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World Journal of Gastroenterology 2016年第19期22卷 4766-4775页

作者： Zhi-Qiang song Li-Ya Zhou Department of Gastroenterology Peking University Third Hospital

AIM: To compare hybrid therapy(HT) with traditional sequential therapy(ST) and concomitant therapy(CT) for Helicobacter pylori(H. pylori) ***: We performed an electronic search of Pub Med, Embase, and the CENTRAL database. Randomized controlled trials(RCTs) of HT were included in the meta-analysis. The primary outcome was the eradication rate of H. pylori. The secondary outcomes included the compliance rate and adverse event rate. Effect estimates were pooled using the random-effects ***: Twelve studies were included. Pooled results showed no significant differences in eradication rate between HT and ST in per-protocol(PP) analysis(RR = 1.03, 95%CI: 0.94-1.12, P = 0.59) or in intention-totreat(ITT) analysis(RR = 1.00, 95%CI: 0.89-1.12, P = 0.94). HT and ST showed similarly high compliance rate(96% vs 98%, P = 0.55) and acceptable adverse event rate(30.3% vs 28.2%, P = 0.63). No significant results were seen in the eradication rate between HT and CT in PP analysis(RR = 1.01, 95%CI: 0.96-1.05, P = 0.76) or in ITT analysis(RR = 0.99, 95%CI: 0.95-1.03, P = 0.47). HT displayed a slightly higher compliance rate than CT(95.8% vs 93.2%, P < 0.05). The adverse event rates of HT and CT were similar(39.5% vs 44.2%, P = 0.24).CONCLUSION: Compared with ST or CT, HT yields a similar eradication rate, high compliance rate, and acceptable safety profiles.

关键词： Hybrid therapy Sequential therapy Concomitant therapy Helicobacter pylori Meta-analysis

An Improved Immune Clone Selection Algorithm for Parameters Optimization of Marine Electric Power System Stabilizer

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Energy Engineering 2022年第3期119卷 907-928页

作者： Zong Bi Weifeng Shi Tiewei song Department of Electrical Engineering Shanghai Maritime UniversityShanghai201306China

In themarine electric power system,the marine generators will be disturbed by the large change of loads or the fault of the power *** marine generators usually installed power system stabilizers to damp power system oscillations through the excitation *** paper proposes a novel method to obtain optimal parameter values for Power System Stabilizer(PSS)to suppress low-frequency oscillations in the marine electric power *** this paper,a newly developed immune clone selection algorithm was improved from the three aspects of the adaptive incentive degree,vaccination,and adaptive mutation ***,the typical PSS implementation type of leader-lag structure was adopted and the objective function was set in the optimization *** performance of PSS tuned by improved immune clone selection algorithm was compared with PSS tuned by basic immune clone selection algorithm(ICSA)under various operating conditions and ***,an improved immune clone selection algorithm(IICSA)optimization technique was implemented on two test systems for test *** on the simulations,it is found that an improved immune clone selection algorithm demonstrates superiority over the basic immune clone selection algorithm in getting a smaller number of iterations and fast convergence rates to achieve the optimal parameters of the power system ***,the proposed approach improves the stability and dynamic performance under various loads conditions and disturbances of the marine electric power system.

关键词： Marine electric power system excitation system immune clone selection algorithm low frequency oscillations power system stability

The investigation on computational grids in wind turbine positioning optimization using greedy algorithm

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Chinese Science Bulletin 2014年第26期59卷 3304-3313页

作者： Kai Chen Mengxuan song Xing Zhang Department of Engineering Mechanics Key Laboratory for Thermal Science and Power Engineering of Ministry of Education Tsinghua University

In this paper, the effect of the computational grids on the wind turbine positioning optimization is studied. The linear wake flow model is used to calculate the turbine wake flow. The power law is used to model the power curve of wind turbine. Greedy algorithm with repeated adjustments is introduced to solve the wind turbine positioning problem, with the target of maximizing the total power output of wind farm. Square grid and triangle grid with various orientations are used to discretize the area of wind farm. Three numerical cases are introduced to study the effect of the computational grids on the optimized results. The results show that the optimized power output can be improved through choosing appropriate grid orientation. The suggested grid orientations for single direction wind case and multi-direction wind case are given.

