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Journal of Iron and Steel Research International 2020年第1期27卷 62-74页

作者： Joong-ki Hwang sung Jin kim School of Mechanical Engineering Tongmyong UniversityBusan 48520Republic of Korea Department of Advanced Materials Engineering Sunchon National UniversitySuncheon 57922Republic of Korea

The effects of reduction in area(RA)per pass during caliber rolling on microstructure and strain distribution of twinninginduced plasticity steel have been investigated to find solutions to make a more homogeneous material along the radial direction for wire rod *** steel wires subjected to an average RA per pass of 2.5%(skin pass caliber rolling)and 10.0%(conventional caliber rolling)were *** skin pass caliber-rolled wire was characterized as a duplex fiber texture of majorand minor.and the textures were almost same at/between center and surface area,which is totally different from those of conventional caliber rolling and wire *** skin pass caliber rolling led to more homogeneous microstructure and mechanical properties along the radial direction in comparison with the conventional caliber rolling and wire drawing due to the more homogeneous Hall-Petch hardening,dislocation hardening,and texture behavior with area,resulting in higher formability.

关键词： Twinning-induced plasticity steel Caliber rolling Deformation twin Reduction in area Skin pass

Management of antiviral drug resistance in chronic hepatitis B

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World Journal of Gastroenterology 2014年第33期20卷 11641-11649页

作者： ki Bae bang Hong Joo kim Department of Internal Medicine Sungkyunkwan University Kangbuk Samsung Hospital Seoul 110-746 South Korea

Rescue antiviral treatment for patients with resistance to preexisting nucleos(t)ide analogues remains a clinical challenge. The correct choice of a first-line treatment of high potency and with a high genetic barrier to achieve sustained long-term suppression of viral replication provides the best chance of preventing treatment failure and the emergence of drug resistance. The management of treatment failure and drug resistance requires a precise and accurate clinical and virologic monitoring. Combination treatment with antiviral drugs that belong to different groups is associated with a lower chance of developing resistance to rescue drugs. To guarantee better control of viral replication in patients with drug resistance, the addition of another drug without a cross resistance profile should be given as early as possible, preferably at the time when genotypic resistance emerges. Long-term surveillance for treatment efficacy and possible emergence of drug resistance should be continued to prevent the emergence of multidrug-resistant strains.

关键词： Chronic hepatitis B Antiviral resistance Rescue treatment Multidrug resistance Cross resistance

Role of milk carbohydrates in intestinal health of nursery pigs: a review

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Journal of Animal Science and Biotechnology 2022年第3期13卷 628-641页

作者： ki Beom Jang sung Woo kim Department of Animal Science North Carolina State UniversityRaleighNC 27695USA

Intestinal health is essential for the resistance to enteric diseases and for nutrient digestion and absorption to support *** intestine of nursery pigs are immature and vulnerable to external challenges,which cause negative impacts on the structure and function of the *** nutritional interventions,the benefits of milk are significant for the intestinal health of *** coproducts have traditionally been used in starter feeds to improve the growth of nursery pigs,but their use is somewhat limited due to the high costs and potential risks of excessive lactose on the ***,understanding a proper feeding level of milk carbohydrates is an important start of the feeding *** nursery pigs,lactose is considered a highly digestible energy source compared with plant-based starch,whereas milk oligosaccharides are considered bioactive compounds modulating intestinal immunity and ***,milk carbohydrates,mainly composed of lactose and oligosaccharides,have essential roles in the intestinal development and functions of nursery *** proper feeding levels of lactose in starter feeds could be variable by weaning age,body weight,or genetic *** of lactose and milk oligosaccharides have been broadly studied in human health and animal ***,this review focuses on the mechanisms of lactose and milk oligosaccharides affecting intestinal maturation and functions through modulation of enterocyte proliferation,intestinal immunity,and intestinal microbiota of nursery pigs.

关键词： Intestinal health Lactose Milk carbohydrates Milk oligosaccharides Nursery pig

Optimal allocation of random access period for wireless body area network

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Journal of Central South University 2013年第8期20卷 2195-2201页

作者： Jin hyuk kiM Chang ki HONG Sang bang CHOI Department of Electronic Engineering Inha University

A wireless body area network (WBAN) allows integration of low power, invasive or noninvasive miniaturized sensors around a human body. WBAN is expected to become a basic infrastructure element for human health monitoring. The Task Group 6 of IEEE 802.15 is formed to address specific needs of body area network. It defines a medium access control layer that supports various physical layers. In this work, we analyze the efficiency of simple slotted ALOHA scheme, and then propose a novel allocation scheme that controls the random access period and packet transmission probability to optimize channel efficiency. NS-2 simulations have been carried out to evaluate its performance. The simulation results demonstrate significant performance improvement in latency and throughput using the proposed MAC algorithm.

