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Chemical composition, nutritional values, elemental analysis and biological properties of Prunus mahaleb L.: From waste to new potential sources for food, cosmetic and drug industry

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FOOD BIOSCIENCE 2023年第3期53卷 3189-3196页

作者： Guven, Zuhal Bayrakceken Alshehri, Osama Yuce, Neslihan bakan, ebubekir Demirci, Betul Yilmaz, Mustafa Abdullah Ertas, Abdulselam Basaran, A. Ahmet Hacettepe Univ Fac Pharm Dept Pharmacognosy Ankara Turkiye Saudi FDA Nafal Unit 1 N Ring Rd Al Riyadh 03292 Saudi Arabia Ataturk Univ Fac Med Dept Biochem Erzurum Turkiye Anadolu Univ Fac Pharm Dept Pharmacognosy Eskisehir Turkiye Dicle Univ Fac Pharm Dept Analyt Chem Diyarbakir Turkiye Baskent Univ Fac Pharm Dept Pharmacognosy Ankara Turkiye Erzincan Binali Yildirim Univ Fac Pharm Dept Pharmacognosy Erzincan Turkiye

Prunus mahaleb L. seeds are widely used in the baking industry as spice for flavouring. While achieving the mahaleb powder for commercial use in local companies, the seeds are sometimes mixed unintentionally with their kernels (stony shell) during sieving procedure. As the chemical and biological properties of the kernel of seeds are not well known, the kernel, seeds and the market sample obtained from a local supplier are decided to investigate individually. The antioxidant capacity and the trace element analyses of the seeds and kernels were performed by TEAC and CUPRAC assays and ICP-MS. The market sample was analysed for nutrient and oil composition. Fatty acid composition of the oil was determined with GC-FID and GC-MS methods. The chemical composition of the methanol extract of the seeds and kernels was studied by LC-MS/MS. Trace elements Mn, Co, Ni, Cu, Zn and Se were determined in the methanol extracts, ethyl acetate and water fractions. Mushroom tyrosinase enzyme inhibitions of 33 different extracts and fractions of various waste parts of the plant (kernel, fruit, twigs, flos, leaves) were investigated. The nutritional values showed that the market sample had high nutritious properties. The fatty acid content of the oil was found to be valuable in remedying dysfunctions of the body. Kernel ethylacetate fraction showed the highest tyrosinase enzyme inhibition. The role of copper element on enzyme activity was determined. The kernels are accepted as a waste material may also be evaluated as a good promising choice for food, cosmetic and drug industry.

关键词： Prunus mahaleb L seeds Kernels Tyrosinase Trace elements Nutritional value Fatty acid content

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Highly efficient three-phase grid-connected parallel inverter system

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Journal of Modern Power Systems and Clean Energy 2018年第5期6卷 1079-1089页

作者： Evren ISEN Ahmet Faruk bakan Department of Electrical and Electronics Engineering Kirklareli University Department of Electrical Engineering Yildiz Technical University

In this paper, a new three-phase grid-connected inverter system is proposed. The proposed system includes two inverters. The main inverter, which operates at a low switching frequency, transfers active power to the grid. The auxiliary inverter processes a very low power to compensate for the grid current ripple. Thus, no active power is processed by the auxiliary inverter. The goal is to produce a grid current with a low total harmonic distortion(THD) and to obtain the highest efficiency from the inverter system. The main inverter is controlled via a space-vector pulse-width modulation owing to its optimum switching pattern, and the auxiliary inverter is controlled via a hysteresis current-control technique owing to the technique's fast dynamic response. The proposed system is analyzed in terms of different DC-link voltage, switching frequency,and filter inductance values. The optimum system parameters are selected that provide a THD value of less than 5%.A prototype inverter system at a 10 kW output power has been implemented. The main inverter operates at a 3 kHz switching frequency, and the auxiliary inverter compensates for the grid-current ripple. In total, a THD of 4.33%and an efficiency of 97.86% are obtained using the proposed inverter system prototype.

关键词： Active filter Inverter efficiency Ripple cancellation Three-phase grid-connected inverter

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Anesthetic management of the SRS^(TM) endoscopic stapling system for gastro-esophageal reflux disease

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World Journal of Gastroenterology 2013年第2期19卷 319-320页

作者： Ufuk Topuz Tarik Umutoglu Mefkur bakan Erdogan Ozturk Department of Anesthesiology and Reanimation Bezmialem Vakif University Faculty of Medicine34093 IstanbulTurkey

The SRS TM Endoscopic Stapling System(Medigus,Tel Aviv,Israel) is a new tool capable of creating a totally endoscopic fundoplication,combined with an endoscope,endoscopic ultrasound and a surgical *** TM endoscopic stapling for gastro-esophageal reflux disease is a minimally invasive,outpatient procedure,which requires general anesthesia with positive-pressure *** the patient on positive endexpiratory pressure(PEEP) may minimize the pressure gradient between the esophagus and the mediastinum,as well as help to prevent air from leaking around the screws and causing *** addition,in patients with hiatal hernia,higher PEEP levels may be required to increase intra-thoracic pressure and to force the stomach to slide into the abdomen for ease of *** advise smoother emergence from anesthesia,taking precautions for retching,postoperative nausea and vomiting(PONV),while coughing and gagging during extubation and PONV may affect the success of the *** intravenous anesthesia with propofol and remifentanil seems to be a good choice for these reasons.

