检索结果-南通市图书馆

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

月球上的“水”

岩石学报 2011年第2期27卷 579-588页

作者：刘扬 Lawrence A taylor Planetary Geosciences Institute Department of Earth and Planetary SciencesUniversity of Tennessee

在地球科学的各个领域中,在行星演化学和太空探索中,水都是不可缺少的元素。长久以来,我们一直认为月球是干燥的。然而最新的研究成果推翻了这个观点。近期的遥感探测和撞月实验表明,月球表面不仅含有结构水(OH和H2O),而且还有固态冰的... 详细信息

在地球科学的各个领域中,在行星演化学和太空探索中,水都是不可缺少的元素。长久以来,我们一直认为月球是干燥的。然而最新的研究成果推翻了这个观点。近期的遥感探测和撞月实验表明,月球表面不仅含有结构水(OH和H2O),而且还有固态冰的存在。对月球火山玻璃和玄武岩的磷灰石重新分析也发现了这些玻璃中的OH,揭示了月球内部有水的存在。这个发现,意味着我们可能需要重新审视现有的月球火山活动和演化的模式。月表水和内部水的存在,还为未来以月球为跳板进行太空探索,提供了重要的资源。这里,我们对月表水和内部水的研究作一总结,并就这些发现的意义展开讨论。

关键词：水月球玄武岩浆喷发演化成因

Service Restoration of Distribution Systems Under Distributed Generation Scenarios

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

CSEE Journal of Power and Energy Systems 2016年第3期2卷 43-50页

作者： Xianchao Huang Yu Yang Gareth A.taylor North China Electric Power University Beijing 102206China Huadian Electric Power Research Institute Hangzhou 310030China Brunel Institute of Power Systems Brunel UniversityUKUB83PH

A novel extended network for service restoration optimization problem under distributed generation scenarios is presented in which the main network restoration and DG island restoration problems are integrated into a unified spanning-tree *** proposed technique is aimed to realize synchronous optimization of both main network and island restorations,and thus ensure the algorithms that are used find the global optimization solution.A fast loop-breaking technique is also proposed in this *** on the circuit-branch correlation matrix,the proposed technique can break the loops in the distribution systems through matrix operations that significantly improve calculation *** results verify the correctness and advantage of the proposed algorithms:the proposed integrated optimization strategy based on the extended network has better performance compared with a two-step restoration strategy;also,the proposed loop-breaking technique has faster calculation speed compared with prim algorithm and DFS based on adjacentmatrix.

关键词： Distributed generation distribution system extended network load shedding service restoration

Integrating insulin-like growth factor 1 and sex hormones into neuroprotection:Implications for diabetes

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

World Journal of Diabetes 2017年第2期8卷 45-55页

作者： Jacob Huffman Christina Hoffmann George T taylor Behavioral Neuroscience Program Department of Psychological SciencesUniversity of MissouriSt. Interfakultare Biomedizinische Forschung-seinrichtung der Universitat Heidelberg

Brain integrity and cognitive aptitude are often impaired in patients with diabetes mellitus, presumably a result of the metabolic complications inherent to the disease. However, an increasing body of evidence has demonstrated the central role of insulin-like growth factor 1(IGF1) and its relation to sex hormones in many neuroprotective processes. Both male and female patients with diabetes display abnormal IGF1 and sexhormone levels but the comparison of these fluctuations is seldom a topic of interest. It is interesting to note that both IGF1 and sex hormones have the ability to regulate phosphoinositide 3-kinase-Akt and mitogen-activated protein kinases-extracellular signal-related kinasesignaling cascades in animal and cell culture models of neuroprotection. Additionally, there is considerable evidence demonstrating the neuroprotective coupling of IGF1 and estrogen. Androgens have also been implicated in many neuroprotective processes that operate on similar signaling cascades as the estrogen-IGF1 relation. Yet, androgens have not been directly linked to the brain IGF1 system and neuroprotection. Despite the sex-specific variations in brain integrity and hormone levels observed in diabetic patients, the IGF1-sex hormone relation in neuroprotection has yet to be fully substantiated in experimental models of diabetes. Taken together, there is a clear need for the comprehensive analysis of sex differences on brain integrity of diabetic patients and the relationship between IGF1 and sex hormones that may influence brain-health outcomes. As such, this review will briefly outline the basic relation of diabetes and IGF1 and its role in neuroprotection. We will also consider the findings on sex hormones and diabetes as a basis for separately analyzing males and females to identify possible hormone-induced brain abnormalities. Finally, we will introduce the neuroprotective interplay of IGF1 and estrogen and how androgen-derived neuroprotection operates through similar si

