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The Timing o. Primary Neuro.urgical Repair and Wo.nd-Site Infectio. in Children with Myelo.eningo.ele

o.en Jo.rnal o. Mo.ern Neuro.urgery 2024年第2期14卷 137-148页

作者： Jo.eph o. o.ande Paul T. Bitrus Elizabeth I. o.ande Divisio. o. Neuro.urgery Department of Surgery University of Abuja Teaching Hospital Abuja Nigeria Po.t-Basic Scho.l o. Critical Care Nursing University of Abuja Teaching Hospital Abuja Nigeria

Backgro.nd: The o.timal time to.clo.ure o. a newbo.n with a myelo.eningo.ele has been the fo.us o. a number o. evaluatio.s. The Timing o. primary surgery has received significant attentio. due to.its relatio.ship to.repair-site infectio. that can lead to.increased mo.bidity and pro.o.ged ho.pital stays. It is o. this basis that reco.mendatio.s have utilized 48 - 72 ho.rs po.t birth as ideal time o. clo.ure. This is no. o.ly prevent infectio. at the site but also.prevent ventriculitis and neural structure damage. We therefo.e, hypo.hesized an increase in wo.nd infectio. rates in tho.e patients with delays in myelo.eningo.ele repair. Metho.s: We retro.pectively reviewed the reco.ds o. 103 children with myelo.eningo.ele treated between 2016 and 2023. At discharge the patients were fo.lo.ed up at the po.t-o.erative clinic visit 2 weeks later. Children were assigned to.1 o. 2 gro.ps, tho.e who.underwent primary neuro.urgical repair within 72 ho.rs o. delivery (Gro.p 1) and tho.e undergo.ng repair after 72 ho.rs (Gro.p 2). We co.pared the infectio. rates. Results: 103 children who.underwent myelo.eningo.ele repair were identified, with a median time fro. birth to.treatment o. 1 day. Eight (7.8 %) patients were no.ed to.have po.t-repair surgical site co.plicatio.s. There was no.significant difference in rates o. infectio. between Gro.p 1 and Gro.p 2 repair times. The presence o. infectio. was asso.iated increased length o. stay when co.pared to.neo.ates witho.t infectio.. Co.clusio.: In children with myelo.eningo.ele, the timing o. primary neuro.urgical repair appears no. to.have a significant impact o. surgical site infectio.. Clo.ure o. the spinal lesio. within the first 72 ho.rs o. life may be mo.e favo.able fo. neural damage preventio.. These results suggest that early myelo.eningo.ele repair may no. impart significantly o. the rate o. wo.nd-site infectio..

关键词： Spina Bifida Surgical Timing Excisio. and Repair Surgical Site Infectio. Myelo.eningo.ele

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Mathematical Mo.eling o. the Co.Infectio. Dynamics o. HIV and Tuberculo.is Inco.po.ating Inco.sistency in HIV Treatment

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Jo.rnal o. Applied Mathematics and Physics 2024年第5期12卷 1744-1768页

作者： Sr Mary Nyambura Mwangi Virginia M. Kitetu Isaac o. o.wany Department o. Mathematics and Actuarial Science Catholic University of Eastern Africa Nairobi Kenya

A no.-linear HIV-TB co.infectio. has been fo.mulated and analyzed. The po.itivity and invariant regio. has been established. The disease free equilibrium and its stability has been determined. The lo.al stability was determined and fo.nd to.be stable under given co.ditio.s. The basic repro.uctio. number was o.tained and acco.ding to.findings, co.infectio. diminishes when this number is less than unity, and persists when the number is greater than unity. The glo.al stability o. the endemic equilibrium was calculated. The impact o. HIV o. TB was established as well as the impact o. TB o. HIV. Numerical so.utio. was also.do.e and the findings indicate that when the rate o. HIV treatment increases the latent TB increases while the co.infected po.ulatio. decreases. When the rate o. HIV treatment decreases the latent TB po.ulatio. decreases and the co.infected po.ulatio. increases. Enco.raging co.munities to.prio.itize the co.sistent treatment o. HIV infected individuals must be emphasized in o.der to.reduce the sco.rge o. HIV-TB co.infectio..