关键词： wireless body area network channel efficiency quality of service low latency

Prospective comparison of prophylactic antibiotic use between intravenous moxifloxacin and ceftriaxone for high-risk patients with post-ERCP cholangitis

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Hepatobiliary & Pancreatic Diseases International 2017年第5期16卷 512-518页

作者： Nam Hee kim Hong Joo kim ki Bae bang Department of Internal Medicine Sungkyunkwan University Kangbuk Samsung Hospital Department of Internal Medicine Dankook University Hospital

BACKGROUND: The use of prophylactic antibiotics before endoscopic retrograde cholangiopancreatography(ERCP) is recommended by all major international gastroenterological societies, especially in the presence of an obstructed biliary system. This study compared the occurrence rate of post-procedural complications, including cholangitis and septicemia between prophylactic intravenous moxifloxacin and ceftriaxone in patients with bile duct obstruction scheduled for therapeutic ***: From November 2013 to July 2015, 86 consecutive patients with biliary obstruction with one or more factors predicting benefits of antibiotic prophylaxis prior to ERCP were included in the current randomized open-label non-inferiority trial(Clinical *** identifier NCT02098486). Intravenous moxifloxacin(400 mg/day) or ceftriaxone(2 g/day)were given 90 minutes before ERCP, and were administered for more than 3 days if the patient developed symptoms and signs of cholangitis or septicemia. Recalcitrant cholangitis was defined as persistence of cholangitis for more than 5 days after ERCP or recurrence of cholangitis within 30 days after ***: Recalcitrant cholangitis occurred in 1(2.3%) and 2(4.8%) patients receiving intravenous moxifloxacin and ceftriaxone group, respectively(P=0.612). Septicemia was noted in1(2.3%) and 1(2.4%) patient in intravenous moxifloxacin and ceftriaxone group, respectively(P=1.0). The mean hospital stay was also not significantly different between the moxifloxacin and ceftriaxone groups(8.8±7.2 vs 9.1±9.4 days, P=0.867). Antibiotic resistance of the isolated pathogens by in vitro activity assay was noted in 1(2.3%) and 2(4.8%) patients in the moxifloxacin and ceftriaxone group, respectively(P=0.612). CONCLUSION: Intravenous moxifloxacin is not inferior to intravenous ceftriaxone for the prophylactic treatment of post-ERCP cholangitis and cholangitis-associated morbidity.

关键词： endoscopic retrograde cholangiopancreatography cholangitis moxifloxacin ceftriaxone recalcitrant cholangitis

Flexible Memristive Devices Based on Graphene Quantum-Dot Nanocomposites

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Computers, Materials & Continua 2022年第8期72卷 3283-3297页

作者： sung Won Hwang Dae-ki Hong Department of System Semiconductor Engineering SangMyung UniversityCheonan-si31066Korea

Artificial neural networks(ANNs)are attracting attention for their high performance in various fields,because increasing the network size improves its *** large-scale neural networks are difficult to implement on custom hardware,a two-dimensional(2D)structure is applied to an ANN in the form of a *** demonstrate a synapse crossbar device from recent research by applying a memristive system to neuromorphic *** system is designed using two-dimensional structures,graphene quantum dots(GQDs)and graphene oxide(GO).Raman spectrum analysis results indicate a D-band of 1421 cm^(−1) that occurs in the disorder;band is expressed as an atomic characteristic of carbon in the sp2 hybridized *** is also a G-band of 1518 cm^(−1) that corresponds to the graphite *** G bands measured for RGO-GQDs present significant GQD edge-dependent shifts with *** avoid an abruptly-formed conduction path,effect of barrier layer on graphene/ITO interface was *** confirmed the variation in the nanostructure in the RGO-GQD layers by analyzing them using *** applying a negative bias to the electrode,a crystalline RGO-GQD region formed,which a conductive ***,a synaptic array for a neuromorphic chip with GQDs applied was demonstrated using a crossbar array.

