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Examining the Effect of Hydroalcoholic Extract of Dracaena cinnabari on Sex Hormones and Ovarian and Uterine Tissues of Rats

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World Journal of Traditional Chinese Medicine 2024年第2期10卷 213-219页

作者： Elham Najafi bahareh Babaei Hoolari Akbar Karimi Aliasghar Pilehvarian Department of Cellular Biology Genesis Evolution-Develoment Isfahan Payame Noor University IsfahanIran Department of Anatomy School of MedicineTehran University of Medical SciencesTehranIran Department of Biology Group Faculty Member of Isfahan Payame Noor UniversityIsfahanIran

Introduction: Dracaena cinnabari is considered a rich source of phytochemicals used widely in traditional medicine. In the present study, the effect of D. cinnabari hydraulic extract on the reproductive system of female rats was investigated. Methods: The samples were randomly divided into four groups(six samples in each group), including three treatment groups and one control group, and all samples were kept at the same conditions. Hydraulic extract of D. cinnabari and injected intraperitoneally daily for 10 days, while physiological serum was used for injection in to the control group. After 10 days of injection, estrogen and progesterone levels were measured by enzyme immunoassay technique. After dissection, the ovaries and uterine tissues were isolated for histological examination, and tissue changes were carefully examined. Results: The results revealed that the levels of estrogen and progesterone in experimental Groups 2 and 3 had a significant increase(P < 0.001). Regarding tissue changes, a significant increase was observed in epithelial thickness(P < 0.001), number of corpus luteum(P < 0.01), and Graafian follicle(P < 0.01) in doses of 100 and 150 mg/kg. Conclusions: Based on the results, it seems that D. cinnabari extract has an effect on the ovarian follicles.

关键词： Dracaena cinnabari herbal medicine ovarian tissues reproductive sex hormones

Antifouling Properties of Electrospun Polymeric Coatings Induced by Controlled Surface Morphology

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ENERGY & ENVIRONMENTAL MATERIALS 2024年第6期7卷 409-419页

作者： Favrin, Fabio L. Zavagna, Lorenzo Sestini, Matteo Esin, Semih Azimi, bahareh Labardi, Massimiliano Milazzo, Mario Gallone, Giuseppe Batoni, Giovanna Danti, Serena Univ Pisa Dept Civil & Ind Engn Largo Lucio Lazzarino 2 I-56122 Pisa Italy Univ Pisa Dept Translat Res & New Technol Med & Surg Via San Zeno 35-39 I-56123 Pisa Italy Massachusetts Inst Technol MIT Dept Civil & Environm Engn Massachusetts Ave 77 Cambridge MA 02139 USA Inst Chem & Phys Proc IPCF Natl Res Council CNR Pisa Res Area Via Moruzzi 1 I-56124 Pisa Italy

Nosocomial infections affect implanted medical devices and greatly challenge their functional outcomes, becoming sometimes life threatening for the patients. Therefore, aggressive antibiotic therapies are administered, which often require the use of last-resort drugs, if the infection is caused by multi-drug-resistant bacteria. Reducing the risk of bacterial contamination of medical devices in the hospitals has thus become an emerging issue. Promising routes to control these infections are based on materials provided with intrinsic bactericidal properties (i.e., chemical action) and on the design of surface coatings able to limit bacteria adhesion and fouling phenomena (i.e., physical action), thus preventing bacterial biofilm formation. Here, we report the development and validation of coatings made of layer-by-layer deposition of electrospun poly(vinylidene fluoride-co-trifluoro ethylene) P(VDF-TrFE) fibers with controlled orientations, which ultimately gave rise to antifouling surfaces. The obtained 10-layer surface morphology with 90 degrees orientation fibers was able to efficiently prevent the adhesion of bacteria, by establishing a superhydrophobic-like behavior compatible with the Cassie-Baxter regimen. Moreover, the results highlighted that surface wettability and bacteria adhesion could be controlled using fibers with diameter comparable to bacteria size (i.e., achievable via electrospinning process), by tuning the intra-fiber spacing, with relevant implications in the future design of biomedical surface coatings.