关键词： Gastro-esophageal reflux disease Endoscopy Anesthesia SRS TM endoscopic stapling system Positive end-expiratory pressure

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Relationship between fall risks and activities of daily living in older individuals

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Frontiers of Nursing 2020年第3期7卷 249-256页

作者： Senay Karadag Arli Metin Yildiz Ayse Berivan bakan Department of Nursing Agri Ibrahim Cecen University School of HealthAgri 04100Turkey

Objective:To investigate the relationship between fall risks and maintaining activities of daily living in individuals aged 65 and ***:This study is *** was conducted with 233 individuals who were aged 65 and over in Family Health Centers located in the eastern part of Turkey between February and June ***:The mean older individuals’DENN Fall Risks Assessment Scale score was 11.73±7.13,and 62.2%of the participants were in the high-risk *** Index of Activities of Daily Living(ADL)mean score was 68.03±25.36,and 45.1%of the participants were in the moderately dependent *** was a statistically significant,negative correlationship between Barthel Index of ADL score and age and DENN Fall Risks Assessment Scale *** addition,there was a statistically significant,positive relationship between the DENN Fall Risks Assessment Scale score and age(p<0.01).Conclusions:This study found that level of dependency and fall risks increased with the increase in *** global and multidisciplinary interventions are needed to decrease older individuals’dependency levels and fall risks today when the number of older individuals is increasing.

关键词： activities of daily living dependency older fall risk

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Laser-assisted dacryocystorhinostomy in nasolacrimal duct obstruction：5-year follow-up

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International Journal of Ophthalmology(English edition) 2018年第10期11卷 1616-1620页

作者： Mustafa Dogan Anar Alizada Güliz Fatma Yavas Orhan Kemal Kahveci Osman bakan Department of Ophthalmology Faculty of Medicine AfyonKocatepe University Afyonkarahisar 03200 Turkey Department of Ophthalmology Faculty of MedicineHacettepe Univerisity Ankara 06100 Turkey Department of Otolarhinoaryngology Faculty of MedicineAfyon Kocatepe University Afyonkarahisar 03200 Turkey Medlife Hospital istanbul 34500 Turkey

AIM：To evaluate the long-term sucess rate of laserassisted dacryocystorhinostomy （L-DCR） in patients with nasolacrimal duct obstruction （NDO）.METHODS：Forty-one eyes of forty patients aged between 21-85y （mean 56.7y） who underwent L-DCR for the treatment of NDO were included in this retrospective,non-randomized study. The follow-up time was *** sucess was defined as the disappearance of epiphora under normal conditions and the presence of a patent ostium on lacrimal irrigation. Anatomical success was defined as a patent lacrimal passage on syringing besides continuing epiphora. Surgical failure was defined as persistent epiphora and closed ***：Twenty-seven of 40 patients （67.5%） were female and 13 of 40 patients （32.5%） were male. The NDO was right-sided in 17 （42.5%） patients and left-sided in 22（55%） patients whereas 1 （2.5%） patient had undergone bilateral surgery. In 11 （27.5%） patients there were additional nasal abnormalities requiring simultaneous surgical approach. The average time for L-DCR was 26.50±4.9min（16-39min） and the average total amount of laser energy used was 287±27.9 J （239-367 J）. At the 5y follow-up, anatomical sucess rate was 75.0%（30 patients） and functional success rate was 65.0%（26 patients）, whereas surgical failure was seen in 25%（10 patients）. Revision of surgery was performed in 10 cases （25.0%）; failure of revision surgery was seen in 2 cases（5.0%）.CONCLUSION： Transcanalicular L-DCR is a reliable and fast procedure in the treatment of NDO. It can be alternative to external DCR which is accepted as the gold standard currently. The functional and anatomical success rate is higher in the first months and years, but still satisfactory at fifth year.

关键词： nasolacrimal duct obstruction laser-assisted dacryocystorhinostomy 5-year follow-up

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The SlSHN2 transcription factor contributes to cuticle formation and epidermal patterning in tomato fruit

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Molecular Horticulture 2022年第1期2卷 186-205页

作者： Cecile Bres Johann Petit Nicolas Reynoud Lysiane Brocard Didier Marion Marc Lahaye Benedicte bakan Christophe Rothan UMR 1332 BFP INRAEUniversite de Bordeaux33140 Villenave d’OrnonFrance Unite Biopolymeres InteractionsAssemblagesINRAEBP7162744316 Nantes Cedex 3France Univ.Bordeaux CNRSINSERMBordeaux Imaging CenterBICUMS 3420US 433000 BordeauxFrance INRA UMR1332 Biologie du Fruit Et Pathologie71 Av Edouard Bourlaux33140 Villenave d’OrnonFrance