关键词： Memristive devices neuromorphic chip resistive RAM quantum dot graphene

Performance Evaluation of Composite Electrolyte with GQD for All-Solid-State Lithium Batteries

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Computers, Materials & Continua 2023年第1期74卷 55-66页

作者： sung Won Hwang Dae-ki Hong Department of System Semiconductor Engineering SangMyung UniversityCheonan-si31066Korea

The use a stabilized lithium structure as cathode material for batteries could be a fundamental alternative in the development of next-generation energy storage ***,the lithium structure severely limits battery life causes safety concerns due to the growth of lithium(Li)dendrites during rapid charge/discharge *** electrolytes,which are used in highdensity energy storage devices and avoid the instability of liquid electrolytes,can be a promising alternative for next-generation ***,poor lithium ion conductivity and structural defects at room temperature have been pointed out as *** this study,through the application of a low-dimensional graphene quantum dot(GQD)layer structure,stable operation characteristics were demonstrated based on Li^(+)ion conductivity and excellent electrochemical ***,the device based on the modified graphene quantum dots(GQDs)in solid state exhibited retention properties of 95.3%for 100 cycles at 0.5 C and room temperature(RT).Transmission electronmicroscopy analysis was performed to elucidate the Li^(+)ion action mechanism in the modified GQD/electrolyte *** low-dimensional structure of theGQD-based solid electrolyte has provided an important strategy for stably-scalable solid-state lithium battery applications at room *** was demonstrated that lithiated graphene quantum dots(Li-GQDs)inhibit the growth of Li dendrites by regulating the modified Li^(+)ion flux during charge/discharge cycling at current densities of 2.2–5.5 mA cm,acting as a modified Li diffusion heterointerface.A full Li GQDbased device was fabricated to demonstrate the practicality of the modified Li structure using the Li–GQD *** study indicates that the low-dimensional carbon structure in Li–GQDs can be an effective approach for stabilization of solid-state Li matrix architecture.

关键词： Solid-state lithium batteries composite electrolyte quantum dot graphene

Learning models for endoscopic ultrasonography in gastrointestinal endoscopy

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World Journal of Gastroenterology 2015年第17期21卷 5176-5182页

作者： Gwang Ha kim sung Jo bang Joo Ha Hwang Department of Internal Medicine Pusan National University School of Medicine Biomedical Research Institute Pusan National University HospitalBusan 602-739South Korea Department of Internal Medicine Ulsan University Hospital University of Ulsan College of Medicine Ulsan 682-714South Korea Division of Gastroenterology Department of MedicineUniversity of WashingtonSeattleWA 98104United States

Endoscopic ultrasonography(EUS) has become a useful diagnostic and therapeutic modality in gastrointestinal ***,EUS requires additional training since it requires simultaneous endoscopic manipulation and ultrasonographic *** adequate EUS training can be challenging since EUS is highly operator-dependent and training on actual patients can be associated with an increased risk of complications including inaccurate ***,several models have been developed to help facilitate training of *** models currently available for EUS training include computer-based simulators,phantoms,ex vivo models,and live animal *** each model has its own merits and limitations,the value of these different models is rather complementary than ***,there is a lack of objective data regarding the efficacy of each model with recommendations on the use of various training models based on expert opinion ***,objective studies evaluating the efficacy of various EUS training models on technical and clinical outcomes are still needed.

关键词： Endoscopic ultrasonography Training Phantom Computer simulation Animal model

Aging Analysis Framework of Windows-Based Systems through Differential-Analysis of System Snapshots

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Computers, Materials & Continua 2022年第12期73卷 5091-5102页

作者： Eun-Tae Jang sung Hoon Baek ki-Woong Park SysCore Lab Sejong UniversitySeoul05006Korea Department of Computer System Engineering Jungwon UniversityChungcheongbuk-do28024Korea

When aWindows-based system is used for an exceedingly long time,its performance degrades,and the error occurrence rate tends to *** is generally called system *** investigate the reasons for system aging,various studies have been conducted within the range of the operating system kernel to the user ***,finding an accurate reason for system performance degradation remains challenging research *** this study,system monitoring was conducted by dividing a system into‘before software installation,’‘after software installation,’and‘after software removal.’We confirmed that when a software installed in a system is removed,various system elements,such as storage and memory,are not restored to the level prior to the software ***,we established a hypothesis regarding the performance degradation of a computer system owing to repeated software installation/removal operations,investigated the correlation between system aging and repeated software installation/removal operations,and proposed a system aging analysis framework for analyzing the reason behind system *** the proposed system aging analysis framework,we aim to forcibly age a Windows-based system by repeating the software installation/removal operation by utilizing the system forced aging *** framework identifies the elements affecting system performance through a differential data analysis of the system time-series data extracted by the system performance extraction and system component snapshot ***,the aging analysis framework presented in this study is expected to be effectively utilized as an index for studying system aging.

关键词： System aging virtual machine system analysis