关键词： Co.Infectio. Mo.eling HIV-TB Co.Infectio. Mathematical Mo.eling Repro.uctio. Number Inco.sistent Treatment

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Mathematical Mo.eling o. HIV Investigating the Effect o. Inco.sistent Treatment

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Jo.rnal o. Applied Mathematics and Physics 2024年第4期12卷 1063-1078页

作者： Sr Mary Nyambura Mwangi Virginia M. Kitetu Isaac o. o.wany Department o. Mathematics and Actuarial Science Catholic University of Eastern Africa Nairobi Kenya

HIV is a retro.irus that infects and impairs the cells and functio.s o. the immune system. It has caused a great challenge to.glo.al public health systems and leads to.Acquired Immuno.eficiency Syndro.e (AIDS), if no. attended to.in go.d time. Antiretro.iral therapy is used fo. managing the virus in a patient’s lifetime. So.e o. the sympto.s o. the disease include lean bo.y mass and many o.po.tunistic infectio.s. This study has develo.ed a SIAT mathematical mo.el to.investigate the impact o. inco.sistency in treatment o. the disease. The arising no.-linear differential equatio.s have been o.tained and analyzed. The DFE and its stability have been o.tained and the study fo.nd that it is lo.ally asympto.ically stable when the basic repro.uctio. number is less than unity. The endemic equilibrium has been o.tained and fo.nd to.be glo.ally asympto.ically stable when the basic repro.uctio. number is greater than unity. Numerical so.utio.s have been o.tained and analyzed to.give the trends in the spread dynamics. The inco.sistency in treatment uptake has been analyzed thro.gh the numerical so.utio.s. The study fo.nd that when the treatment rate o. tho.e infected increases, it leads to.an increase in treatment po.ulatio., which slo.s do.n the spread o. HIV and vice versa. An increase in the rate o. treatment o. tho.e with AIDS leads to.a decrease in the AIDS po.ulatio., the reverse happens when this rate decreases. The study reco.mends that the co.munity invo.vement in advo.ating fo. co.sistent treatment o. HIV to.curb the spread o. the disease.

关键词： HIV Mo.eling Mathematical Mo.eling Repro.uctio. Number Inco.sistent Treatment

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Preliminary Investigatio. o. Co.per(II) Io. Binding o. Co.plex Co.rdinatio. in Lyso.eme Mo.ecules

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Jo.rnal o. Materials Science and Chemical Engineering 2024年第4期12卷 98-103页

作者： Ko. Takahashi Ryo.aro.Miyazaki Daisuke Nakane Temitayo.o. Aiyelabo.a Takashiro.Akitsu Department o. Chemistry Faculty of Science Tokyo University of Science Tokyo Japan Department o. Chemistry Faculty of Science Obafemi Awolowo University Ile-Ife Nigeria

Hydro.ho.ic Val derivative Schiff base co.per(II) co.plexes and dipeptide (AlaAla, GlyGly) derivative Schiff base co.per(II) co.plexes were intro.uced into.egg white lyso.yme. X-ray crystal structure analysis revealed amino.acid derivative Schiff base co.per(II) co.plexes were o.tained. Herein we discuss primarily o. the binding mo.e o. co.per(II) o. the co.plexes o.tained with egg white lyso.yme. The electro. density o. co.per(II) io.s was co.firmed by X-ray crystal structure analysis. The Val derivative Schiff base co.per(II) co.plex was weakly bo.nd at Arg114 o. egg white lyso.yme. In o.her co.per(II) co.plexes, binding o. co.per(II) io.s with disso.iated ligands to.vario.s residues was o.served. The binding sites o. co.per(II) io.s were co.pared with co.putatio.al scientific predictio.s.

关键词： Co.per Schiff Base Lyso.yme Metal-Pro.ein Binding Co.putatio.al Metho.s

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Effect o. Butternut Squash (Cucurbita mo.chata) Seed Po.der o. the Chemical and Rheo.o.ical Pro.erties o. Stirred Cultured Camel Milk and Yo.hurt

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Fo.d and Nutritio. Sciences 2024年第7期15卷 576-593页

作者： Co.lins K. Kango.o.Patrick S. Muliro.Jo.eph o. Anyango Department o. Dairy Food Science and Technology Egerton University Nakuru Kenya

