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Reduce Training Error of Extreme Learning Machine by Selecting Appropriate Hidden Layer Output Matrix

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Journal of Systems Science and Systems Engineering 2021年第5期30卷 552-571页

作者： Yang Lv bang li Jinghu Yu Yiming Ding School of Science Wuhan University of TechnologyWuhan 430070China Center for Mathematical Sciences Wuhan University of TechnologyWuhan 430070China

Extreme learning machine(ELM)is a feedforward neural network with a single layer of hidden nodes,where the weight and the bias connecting input to hidden nodes are randomly *** output weight between hidden nodes and outputs are learned by a linear *** is interesting to ask whether the training error of ELM is significantly affected by the hidden layer output matrix H,because a positive answer will enable us obtain smaller training error from better *** single hidden layer feedforward neural network(SLFN)with one input neuron,there is significant difference between the training errors of different *** find there is a reliable strong negative rank correlation between the training errors and some singular values of the Moore-Penrose generalized inverse of *** on the rank correlation,a selection algorithm is proposed to choose robust appropriate H to achieve smaller training error among numerous *** experiments are carried out to validate the selection algorithm,including tests on real data *** results show that it achieves better performance in validity,speed and robustness.

关键词： ELM SLFNs training error Moore-Penrose generalized inverse selection algorithm

Sudden deafness as a prodrome of cerebellar artery infarction:Three case reports

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World Journal of Clinical Cases 2022年第15期10卷 4895-4903页

作者： bang-liang li Jia-Yuan Xu Sen lin Department of Ear Noseand ThroatThe Third Affiliated Hospital of Wenzhou Medical UniversityWenzhou 325000Zhejiang ProvinceChina

BACKGROUND To summarize the clinical characteristics of acute cerebral infarction(ACI)in patients with sudden deafness(SD)as the first symptom,improve the awareness of the disease,and help diagnosis and *** SUMMARY From 2019 to 2020,three patients with ACI with SD as the first symptom were admitted to our *** tone audiometry,head magnetic resonance imaging(MRI),vertebral artery and carotid artery B-ultrasound,head and neck computed tomography angiography,and other examinations were *** the treatment of SD,hearing and dizziness were not significantly ***,the patients developed symptoms of related cranial nerve injury,and brain MRI showed cerebral infarction in the cerebellopontine angle *** three cases were transferred to the neurology department for relevant conservative *** Patients with ACI with SD as the first symptom usually attend the otolaryngology *** a diagnosis of SD,which is based on an audiological examination,is made and the corresponding treatment is *** reduce the misdiagnosis of this disease,close attention should be paid to the changes in the patient's clinical symptoms and related auxiliary examinations should be performed,such as brain MRI and cerebrovascular *** should pay attention to the type and severity of hearing loss,the accompanying symptoms,age,high-risk factors for cerebral infarction,and related cranial nerve symptoms in patients with *** the patient's early brain MRI does not show abnormalities,monitoring remains *** head MRI should be analyzed quickly based on the changes in the symptoms of the patient,to make an accurate diagnosis and provide the timely and correct treatment for the patients.

关键词： Acute cerebral infarction Anterior inferior cerebellar artery Sudden deafness Case report

Diet characteristics of wild sheep(Ovis ammon darwini) in the Mengluoke Mountains,Xinjiang,China

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Journal of Arid Land 2018年第3期10卷 482-491页

作者： li bang XU Wenxuan David A BLANK WANG Muyang YANG Weikang Key Laboratory of Biogeography and Bioresource in Arid Land Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences Urumqi 830011 China Research Center for Ecology and Environment of Central Asia Bishkek 720001 Kyrgyzstan