关键词： additive manufacturing Escherichia coli fibers Poly(vinylidene fluoride-co-trifluoro ethylene) P(VDF-TrFE) Pseudomonas aeruginosa superhydrophobic IN-VITRO MICRO SUPERHYDROPHOBICITY INFECTION RISK NANO

Outcomes of surgical correction of Peyronie’s disease with plaque excision and grafting: Comparison of testicular tunica vaginalis graft versus bovine pericardium graft

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Asian Journal of Urology 2024年第3期11卷 497-503页

作者： Ali Eslahi Faisal Ahmed Mohammad Reza Askarpour Hossein-Ali Nikbakht Iman Shamohammadi Payam Ghasemi Hanieh Alimardani bahareh Ebrahimi Department of Urology School of MedicineShiraz University of Medical SciencesShirazIran Shiraz Geriatric Research Center Shiraz University of Medical SciencesShirazIran Urology Research Center Al-Thora General HospitalDepartment of UrologySchool of MedicineIbb University of Medical SciencesIbbYemen Social Determinants of Health Research Center Health Research InstituteBabol University of Medical SciencesBabolIran

Objective:Peyronie’s disease(PD)is an abnormal wound healing in the penile tunica *** fibrotic plaque excision,different graft materials have been used to repair the defects,but the optimal graft remains *** study aimed to compare the functional outcomes of testicular tunica vaginalis grafts and bovine pericardium grafts in patients with severe ***:A retrospective comparative study was conducted on 33 PD patients undergoing partial plaque excision and grafting from September 2015 to May *** patients were divided into two groups depending on the type of graft *** 15 patients in Group B,testicular tunica vaginalis grafts were used to repair the defect,while for 18 patients in Group A,bovine pericardium grafts were *** of the patient’s age,comorbidities,sexual function,penile curvature,postoperative complications,need for further treatment,change in penile length,and satisfaction were gathered and compared between the *** function was evaluated using the 5-item version of the International Index of Erectile Function(IIEF-5),and a functional less than 20-degree penile curvature after surgery was considered a successful ***:There was no difference in age,comorbidities,degree of curvature,perioperative IIEF-5,operative time,plaque size,or complication *** surgery,a statistically significant improvement in curvature degree(p<0.05)and satisfactory penile appearance(p<0.05)were seen in both groups without any superiority between the two groups(p=0.423 and p=0.840,respectively).With a 30-month follow-up,the IIEF-5 was consistent in both groups,with no statistical significance between the groups(p=0.492).The main change in penile length during the operation was increased and still positive in the last follow-up in both groups without statistical significance(p=0.255 and p=0.101,respectively).Conclusion:Partial plaque excision and corporoplasty with both testicular tunica vaginalis or bovine pericard

关键词： Peyronie's disease Plaqueexcision Testiculartunica vaginalis graft Bovinepericardium graft

Investigating the genetic diversity of several varieties of Iranian tomato (Solanum lycopersicum) using RAPD and ISSR molecular markers

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Food and Health 2024年第4期6卷 19-26页

作者： bahareh Ahang Sanaz Pashapour Aida Ghasemi Abbas Zabihi Department of Biology Faculty of Basic SciencesIslamic Azad UniversityRashtBranchRasht 0098813Iran Department of Pharmacology and toxicology Faculty of Pharmacy and Pharmaceutical SciencesIslamic Azad UniversityMedical Sciences BranchTehranIran School of Medicine Medical University of HamedanHamedanIran