关键词：风力涡轮机计算网格定位问题优化贪心算法格调尾流模型功率输出

China’s global engagement to fight the novel coronavirus pandemic

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Global Health Research and Policy 2020年第1期5卷 104-107页

作者： Wei song CAITEC International Development Cooperation Institute No.28 DonghouxiangAnwaiBeijing 100710China

The world is confronted by the current pandemic of coronavirus disease 2019(COVID-19),which is a common threat to the whole of *** the process of fighting COVID-19 domestically,China had attached great importance to international cooperation,such as the sharing of information on the pandemic with the international community,providing bilateral and multilateral assistance to other affected countries,***,due to the severity of this pandemic,global solidarity is necessary to conquer it,and to improve global public health governance.

关键词： China Official development aid COVID-19 Pandemic

Multiscale Radiative Transfer in Cylindrical Coordinates

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Communications on Applied Mathematics and Computation 2019年第1期1卷 117-139页

作者： Wenjun Sun song Jiang Kun Xu Institute of Applied Physics and Computational Mathematics P.O.Box 8009Beijing 100088China Department of Mathematics Hong Kong University of Science and TechnologyClear Water BayKowloonHong KongChina

The radiative transfer equations in cylindrical coordinates are important in the application of inertial confinement *** comparison with the equations in Cartesian coordinates,an additional angular derivative term appears in the cylindrical *** term adds great difficulty for a numerical scheme to keep the conservation of total *** this paper,based on weighting factors,the angular derivative term is properly discretized,and the interface fluxes in the radial r-direction depend on such a discretization as well.A unified gas kinetic scheme(UGKS)with asymptotic preserving property for the gray radiative transfer equations is constructed in cylindrical *** current UGKS can naturally capture the radiation diffusion solution in the optically thick regime with the cell size being much larger than photon's mean free *** the same time,the current UGKS can present accurate solutions in the optically thin regime as ***,it is a finite volume method with total energy *** to the scale-dependent time evolution solution for the interface flux evaluation,the scheme can cover multiscale transport mechanism *** cylindrical hohlraum tests in inertial confinement fusion are used to validate the current approach,and the solutions are compared with implic让Monte Carlo result.

关键词： Cylindrical coordinate system Gray radiative equations Multiscale transport Unified gas kinetic scheme

Mammary stem cells:angels or demons in mammary gland?

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Signal Transduction and Targeted Therapy 2017年第1期2卷 312-319页

作者： Xueman Chen Qiang Liu Erwei song Breast Tumor Center Sun Yat-Sen Memorial HospitalSun Yat-Sen UniversityGuangzhouChina Guangdong Provincial Key Laboratory of Malignant Tumour Epigenetics and Gene Regulation Medical Research CenterSun Yat-Sen Memorial HospitalSun Yat-Sen UniversityGuangzhouChina

A highly dynamic development process exits within the epithelia of mammary gland,featuring morphogenetic variation during puberty,pregnancy,lactation,and *** identification of mammary stem cells(MaSCs)via lineage-tracing studies has substantiated a hierarchical organization of the mammary epithelia.A single MaSC is capable of reconstituting the entirely functional mammary gland upon orthotopic *** different mammary cell subpopulations can be candidate cells-of-origin for distinct breast tumor subtypes,it still lacks experimental proofs whether MaSCs,the most primitive cells,are the‘seeds’of malignant transformation during most,if not all,tumorigenesis in the ***,we review current knowledge of mammary epithelial hierarchy,highlighting the roles of mammary stem/progenitor cells and breast cancer stem cells(BCSCs)along with their key molecular regulators in organ development and cancer *** these issues will pave the way for developing novel interventions toward stem/progenitor cells in either prevention or treatment of breast cancer(BrCa).

关键词： prevention breast entirely

相对性视角下管理类论文创新点的构成要素分析及应用

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科技管理研究 2015年第10期35卷 250-254页

作者：白胜宋李荣西南政法大学管理学院重庆401120

让管理类论文具有创新点是研究者必须做却又很难做的事。归纳出创新点的本质为相对性,再基于相对性视角将创新点解构为3个构成要素,形成"管理类论文创新点=创新参照点+创新内容+创新过程证明"的认识,然后阐释如何在论文的不同位置展示... 详细信息

让管理类论文具有创新点是研究者必须做却又很难做的事。归纳出创新点的本质为相对性,再基于相对性视角将创新点解构为3个构成要素,形成"管理类论文创新点=创新参照点+创新内容+创新过程证明"的认识,然后阐释如何在论文的不同位置展示构成要素,以便让读者容易感知论文的价值所在。

关键词：创新点创新相对性创新参照点反常现象管理研究方法

Uniform boundary Harnack principle for rotationally symmetric Lvy processes in general open sets

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Science China Mathematics 2012年第11期55卷 2317-2333页

作者： KIM Panki song RenMing VONDRACEK Zoran Department of Mathematical Sciences and Research Institute of Mathematics Seoul National University Seoul 151-747 Korea Department of Mathematics University of Illinois Urbana IL 61801 USA Department of Mathematics University of Zagreb Zagreb Croatia

In this paper we prove the uniform boundary Harnack principle in general open sets for harmonic functions with respect to a large class of rotationally symmetric purely discontinuous Levy processes.