In most arid and semi-arid regions of the world, domestic livestock and native wildlife share pastures, and their competition for forage and habitat is thought to be a serious conservation issue. Moreover, unmanaged grazing by livestock can cause the population decline in wild ungulates. The diet of an animal species is a determining aspect of its ecological niche, and investigating its diet has been one of the initial steps in basic ecology study of a new species. To get an approximate understanding of the interspecific food relationships of argali（Ovis ammon darwini） between sexes, and sympatric domestic sheep and goats, we compared the diet compositions and diet-overlaps among these herbivores, i.e., male argali, female argali, domestic sheep, and domestic goats in the Mengluoke Mountains of Xinjiang, China by using micro-histological fecal analysis. Female argali, male argali, domestic sheep and domestic goat primarily consumed forbs（43.31%±4.86%）, grass（36.02%±9.32%）, forbs（41.01%±9.18%）, and forbs（36.22%±10.61%）, respectively in warm season. All these animals consumed mostly shrubs（female argali： 36.47%±7.56%; male argali： 47.28%±10.75%; domestic sheep： 40.46%±9.56%; and domestic goats： 42.88%±9.34%, respectively） in cold season. The diet-overlaps were relatively high among all species in cold season with values ranging from 0.88 to 0.94. Furthermore, Schoener＇s index measured between each possible pair of 4 herbivores increased from the warm season to the cold season. The results illustrate that the high degree of diet-overlap of argali and domestic livestock（sheep and goat） may pose a threat to the survival of the argali in cold season. From the viewpoint of rangeland management and conservation of the endangered argali, the numbers of domestic sheep and goats should be limited in cold season to reduce food competition.

关键词： argali fecal analysis food habits competition diet-overlap

Experimental studies on rock failure mechanisms under impact load by single polycrystalline diamond compact cutter

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Petroleum Science 2023年第5期20卷 3100-3109页

作者： Zhao-Sheng Ji Jin-Bao Jiang Huai-Zhong Shi bang-Min li Drilling Engineering Technology Research Institute Sinopec Zhongyuan Petroleum Engineering CompanyPuyangHenan457001China State Key Laboratory of Petroleum Resources and Prospecting Beijing102249China

Percussive drilling shows excellent potential for promoting the rate of penetration(ROP)in drilling hard *** diamond compact(PDC)bits account for most of the footage drilled in the oil and gas *** reveal the rock failure mechanisms under the impact load by PDC bits,a series of drop tests with a single PDC cutter were conducted to four kinds of rocks at different back rake angles,drop heights,drop mass,and drop *** the morphology characteristics of the craters were obtained and quantified by using a three-dimensional *** fracture micrographs can be observed by using scanning electron microscope(SEM).The distribution and propagation process of subsurface cracks were captured in rock-like silica glass by a high-speed photography *** results can indicate that percussive drilling has a higher efficiency and ROP when the rock fractures in brittle *** failure mode of rock is related with the type of rock,the impact speed,and the back rake angle of the *** the penetration depth and fragmentation volume get the maximum values at a back rake angle of about 45°.Increasing the weight and speed of falling hammer is beneficial to improving the rock breaking effects and *** subsurface cracks under the impact load by a single PDC cutter is shaped like a clamshell,and its size is much larger than the crater *** findings can help to shed light on the rock failure mechanisms under the impact of load by a single PDC cutter and provide a theoretical explanation for better field application of percussive drilling.

关键词： Percussive drilling PDC cutter Drop test Failure mechanism Subsurface cracks

A pooled analysis of treatment and prognosis of hepatic angiosarcomain adults

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Hepatobiliary & Pancreatic Diseases International 2018年第3期17卷 198-203页

作者： De-bang li Xiao-Ying Si Tao Wan Yan-Ming Zhou Department Ⅲ of General Surgery The First Hospital of Lanzhou University Lanzhou 730000 China Department of Hepatobiliary & Pancreatovascular Surgery First Affiliated Hospital of Xiamen University Xiamen 361003 China

Background： Hepatic angiosarcoma is a rare malignant vascular tumor presenting unique treatment *** aim of the present study was to determine the treatment and prognosis of this *** sources： A systematic literature search was conducted using PubMed, Embase and Chinese Biomedicalliterature database, to identify articles published from January 1980 to July 2017. Search termswere “hepatic angiosarcoma” and “liver angiosarcoma”. Additional articles were retrieved through manualsearch of bibliographies of the relevant articles. Pooled individual data concerning the prognosis followingvarious therapeutic modalities were analyzed.