Background:Numerous studies have demonstrated the existence of approximately 7,500 genetic tomato varieties ***,it is crucial to assess the genetic diversity among tomato *** study aimed to investigate the genetic diversity of selected Iranian tomato cultivars(Solanum lycopersicum)using RAPD and ISSR molecular ***:Ten RAPD primers and ten ISSR primers were employed to assess the genetic diversity among 10 tomato cultivars:Matin,RFT 112,Hirad,Golsar,Raha,Hengam,Hedah,Fasa,JS12,and *** analysis involved the UPGMA algorithm and NTYSYSpc ***:RAPD analysis revealed close genetic proximity between Fasa and JS12,as well as between Raha and ***,the RFT 112,Hengam,Hirad,and Emerald cultivars exhibited significant genetic diversity within this *** primer analysis identified Hengam as the most diverse variety,while Matin,Emerald,and Vibrid,as well as Raha and JS12,displayed genetic similarities with minimal observed ***,the overall analysis of the cultivars using RAPD and ISSR markers indicated that Hengam exhibited the highest diversity among all the ***,Raha and JS12 demonstrated limited diversity in this ***:This research demonstrates substantial genetic diversity among the investigated tomato varieties,with Hengam displaying the highest diversity within this ***,ISSR markers proved more effective in determining genetic diversity in tomato plants.

关键词： Solanum lycopersicum tomato genetic diversity RAPD ISSR

Secure Resource Allocation in Device-to-Device Communications Underlaying Cellular Networks

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China Communications 2022年第8期19卷 149-167页

作者： Hossein Ghavami bahareh Akhbari Faculty of Electrical Engineering K.N.Toosi University of TechnologyTehranIran

With increasing the demand for transmitting secure information in wireless networks,deviceto-device(D2D)communication has great potential to improve system *** a well-known security risk is eavesdropping in D2D communication,ensuring information security is quite *** this paper,we first obtain the closed-forms of the secrecy outage probability(SOP)and the secrecy ergodic capacity(SEC)for direct and decodeand-forward(DF)relay *** results are presented to verify the theoretical results,and these results show the cases that the DF relay mode improves security performance compared to the direct mode at long distances between the transmitter and receiver ***,we look into the optimization problems of secure resource allocation in D2D communication to maximize the SEC and to minimize the SOP by considering the strictly positive secrecy capacity constraint as a mixed-integer non-linear programming(MINLP)*** the continue,we convert the MINLP to convex ***,we solve this program with a dual method and obtain an optimal solution in the direct and DF relay modes.

关键词： D2D communication Secrecy ergodic capacity Secrecy outage probability Secrecy resource allocation Convex optimization

A Two-stage Adaptive Robust Model for Residential Micro-CHP Expansion Planning

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Journal of Modern Power Systems and Clean Energy 2021年第4期9卷 826-836页

作者： Fatemeh Teymoori Hamzehkolaei Nima Amjady bahareh Bagheri Department of Electrical Engineering Semnan UniversitySemnanIran

This paper addresses the planning problem of residential micro combined heat and power (micro-CHP) systems (including ‎micro-generation units, auxiliary boilers, and thermal storage tanks) considering the associated technical and economic factors. Since the accurate values of the thermal and electrical loads of this system cannot be exactly predicted for the planning horizon, the thermal and electrical load uncertainties are modeled using a two-stage ‎adaptive robust optimization method based on a ‎polyhedral uncertainty set. A solution method, which is composed of column-and-constraint generation (C&CG) algorithm ‎and block coordinate descent (BCD) method, is proposed to efficiently solve this adaptive robust optimization model. Numerical results ‎from a practical case study show the effective performance of the proposed adaptive robust model for residential micro-CHP planning and its solution method.

关键词： Micro combined heat and power(micro-CHP)planning two-stage adaptive robust optimization model block coordinate descent method polyhedral uncertainty set

Statistical design and kinetic and thermodynamic studies of Ni(Ⅱ) adsorption on bentonite

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Journal of Central South University 2017年第7期24卷 1529-1536页

作者： bahareh Sadeghalvad Amir Reza Azadmehr Hassan Motevalian Department of Mining&Metallurgical Engineering Amirkabir University of TechnologyTehranIran