关键词： Levy processes subordinate Brownian motion harmonic functions boundary Harnack principle Poisson kernel

Validation of the Pretreatment Neutrophil-to-Lymphocyte Ratio as a Prognostic Factor in a Large Cohort of Chinese Patients with Upper Tract Urothelial Carcinoma

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Chinese Medical Journal 2017年第17期130卷 2063-2068页

作者： Zhen-peng Cao Bao Guan Guang-Zhi Zhao Dong Fang Geng-Yan Xiong Xue-song Li Li-Qun Zhou Department of Urology Peking University First Hospital Institute of Urology Peking University National Urological Cancer Centre Beijing 100034 China

Background：The pretreatment neutrophil-to-lymphocyte ratio （NLR） has been reported to be a prognostic factor in various types of *** aim of this study was to investigate the prognostic value of pretreatment NLR in a large cohort of Chinese patients with upper tract urothelial carcinoma （UTUC）.Methods：We retrospectively analyzed the medical data of 656 UTUC patients who underwent radical nephroureterectomy （RNU） from 2001 to 2011 at Peking University First *** operating characteristic （ROC） curve analysis was performed to calculate the optimal cutoffpoint of pretreatment ***-and multi-variate analyses were used to identify the prognostic factors for cancer-specific survival （CSS） and intravesical recurrence-free survival （IVRFS）.Results：The optimal cutoff point of pretreatment NLR was 2.40 by ROC curves,by which patients with high NLR （NLR 〉2.40） and low NLR （NLR 〈2.40） accounted for 314 （47.9%） and 342 （52.1%） patients,*** with a high pretreatment NLR tended to have high tumor grades （x2 =15.725,P〈 0.001）,high tumor stages （x2 =25.416,P〈 0.001）,tumor sizes 〉5 cm （x2 =8.213,P=0.005）,ipsilateral hydronephrosis （x2 =4.624,P =0.033）,and concomitant carcinoma in situ （CIS）（x2 =9.517,P =0.003）.A high pretreatment NLR （hazard ratio [HR] =1.820,P=0.001）,main tumor diameter 〉5 cm （HR =1.789,P =0.009）,lymph node metastasis （HR =1.863,P =0.024）,and high tumor stage （HR =1.745,P 〈 0.001） independently predicted poor CSS after surgery,while only concomitant carcinoma in situ （CIS）（HR =2.164,P =0.034）,ureteroscopy before surgery （HR =1.701,P =0.015）,and high tumor grade （HR =1.645,P =0.018） were independent predictors of IVRFS after ***：The pretreatment NLR was related to some adverse clinicopathological features and was an independent predictor of CSS,although not IVRFS,in Chinese UTUC patients.

关键词： Neutrophil-to-Lymphocyte Ratio Prognosis Upper Tract Urothelial Carcinoma

COUPLING ANALYSES OF FRAGILE ECO-ENVIRONMENT IN THE WEST OF THE songNEN PLAIN

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Chinese Geographical Science 2001年第3期11卷 61-67页

作者： Chang-chun song Wei Deng Xin-shan song Zhao-qing Luan Changchun Institute of Geography the Chinese Academy of Sciences Changchun P. R. China

The fragile eco-environment is a special type of ecosystem,its response to the change of environmental condi -tions is very *** it is rather prone to be disturbed under unfav orable *** activity h as greatly changed the geo-chemical process in the ecosystem,thus caused a series o f positive and negative *** t he ecosys-tem,especially in the fragile eco-e nvironment,different systems and r egimes are interconnected and *** the suntainable development of ecosystem and the protection and rational utilization of resources,it is of great impor-tance to study these internal relati onships and seek rational regulatio n and control *** paper tak es the fragile eco-environment in the west of the songnen Plain as an *** on th e study of the topograph,physiognom y,soil,vegetation and their geographic distribution in the landscape,th e paper explains the structure of the ecologic land-scape and quantifies the ecologic ge o-chemical processes under differe nt landscape *** additio n,the paper al-so tries making coupling analyses of the ecologic succession and the landscape geochemical *** in the pa-per,some research results are given.

关键词： west of the songnen Plain fragile eco-environment ecologic structure coupling of ecologic factors