关键词： Hepatic angiosarcoma liver transplantation Hepatectomy Treatment Prognosis

Hyperlipidemia intensifies cerulein-induced acute pancreatitis associated with activation of protein kinase C in rats

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World Journal of Gastroenterology 2006年第18期12卷 2908-2913页

作者： Ya-Jun Wang Jia-bang Sun Fei li Shu-Wen Zhang Department of General Surgery Xuanwu Hospital of Capital University of Medical Sciences Beijing 100053 China

AIM： To investigate the effects of hyperlipidemia on acute pancreatitis （AP） and the possible mechanisms. METHODS： Rat models of hyperlipidemia and AP were established by Triton WR1339 and cerulein respectively. Human albumin was used to treat AP complicated by hyperlipidemia. In each group, we compared the histological score, volume of ascites, ratio of pancreatic wet/dry weight, serum amylase （AMY） and pancreatic acinar cell apoptosis. The level of protein kinase C （PKC） membrane translocation in pancreatic tissue was detected by Western blot.RESULTS： In the hyperlipidemia model established by Triton WR1339, triglyceride （TG） increased remarkably and reached its peak 6 h after injection, and most rats developed mild acute pancreatitis. Histological score, volume of ascites, ratio of wet/dry weight and serum AMY in AP animals with hyperlipidemia were obviously higher than those in AP animals （P 〈 0.05） and decreased after albumin therapy but not significantly （P 〉 0.05）. Apoptotic cells detected by terminal deoxynucleotidyl transferase-mediated dUTP-biotin nick end labeling （TUNEL） increased in AP animals with hyperlipidemia and did not change distinctly after albumin therapy. PKC membrane translocation level increased in AP animals with hyperlipidemia and decreased remarkably after albumin therapy （P 〈 0.05）.CONCLUSION： Hyperlipidemia may induce AP or intensify pancreatic injury. Albumin therapy can not alleviate pancreatic lesion effectively. PKC activation may be one mechanism by which AP is intensified by hyperlipidemia.

关键词： Acute pancreatitis Hyperlipidemia Protein kinase C

Emodin promoted pancreatic claudin-5 and occludin expression in experimental acute pancreatitis rats

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World Journal of Gastroenterology 2012年第17期18卷 2132-2139页

作者： Xian-Ming Xia bang-Ku li Shi-Mei Xing Hai-ling Ruan Department ofGastroenterology and Hepatology the Fourth Affiliated Hospital of Anhui Medical University Hefei 230022 Anhui ProvinceChina Department of Gastroenterology and Hepatology the First Affiliated Hospital of Anhui Medical University Hefei230022 Anhui Province China

AIM:To investigate the effect of emodin on pancreatic claudin-5 and occludin expression,and pancreatic paracellular permeability in acute pancreatitis(AP).METHODS:Experimental pancreatitis was induced by retrograde injection of 5% sodium taurocholate into the biliopancreatic *** was injected via the external jugular vein 0 or 6 h after induction of *** from sham operation and AP groups were injected with normal saline at the same *** of pancreas were obtained 6 or 12 h after drug *** morphology was examined with hematoxylin and eosin *** edema was estimated by measuring tissue water *** necrosis factor(TNF)-α and interleukin(IL)-6 level were measured by enzyme-linked immunosorbent *** paracellular permeability was assessed by tissue dye *** of pancreatic claudin-5 and occludin was examined by immunohistology,quantitative real-time reverse transcriptase polymerase chain reaction and western ***:Pancreatic TNF-α and IL-6 levels,wet/dry ratio,dye extravasation,and histological score were significantly elevated at 3,6 and 12 h following sodium taurocholate infusion;treatment with emodin prevented these changes at all time *** of claudin-5 and occludin was detected in rat pancreas,which was distributed in pancreatic acinar cells,ductal cells and vascular endothelial cells,*** taurocholate infusion significantly decreased pancreatic claudin-5 and occludin mRNA and protein levels at 3,6 and 12 h,and that could be promoted by intravenous administration of emodin at all time ***:These results demonstrate that emodin could promote pancreatic claudin-5 and occludin expression,and reduce pancreatic paracellular permeability.