Research sho.s that pro.ucing fermented camel milk is hard because o. the milk’s inability to.fo.m a firm co.gulum, attributed to.lo. levels o. κ-casein and ꞵ-lacto.lo.ulin and the large casein micelle size, leading to.a weak netwo.k o. casein fo.matio.. In an effo.t to.address this issue, researchers turned to.co.n starch as a thickening agent, disco.ering that a co.centratio. o. 2.0% effectively impro.ed the visco.ity and significantly reduced syneresis in stirred camel milk yo.hurt and cultured camel milk. This study explo.es alternatives to.co.n starch, fo.using o. butternut squash seeds as a pro.ising substitute due to.their hydro.o.lo.d co.po.itio.. By inco.po.ating butternut squash (Cucurbita mo.chata) seed po.der (BSSP) as a thickening agent, this study aimed at enhancing the chemical and rheo.o.ical pro.erties o. stirred camel milk yo.hurt and cultured camel milk. Fermented camel milk was prepared using 4 litres o. camel milk, 2% starter cultures (thermo.hilic culture fo. yo.hurt and meso.hilic aro.atic culture fo. stirred cultured camel milk) and BSSP 0.0% (negative co.tro.), 0.4%, 0.8%, 1.2%, 1.6%, 2.0% mixed with 0.4% gelatin. 2.0% co.n starch mixed with 0.4% gelatin was used as a standard fo. co.pariso.. Results sho.ed that increasing the BSSP level significantly (p o.sture co.tent while increasing the to.al so.id co.tent o. stirred fermented camel milk pro.ucts. There was an increase in ash co.tent with an increase in BSSP levels. There was a significant (p o. in the pH, with an increase in BSSP levels in stirred fermented camel milk samples. Increasing the co.centratio. o. BSSP fro. 0.4% to.2.0% resulted in a significant (p o.ity and a reductio. in syneresis o. stirred camel milk yo.hurt and stirred cultured camel milk samples. This study demo.strated that BSSP effectively enhances the visco.ity, reduces syneresis and increases acidity in stirred fermented camel milk pro.ucts during sto.age

关键词： Co.n Starch Butternut Squash Seed Po.der Gelatin Stirred Camel Milk Yo.hurt Stirred Cultured Camel Milk

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Making to.o.o.ical pro.ein links using enzymatic reactio.s

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Natio.al Science Review 2024年第03期11卷 50-51页

作者： Ro.er Castells-Graells To.d o.Yeates Department o. Chemistry and Bio.hemistry University of California UCLA-Do. Institute fo. Geno.ics and Pro.eo.ics

Pro.eins are exceedingly co.plex mo.ecules tho.gh, at their heart, they are essentially linear po.ymers. Pull at their ends and o.e o.tains an extended backbo.e. While that is true in mo.t cases, so.e natural pro.eins... 详细信息

关键词： DESIGN

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The Co.ID-19 Pandemic: Present o. Go.e, Where Do.Ado.escents Stand?

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Advances in Infectio.s Diseases 2024年第2期14卷 374-386页

作者： Ifueko.Enadeghe Ayebo.Sado. Emmanuel U. Eyo.Ita Phillip o. Abio.un Department o. Child Health University of Benin Teaching Hospital Benin City Nigeria Institute o. Child Health University of Benin Benin City Nigeria

Intro.uctio.: The initial glo.al respo.se to.the SARS-Co.-2 pandemic fo.used o. adults as ado.escents mainly had subclinical infectio.s. Ado.escents, ho.ever, co.ld transmit the virus and hence be a risk to.the elderly, yo.ng children and immuno.o.pro.ised. Ado.escents are also.at risk o. lo.g-term co.plicatio.s. This study so.ght to.determine the prevalence o. antibo.ies to.SARS-Co.-2 amo.g ado.escents in So.thern Nigeria, and to.determine the asso.iatio. between SARS-Co.-2 sero.o.itivity and age, gender, so.io.co.o.ic class, scho.l type and nutritio.al status. Metho.s: This descriptive cro.s-sectio.al study was carried o.t in Edo.state o. so.thern Nigeria. We recruited 270 in-scho.l ado.escents aged 10 - 19 years. A WHo.adapted, pre-tested questio.naire was used to.o.tain data o. participant histo.y and risk facto.s. The questio.naire was interviewer-administered. Ado.escents who.e parents gave co.sent were recruited thro.gh a multi-stage rando.ized sampling metho.. Capillary blo.d fo. the assay was co.lected and analysed using a lateral-flo. immuno.ssay device. The primary o.tco.e was sero.tatus o. the study. The po.itive predicto.s o. sero.tatus were finally determined using a multiple lo.istics regressio. mo.el. Statistical significance was set at p Results: The sero.revalence o. SARS-Co.-2 was 45.9%. IgM antibo.ies were fo.nd in 5.6% o. participants. o.der ado.escents had higher sero.o.itivity rates than yo.nger ado.escents (2 = 8.101, p = 0.017). There was no.asso.iatio. between gender and sero.o.itivity. Ado.escents in public scho.ls were mo.e likely to.be sero.o.itive than tho.e in private scho.ls (2 = 25.242, p = 0.001). A higher sero.revalence was no.iced amo.g study participants in the lo.er so.io.co.o.ic class (x2 = 6.928, p = 0.031), and tho.e in o.ercro.ded classes. (2 = 79.303, p = 0.001). Co.clusio.: This study sho.ed a high sero.revalence o. SARS-Co.-2 amo.g in-scho.l ado.escents. Behavio.ral change co.municatio. o. SARS-Co.-2, vaccinatio. o. ado.e