关键词： Diabetes Androgens Estrogen Insulin Insulin-like growth factor 1 Neuroprotection Brain integrity Cognition

Mouse models of medulloblastoma

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Chinese Journal of Cancer 2011年第7期30卷 442-449页

作者： Paul A.Northcott Sidney Croul Michael D.taylor Arthur and Sonia Labatt Brain Tumor Research Center Hospital for Sick Children

Medulloblastoma is the most common malignant pediatric brain tumor. Despite its prevalence and importance in pediatric neuro-oncology, the genes and pathways responsible for its initiation, maintenance, and progression remain poorly understood. Genetically engineered mouse models are an essential tool for uncovering the molecular and cellular basis of human diseases, including cancer, and serve a valuable role as preclinical models for testing targeted therapies. In this review, we summarize how such models have been successfully applied to the study of medulloblastoma over the past decade and what we might expect in the coming years.

关键词：小鼠模型母细胞遗传工程人类疾病脑肿瘤发病率小儿神经

Immunogenetic phenotypes in inflammatory bowel disease

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

World Journal of Gastroenterology 2006年第23期12卷 3645-3650页

作者： Maria C Dubinsky Kent taylor Stephan R Targan Jerome I Rotter Departments of Pediatrics Medicine and Medical Genetics InstituteCedars-Sinai Medical CenterLos Angeles CAUnited States

The currently accepted etiopathogenic hypothesis suggests that the chronic intestinal inflammation and related systemic manifestations characteristic of inflammatory bowel disease （IBD） are due to an overly aggressive or pathologic immune response to resident luminal bacterial constituents. Predisposing factors are genetic dysregulation of mucosal immune responses and/ or barrier function, with onset triggered by environmental stimuli. These factors and their interactions may also be important determinants of disease phenotype and disease progression. The emergence of immunogenetic phenotypes lends support to the proposed hypothesis that susceptibility genes regulate distinct immune processes, driven by luminal antigens, expressed as specific immune phenotypes which in turn influence clinical phenotypes in IBD patient.

关键词： Inflammatory bowel disease Immunereactivity Disease phenotype

Knowledge,attitude and recommendations for practice regarding dengue among the resident population of Queensland,Australia

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Asian Pacific Journal of Tropical Biomedicine 2016年第4期6卷 360-366页

作者： Narayan Gyawali Richard Stewart Bradbury Andrew William taylor-Robinson School of Medical and Applied Sciences Central Queensland University

Objective:To investigate levels of awareness of dengue among the inhabitants of Queensland(QLD),a dengue-prevalent state in the north east of ***:A computer-assisted telephone interviewing survey was conducted in mid2014.A total of 1 223 randomly selected respondents( 18 years) across QLD completed a structured questionnaire covering all aspects of ***:97.55% had heard of dengue and participated *** them,54.70% had travelled overseas(48.11% to dengue-risk countries) in the last five years.A total of94.47% said transmission is by mosquito *** addition,84.83% knew of current transmission of dengue in QLD,while 80.97% knew the focus is Far North and North ***,2.35% and 8.97% had experienced an infection in their life or that of their immediate family/partner,respectively.85.03% identified correctly at least one means of prevention.A total of 69.72% advised to use insect repellent,wear covered clothing and avoid visiting mosquito-prone areas while 20.93% advised fumigation and clearing water containers around *** was a significant difference(P 0.05).Conclusions:Although many people throughout QLD have heard of dengue,about 15%appear unaware of local transmission,its symptoms and of methods to reduce risk of infection.A lack of knowledge regarding prevention of mosquito breeding is evident in South East QLD,where dengue is not currently *** study suggests that future dengue awareness campaigns should target communities in both endemic and potentially endemic areas throughout Queensland.