关键词： Acute pancreatitis Paracellular permeability Emodin Claudin Occludin

Long-term outcomes of combined hepatocellular-cholangiocarcinoma after hepatectomy or liver transplantation: A systematic review and meta-analysis

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Hepatobiliary & Pancreatic Diseases International 2019年第1期18卷 12-18页

作者： De-bang li Xiao-Ying Si Shi-Jie Wang Yan-Ming Zhou Department Ⅲ of General Surgery the First Hospital of Lanzhou University Department of Hepatobiliary & Pancreatovascular Surgery First Affiliated Hospital of Xiamen University

Background: Combined hepatocellular-cholangiocarcinoma(cHCC-CC) is a rare primary liver malignancy. We conducted a systematic review and meta-analysis to assess the evidence available on the long-term outcomes of cHCC-CC patients after either hepatectomy or liver transplantation(LT). Data Sources: Relevant studies published between January 2000 and January 2018 were identified by searching Pub Med and Embase and reviewed systematically. Data were pooled using a random-effects model. Results: A total of 42 observational studies involving 1691 patients(1390 for partial hepatectomy and 301 for LT) were included in the analysis. The median tumor recurrence and 5-year overall survival(OS) rates were 65%(range 38%–100%) and 29%(range 0–63%) after hepatectomy versus 54%(range 14%–93%) and 41%(range 16%–73%) after LT, respectively. Meta-analysis found no significant difference in OS and tumor recurrence between LT and hepatectomy groups. Conclusion: Hepatectomy rather than LT should be considered as the prior treatment option for cHCC-CC.

关键词： Combined hepatocellular-cholangiocarcinoma liver transplantation Hepatectomy Treatment Prognosis

Congenital nephrogenic diabetes insipidus due to the mutation in AVPR2(c.541C>T)in a neonate:A case report

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World Journal of Clinical Cases 2020年第24期8卷 6418-6424页

作者： Fa-Tao lin Jing li bang-li Xu Xiu-Xiu Yang Fang Wang Department of Neonatology Children’s Hospital Affiliated to Zhengzhou UniversityHenan Children’s HospitalZhengzhou Children’s HospitalZhengzhou 450000Henan ProvinceChina Department of Infectious Diseases Children’s Hospital Affiliated to Zhengzhou UniversityHenan Children’s HospitalZhengzhou Children’s HospitalZhengzhou 450000Henan ProvinceChina

BACKGROUND Congenital nephrogenic diabetes insipidus (CNDI) is a rare hereditary renaldisorder that is caused by mutations in AVPR2 or aquaporin 2 (AQP2). Up tonow, there are few reports about CNDI in neonates. Early clinical manifestationsof CNDI in neonates are atypical. A lack of understanding of the disease byclinicians causes frequent misdiagnoses or missed diagnoses, which may result infailure to administer treatments in time and ultimately leads to severecomplications. In this study, clinical data of a case of AVPR2 gene mutationinducedCNDI, which was confirmed by genetic testing, were retrospectivelyanalyzed to improve our understanding of this *** SUMMARY On February 1, 2020, a male neonate was hospitalized 17 d after birth due to a 7 dperiod of pyrexia. The patient’s symptoms included recurrent pyrexia,hypernatremia and hyperchloremia, which were difficult to treat. The patient wasfed on demand, and water was additionally provided between milk intakes. Acombination treatment of hydrochlorothiazide and amiloride was *** the treatment, body temperature and electrolyte levels returned to normal,the volume of urine was significantly reduced and the patient was subsequentlydischarged. Genetic tests confirmed that the patient carried the AVPR2 genemissense mutation c.541C>T (P.R181C), and the patient’s mother carried aheterozygous mutation at the same locus. After clinical treatment with acombination of hydrochlorothiazide and amiloride, the body temperature andelectrolyte levels returned to normal. Up until the most recent follow-up examination, normal body temperature, electrolyte levels and growth anddevelopment were *** CNDI in the neonatal period is rare, and its clinical manifestations are unspecificwith some patients merely showing recurrent fever and electrolyte *** testing of AVPR2 and AQP2 can be used for screening and geneticdiagnosis of CNDI.

关键词： Neonate Congenital nephrogenic diabetes insipidus AVPR2 gene Gene mutation Magnetic resonance imaging Case report