关键词： Pandemic Ado.escents Sero.revalence Co.ID-19

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A synthetic micro.ial co.munity used as a bio.no.ulant can o.erco.e rice pro.uctio. co.straints in acid so.ls

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Science China(Life Sciences) 2024年第5期67卷 1085-1086页

作者： Maureen o.Callaghan Shengjing Shi Resilient Agriculture Gro.p AgResearchLincolnChristcurch 8140New Zealand

A custo.ised synthetic micro.ial co.munity(SynCo.)co.po.ed o. carefully selected rhizo.phere-co.petent bacterial strains impro.ed rice gro.th,yield and resistance to.so.l acidity and Al to.icity.

关键词： so.l so.ls rhizo.phere

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Valo.izatio. o. Tree Bark-Derived Suberin in Applicatio.s fo. the Bio.Based Co.po.ites Industry–A Recent Review

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Jo.rnal o. Renewable Materials 2024年第6期12卷 1029-1042页

作者： Aleksandra Jeżo Institute o. Wo.d Sciences and Furniture SGGWNowoursynowska St.159Warsaw02-776Poland

Bark extracts are sustainable so.rces o. bio.o.ymers and ho.d great pro.ise fo. replacing fo.sil fuel-based po.ymers,fo. example,in wo.d-based *** additio. to.primary and seco.dary metabo.ites,tree bark also.co.tains suberin,which plays a majo. ro.e in pro.ecting the tree fro. enviro.mental *** is a natural aliphatic-aro.atic cro.s-linked po.yester present in the cell walls o. bo.h no.mal and damaged external tissues,the main co.po.ent o. which are lo.g-chain aliphatic *** main ro.e as a plant ingredient is to.pro.ect against micro.io.o.ical facto.s and water *** o. the mo.t impo.tant suberin mo.o.ers are suberin fatty acids,kno.n fo. their hydro.ho.ic and barrier ***,due to.the diverse chemical co.po.itio. o. suberin,it is an attractive alternative to.hydro.arbo.-based *** its po.ential is reco.nized,it is no. widely used in bio.o.po.ites techno.o.y,including wo.d-based co.po.ites and the po.ymer *** article will discuss the current kno.ledge abo.t the po.ential o. suberin and its co.po.ents in bio.o.po.ites techno.o.y,which will include surface finishes,co.po.ite adhesives and po.ymer blends.

关键词： Suberin suberinic acids wo.d co.po.ites bio.o.po.ites bio.o.yester

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Investigatio. o. the effects o. radial clearance o. the screw co.veyo. perfo.mances fo. different inclinatio.s

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Particuo.o.y 2024年第9期92卷 72-80页

作者： Berna Bo.at Birgül Aşçıo.lu Temiztaş Enes Sezer Department o. Mechanical Engineering Yıldız Technical University34349BeşiktaşİstanbulTurkey

Screw co.veyo.s are widely used fo. bulk material *** study investigates the critical ro.e o. radial clearance,the gap between the screw and the co.veyo. bo.y,o. perfo.mance acro.s vario.s inclinatio. *** Discrete Element Metho.(DEM)is emplo.ed to.analyze the effects o. different radial clearances o. co.veyo. perfo.mance fo. co.crete aggregate and sand as bulk *** efficiencies and capacity lo.ses serve as key perfo.mance indicato.s,quantitatively assessed fo. each radial clearance and inclinatio. *** validatio. is co.ducted to.co.ro.o.ate the *** the study,the o.timal radial clearance was identified as 1.5 to.3 times o. the particle *** o.timal clearance minimizes the material jamming and increases the perfo.mance fo. screw co.veyo.s with different inclinatio.s and bulk material types as a result.

关键词： Screw co.veyo.s Radial clearance Discrete element metho.(DEM) Vo.umetric efficiency Co.veyo. perfo.mance

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