Tomato(Solanum lycopersicum)is an established model for studying plant cuticle because of its thick cuticle covering and embedding the epidermal cells of the *** this study,we screened an EMS mutant collection of the miniature tomato cultivar Micro-Tom for fruit cracking mutants and found a mutant displaying a glossy fruit *** using an established mapping-by-sequencing strategy,we identified the causal mutation in the SlSHN2 transcription factor that is specifically expressed in outer epidermis of growing *** point mutation in the shn2 mutant intro-duces a K to N amino acid change in the highly conserved‘mm’domain of SHN *** cuticle from shn2 fruit showed a~fivefold reduction in cutin while abundance and composition of waxes were barely *** addition to alterations in cuticle thickness and properties,epidermal patterning and polysaccharide composition of the cuticle were *** analysis further highlighted the altered expression of hundreds of genes in the fruit exocarp of shn2,including genes associated with cuticle and cell wall formation,hormone signaling and response,and transcrip-tional *** conclusion,we showed that a point mutation in the transcriptional regulator SlSHN2 causes major changes in fruit cuticle formation and its coordination with epidermal patterning.

关键词： Mutant SHINE Cuticle Epidermis Cell wall Ethylene

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科威特油井大火的烟尘对气候的影响

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气象科技 1992年第1期20卷 18-22页

作者： S.bakan 王坚

通过使用包含具有反馈机制的烟尘传输过程和扩展的辐射过程的一个海-气耦合全球环流模式,进行了一系列数值试验,以研究科威特油井大火的烟雾对全球气候系统的影响.结果表明,海湾地区地面气温降低了4℃,海湾以外地区的变化较小,统计上亦... 详细信息

通过使用包含具有反馈机制的烟尘传输过程和扩展的辐射过程的一个海-气耦合全球环流模式,进行了一系列数值试验,以研究科威特油井大火的烟雾对全球气候系统的影响.结果表明,海湾地区地面气温降低了4℃,海湾以外地区的变化较小,统计上亦不显著.没有发现印度夏季季风会减弱.

关键词：烟尘气候影响采油井火灾

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Music of death and new creation : experiences in the world of Balinese gamelan beleganjur

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1999年

作者： bakan Michael B.

来源：畅想之星图书光盘版（南... 评论

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Cranial Magnetic Resonance Spectroscopy: An Update of Metabolites and a Special Emphasis on Practical Points

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Open Journal of Medical Imaging 2014年第4期4卷 163-171页

作者： Duzgun Yildirim Onur Tutar Deniz Alis Gokhan Kuyumcu Selim bakan Centermed Advanced Imaging Center Istanbul Turkey Depatment of Radiology Cerrahpasa Medical Faculty Istanbul University Istanbul Turkey

Magnetic resonance spectroscopy (MRS) could be used for dozens of metabolites [1]. In this paper we will focus especially on proton (hydrogen) MRS. Generally published literatures consist of reviews and articles about metabolites are long, complicated and emphasise on physical or on technical data. But with this article, we will try to explain basically how MRS could be used in daily practice of radiologists. First of all we tried to search all current literature only referencing the main ones to make this review and we want all of our colleagues to give feedback about this review. With collection of all these trick points and line up to appropriate order, it is possible to make this review a common guide for radiologists and a useful tool while reporting MRS.

关键词： Magnetic Resonance Spectroscopy Analysis Metabolite Markers Radiology

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A rare complication of a rare disease: Amyloidosis in situs inversus

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Open Journal of Internal Medicine 2013年第2期3卷 55-57页

作者： Abdullah Ozkok Mirac Vural Keskinler Erhan Eken Osman Kostek Ozge Caklili Alihan Oral Kubra Aydin Bahat Omer Celal Elcioglu Ali bakan Ali Riza Odabas Istanbul Medeniyet University Goztepe Training and Research Hospital Nephrology Clinic Istanbul Turkey

A 31-year-old female admitted with productive cough and progressively increasing edema in her legs. Four years ago she had the diagnosis of situs inversus (SI) totalis. She had6.5 g/day proteinuria in 24-hour urine analysis. High resolution computed tomography revealed bronchiectatic areas in the left lung. In renal biopsy, kongo and amyloid AA antibody positivity was detected in arteriolar walls and mesangial areas. The patient is currently being followed with ramipril and colchicine treatments. Primary ciliary dyskinesia (PCD) and resultant SI totalis are very rare anomalies characterized by the total inversion of all organs and chronic bronchiectasis. There are very few reports on the association of SI totalis with nephrotic syndrome. Patients with SI totalis and chronic bronchiectasis have increased risk of AA amyloidosis and possibly end stage renal disease and thus these patients should be regularly followed with proteinuria and serum creatinine levels.

关键词： Situs Inversus Amyloidosis Bronchiectasis Nephrotic Syndrome

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