting for approximately 2%of deaths in patients with acute ST-segment elevation myocardial infarction(STEMI).Ventricular free wall rupture(FWR)occurs in approximately 2%of AMI patients and is notably rare in patients with *** of cardiac rupture include left ventricular FWR,ventricular septal rupture,and papillary muscle *** FWR usually leads to acute cardiac tamponade or electromechanical dissociation,where standard resuscitation efforts may not be *** septal rupture and papillary muscle rupture often result in refractory heart failure,with mortality rates over 50%,even with surgical or percutaneous repair *** SUMMARY We present a rare case of an acute non-STEMI patient who suffered sudden FWR causing cardiac tamponade and loss of consciousness immediate before undergoing coronary *** resuscitation and emergency open-heart repair along with coronary artery bypass grafting resulted in successful patient *** This case emphasizes the risks of AMI complications,shares a successful treatment scenario,and discusses measures to prevent such complications.

关键词： Acute non-ST segment elevation myocardial infarction Cardiac rupture Acute myocardial infarction Free wall rupture Case report

miRNA-21-5p is an important contributor to the promotion of injured peripheral nerve regeneration using hypoxia-pretreated bone marrow-derived neural crest cells

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Neural Regeneration Research 2025年第1期20卷 277-290页

作者： Meng Cong Jing-Jing Hu Yan yu xiao-Li Li xiao-Ting Sun Li-Ting Wang xia Wu Ling-Jie Zhu xiao-Jia Yang Qian-Ru He Fei Ding Hai-Yan Shi School of Medicine Nantong UniversityNantongJiangsu ProvinceChina Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education and Coinnovation Center of Neuroregeneration Nantong UniversityNantongJiangsu ProvinceChina Department of Physiology Jiangsu Health Vocational CollegeNanjingJiangsu ProvinceChina Department of Pathology Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina Jiangsu Clinical Medicine Center of Tissue Engineering and Nerve Injury Repair Affiliated Hospital of Nantong UniversityNantongJiangsu ProvinceChina

Our previous study found that rat bone marrow–derived neural crest cells(acting as Schwann cell progenitors)have the potential to promote long-distance nerve ***-based therapy can enhance peripheral nerve repair and regeneration through paracrine bioactive factors and intercellular ***,the complex contributions of various types of soluble cytokines and extracellular vesicle cargos to the secretome remain *** investigate the role of the secretome and extracellular vesicles in repairing damaged peripheral nerves,we collected conditioned culture medium from hypoxia-pretreated neural crest cells,and found that it significantly promoted the repair of sensory neurons damaged by oxygen-glucose *** mRNA expression of trophic factors was highly expressed in hypoxia-pretreated neural crest *** performed RNA sequencing and bioinformatics analysis and found that miR-21-5p was enriched in hypoxia-pretreated extracellular vesicles of neural crest ***,to further clarify the role of hypoxia-pretreated neural crest cell extracellular vesicles rich in miR-21-5p in axonal growth and regeneration of sensory neurons,we used a microfluidic axonal dissociation model of sensory neurons in vitro,and found that hypoxia-pretreated neural crest cell extracellular vesicles promoted axonal growth and regeneration of sensory neurons,which was greatly dependent on loaded ***,we constructed a miR-21-5p-loaded neural conduit to repair the sciatic nerve defect in rats and found that the motor and sensory functions of injured rat hind limb,as well as muscle tissue morphology of the hind limbs,were obviously *** findings suggest that hypoxia-pretreated neural crest extracellular vesicles are natural nanoparticles rich in ***-21-5p is one of the main contributors to promoting nerve regeneration by the neural crest cell *** helps to explain the mechanism of action of the secretome and e

关键词： axotomy cell-free therapy conditioned medium extracellular vesicles hypoxic preconditioning microRNA oxygen-glucose deprivation peripheral nerve injury Schwann cell precursors

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泪小管——泪总管吻合术的临床观察

内蒙古民族大学学报（自然科学版） 2009年第3期24卷 341-342页

作者：包玉霞张铁范王云旭通辽市科尔沁区第一人民医院内蒙古通辽028000

目的:观察外伤性泪小管断裂行泪小管——泪总管吻合术的可行性.方法:用硬膜外麻醉管作为支架,行泪小管与泪总管吻合术.结果:治愈14例(70%),好转4例(20%),无效2例(10%),总有效率90%.结论:治疗方法操作简单,方便快捷,对组织创伤小,无需特... 详细信息

目的:观察外伤性泪小管断裂行泪小管——泪总管吻合术的可行性.方法:用硬膜外麻醉管作为支架,行泪小管与泪总管吻合术.结果:治愈14例(70%),好转4例(20%),无效2例(10%),总有效率90%.结论:治疗方法操作简单,方便快捷,对组织创伤小,无需特殊的手术器械及材料,病人能接受,且手术后反应轻、并发症少.

关键词：外伤性泪小管断裂泪小管与泪总管吻合