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Human parvo-virus B19 infection among children with sickle cell anaemia in Jos,North Central Nigeria

海南医学院学报 2010年第10期16卷 1263-1265,1268页

作者： Girei AI Alao OO Joseph DE Damulak DO banwat eb Nwadioha SI Jombo GTA Department of Haematology Federal Medical CentreGombe Department of Haematology College of Health SciencesBenue State UniversityMakurdi Department of Haematology Jos University Teaching HospitalJos Department of Microbiology Jos University Teaching HospitalJos Department of Microbiology College of Health SciencesBenue State UniversityMakurdi

Objective:Human Parvovirus B19 is known to cause significant morbidity and mortality and among diverse patient population *** patients with sickle all disease,who have high red cell turn over due to chronic haemolysis,infection with parvovirus B19 can cause severe life threatening transient aplastic *** study was conducted to determine the Seroprevalence of parvovirus B19 infection and to provide basic epidemiological data on parvovirus B19 infection among children with sickle cell anaemia in Jos,north central ***: In a hospital based cross sectional survey,200 children aged 1-18 years confirmed to have sickle cell anaemia attending the paediatric sickle cell clinic of Jos university teaching hospital were studied.A questionnaire was designed to obtain basic socio-demographic information,& other relevant aspect of patients′ *** samples were taken for anti parvo-virus B19 ***: The over all prevalence rates of parvo-virus B19 immunoglobulin(IgG) and immunoglobulin(IgM) antibodies were 39.5% and 3.5% respectively,Conclusion: This study confirms that parvo-virus B19 infection is prevalent among children with sickle cell anaemia in Jos,North Central *** is a need for further studies to fully evaluate the clinical impact of the infection on our sickle cell anaemia patients.

关键词：传染病贫血病儿童红细胞

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