The adsorption of the bentonite toward Ni(II) from aqueous solution was studied to obtain optimum conditions,equilibrium model,thermodynamic and kinetic *** method was used to evaluate maximum amount of adsorbed Ni(II).In this work,p H of solution during stirring,contact time,initial Ni(II) concentration,particle size of bentonite and amount of bentonite were considered as effective parameters which should be *** increase of temperature has negative effect on the Ni(II) *** equilibrium data were correlated well with Freundlich and Dubinin–Radushkevich isotherm models the correlation coefficients of which are(R^2) 0.994 and 0.971,*** model indicates heterogeneous and chemical absorption or ion exchange *** values of thermodynamic parameters such as ΔH°,ΔS° and ΔG° of nickel adsorption reveal that it is a spontaneous,exothermic and associative *** experimental data fit the pseudo-second-order kinetic very well with correlation coefficient(R^2) more than 0.995.

关键词： bentonite adsorption experimental design optimum condition equilibrium

Role of heat balance on the microstructure evolution of cold spray coated AZ31B with AA7075

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Journal of Magnesium and Alloys 2021年第4期9卷 1467-1478页

作者： bahareh Marzbanrad Mohammad Hadi Razmpoosh Ehsan Toyserkani Hamid Jahed Mechanical and Mechatronics Engineering Department University of WaterlooCanada

A promising solid-state coating mechanism based on the cold spray technique provides highly advantageous conditions on thermal-sensitive magnesium *** study the effect of heat balance in cold spray coating on microstructure,experiments were designed to successfully coat AA7075 on AZ31B with two different heat balance conditions to yield a coated sample with tensile residual stress and a sample with compressive residual stress in both coating and *** effects of coating temperature on the microstructure of magnesium alloy and the interfaces of coated samples were then analyzed by SEM,EBSD,TEM in high-and low-heat input coating *** interface of the AA7075 coating and magnesium alloy substrate under both conditions consists of a narrow-band layer with very fine grains,followed by columnar grains of magnesium that have grown perpendicular to the *** higher temperatures,this layer became *** intermetallic phase was detected at the interface under either *** is shown that the microstructure of the substrate was affected by coating temperature,leading to stress relief,dynamic recrystallization and even dynamic grain growth of magnesium under high *** the heat input and increasing the heat transfer decreased microstructural changes in the substrate.

关键词： Cold spraying Heat balance Microstructural analysis Coating interface Magnesium Alloy AZ31B Residual Stress

Structural and Electronic Properties of Cyclic Peptide-gold Nanoparticle as a Drug Delivery System

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Chinese Journal of Structural Chemistry 2019年第4期38卷 566-580页

作者： KHOSHBAYAN bahareh MORSALI Ali BOZORGMEHR Mohammad Reza Department of Chemistry Mashhad Branch Islamic Azad University MashhadIran & Research Center for Animal Development Applied BiologyBranch Islamic Azad University

Using Au6 cluster and cyclooctaglycine model for gold nanoparticle(AuNP) and cyclic peptide(CP), twelve configurations for the functionalization of cyclic peptide-gold nanoparticle(CPAuNP) with gemcitabine(GEM) anticancer drug were investigated(CPAuNP/GEM1-12). Structural and electronic properties have been studied in gas phase and aqueous solution at M06-2 X/6-31 g(d,p). The energetic stability of CPAuNP/GEM1-12 was confirmed by the calculation of binding energies. Since the solubility of drug, CP and AuNP increases in CPAuNP/GEM1-12, cyclic peptide-gold nanoparticle could be used as an appropriate drug delivery system. Quantum molecular descriptors such as electrophilicity power and global hardness demonstrated that the reactivity of CP and GEM drug increases in CPAuNP/GEM1-12 configurations. The AIM analysis for CPAuNP/GEM1-12 indicated that the Au-L(L = H, O, F, C, N) interactions and intermolecular hydrogen bonds play important roles in this drug delivery system. All Au-Au and some of Au-L interactions are related to medium interactions. The most stable configurations are those in which GEM drug is parallel to the CPAuNP and interacts simultaneously with AuNP and CP.

关键词： gold nanoparticle gemcitabine cyclic peptide AIM analysis nanocarrier