关键词： Dengue Awareness Survey Transmission Prevention Queensland

Heating demand and economic feasibility analysis for year-round vegetable production in Canadian Prairies greenhouses

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Information Processing in Agriculture 2019年第1期6卷 81-90页

作者： Md Shamim Ahamed Huiqing Guo Lisa taylor Karen Tanino Department of Farm Power and Machinery Bangladesh Agricultural UniversityBangladesh Department of Mechanical Engineering University of SaskatchewanCanada Department of Plant Sciences University of SaskatchewanCanada

Greenhouse vegetable production in Canadian Prairies is important for creating a sustainable regional food economy,especially in northern *** study included the estimation of heating demand for year-round production and evaluation of the economic feasibility of greenhouse vegetable production(tomato,cucumber,and pepper)in a conceptually designed greenhouse(0.6 ha)located in remote northern communities in Saskatchewan,*** heating simulation was based on a greenhouse heating simulation model(GREENHEAT)developed by the authors *** simulation results showed that the annual heating requirement for the production of tomato,cucumber,and pepper are 1486 MJ m^2,1657 MJ m^2,and 1754 MJ m^2,*** economic analysis indicates the net return(NR)from the production of tomato,cucumber,and pepper,are C$69.2/m^2(in Canadian dollar,CAD),C$41.5/m^2,and C$43.8/m^2,respectively,based on the market price C$3.5/kg,C$2.7/kg,and C$8.0/kg,and yields of 55.0 kg m^-2,65.0 kg m^-2,and 23.0 kg m^-*** net present value(NPV)for the tomato,cucumber,and pepper production are C$1.9 M,C$1.2 M,and C$1.1 M,respectively,and the benefit-cost ratio(BCR)are 1.38,1.21,and *** economic feasibility analysis indicates the year-round production of vegetables in a greenhouse at remote northern Saskatchewan would be economically profitable.

关键词： Northern latitudes Heating requirement Economic analysis Sensitivity analysis Year-round production

Drug therapy for heart failure in older patients —what do they want？

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

Journal of Geriatric Cardiology 2015年第2期12卷 165-173页

作者： Donah Zachariah Jacqueline taylor Nigel Rowell Clare Spooner Paul R Kalra Portsmouth Hospitals NHS Trust Portsmouth P06 3L Y UK Glasgow Royal Infirmary Glasgow G40SF UK South Tees Hospitals NHS Foundation Trust TS4 3BW UK Servier Laboratories Ltd SL3 6P J UK

Chronic heart failure （CHF） is predominantly seen in older patients, and therefore real life medicine often requires the extrapolation of findings from trials conducted in much younger populations. Prescribing patterns and potential benefits in the elderly are heavily influenced by polypharmacy and co-morbid pathologies. Increasing longevity may become less relevant in the frail elderly, whereas improving quality of life （QoL） often becomes priority; the onus being on improving wellbeing, maintaining independence for longer, and delaying institution- alisation. Specific studies evaluating elderly patients with CHF are lacking and little is known regarding the tolerability and side-effect profile of evidence based drug therapies in this population. There has been recent interest on the impact of heart rate in patients with symptomatic CHF. Ivabradine, with selective heart rate lowering capabilities, is of benefit in patients with CHF and left ventricular systolic dysfunction in sinus rhythm, resulting in reduction of heart failure hospitalisation and cardiovascular death. This manuscript will focus on CHF and the older patient and will discuss the impact of heart rate, drug therapies and tolerability. It will also highlight the tmmet need for specific studies that focus on patient-centred study end points rather than mortality targets that characterise most therapeutic trials. An on-going study evalu- ating the impact of ivabradine on QoL that presents a unique opportunity to evaluate the tolerability and impact of an established therapy on a wide range of real life, older patients with CHF will be discussed.

关键词： Heart failure Heart rate Quality of life The elderly

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

以超声振动原理模拟滑动轴承的气蚀磨损

摩擦学学报 2001年第3期21卷 232-234页

作者：安琦 taylor CM 华东理工大学机械学院上海200237 School of Mechanical Engineering University of Leeds

采用超声振动原理建立了滑动轴承气蚀磨损模拟试验装置 ,并用该试验装置研究了滑动轴承气蚀磨损现象 .通过分析比较大量实验研究结果 ,发现了一些新的气蚀现象 ,并对滑动轴承气蚀机理进行了分析 .

关键词：超声振动原理滑动轴承气蚀磨损模拟试验装置